Emergence and Spread of Epidemic Multidrug-Resistant Pseudomonas aeruginosa.

abstract：:Orphan genes are defined as genes that lack detectable similarity to genes in other species and therefore no clear signals of common descent (i.e., homology) can be inferred. Orphans are an enigmatic portion of the genome because their origin and function are mostly unknown and they typically make up 10% to 30% of all...

journal_title：Genome biology and evolution

authors： Wissler L,Gadau J,Simola DF,Helmkampf M,Bornberg-Bauer E

更新日期：2013-01-01 00:00:00

abstract：:Cnidarians represent one of the few groups of venomous animals that lack a centralized venom transmission system. Instead, they are equipped with stinging capsules collectively known as nematocysts. Nematocysts vary in abundance and type across different tissues; however, the venom composition in most species remains ...

journal_title：Genome biology and evolution

authors： Macrander J,Broe M,Daly M

更新日期：2016-08-25 00:00:00

abstract：:Vomeronasal sensitivity is important for detecting intraspecific pheromonal cues as well as environmental odorants and is involved in mating, social interaction, and other daily activities of many vertebrates. Two large families of seven-transmembrane G-protein-coupled receptors, V1rs and V2rs, bind to various ligands...

journal_title：Genome biology and evolution

authors： Park SH,Podlaha O,Grus WE,Zhang J

更新日期：2011-01-01 00:00:00

abstract：:Seed storage proteins (SSP) in cereals provide essential nutrition for humans and animals. Genes encoding these proteins have undergone rapid evolution in different grass species. To better understand the degree of divergence, we analyzed this gene family in the subfamily Chloridoideae, where the genome of teff (Eragr...

journal_title：Genome biology and evolution

authors： Zhang W,Xu J,Bennetzen JL,Messing J

更新日期：2016-06-13 00:00:00

abstract：:Many insects rely on bacterial symbionts with tiny genomes specialized for provisioning nutrients lacking in host diets. Xylem sap and phloem sap are both deficient as insect diets, but differ dramatically in nutrient content, potentially affecting symbiont genome evolution. For sap-feeding insects, sequenced symbiont...

journal_title：Genome biology and evolution

authors： Bennett GM,Moran NA

更新日期：2013-01-01 00:00:00

abstract：:Cichlid fishes are an ideal model system for studying biological diversification because they provide textbook examples of rapid speciation. To date, there has been little focus on the role of gene regulation during cichlid speciation. However, in recent years, gene regulation has been recognized as a powerful force l...

journal_title：Genome biology and evolution

authors： Franchini P,Xiong P,Fruciano C,Meyer A

更新日期：2016-06-03 00:00:00

abstract：:The availability of spontaneously occurring genetic variants is an important driving force of biological evolution. Largely thanks to experimental investigations by microbial geneticists, we know today that several different molecular mechanisms contribute to the overall genetic variations. These mechanisms can be ass...

journal_title：Genome biology and evolution

authors： Arber W

更新日期：2011-01-01 00:00:00

abstract：:The colonization of novel environments often involves changes in gene expression, protein coding sequence, or both. Studies of how populations adapt to novel conditions, however, often focus on only one of these two processes, potentially missing out on the relative importance of different parts of the evolutionary pr...

journal_title：Genome biology and evolution

authors： Brown AP,Arias-Rodriguez L,Yee MC,Tobler M,Kelley JL

更新日期：2018-11-01 00:00:00

abstract：:African trypanosomiasis is a vector-borne disease of humans and livestock caused by African trypanosomes (Trypanosoma spp.). Survival in the vertebrate bloodstream depends on antigenic variation of Variant Surface Glycoproteins (VSGs) coating the parasite surface. In T. brucei, a model for antigenic variation, monoall...

journal_title：Genome biology and evolution

authors： Abbas AH,Silva Pereira S,D'Archivio S,Wickstead B,Morrison LJ,Hall N,Hertz-Fowler C,Darby AC,Jackson AP

更新日期：2018-09-01 00:00:00

abstract：:This study investigated long-term substitution rate differences using three calibration points, divergences between lobe-finned vertebrates and ray-finned fish, between mammals and sauropsids, and between holosteans (gar and bowfin) and teleost fish with amino acid sequence data of 625 genes for 25 bony vertebrates. T...

journal_title：Genome biology and evolution

authors： Takezaki N

更新日期：2018-07-01 00:00:00

abstract：:Each animal microRNA (miRNA) targets many genes for repression. Down-regulation of most of these targets is weak and has no detectable individual phenotypic effect. Whether this extensive weak repression is biologically relevant is a central issue in the debate on miRNA functionality. In the "small (target) pool" view...

journal_title：Genome biology and evolution

authors： Zhao Y,Lin P,Liufu Z,Yang H,Lyu Y,Shen X,Wu CI,Tang T

更新日期：2018-04-01 00:00:00

abstract：:Polyadenylation is a step of mRNA processing which is crucial for its expression and stability. The major polyadenylation signal (PAS) represents a nucleotide hexamer that adheres to the AATAAA consensus sequence. Over a half of human genes have multiple cleavage and polyadenylation sites, resulting in a great diversi...

journal_title：Genome biology and evolution

authors： Kainov YA,Aushev VN,Naumenko SA,Tchevkina EM,Bazykin GA

更新日期：2016-07-02 00:00:00

abstract：:Sex chromosomes have evolved independently in many different taxa, and so have mechanisms to compensate for expression differences on sex chromosomes in males and females. Different clades have evolved vastly different ways to achieve dosage compensation, including hypertranscription of the single X in male Drosophila...

journal_title：Genome biology and evolution

authors： Mahajan S,Bachtrog D

更新日期：2015-01-18 00:00:00

abstract：:The Bateson-Dobzhansky-Muller (BDM) model of reproductive isolation by genetic incompatibility is a widely accepted model of speciation. Because of the exceptionally rich biological information about the budding yeast Saccharomyces cerevisiae, the identification of BDM incompatibilities in yeast would greatly deepen o...

journal_title：Genome biology and evolution

authors： Li C,Wang Z,Zhang J

更新日期：2013-01-01 00:00:00

abstract：:The process of transcription is highly stochastic leading to cell-to-cell variations and noise in gene expression levels. However, key essential genes have to be precisely expressed at the correct amount and time to ensure proper cellular development and function. Studies in yeast and bacterial systems have shown that...

journal_title：Genome biology and evolution

authors： Vance KW,Woodcock DJ,Reid JE,Bretschneider T,Ott S,Koentges G

更新日期：2015-09-04 00:00:00

abstract：:Males and females of Artemia franciscana, a crustacean commonly used in the aquarium trade, are highly dimorphic. Sex is determined by a pair of ZW chromosomes, but the nature and extent of differentiation of these chromosomes is unknown. Here, we characterize the Z chromosome by detecting genomic regions that show lo...

journal_title：Genome biology and evolution

authors： Huylmans AK,Toups MA,Macon A,Gammerdinger WJ,Vicoso B

更新日期：2019-04-01 00:00:00

abstract：:Recent whole-genome approaches to microbial phylogeny have emphasized partitioning genes into functional classes, often focusing on differences between a stable core of genes and a variable shell. To rigorously address the effects of partitioning and combining genes in genome-level analyses, we developed a novel techn...

journal_title：Genome biology and evolution

authors： Narechania A,Baker RH,Sit R,Kolokotronis SO,DeSalle R,Planet PJ

更新日期：2012-01-01 00:00:00

abstract：:Campylobacter sputorum is a nonthermotolerant campylobacter that is primarily isolated from food animals such as cattle and sheep. C. sputorum is also infrequently associated with human illness. Based on catalase and urease activity, three biovars are currently recognized within C. sputorum: bv. sputorum (catalase neg...

journal_title：Genome biology and evolution

authors： Miller WG,Yee E,Chapman MH,Bono JL

更新日期：2017-06-01 00:00:00

abstract：:Rapid divergence of gene copies after duplication is thought to determine the fate of the copies and evolution of novel protein functions. However, data on how long the gene copies continue to experience an elevated rate of evolution remain scarce. Standard theory of gene duplications based on some level of genetic re...

journal_title：Genome biology and evolution

authors： Pich I Roselló O,Kondrashov FA

更新日期：2014-07-28 00:00:00

abstract：:Fish use olfaction to sense a variety of nonvolatile chemical signals in water. However, the evolutionary importance of olfaction in species-rich cichlids is controversial. Here, we determined an almost complete sequence of the vomeronasal type 2 receptor-like (OlfC: putative amino acids receptor in teleosts) gene clu...

journal_title：Genome biology and evolution

authors： Nikaido M,Suzuki H,Toyoda A,Fujiyama A,Hagino-Yamagishi K,Kocher TD,Carleton K,Okada N

更新日期：2013-01-01 00:00:00

abstract：:Insertion sequences (ISs) are mobile genetic elements in bacterial genomes. In general, intergenic IS elements are probably less deleterious for their hosts than intragenic ISs, simply because they have a lower likelihood of disrupting native genes. However, since promoters, Shine-Dalgarno sequences, and transcription...

journal_title：Genome biology and evolution

authors： Plague GR

更新日期：2010-01-01 00:00:00

abstract：:Immunity genes have repeatedly experienced natural selection during mammalian evolution. Galectins are carbohydrate-binding proteins that regulate diverse immune responses, including maternal-fetal immune tolerance in placental pregnancy. Seven human galectins, four conserved across vertebrates and three specific to p...

journal_title：Genome biology and evolution

authors： Ely ZA,Moon JM,Sliwoski GR,Sangha AK,Shen XX,Labella AL,Meiler J,Capra JA,Rokas A

更新日期：2019-09-01 00:00:00

abstract：:Chlorarachniophytes are unicellular marine algae with plastids (chloroplasts) of secondary endosymbiotic origin. Chlorarachniophyte cells retain the remnant nucleus (nucleomorph) and cytoplasm (periplastidial compartment, PPC) of the green algal endosymbiont from which their plastid was derived. To characterize the di...

journal_title：Genome biology and evolution

authors： Hopkins JF,Spencer DF,Laboissiere S,Neilson JA,Eveleigh RJ,Durnford DG,Gray MW,Archibald JM

更新日期：2012-01-01 00:00:00

abstract：:Isochores are large regions of relatively homogeneous nucleotide composition and are present in the genomes of all mammals and birds that have been sequenced to date. The newly sequenced genome of Anolis carolinensis provides the first opportunity to quantify isochore structure in a nonavian reptile. We find Anolis to...

journal_title：Genome biology and evolution

authors： Fujita MK,Edwards SV,Ponting CP

更新日期：2011-01-01 00:00:00

abstract：:Explaining the evolution of animals requires ecological, developmental, paleontological, and phylogenetic considerations because organismal traits are affected by complex evolutionary processes. Modeling a plurality of processes, operating at distinct time-scales on potentially interdependent traits, can benefit from ...

journal_title：Genome biology and evolution

authors： Lord E,Pathmanathan JS,Corel E,Makarenkov V,Lopez P,Bouchard F,Bhattacharya D,Antoine PO,Le Guyader H,Lapointe FJ,Bapteste E

更新日期：2019-09-01 00:00:00

abstract：:As most genes are shared between females and males, DNA methylation is assumed to play a crucial role in sex-biased gene expression. DNA methylation exclusively occurs at CpG dinucleotides, and therefore, we would expect that CpG density around transcription start sites (TSSs) relate to sex-biased gene expression. Her...

journal_title：Genome biology and evolution

authors： Tamagawa K,Makino T,Kawata M

更新日期：2017-05-01 00:00:00

abstract：:Although pooled-population sequencing has become a widely used approach for estimating allele frequencies, most work has proceeded in the absence of a proper statistical framework. We introduce a self-sufficient, closed-form, maximum-likelihood estimator for allele frequencies that accounts for errors associated with ...

journal_title：Genome biology and evolution

authors： Lynch M,Bost D,Wilson S,Maruki T,Harrison S

更新日期：2014-04-30 00:00:00

abstract：:The nearly neutral theory, which proposes that most mutations are deleterious or close to neutral, predicts that the ratio of nonsynonymous over synonymous substitution rates (dN/dS), and potentially also the ratio of radical over conservative amino acid replacement rates (Kr/Kc), are negatively correlated with effect...

journal_title：Genome biology and evolution

authors： Nabholz B,Uwimana N,Lartillot N

更新日期：2013-01-01 00:00:00

abstract：:Transposable elements (TEs) constitute a substantial portion of many eukaryotic genomes, and can in principle contribute to evolutionary innovation as well as genomic deterioration. Daphnia pulex serves as a useful model for studying TE dynamics as a potential cause and/or consequence of asexuality. We analyzed insert...

journal_title：Genome biology and evolution

authors： Jiang X,Tang H,Ye Z,Lynch M

更新日期：2017-02-01 00:00:00

abstract：:Gene duplication may be an important mechanism for the evolution of new functions and for the adaptive modulation of gene expression via dosage effects. Here, we analyzed the fate of gene duplicates for two strains of a novel group of cyanobacteria (genus Acaryochloris) that produces the far-red light absorbing chloro...

journal_title：Genome biology and evolution

authors： Miller SR,Wood AM,Blankenship RE,Kim M,Ferriera S

更新日期：2011-01-01 00:00:00