[A cross-over study on the effectiveness of ofloxacin and ciprofloxacin administered orally].

Abstract:

:Efficacy of Oral Ofloxacin and Ciprofloxacin. Cross-over Study. The efficacy of the 4-quinolones ciprofloxacin (CPX) and ofloxacin (OFX) was studied in a cross-over study. Twenty out-patients with cystic fibrosis and chronic colonization of the respiratory tract with Pseudomonas aeruginosa were treated for ten days with OFX, then another ten days with CPX, and vice versa. Drug concentrations in serum and sputum were assayed. The patients' clinical and laboratory parameters were monitored. The side-effects that appeared did not require interrupting treatment. The serum and sputum concentrations were found to be above the minimal inhibitory concentration. Although P. aeruginosa was not eliminated by the therapy, two-thirds of the patients showed improvement during the infection that could be observed clinically and in laboratory measurements. Oral treatment with OFX and CPX is efficacious.

journal_name

Infection

journal_title

Infection

authors

Kurz CC,Marget W,Harms K,Bertele RM

doi

10.1007/BF01645207

subject

Has Abstract

pub_date

1986-01-01 00:00:00

pages

S82-6

eissn

0300-8126

issn

1439-0973

journal_volume

14 Suppl 1

pub_type

临床试验,杂志文章,随机对照试验
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    authors: Wenzler-Röttele S,Dettenkofer M,Schmidt-Eisenlohr E,Gregersen A,Schulte-Mönting J,Tvede M

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    abstract::The efficacy of cefodizime (CDZ) in upper urinary tract infections (UUTI) and complicated lower urinary tract infections (LUTI) was assessed by analysis of the combined results of five clinical trials. Doses of CDZ 1 g i.m. daily, 1 x 2 g i.v. or i.m. and 2 x 2 g i.v. were investigated; comparative agents were cefurox...

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    pub_type: 杂志文章

    doi:10.1007/BF01709945

    authors: Hofstetter AG

    更新日期:1992-01-01 00:00:00

  • Evaluation of S. aureus ID, a chromogenic agar medium for the detection of Staphylococcus aureus.

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    doi:10.1007/s15010-006-5094-8

    authors: Diederen BM,van Leest CM,van Duijn I,Willemse P,van Keulen PH,Kluytmans JA

    更新日期:2006-04-01 00:00:00

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    abstract::The minimum inhibitory concentrations (MIC) of ciprofloxacin were determined for 441 uropathogens from patients with complicated and/or hospital acquired urinary tract infections (UTI). None of the Enterobacteriaceae was resistant (MIC > or = 4 mg/l), but 21.7% of enterococci, 28.3% of Pseudomonas spp. and 38.5% of st...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01793576

    authors: Naber KG,Witte W,Bauernfeind A,Wiedemann B,Wagenlehner F,Klare I,Heisig P

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  • Eikenella corrodens brain abscess after repeated periodontal manipulations cured with imipenem and neurosurgery.

    abstract::Eikenella corrodens is a facultatively anaerobic gram-negative rod that colonizes the oral cavity and very rarely produces central nervous system (CNS) infections. Frontal lobe abscesses are occasionally associated with a dental source of infection. We report a case of an adult man with overzealous dental cleaning hab...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-002-2004-6

    authors: Asensi V,Alvarez M,Carton JA,Lago M,Maradona JA,Asensi JM,Arribas JM

    更新日期:2002-08-01 00:00:00

  • A prospective study on infectious mononucleosis in childhood--symptoms, serology, Epstein-Barr-Virus specific leukocyte migration inhibition.

    abstract::The clinical course, serological changes and the development of the specific cell-mediated immune response to Epstein-Barr-Virus (EBV), measured in terms of leukocyte migration inhibition, were followed in 40 children suffering from an EBV infection. The patients were followed for between six and 24 months. Although t...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01640763

    authors: Timár L,Budai J,Koller M

    更新日期:1982-01-01 00:00:00

  • Assays of cephalosporin antibiotics administered prophylactically in open heart surgery. Determination of serum and tissue levels before, during and after cardiopulmonary bypass.

    abstract::Twenty-eight patients who underwent open-heart surgery were divided into three groups, each of which received a different antibiotic from the cephalosporin series (cephalotin, cefazolin or cefamandole) in order to prevent infection. All antibiotics were given via intravenous infusion in a dosage of 2 g prior to surger...

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    pub_type: 杂志文章

    doi:10.1007/BF01641087

    authors: Eigel P,Tschirkov A,Satter P,Knothe H

    更新日期:1978-01-01 00:00:00

  • Characteristics and outcome of 16 periprosthetic shoulder joint infections.

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    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-012-0360-4

    authors: Achermann Y,Sahin F,Schwyzer HK,Kolling C,Wüst J,Vogt M

    更新日期:2013-06-01 00:00:00

  • Specific anti cross-infection measures may help to prevent viral contamination of dental unit waterlines: a pilot study.

    abstract:BACKGROUND:In recent years, several reports have suggested, but never definitely demonstrated that dental units (DU) could be potential sources of viral cross-infections sustained by viral agents including HBV, HCV and HIV. This work aims at assessing the risk of HCV cross-infection by dental unit water lines (DUWLs). ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-008-7246-5

    authors: Artini M,Scoarughi GL,Papa R,Dolci G,De Luca M,Orsini G,Pappalardo S,Costerton JW,Selan L

    更新日期:2008-10-01 00:00:00

  • Management of a Mycobacterium immunogenum infection of a peritoneal dialysis catheter site.

    abstract::Mycobacterium immunogenum is a member of the rapidly growing non-tuberculous mycobacteria and is a relatively new species identified within this group. An 81-year-old immune-competent male was diagnosed with M. immunogenum infection of his peritoneal dialysis catheter exit site and surrounding soft tissue. To our know...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-018-1199-0

    authors: Shenoy A,El-Nahal W,Walker M,Chopra T,Townsend G,Heysell S,Eby J

    更新日期:2018-12-01 00:00:00

  • Sporopachydermia cereana fungaemia in refractory leukaemia presenting as breakthrough infection during micafungin therapy.

    abstract::The Sporopachydermia cereana species lives in decaying stems of cactus and is exceptionally rare as a human pathogen. A 57-year-old man with therapy-refractory acute promyelocytic leukaemia developed severe neutropaenia. After about 3 weeks of micafungin used as prophylaxis, he developed high fever, multiple pulmonary...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-012-0402-y

    authors: Chan TS,Hwang YY,To KK,Kwong YL

    更新日期:2013-06-01 00:00:00

  • Hospitalization rates for complicated and uncomplicated chickenpox in a poorly vaccined pediatric population.

    abstract:BACKGROUND:A retrospective study was conducted to provide epidemiological data on hospitalization for complicated and uncomplicated chickenpox in a pediatric population. METHODS:The study analyzed hospitalization cases for chickenpox, among all the 31 Tuscan hospitals, during the period 1997-2003. RESULTS:Globally, 6...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-007-6248-z

    authors: Bonsignori F,Chiappini E,Frenos S,Peraldo M,Galli L,de Martino M

    更新日期:2007-12-01 00:00:00

  • Correction to: Mucormycosis in hospitalized patients at a tertiary care center in Lebanon: a case series.

    abstract::The spelling of the name "Ali Bazarbachi" was incorrect. ...

    journal_title:Infection

    pub_type: 杂志文章,已发布勘误

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    authors: El Zein S,El-Sheikh J,Zakhem A,Ibrahim D,Bazarbachi A,Kanj SS

    更新日期:2018-12-01 00:00:00

  • Ceftizoxime (FK 749) in vitro antibacterial activity.

    abstract::The minimal inhibitory concentrations of ceftizoxime, cefotaxime, moxalactam, cefoperazone, cefotiam and cefamandole were determined against various species of gram-negative bacteria and against Staphylococcus aureus. Ceftizoxime was more active against Enterobacteriaceae than cefamandole, cefotiam and cefoperazone an...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01641024

    authors: Husson MO,Courcol R,Izard D,Leclerc H

    更新日期:1984-01-01 00:00:00

  • In vitro activity of clarithromycin and its 14-hydroxy-metabolite against 203 strains of Haemophilus influenzae.

    abstract::The in vitro activity of clarithromycin alone and in combination with its primary human metabolite, 14-hydroxy-clarithromycin, was determined against 203 strains of Haemophilus influenzae. Microdilution broth MICs and MBCs of both clarithromycin and 14-hydroxy-clarithromycin were determined. The clarithromycin MIC50 w...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01704612

    authors: Bergeron MG,Bernier M,L'Ecuyer J

    更新日期:1992-05-01 00:00:00

  • First report of neonatal early-onset sepsis caused by multi-drug-resistant Raoultella ornithinolytica.

    abstract::Raoultella ornithinolytica is increasingly being isolated as a causative organism in human infections. Most of the infections caused by R. ornithinolytica are hospital acquired and occur in patients who are immunocompromised, had invasive procedures or have indwelling catheters. This is a first report of early onset n...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-017-1098-9

    authors: Abbas A,Ahmad I

    更新日期:2018-04-01 00:00:00

  • In vitro-activity of clavulanic acid and amoxicillin combined against amoxicillin-resistant bacteria.

    abstract::The ability of clavulanic acid to inactivate beta-lactamase was investigated using 47 amoxicillin-resistant bacteria. In the presence of 10 mg/l clavulanic acid most strains of staphylococci, Escherichia coli, Klebsiella and Proteus mirabilis became fully amoxicillin-sensitive. This effect of clavulanic acid was in mo...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01641472

    authors: Peters G,Pulverer G,Neugebauer M

    更新日期:1980-01-01 00:00:00

  • Thrombogenicity testing of central venous catheters in vitro.

    abstract::To date there have been no standard methods for assessing the thrombogenicity of central venous catheters. A procedure for testing the thrombogenicity of intravenous lines such as the silver-impregnated catheter by continuous blood flow in vitro was therefore developed. For this test, fresh blood was drawn from health...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF02561614

    authors: Böswald M,Lugauer S,Bechert T,Greil J,Regenfus A,Guggenbichler JP

    更新日期:1999-01-01 00:00:00

  • Prevalence rates of viral hepatitis infections in refugee Kurds from Iraq and Turkey.

    abstract:BACKGROUND:Since little is known about the burden of viral hepatitis in Kurds, the prevalence of infection with hepatitis A virus (HAV), hepatitis E virus (HEV), hepatitis B virus (HBV) and hepatitis C virus (HCV) was investigated in a sample of refugee Kurds from Iraq and Turkey. PATIENTS AND METHODS:A cross-sectiona...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-002-3100-3

    authors: Chironna M,Germinario C,Lopalco PL,Carrozzini F,Barbuti S,Quarto M

    更新日期:2003-03-01 00:00:00

  • Prevalence of hepatitis B virus infection in out-patient alcoholics.

    abstract::Sera from 192 out-patient alcoholics attending a clinic for the treatment of alcoholism were tested for hepatitis B surface antigen (HBsAg) and for antibodies to HBsAg and to hepatitis B core antigen (HBcAg). Three sera (1.5%) were positive for HBsAg. Of the remaining 189 alcoholics, 29 (15%) were positive for one or ...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01641674

    authors: Gluud C,Gluud B,Aldershvile J,Jacobsen A,Dietrichson O

    更新日期:1984-03-01 00:00:00

  • Hepatitis C virus infection in the Middle East and North Africa "MENA" region: injecting drug users (IDUs) is an under-investigated population.

    abstract:PURPOSE:Investigation of the injecting drug users (IDUs) population is becoming extremely critical and timely in light of the recent evidence that IDUs now act as the core of hepatitis C virus (HCV) epidemics in developed countries. The purpose of this article, therefore, is not only to review the epidemiology of HCV i...

    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/s15010-011-0236-z

    authors: Ramia S,Melhem NM,Kreidieh K

    更新日期:2012-02-01 00:00:00

  • Susceptibility to HIV/AIDS: an individual characteristic we can measure?

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    journal_title:Infection

    pub_type: 杂志文章,评审

    doi:10.1007/s15010-005-6305-4

    authors: Jülg B,Goebel FD

    更新日期:2005-06-01 00:00:00

  • A case of Capnocytophaga canimorsus sacral abscess in an immunocompetent patient.

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    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-014-0681-6

    authors: Joswig H,Gers B,Dollenmaier G,Heilbronner R,Strahm C

    更新日期:2015-04-01 00:00:00

  • The frequency of Mycoplasma pneumoniae antibodies in a Calabrian population.

    abstract::The epidemiological survey was carried out in a Calabrian population in order to ascertain the incidence of antibodies to Mycoplasma pneumoniae. In the past it has been felt that this infection does not occur in Southern Italy. We have found an incidence in our survey equal to that of the other countries. It was impos...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01638421

    authors: Calisto ML,Farina W,Picerno I,Ceccarelli G

    更新日期:1976-01-01 00:00:00

  • Quantitation of HCV viraemia by branched DNA signal amplification in patients treated with alpha-interferon--a longitudinal study.

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    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/BF01743362

    authors: Iuliano R,Pizzigallo AM,Alecci A,Barsanti L,Trovato R,Forastieri G,Lico S,Palmieri C,Brizzi M,Marino N,Mecocci L,Mazzotta F,Ceccherini-Nelli L

    更新日期:1996-07-01 00:00:00

  • Effect of pH on the in vitro activity of and propensity for emergence of resistance to fluoroquinolones, macrolides, and a ketolide.

    abstract::Antibiotic activity against common respiratory pathogens can be affected by the pH of the medium (in vitro) or the bodily fluid (in vivo) in which bacteria are present. The ionized fraction of an antibiotic is not able to efficiently penetrate bacterial or mammalian membranes, reducing the quantity of molecules able t...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-005-8206-y

    authors: Dalhoff A,Schubert S,Ullmann U

    更新日期:2005-12-01 00:00:00

  • 'Lost in Nasal Space': Staphylococcus aureus sepsis associated with Nasal Handkerchief Packing.

    abstract:INTRODUCTION:Staphylococcus aureus frequently causes infections in outpatient and hospital settings and can present as a highly variable entity. Typical manifestations are endocarditis, osteoarticular infections or infection of implanted prostheses, intravascular devices or foreign bodies. A thorough diagnostic evaluat...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-018-1221-6

    authors: Koehler P,Jung N,Kochanek M,Lohneis P,Shimabukuro-Vornhagen A,Böll B

    更新日期:2019-04-01 00:00:00

  • M. pneumoniae and C. pneumoniae are no relevant pathogens in critically ill patients with hospital-acquired respiratory tract infections.

    abstract:PURPOSE:To assess the incidence of Mycoplasma pneumoniae and Chlamydia pneumoniae in the pathogenesis of hospital-acquired respiratory tract infections (RTIs) in critically ill patients. METHODS:This is a retrospective cohort study of all ICU-patients ≥ 18 years with RTI who underwent conventional culture techniques a...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-019-01273-x

    authors: Hagel S,Schmitt S,Kesselmeier M,Baier M,Welte T,Ewig S,Pletz MW

    更新日期:2019-06-01 00:00:00

  • Procalcitonin and C-reactive protein levels in community-acquired pneumonia: correlation with etiology and prognosis.

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    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s150100050049

    authors: Hedlund J,Hansson LO

    更新日期:2000-03-01 00:00:00

  • Emergence of SCCmec type IV as the most common type of methicillin-resistant Staphylococcus aureus in a university hospital.

    abstract:BACKGROUND:The epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) has dramatically changed over the last decade by the emergence of community-associated MRSA (CA-MRSA). Recent studies indicate that these strains have already spread to hospitals. To evaluate if SCCmec type IV and Panton-Valentine leukoci...

    journal_title:Infection

    pub_type: 杂志文章

    doi:10.1007/s15010-008-7430-7

    authors: Strandén AM,Frei R,Adler H,Flückiger U,Widmer AF

    更新日期:2009-02-01 00:00:00