Abstract:
Purpose:Recent studies investigating new strategies to modulate the immune system have utilized animal models of liver transplantation (LT). However, the anhepatic phase (AHP) remains a crucial problem in LT. The aim of the present study is to introduce a technique for successful orthotopic LT in cynomolgus monkeys using an early-reperfusion strategy. Methods:Orthotopicallo-LT was performed with seven donor/recipient pairs of cynomolgus monkeys. Results:In 2 recipients, liver allografts were perfused after suprahepatic inferior vena cava (SHIVC), portal vein (PV), and infrahepatic inferior vena cava (IHIVC) anastomosis. To reduce the time of AHP in five recipients, liver allografts ware perfused after SHIVC and PV anastomosis while the IHIVC was not anastomosed. In the latter strategy, the AHP was reduced from 46 minutes to 31 minutes and a 24-hour survival rate of 80% was achieved. Conclusion:Our results indicate that an early-reperfusion strategy can be successfully used to establish a LT model in cynomolgus monkeys with a consistently high rate of animal survival.
journal_name
Ann Surg Treat Resjournal_title
Annals of surgical treatment and researchauthors
Lee KW,Cho CW,Park H,Choi GS,Park JB,Kim SJdoi
10.4174/astr.2018.94.1.8subject
Has Abstractpub_date
2018-01-01 00:00:00pages
8-12issue
1eissn
2288-6575issn
2288-6796journal_volume
94pub_type
杂志文章abstract:Purpose:Preoperative chemoradiation therapy (CRT) has become the standard treatment for patients with locally advanced rectal cancer, 15%-30% of patients still progress while being treated with CRT. The aim of this study was to identify as important biomarker of poor response and evaluate the mechanism associated with ...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2019.97.2.83
更新日期:2019-08-01 00:00:00
abstract:Purpose:Evaluating the risk of lymph node metastasis (LNM) is critical for determining subsequent treatments following endoscopic resection of T1 colorectal cancer (CRC). This study analyzed histopathologic risk factors for LNM in patients with T1 CRC. Methods:This study involved 745 patients with T1 CRC who underwent...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2017.93.5.266
更新日期:2017-11-01 00:00:00
abstract:PURPOSE:To analyze the benefit and feasibility of this procedure compared with those of open method. METHODS:Abdominal procedure includes laparoscopic gastric mobilization, celiac axis lymph node dissection, formation of the gastric tube, and pyloromyotomy. The actual procedure performed during open surgery is the sam...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2015.89.3.117
更新日期:2015-09-01 00:00:00
abstract:PURPOSE:The aim of this study is to assess the long-term results of laparoscopic common bile duct exploration (LCBDE) and validate its effectiveness as a primary treatment modality for CBD stone. METHODS:A retrospective review of the medical records of 157 patients who underwent LCBDE from 1997 to 2011 was conducted. ...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2014.86.1.1
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:It is believed that blood from the superior mesenteric vein and splenic vein mixes incompletely in the portal vein and maintains a streamline flow influencing its anatomic distribution. Although several experimental studies have demonstrated the existence of streamlining, clinical studies have shown conflicting...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2017.92.5.348
更新日期:2017-05-01 00:00:00
abstract:PURPOSE:Ultrasound-guided fine needle aspiration (US-FNA) in thyroid nodules is presently most commonly used to identify whether these nodules are benign or malignant. However, atypical or follicular lesions of undetermined significance (AUS/FLUS), as categorized in the Bethesda System for reporting the results of FNA,...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2016.90.4.201
更新日期:2016-04-01 00:00:00
abstract:PURPOSE:Downstaging after chemoradiotherapy (CRT) for rectal cancer usually occurs. The present study aimed to evaluate pathologic y-stage (yp-stage) and its influence on local recurrence and systemic recurrence in rectal cancer patients treated with CRT followed by surgical resection. METHODS:We retrospectively analy...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2015.88.1.15
更新日期:2015-01-01 00:00:00
abstract:Purpose:Clinically suspected T4 stage colon cancer from a preoperative exam is often diagnosed as T3 stage colon cancer pathologically after surgery, raising concerns about understaging. The aims of this study were to compare the survival of clinical T3 and T4 colon cancer patients who had received a pathologic T3 stag...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2020.99.1.37
更新日期:2020-07-01 00:00:00
abstract:Purpose:Infection remains the main cause of morbidity and mortality in liver transplantation (LT) recipients; however infection is notoriously difficult to diagnose because its usual signs and symptoms of infection may be masked or absent. This study comprises an analysis of bacterial infections in the early period aft...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2018.94.3.154
更新日期:2018-03-01 00:00:00
abstract:Purpose:Given the long history of investigation into cancer and its relevance to the lymph node (LN), it would be meaningful to plot the trends of research on cancer-related LN. Methods:Queries such as "cancer," "lymph node," and "cancer and lymph node" were submitted to PubMed to collect articles on cancer and LN pub...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2020.99.5.305
更新日期:2020-11-01 00:00:00
abstract:Purpose:Gastric emptying may influence the quality of life of patients who undergo distal gastrectomy. Little is known, however, about gastric emptying after distal gastrectomy. The aim of our study was to investigate gastric emptying patterns after distal gastrectomy. Methods:This gastric-emptying study investigated ...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2017.93.6.310
更新日期:2017-12-01 00:00:00
abstract:PURPOSE:Little is known about the clinicopathological features of early mucinous gastric carcinoma (MGC). The purpose of this study was to compare the clinicopathological features and prognosis between patients with early MGC and those with early nonmucinous gastric carcinoma (NMGC). METHODS:We reviewed the records of...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2014.87.1.5
更新日期:2014-07-01 00:00:00
abstract:PURPOSE:This study aimed to compare the learning curves and early postoperative outcomes for conventional laparoscopic (CL) and single incision laparoscopic (SIL) right hemicolectomy (RHC). METHODS:This retrospective study included the initial 35 cases in each group. Learning curves were evaluated by the moving averag...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2015.88.5.269
更新日期:2015-05-01 00:00:00
abstract:Purpose:Skin grafts have been widely used in managing extensive chest wall defects after mastectomy for advanced breast cancer. However, their durability and tolerability to radiotherapy is still controversial. A thoracoabdominal (TA) flap with a few technical refinements can safely transfer a larger flap while minimiz...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2019.97.4.168
更新日期:2019-10-01 00:00:00
abstract:Purpose:Recent studies have suggested microscopic positive resection margin should be revised according to the presence of tumor cells within 1mm of the margin surface in resected specimens of pancreatic cancer. However, the clinical meaning of this revised margin status for R1 resection margin was not fully clarified....
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2019.96.1.19
更新日期:2019-01-01 00:00:00
abstract::Endovascular aneurysm repair is a minimally invasive, durable and effective alternative to open surgery for treatment of abdominal aortic aneurysms (AAA). However, in patients who do not have an adequate sealing zone, open surgical repair is required, which may increase mortality and morbidity. An alternative treatmen...
journal_title:Annals of surgical treatment and research
pub_type:
doi:10.4174/astr.2014.86.5.274
更新日期:2014-05-01 00:00:00
abstract::The concept of complete mesocolic excision and central vascular ligation for colonic cancer has been recently introduced. The paper describes a technique of right-sided complete mesocolic excision and intracorporeal anastomosis by using a single-port robotic approach with an additional conventional robotic port. We pe...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2016.91.4.212
更新日期:2016-10-01 00:00:00
abstract::[This corrects the article on p. 396 in vol. 92, PMID: 28580343.]. ...
journal_title:Annals of surgical treatment and research
pub_type: 已发布勘误
doi:10.4174/astr.2017.93.2.118
更新日期:2017-08-01 00:00:00
abstract:Purpose:To compare high and low inferior mesenteric artery (IMA) ligation in a large number of patients, and investigate the short-term and long-term outcomes. Methods:This retrospective study compared outcomes between high IMA ligation and low IMA ligation with dissection of lymph nodes (LNs) around the IMA origin. A...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2019.97.5.254
更新日期:2019-11-01 00:00:00
abstract:Purpose:There has been an increasing trend in the use of contralateral prophylactic mastectomy (CPM) among women diagnosed with unilateral breast cancer or mutations in BRCA1 or BRCA2 to reduce the occurrence of contralateral breast cancer. This study aimed to examine trends in the CPM rate according to clinicopatholog...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2019.97.3.113
更新日期:2019-09-01 00:00:00
abstract::Vitelline veins are a pair of embryonic structures. The veins develop the portal vein system. Serious problems occur if the vitelline vein does not regress and becomes an aneurysm. Thrombus formation in the vitelline vein aneurysm could lead to portal vein thrombosis and portal hypertension unless promptly and correct...
journal_title:Annals of surgical treatment and research
pub_type:
doi:10.4174/astr.2015.89.6.334
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:Management of appendicitis in children has always been an issue in pediatric surgery. Both diagnostic methods and treatment vary significantly among medical centers, and little consensus exists in many aspects of the care for patients with appendicitis. Here, we assessed the value of drain insertion after appen...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2015.88.6.341
更新日期:2015-06-01 00:00:00
abstract:PURPOSE:We aimed to develop an effective system for surgical site infection (SSI) surveillance and examine the current domestic state of SSIs for common abdominal surgeries in Korea. METHODS:The Korean Surgical Site Infection Surveillance (KOSSIS) program was developed as an SSI surveillance system. A prospective mult...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2015.88.3.119
更新日期:2015-03-01 00:00:00
abstract:Purpose:The anatomical variations of the thyroid gland including separate thyroidal remnant at the thyrothymic area are of significance during thyroid surgery for "total" thyroidectomy, and for recurrent goitre. In the present study, we aimed to detect the separate rests of thyroidal tissue in the thyrothymic region. ...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2020.98.3.111
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:To determine the prevalence of thrombophilia in Korean patients with an arterial thromboembolism (ATE) or a venous thromboembolism (VTE), and to evaluate the characteristic of VTE in patients with thrombophilia. METHODS:Hospital records of 294 patients (228 with VTE, 66 with ATE) including two foreign ones (me...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2016.90.6.340
更新日期:2016-06-01 00:00:00
abstract::Pediatric arterial aneurysm is rare disease. Among them, idiopathic-congenital arterial aneurysm is extremely rare. This is a case report of right common iliac artery idiopathic aneurysm with absence of right external iliac artery. A 4-year-old girl who had been complaining of intermittent abdominal pain since 2 years...
journal_title:Annals of surgical treatment and research
pub_type:
doi:10.4174/astr.2016.91.5.265
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:The aim of this study was to find risk factors for early recurrence (ER) and early death (ED) after liver resection for colorectal cancer liver metastasis (CRCLM). METHODS:Between May 1990 and December 2011, 279 patients underwent liver resection for CRCLM at Korea University Medical Center. They were assigned...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2016.90.5.257
更新日期:2016-05-01 00:00:00
abstract:PURPOSE:Bariatric surgery has become more prevalent owing to the worldwide obesity epidemic. With the growing number of bariatric procedures performed annually, the requirement for revisional and secondary operations is increasing accordingly. This study aimed to evaluate the initial experience of revisional bariatric ...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2014.86.6.295
更新日期:2014-06-01 00:00:00
abstract:Purpose:Increased robotic surgery is attended by increased reports of complications, largely due to limited operative view and lack of tactile sense. These kinds of obstacles, which seldom occur in open surgery, are challenging for beginner surgeons. To enhance robotic surgery safety, we created an augmented reality (A...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2018.95.6.297
更新日期:2018-12-01 00:00:00
abstract::We present the case of young female patient presenting with acute onset abdominal pain. Abdominopelvic CT revealed herniation through the foramen of Winslow. The patient was transferred to our hospital and underwent laparoscopic exploration. Though spontaneous reduction was detected, segmental resection of the impacte...
journal_title:Annals of surgical treatment and research
pub_type:
doi:10.4174/astr.2017.92.2.113
更新日期:2017-02-01 00:00:00