Hyperuricemia in Asian psoriatic arthritis patients.

Abstract:

AIM:It is generally accepted that hyperuricemia is commonly associated with psoriatic arthritis (PsA). However, variations in ethnicity, diet and habitat may contribute to differences in prevalence and risk factors for hyperuricemia in PsA patients. Moreover, Asian specific data is deficient. The primary objective of the present study was to determine the prevalence of hyperuricemia among PsA patients. The secondary objective was to explore its associated risk factors. METHODS:This was a multi-center, cross-sectional observational study of 160 PsA patients from local Rheumatology clinics. Serum uric acid (SUA) level and other clinical parameters were measured and hyperuricemia was defined as SUA level greater or equal to 360 umol/L in females and 420 umol/L in males. RESULTS:Forty-nine of 160 patients (30.6%) had hyperuricemia, of which 32 were men, 17 were women. Among those with hyperuricemia, mean SUA level was 500.7 ± 95.9 umol/L and 427.8 ± 83.1 umol/L in males and females, respectively. Univariate analysis found: (i) overweight status; (ii) obesity; (iii) Psoriasis Area and Severity Index; (iv) body surface area; (v) severe skin involvement, as being potentially associated with hyperuricemia. Regression model identified overweight status increased the likelihood of hyperuricemia in PsA, with an odds ratio of 4.4 (95% CI: 2.0-9.5). Furthermore, there was moderately positive correlation (r = 0.37) between body mass index (BMI) and SUA level. No associations were found between arthritis conditions and duration, lipid profile, creatinine clearance; and hyperuricemia. CONCLUSION:A significant proportion of PsA patients had asymptomatic hyperuricemia. It was closely related with BMI, which represented metabolic dysregulation; but not with severity of skin disease, joint involvement or renal function.

journal_name

Int J Rheum Dis

authors

Lai TL,Yim CW,Wong PY,Leung MC,Ng WL

doi

10.1111/1756-185X.13265

subject

Has Abstract

pub_date

2018-04-01 00:00:00

pages

843-849

issue

4

eissn

1756-1841

issn

1756-185X

journal_volume

21

pub_type

杂志文章,多中心研究
  • Leflunomide in clinical practice. A retrospective observational study on use of leflunomide in New Zealand.

    abstract:AIM:The aim was to study the side-effect profile and the survival characteristics of leflunomide used in a regional patient population in New Zealand (NZ). METHOD:  Patients were identified using special authority forms (SAFs) that had been prospectively filed from January 2001 to June 2007. Statistical analysis of su...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/j.1756-185X.2011.01637.x

    authors: Jagoda JS,Rajapakse CN

    更新日期:2011-10-01 00:00:00

  • Multiple myeloma presenting with musculoskeletal manifestations: a case report.

    abstract::Multiple myeloma (MM) is a malignant plasma cell disorder. Musculoskeletal and skin manifestations of this disorder are rare. Here we report a case of a young male patient presenting with polyarthritis and skin rash resembling vasculitis. Detailed investigations revealed that he was suffering from multiple myeloma in ...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/j.1756-185X.2010.01526.x

    authors: Agarwal D,Sharma A,Kapoor S,Garg SR,Malaviya AN

    更新日期:2010-08-01 00:00:00

  • Taiwan Rheumatology Association consensus recommendations for the management of axial spondyloarthritis.

    abstract:AIM:To establish guidelines for the clinical management of axial spondyloarthritis that take into account local issues and clinical practice concerns for Taiwan. METHOD:Overarching principles and recommendations were established by consensus among a panel of rheumatology and rehabilitation experts, based on analysis o...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,评审

    doi:10.1111/1756-185X.13752

    authors: Wei JC,Liu CH,Tseng JC,Hsieh LF,Chen CH,Chen HH,Chen HA,Chen YC,Chou CT,Liao HT,Lin YC,Luo SF,Yang DH,Yeo KJ,Tsai WC,Taiwan Rheumatology Association (TRA).

    更新日期:2020-01-01 00:00:00

  • Osteoarthritis of the knees in the COPCORD world.

    abstract::This paper examines and summarizes data on knee osteoarthritis (AO) in Community Oriented Program For Control Of Rheumatic Disorders (COPCORD) publications. A literature search was made through PubMed, Google, Proceedings of Asia-Pacific League of Associations for Rheumatology (APLAR) congresses, and Abstracts from AP...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,评审

    doi:10.1111/j.1756-185X.2011.01615.x

    authors: Haq SA,Davatchi F

    更新日期:2011-05-01 00:00:00

  • Association between COX-2 and 15-PGDH polymorphisms and SLE susceptibility.

    abstract:AIMS:Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease. Prostaglandins E2 (PGE2), the product of the cyclo-oxygenase 2 (COX-2) enzyme, has critical roles in the etiology of autoimmune diseases. PGE2 level is controlled by a balance between its synthesis mediator (COX-2 enzyme) and its cata...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13808

    authors: Sandoughi M,Saravani M,Rokni M,Nora M,Mehrabani M,Dehghan A

    更新日期:2020-05-01 00:00:00

  • Differentiation of patented crystalline glucosamine sulfate from other glucosamine preparations will optimize osteoarthritis treatment.

    abstract::Symptomatic slow-acting drugs for osteoarthritis (SYSADOAs) are recommended for the medium- to long-term management of knee osteoarthritis (OA) due to their abilities to control pain, improve function and delay joint structural changes. Among SYSADOAs, evidence is greatest for the patented crystalline glucosamine sulf...

    journal_title:International journal of rheumatic diseases

    pub_type: 社论,评审

    doi:10.1111/1756-185X.13068

    authors: Saengnipanthkul S,Waikakul S,Rojanasthien S,Totemchokchyakarn K,Srinkapaibulaya A,Cheh Chin T,Mai Hong N,Bruyère O,Cooper C,Reginster JY,Lwin M

    更新日期:2019-03-01 00:00:00

  • Assessing the construct validity of clinical tests to identify sacroiliac joint inflammation in patients with non-radiographic axial spondyloarthritis.

    abstract:AIM:Magnetic resonance imaging (MRI) can be used to identify sacroiliac joint (SIJ) inflammation and provide an earlier diagnosis of nonradiographic axial spondyloarthritis (nrAxSpA). However, MRI is frequently a resource-limited examination. Our aim was to assess if a set of physical clinical tests can identify SIJ in...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13606

    authors: Castro MP,Stebbings SM,Milosavljevic S,Pedersen SJ,Bussey MD

    更新日期:2019-08-01 00:00:00

  • Psychometric assessment of the Japanese version of the Revised Fibromyalgia Impact Questionnaire: reliability and validity.

    abstract:AIM:To assess the psychometric properties of the Japanese version of the Revised Fibromyalgia Impact Questionnaire (JFIQR) in fibromyalgia (FM) patients. METHOD:The reliability and validity of the JFIQR were assessed using online data collected from Japanese FM patients. Reliability was evaluated based on test-retest ...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.12574

    authors: Isomura T,Nakamura I,Kawaguchi M,Sato E,Inuzuka K,Osada K,Nishioka K,Hayakawa K

    更新日期:2017-09-01 00:00:00

  • Validity and reliability of the unsupported upper-limb exercise test in individuals with rheumatoid arthritis.

    abstract:BACKGROUND:Rheumatoid arthritis (RA) is a chronic disease which affects the performance of the upper extremities. There is no method to evaluate the specific upper extremity endurance of individuals with this disease. The unsupported upper-limb exercise test (UULEX) is a performance test that evaluates upper extremity ...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13720

    authors: Cetin SY,Basakci Calik B,Ayan A,Cavlak U

    更新日期:2019-11-01 00:00:00

  • Neonatal lupus erythematosus: a review of 123 cases in China.

    abstract:AIM:To analyze the clinical features, outcomes and prognosis of neonatal lupus erythematosus (NLE) in China. METHOD:We reviewed 12 NLE cases at the Peking Union Medical College Hospital and compared the data with 111 cases reported in China between 1990 and 2014. The Chinese medical journal search engines used in this...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,评审

    doi:10.1111/1756-185X.12652

    authors: Li YQ,Wang Q,Luo Y,Zhao Y

    更新日期:2015-09-01 00:00:00

  • Effects of patient satisfaction and confidence on the success of treatment of combined rheumatic disease and interstitial lung disease in a multidisciplinary outpatient clinic.

    abstract:OBJECTIVES:Multidisciplinary discussions (MDDs) have emphasized improve medical services and outcomes. We used a multidisciplinary approach to explore whether patient emotional satisfaction and confidence affected treatment outcomes in rheumatic disease (RD)-related interstitial lung disease (ILD). METHODS:From Decemb...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13331

    authors: Jeong SO,Uh ST,Park S,Kim HS

    更新日期:2018-08-01 00:00:00

  • High seroprevalence of human herpesvirus 8 infection in patients with systemic lupus erythematosus.

    abstract:AIM:Systemic lupus erythematosus (SLE) is an autoimmune disease that is associated with genetic and environmental factors and microbial infection. With respect to microbial infection, the Epstein-Barr virus (EBV) has been a widely discussed issue in recent decades. Human herpesvirus 8 (HHV-8) belongs to the same γ-herp...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.12193

    authors: Tung YC,Ke LY,Tsai SM,Lu PL,Tsai WC

    更新日期:2013-12-01 00:00:00

  • Assessment of the relationship between aortic stiffness and left ventricular functions with echocardiography in patients with Sjögren's syndrome.

    abstract:BACKGROUND AND AIM:Capable of multi-organ involvement in Sjogren's syndrome (SS), cardiac findings of pulmonary effusion, left ventricular diastolic dysfunction and pulmonary hypertension are seen in patients with SS. Aortic stiffness (AS) reflects the mechanical tension and elasticity of the aorta. In this study, our ...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.12258

    authors: Ciçek OF,Bayram NA,Ayhan H,Erten S,Aslan AN,Sarı C,Ozen MB,Bİlen E,Bastuğ S,Durmaz T,Keleş T,Bozkurt E

    更新日期:2014-07-01 00:00:00

  • Prevalence and risk of metabolic syndrome in patients with systemic lupus erythematosus: A meta-analysis.

    abstract:PURPOSE:To conduct a systematic review and meta-analysis assessing the prevalence of metabolic syndrome (MetS) in patients with systemic lupus erythematosus (SLE) and the association between SLE and MetS. METHOD:A database search of PubMed, the Cochrane Library, EMBASE, China National Knowledge Infrastructure (CNKI), ...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/1756-185X.13153

    authors: Sun C,Qin W,Zhang YH,Wu Y,Li Q,Liu M,He CD

    更新日期:2017-08-01 00:00:00

  • Efficacy and safety of tofacitinib in patients with active rheumatoid arthritis: review of key Phase 2 studies.

    abstract::Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). Here, the safety and efficacy data from five Phase 2 studies of tofacitinib in patients with RA are summarized. Tofacitinib 1-30 mg twice daily was investigated, as monotherapy and in combination with methotrexate, in patient...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,评审

    doi:10.1111/1756-185X.12901

    authors: Fleischmann R,Kremer J,Tanaka Y,Gruben D,Kanik K,Koncz T,Krishnaswami S,Wallenstein G,Wilkinson B,Zwillich SH,Keystone E

    更新日期:2016-12-01 00:00:00

  • A rheumatologic approach to granulomatous mastitis: A case series and review of the literature.

    abstract:AIM:Idiopathic granulomatous mastitis (IGM) is an enigmatic inflammatory breast disorder. IGM responds to immunomodulatory treatment and may be associated with systemic manifestations such as arthritis and erythema nodosum. These patients are increasingly referred to rheumatologists for management, but IGM is rarely di...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.14065

    authors: Ringsted S,Friedman M

    更新日期:2021-02-01 00:00:00

  • Treat-to-target in rheumatoid arthritis: Evaluating the patient perspective using the Patient Opinion Real-Time Anonymous Liaison system: The RA T2T PORTAL study.

    abstract:OBJECTIVES:To determine the level of agreement among patients with rheumatoid arthritis (RA) with the principles and recommendations of the treat-to-target (T2T) initiative in New Zealand (NZ) and to further explore specific patient opinions via online iterative surveys. METHODS:Participants with RA were recruited fro...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13514

    authors: Benham H,Rutherford M,Kirby S,Stebbings S,White D,Sim D,Harrison A

    更新日期:2019-05-01 00:00:00

  • Soluble CD25 in serum: a potential marker for subclinical macrophage activation syndrome in patients with active systemic onset juvenile idiopathic arthritis.

    abstract:OBJECTIVE:Laboratory and immunological abnormalities seen in overt macrophage activation syndrome (MAS) may be observed in patients with untreated new onset systemic onset juvenile idiopathic arthritis (SoJIA). We investigated the prevalence of clinical and traditional laboratory markers of MAS as well as soluble CD163...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.12196

    authors: Reddy VV,Myles A,Cheekatla SS,Singh S,Aggarwal A

    更新日期:2014-03-01 00:00:00

  • A study of the prevalence of sicca symptoms and secondary Sjögren's syndrome in patients with rheumatoid arthritis, and its association to disease activity and treatment profile.

    abstract:AIM:To examine the prevalence of sicca symptoms and secondary Sjögren's syndrome (sSS) in rheumatoid arthritis (RA) patients, and the impact of sSS on disease activity and treatment profile in RA patients. METHODS:Three hundred and seven RA patients responding positive to at least one of the questions in a questionnai...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/j.1756-185X.2012.01717.x

    authors: Haga HJ,Naderi Y,Moreno AM,Peen E

    更新日期:2012-06-01 00:00:00

  • Impact of subclinical synovitis in ankles and feet detected by ultrasonography in patients with rheumatoid arthritis.

    abstract:OBJECTIVE:To investigate the impact of subclinical synovitis detected by ultrasonography (US) on the ankles and feet of patients with rheumatoid arthritis. METHODS:We retrospectively reviewed the data of patients (n = 59) who underwent US. RESULTS:The functional ability and quality of life (QoL) of patients in the su...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13399

    authors: Inamo J,Kaneko Y,Sakata K,Takeuchi T

    更新日期:2019-01-01 00:00:00

  • Gout: an Asia-Pacific update.

    abstract::Even though, Hippocrates recognized gout as an affection of older men and a product of high living long back in 5th century BC, this painful condition promises to accompany humanity to the 21st century. The incidence is progressively rising and females are also affected in the modern era. There are also regional and e...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,评审

    doi:10.1111/1756-185X.13103

    authors: Paul BJ,James R

    更新日期:2017-04-01 00:00:00

  • Differential expression of natural killer activating and inhibitory receptors in patients with newly diagnosed systemic lupus erythematosus.

    abstract:AIM:Systemic lupus erythematosus (SLE) presents as the abnormal activation and over-proliferation of immune competent cells. Few studies have characterized the role of natural killer (NK) and NK T (NKT) cells in the pathogenesis of SLE, and therefore a consensus has not been reached as yet. METHOD:Thirty-two patients ...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.12289

    authors: Ye Z,Ma N,Zhao L,Jiang ZY,Jiang YF

    更新日期:2016-06-01 00:00:00

  • Risk factors for herpes zoster infection among Filipinos with systemic lupus erythematosus.

    abstract:AIM:To identify clinical risk factors associated with herpes zoster (HZ) infections in systemic lupus erythematosus (SLE). METHODS:A case-control study of HZ infection was performed in SLE patients seen at the University of Santo Tomas Lupus Clinics from 2009-2014. Cases were matched 1:2 to SLE controls without HZ inf...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13725

    authors: Zamora LD,Collante MTM,Navarra SV

    更新日期:2020-02-01 00:00:00

  • Tocilizumab for severe COVID-19 pneumonia: Case series of 5 Australian patients.

    abstract:AIM:To describe the first Australian cases of severe acute respiratory syndrome-coronavirus 2 (SARS-CoV2) disease (COVID-19) pneumonia treated with the interleukin-6 receptor antagonist tocilizumab. METHODS:Retrospective, open-label, real-world, uncontrolled, single-arm case series conducted in 2 tertiary hospitals in...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1111/1756-185X.13913

    authors: West TA,Malik S,Nalpantidis A,Tran T,Cannon C,Bhonagiri D,Chan K,Cheong E,Wan Sai Cheong J,Cheung W,Choudhury F,Ernest D,Farah CS,Fernando S,Kanapathipillai R,Kol M,Murfin B,Naqvi H,Shah A,Wagh A,Ojaimi S,Franku

    更新日期:2020-08-01 00:00:00

  • Effects of Arctium lappa L. (Burdock) root tea on inflammatory status and oxidative stress in patients with knee osteoarthritis.

    abstract:AIM:This study was designed to examine the effect of Burdock root tea on inflammatory markers and oxidative stress indicators in patients with knee osteoarthritis (OA). METHODS:Thirty-six patients (10 men and 26 women) aged 50-70 years old with knee osteoarthritis referred to the Physical Medicine and Rehabilitation D...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/1756-185X.12477

    authors: Maghsoumi-Norouzabad L,Alipoor B,Abed R,Eftekhar Sadat B,Mesgari-Abbasi M,Asghari Jafarabadi M

    更新日期:2016-03-01 00:00:00

  • Traditional Chinese medicine Bushen-Jianpi-Huoxue decoction prevents diabetic osteoporosis in rats via Wnt and nuclear factor-kappa B signaling pathways.

    abstract:AIM:The aim of this study was to evaluate the therapeutic effect of a traditional Chinese medicine (TCM), Bushen-Jianpi-Huoxue decoction (BJHD), on diabetic osteoporosis (DOP) and the action mechanisms likely mediated by nuclear factor-kappa B (NF-κB) and Wnt signaling pathways. METHODS:Fifty-five male Wistar rats wer...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13050

    authors: Zhang Y,Liu M,Li H,Chen Z,Liang N,Xu J,Zhang X,Zhang Y

    更新日期:2017-08-01 00:00:00

  • The frequency of metabolic syndrome in women with rheumatoid arthritis and in controls.

    abstract:AIM:To compare the frequency of the metabolic syndrome and its components in a sample of patients with rheumatoid arthritis (RA) and controls. METHODS:This case control study was performed on 188 women over 18 years old: 92 RA patients and 96 healthy controls, from 2006 to 2008. Blood pressure, height, weight and wais...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/j.1756-185X.2011.01595.x

    authors: Karimi M,Mazloomzadeh S,Kafan S,Amirmoghadami H

    更新日期:2011-08-01 00:00:00

  • Body mass index and hand osteoarthritis susceptibility: an updated meta-analysis.

    abstract:AIM:Numerous epidemiologic studies have evaluated the association between overweight and hand osteoarthritis; However, the existing results are inconsistent. METHODS:Systematic searches were performed and reference lists from the retrieved trials were searched. This meta-analysis and meta-regression was executed to id...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/1756-185X.12895

    authors: Jiang L,Xie X,Wang Y,Wang Y,Lu Y,Tian T,Chu M,Shen Y

    更新日期:2016-12-01 00:00:00

  • Remission in rheumatoid arthritis by different criteria does not converge over the inflammatory markers.

    abstract:OBJECTIVE:Remission is an ideal target in the management of rheumatoid arthritis (RA). We compared American College of Rheumatology (ACR) 1981 preliminary definition of remission, European League Against Rheumatism (EULAR) disease activity score of 28 joints - C-reactive protein (DAS28 (3)-CRP) and DAS28 (3)-ESR (eryth...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.12091

    authors: Chandrashekara S,Priyanka BU

    更新日期:2013-06-01 00:00:00

  • Evaluation of sleep quality in patients with ankylosing spondylitis and efficacy of anti-TNF-α therapy on sleep problems: A polisomnographic study.

    abstract:INTRODUCTION:This study was conducted to investigate the relationship between sleep quality (SQ) and disease activity (DA) in patients with ankylosing spondylitis (AS) and to evaluate the response to anti-tumor necrosis factor α (anti-TNF-α) therapy on sleep disorders. MATERIALS AND METHODS:A total of 34 patients who ...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13102

    authors: Karatas G,Bal A,Yuceege M,Firat H,Gurcay E,Ardic S,Cakci FA

    更新日期:2018-06-01 00:00:00