Abstract:
BACKGROUND:Risk for neurodevelopmental delay in infants and children with CHD is well established, but longer-term outcomes are equivocal. A meta-analysis was conducted to establish whether cognitive deficits remain beyond childhood - into teenage and young adult years. Methods and results A total of 18 unique samples, involving adolescents, teenagers, and adults with CHD significant enough to require invasive intervention, and sourced through searches of Web of Science, MEDLINE, CINAHL Plus, and PsychInfo, met the inclusion criteria. These included the use of standardised neuropsychology tests across 10 domains of cognitive functioning and the reporting of effect size differences with controls. Reports of patients with chromosomal or genetic abnormalities were excluded. Pooled effect sizes suggested no significant differences between CHD samples and controls in terms of general intellectual ability and verbal reasoning. However, small-medium effects sizes were noted (0.33-0.44) and were statistically significant within the domains of non-verbal reasoning, processing speed, attention, auditory-verbal memory, psychomotor abilities, numeracy, and literacy with executive functioning also emerging as significant when one study outlier was excluded. We also included quality assurance statistics including Cochran's Q, T, and I2 statistics, leave-one-out analyses, and assessment of publication bias. These often suggested study variability, possibly related to the heterogeneity of diagnostic groups included, and different tests used to measure the same construct. CONCLUSIONS:Heterogeneity indicated that moderators affect cognitive outcomes in CHD. Nevertheless, deficits across cognitive domains were discerned, which are likely to have functional impact and which should inform practice with this clinical population.
journal_name
Cardiol Youngjournal_title
Cardiology in the youngauthors
Mills R,McCusker CG,Tennyson C,Hanna Ddoi
10.1017/S104795111700230Xsubject
Has Abstractpub_date
2018-03-01 00:00:00pages
421-431issue
3eissn
1047-9511issn
1467-1107pii
S104795111700230Xjournal_volume
28pub_type
杂志文章,meta分析abstract::Occlusion using coils is now the treatment of choice for closure of the patent arterial duct. The DuctOcclud (pfm AG, Cologne, Germany) device is a relatively new retrievable coil for such trans-catheter closure. This study expands on previously reported experience with this device, summarizes the advantages of the de...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s1047951102000793
更新日期:2002-10-01 00:00:00
abstract::This study evaluates clinical and epidemiological features of acute rheumatic fever using the data of last 25 years in our hospital in south-east of Turkey. The medical records of 377 patients with acute rheumatic fever admitted to Pediatric Cardiology Department of Çukurova University during 1993-2017 were retrospect...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951120001596
更新日期:2020-08-01 00:00:00
abstract::We describe a patient with the rare association of the heart in the left chest, congenitally corrected transposition, pulmonary atresia and an intact ventricular septum. There were associated fistulous communications between the morphologically left ventricle and the coronary arteries. Diagnosis was made by echocardio...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s1047951100009227
更新日期:2000-05-01 00:00:00
abstract::Supravalvular aortic stenosis is associated with the Williams-Beuren syndrome, but it also occurs in a non-syndromatic congenital form. An elastin gene mutation of chromosome 7q11.23 is responsible in both cases. The vascular features are identical. These patients have a higher risk of sudden death, particularly when ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951110001563
更新日期:2011-02-01 00:00:00
abstract::There exists a population of adults with undiagnosed coronary arterial lesions due to Kawasaki disease occurring before 1967. We report the clinical features in 6 adult males with coronary arterial lesions caused by presumed Kawasaki disease, whose dates of birth ranged from 1945 to 1963. The age of the diagnosed coro...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951107000169
更新日期:2007-02-01 00:00:00
abstract::This review includes a brief discussion, from the perspective of cardiac surgeons, of the rationale for creation and maintenance of multi-institutional databases of outcomes of congenital heart surgery, together with a history of the evolution of such databases, a description of the current state of the art, and a dis...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951108002813
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the relations between the P-wave dispersion and diastolic functions in type 1 diabetic children. PATIENTS:A total of 33 diabetic patients without any cardiovascular disease, with a mean age of 12.3 plus or minus 4.2 years, and 29 healthy controls, with a mean age of 1...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S104795110999031X
更新日期:2010-04-01 00:00:00
abstract::Children with a secundum atrial septal defect are usually asymptomatic and are referred for elective closure after 3-4 years of age; however, in premature infants with chronic lung disease, bronchopulmonary dysplasia, or pulmonary hypertension, increased pulmonary blood flow secondary to a left-to-right atrial shunt, ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951114002650
更新日期:2016-01-01 00:00:00
abstract::A two-year-old boy with a background history of Down syndrome and partial atrioventricular septal defect presented with acute respiratory distress requiring intubation and mechanical ventilation. He continued to deteriorate, despite ventilation; direct laryngoscopy, bronchoscopy, and computed tomography demonstrated s...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951114000468
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVE:The objective of the study was to identify incidence, aetiology, and outcomes of extubation failure in infants with shunt-dependent pulmonary blood flow at a single tertiary care, academic children's hospital. The second objective of this study was to determine the haemodynamic effects of transition of positi...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951112002181
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to report on the short-term and mid-term outcomes of preterm infants who underwent patent ductus arteriosus ligation through anterior mini-thoracotomy. METHODS:Data for 103 preterm infants who underwent patent ductus arteriosus clipping through an anterior mini-thoracotomy at the 2nd...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951121000032
更新日期:2021-01-28 00:00:00
abstract::The Fellowship Program of the Department of Cardiology at Boston Children's Hospital seeks to train academically oriented leaders in clinical care and laboratory and clinical investigation of cardiovascular disease in the young. The core clinical fellowship involves 3 years in training, comprising 24 months of clinica...
journal_title:Cardiology in the young
pub_type: 历史文章,杂志文章
doi:10.1017/S1047951116001712
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Complications at the vascular access sites are among the most common adverse events in congenital cardiac catheterization. The use of small-gauge catheters may reduce these events; however, other factors can contribute to the development of vascular complications. OBJECTIVES:To determine factors associated ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951111000989
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:The policy of early repair of patients with tetralogy of Fallot, irrespective of age, as opposed to initial palliation with a shunt, remains controversial. The aim of our study was to analyze the midterm outcome of primary early correction of tetralogy of Fallot. METHODS:Between 1996 and 2005, a total of 61 ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951108001960
更新日期:2008-04-01 00:00:00
abstract::In utero diagnosis of complex progressive cardiac disease such as hypoplastic left heart syndrome presents a novel opportunity for antepartum, intrapartum, and neonatal management. The clinical possibilities and potential for differing outcomes challenge the mother-foetus dyad with regard to informed consent. Previous...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951111001715
更新日期:2011-12-01 00:00:00
abstract::We report the case of a child with cor triatriatum dexter masquerading as Ebstein's anomaly on transthoracic echocardiography. This was attributed to a floppy membrane arising from the right atrium, protruding into the tricuspid valve and pushing the leaflets downwards, giving an impression of Ebstein's anomaly. The i...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951111000023
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:Efficient diagnosis of an underlying genetic aetiology in a patient with congenital heart disease is essential to optimising clinical care. Copy number variants are one aetiology of congenital heart disease; the majority are identifiable by targeted fluorescence in situ hybridisation or array comparative geno...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951113001868
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Absent arterial valve leaflets are rare anomalies. On the basis of our understanding of the normal development of the arterial valves, we draw inferences that might offer clues to their morphogenesis. METHODS:We describe the findings from four human fetal autopsies with so-called "absent" arterial valvar le...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951116000524
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:There is no standard dose or protocol for beta-blocker administration as preconditioning in children undergoing coronary CT angiography. METHODS:A total of 63 consecutive patients, with a mean age of 10.0±3.1 years, who underwent coronary CT angiography to assess possible coronary complications were enrolle...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S104795111800118X
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Care of children with functionally univentricular hearts is resource-intensive. OBJECTIVES:To analyse pregnancy and early post-natal outcomes of fetuses with functionally univentricular hearts in the setting of a low-middle-income country. METHODS:A retrospective study was conducted during the period of Ja...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951120002929
更新日期:2020-12-01 00:00:00
abstract::In Respiratory Syncytial Virus infection, the early identification of infants at risk for severe disease in order to potentially decrease morbidity could be considered a major goal. Current guidelines recommend only clinical observation for this purpose in infants without known comorbidities. However, recent evidence ...
journal_title:Cardiology in the young
pub_type: 信件
doi:10.1017/S1047951119002348
更新日期:2019-11-01 00:00:00
abstract::With the advent of improved medical and surgical care in congenital heart disease, there has been an increase in the number of patients who survive into adulthood, giving rise to a new patient population 'Adults with congenital heart disease'. In the past, morbidity and mortality were the primary concerns for this gro...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951113000747
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:Protocols for the placement of temporary pacing wires vary among institutions. Our current protocol is to selectively place temporary pacing wires in those patients who develop haemodynamically significant intra-operative arrhythmia. We wished to identify how effective our current protocol is at identifying w...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951114000043
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Perceived correlation between the coronary arterial anatomy in patients with complete transposition, and the outcome of the arterial switch procedure, has made preoperative identification of their patterns standard practice. PURPOSE:Our purpose was to assess the accuracy of preoperative echocardiographic id...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s1047951102000537
更新日期:2002-05-01 00:00:00
abstract::We report amiodarone-induced pulmonary toxicity in an 18-year-old boy who had undergone corrective surgery for tetralogy of Fallot 4 years earlier, and was treated with amiodarone because of recurrent malignant postoperative ventricular tachyarrhythmias. Toxicity was recognized on the basis of clinical features, chest...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s1047951100008441
更新日期:1999-03-01 00:00:00
abstract:BACKGROUND:Cardiovascular disease is a leading cause of morbidity and mortality in childhood cancer survivors. Cardiologists must be aware of risk factors and long-term follow-up guidelines, which have historically been the purview of oncologists. Little is known about paediatric cardiologists' knowledge regarding the ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S104795111900088X
更新日期:2019-06-01 00:00:00
abstract:INTRODUCTION:Exercise echocardiography assesses exercise-induced pulmonary hypertension. The upper normal limit of right ventricular systolic pressure during exercise is not well established. Our study aims to investigate the response of right ventricular systolic pressure in relation to aerobic capacity. METHODS AND ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951109990928
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Flow profiles are important determinants of fluid-vessel wall interactions. The aim of this study was to assess blood flow profiles in the aorta and pulmonary trunk in patients with transposition and different ventriculoarterial connection, and hence different mechanics of the coherent pump. ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951112002193
更新日期:2014-02-01 00:00:00
abstract::Traditional ambulatory rhythm monitoring in children can have limitations, including cumbersome leads and limited monitoring duration. The ZioTM patch ambulatory monitor is a small, adhesive, single-channel rhythm monitor that can be worn up to 2 weeks. In this study, we present a retrospective cross-sectional analysi...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951118001142
更新日期:2018-10-01 00:00:00
abstract::Innocent murmurs are common in childhood. They require accurate diagnosis to avoid unnecessary anxiety and/or restrictions. With this in mind, we studied prospectively children diagnosed by a paediatric cardiologist as having innocent murmurs to review the necessity of investigations in excluding organic abnormalities...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s104795110000963x
更新日期:2000-10-01 00:00:00