The Structure of a Conserved Telomeric Region Associated with Variant Antigen Loci in the Blood Parasite Trypanosoma congolense.

abstract：:Each animal microRNA (miRNA) targets many genes for repression. Down-regulation of most of these targets is weak and has no detectable individual phenotypic effect. Whether this extensive weak repression is biologically relevant is a central issue in the debate on miRNA functionality. In the "small (target) pool" view...

journal_title：Genome biology and evolution

authors： Zhao Y,Lin P,Liufu Z,Yang H,Lyu Y,Shen X,Wu CI,Tang T

更新日期：2018-04-01 00:00:00

abstract：:Homologous recombination is a major driver of bacterial speciation. Genetic divergence and host association are important factors influencing homologous recombination. Here, we study these factors for Campylobacter fetus, which shows a distinct intraspecific host dichotomy. Campylobacter fetus subspecies fetus (Cff) a...

journal_title：Genome biology and evolution

authors： Gilbert MJ,Duim B,van der Graaf-van Bloois L,Wagenaar JA,Zomer AL

更新日期：2018-03-01 00:00:00

abstract：:Venoms are among the most biologically active secretions known, and are commonly believed to evolve under extreme positive selection. Many venom gene families, however, have undergone duplication, and are often deployed in doses vastly exceeding the LD50 for most prey species, which should reduce the strength of posit...

journal_title：Genome biology and evolution

authors： Aird SD,Arora J,Barua A,Qiu L,Terada K,Mikheyev AS

更新日期：2017-10-01 00:00:00

abstract：:The conjugative virulence plasmid is a key component of the Rhodococcus equi accessory genome essential for pathogenesis. Three host-associated virulence plasmid types have been identified the equine pVAPA and porcine pVAPB circular variants, and the linear pVAPN found in bovine (ruminant) isolates. We recently charac...

journal_title：Genome biology and evolution

authors： MacArthur I,Anastasi E,Alvarez S,Scortti M,Vázquez-Boland JA

更新日期：2017-05-01 00:00:00

abstract：:The contribution of the transposons' promoter in the horizontal transfer process is quite overlooked in the scientific literature. To shed light on this aspect we have mimicked the horizontal transfer process in laboratory and assayed in a wide range of hosts (fly, human, yeast and bacteria) the promoter activity of t...

journal_title：Genome biology and evolution

authors： Palazzo A,Caizzi R,Viggiano L,Marsano RM

更新日期：2017-06-01 00:00:00

abstract：:Human-specific small insertions and deletions (HS indels, with lengths <100 bp) are reported to be ubiquitous in the human genome. However, whether these indels contribute to human-specific traits remains unclear. Here we employ a modified McDonald-Kreitman (MK) test and a combinatorial population genetics approach to...

journal_title：Genome biology and evolution

authors： Chen CH,Chuang TJ,Liao BY,Chen FC

更新日期：2009-10-20 00:00:00

abstract：:The identification of conserved syntenic regions enables discovery of predicted locations for orthologous and homeologous genes, even when no such gene is present. This capability means that synteny-based methods are far more effective than sequence similarity-based methods in identifying true-negatives, a necessity f...

journal_title：Genome biology and evolution

authors： Tang H,Bomhoff MD,Briones E,Zhang L,Schnable JC,Lyons E

更新日期：2015-11-11 00:00:00

abstract：:Acquisition of Elizabethkingia infections in intensive care units (ICUs) has risen in the past decade. Treatment of Elizabethkingia infections is challenging due to the lack of effective therapeutic regimens, leading to a high mortality rate. Elizabethkingia infections have long been attributed to Elizabethkingia meni...

journal_title：Genome biology and evolution

authors： Teo J,Tan SY,Liu Y,Tay M,Ding Y,Li Y,Kjelleberg S,Givskov M,Lin RT,Yang L

更新日期：2014-05-06 00:00:00

abstract：:Because of its highly repetitive nature, the human male-specific Y chromosome remains understudied. It is important to investigate variation on the Y chromosome to understand its evolution and contribution to phenotypic variation, including infertility. Approximately 20% of the human Y chromosome consists of ampliconi...

journal_title：Genome biology and evolution

authors： Ye D,Zaidi AA,Tomaszkiewicz M,Anthony K,Liebowitz C,DeGiorgio M,Shriver MD,Makova KD

更新日期：2018-05-01 00:00:00

abstract：:Bacteriophage flux can cause the majority of genetic diversity in free-living bacteria. This tenet of bacterial genome evolution generally does not extend to obligate intracellular bacteria owing to their reduced contact with other microbes and a predominance of gene deletion over gene transfer. However, recent studie...

journal_title：Genome biology and evolution

authors： Kent BN,Salichos L,Gibbons JG,Rokas A,Newton IL,Clark ME,Bordenstein SR

更新日期：2011-01-01 00:00:00

abstract：:Dosage compensation--equalizing gene expression levels in response to differences in gene dose or copy number--is classically considered to play a critical role in the evolution of heteromorphic sex chromosomes. As the X and Y diverge through degradation and gene loss on the Y (or the W in female-heterogametic ZW taxa...

journal_title：Genome biology and evolution

authors： Walters JR,Hardcastle TJ

更新日期：2011-01-01 00:00:00

abstract：:Evolutionary retention of duplicated genes encoding transcription-associated proteins (TAPs, comprising transcription factors and other transcriptional regulators) has been hypothesized to be positively correlated with increasing morphological complexity and paleopolyploidizations, especially within the plant kingdom....

journal_title：Genome biology and evolution

authors： Lang D,Weiche B,Timmerhaus G,Richardt S,Riaño-Pachón DM,Corrêa LG,Reski R,Mueller-Roeber B,Rensing SA

更新日期：2010-07-19 00:00:00

abstract：:Primary metabolism is essential to plants for growth and development, and secondary metabolism helps plants to interact with the environment. Many plant metabolites are industrially important. These metabolites are produced by plants through complex metabolic pathways. Lack of knowledge about these pathways is hinderi...

journal_title：Genome biology and evolution

authors： Mukherjee D,Mukherjee A,Ghosh TC

更新日期：2015-11-10 00:00:00

abstract：:Olfactory receptors (ORs) are membrane proteins that mediate the detection of odorants in the environment, and are the largest vertebrate gene family. Comparative studies of mammalian genomes indicate that OR repertoires vary widely, even between closely related lineages, as a consequence of frequent OR gains and loss...

journal_title：Genome biology and evolution

authors： Vandewege MW,Mangum SF,Gabaldón T,Castoe TA,Ray DA,Hoffmann FG

更新日期：2016-02-09 00:00:00

abstract：:Mitochondrial interactions with the nuclear genome represent one of life's most important co-evolved mutualisms. In many organisms, mitochondria are maternally inherited, and in these cases, co-transmission between the mitochondrial and nuclear genes differs across different parts of the nuclear genome, with genes on ...

journal_title：Genome biology and evolution

authors： Dean R,Zimmer F,Mank JE

更新日期：2014-05-01 00:00:00

abstract：:Constitutive defense mechanisms are critical to the understanding of defense mechanisms in conifers because they constitute the first barrier to attacks by insect pests. In interior spruce, trees that are putatively resistant and susceptible to attacks by white pine weevil (Pissodes strobi) typically exhibit constitut...

journal_title：Genome biology and evolution

authors： Verne S,Jaquish B,White R,Ritland C,Ritland K

更新日期：2011-01-01 00:00:00

abstract：:The evolution of heterogametic sex chromosomes is often-but not always-accompanied by the evolution of dosage compensating mechanisms that mitigate the impact of sex-specific gene dosage on levels of gene expression. One emerging view of this process is that such mechanisms may only evolve in male-heterogametic (XY) s...

journal_title：Genome biology and evolution

authors： Walters JR,Hardcastle TJ,Jiggins CD

更新日期：2015-09-02 00:00:00

abstract：:Multicopy ampliconic gene families on the Y chromosome play an important role in spermatogenesis. Thus, studying their genetic variation in endangered great ape species is critical. We estimated the sizes (copy number) of nine Y ampliconic gene families in population samples of chimpanzee, bonobo, and orangutan with d...

journal_title：Genome biology and evolution

authors： Vegesna R,Tomaszkiewicz M,Ryder OA,Campos-Sánchez R,Medvedev P,DeGiorgio M,Makova KD

更新日期：2020-06-01 00:00:00

abstract：:Members from Colletotrichum genus adopt a diverse range of lifestyles during infection of plants and represent a group of agriculturally devastating pathogens. In this study, we present the draft genome of Colletotrichum incanum from the spaethianum clade of Colletotrichum and the comparative analyses with five other ...

journal_title：Genome biology and evolution

authors： Gan P,Narusaka M,Kumakura N,Tsushima A,Takano Y,Narusaka Y,Shirasu K

更新日期：2016-05-22 00:00:00

abstract：:Hantaviruses are zoonotic viruses with a complex evolutionary history of virus-host coevolution and cross-species transmission. Although hantaviruses have a broad reservoir host range, virus-host relationships were previously thought to be strict, with a single virus species infecting a single host species. Here, we d...

journal_title：Genome biology and evolution

authors： Laenen L,Vergote V,Kafetzopoulou LE,Wawina TB,Vassou D,Cook JA,Hugot JP,Deboutte W,Kang HJ,Witkowski PT,Köppen-Rung P,Krüger DH,Licková M,Stang A,Striešková L,Szemeš T,Markowski J,Hejduk J,Kafetzopoulos D,Van Ranst

更新日期：2018-01-01 00:00:00

abstract：:Bacteria can evolve rapidly under positive selection owing to their vast numbers, allowing their genes to diversify by adapting to different environments. We asked whether the same genes that evolve rapidly in the long-term evolution experiment (LTEE) with Escherichia coli have also diversified extensively in nature. ...

journal_title：Genome biology and evolution

authors： Maddamsetti R,Hatcher PJ,Green AG,Williams BL,Marks DS,Lenski RE

更新日期：2017-04-01 00:00:00

abstract：:All living organisms require protein degradation to terminate biological processes and remove damaged proteins. One such machine is the 20S proteasome, a specialized barrel-shaped and compartmentalized multicatalytic protease. The activity of the 20S proteasome generally requires the binding of regulators/proteasome a...

journal_title：Genome biology and evolution

authors： Fort P,Kajava AV,Delsuc F,Coux O

更新日期：2015-05-04 00:00:00

abstract：:The phylum Apicomplexa is a quintessentially parasitic lineage, whose members infect a broad range of animals. One exception to this may be the apicomplexan genus Nephromyces, which has been described as having a mutualistic relationship with its host. Here we analyze transcriptome data from Nephromyces and its parasi...

journal_title：Genome biology and evolution

authors： Paight C,Slamovits CH,Saffo MB,Lane CE

更新日期：2019-01-01 00:00:00

abstract：:Perennial ryegrass (Lolium perenne L.) is widely used for forage production in both permanent and temporary grassland systems. To increase yields in perennial ryegrass, recent breeding efforts have been focused on strategies to more efficiently exploit heterosis by hybrid breeding. Cytoplasmic male sterility (CMS) is ...

journal_title：Genome biology and evolution

authors： Sykes T,Yates S,Nagy I,Asp T,Small I,Studer B

更新日期：2017-02-01 00:00:00

abstract：:A major mode of gene expression evolution is based on changes in cis-regulatory elements (CREs) whose function critically depends on the presence of transcription factor-binding sites (TFBS). Because CREs experience extensive TFBS turnover even with conserved function, alignment-based studies of CRE sequence evolution...

journal_title：Genome biology and evolution

authors： Otto W,Stadler PF,López-Giraldéz F,Townsend JP,Lynch VJ,Wagner GP

更新日期：2009-05-25 00:00:00

abstract：:RNA editing occurs in the organellar mRNAs of all land plants but the marchantioid liverworts, making liverworts a perfect group for studying the evolution of RNA editing. Here, we profiled the RNA editing of 42 exemplars spanning the ordinal phylogenetic diversity of liverworts, and screened for the nuclear-encoded p...

journal_title：Genome biology and evolution

authors： Dong S,Zhao C,Zhang S,Wu H,Mu W,Wei T,Li N,Wan T,Liu H,Cui J,Zhu R,Goffinet B,Liu Y

更新日期：2019-11-01 00:00:00

abstract：:Fish use olfaction to sense a variety of nonvolatile chemical signals in water. However, the evolutionary importance of olfaction in species-rich cichlids is controversial. Here, we determined an almost complete sequence of the vomeronasal type 2 receptor-like (OlfC: putative amino acids receptor in teleosts) gene clu...

journal_title：Genome biology and evolution

authors： Nikaido M,Suzuki H,Toyoda A,Fujiyama A,Hagino-Yamagishi K,Kocher TD,Carleton K,Okada N

更新日期：2013-01-01 00:00:00

abstract：:It has been estimated that the sister plant pathogenic fungal species Heterobasidion irregulare and Heterobasidion annosum may have been allopatrically isolated for 34-41 Myr. They are now sympatric due to the introduction of the first species from North America into Italy, where they freely hybridize. We used a compa...

journal_title：Genome biology and evolution

authors： Sillo F,Garbelotto M,Friedman M,Gonthier P

更新日期：2015-11-01 00:00:00

abstract：:Only few studies on snake venoms were dedicated to deeply characterize the toxin secretion of animals from the Colubridae family, despite the fact that they represent the majority of snake diversity. As a consequence, some evolutionary trends observed in venom proteins that underpinned the evolutionary histories of sn...

journal_title：Genome biology and evolution

authors： Campos PF,Andrade-Silva D,Zelanis A,Paes Leme AF,Rocha MM,Menezes MC,Serrano SM,Junqueira-de-Azevedo Ide L

更新日期：2016-08-16 00:00:00

abstract：:Vomeronasal sensitivity is important for detecting intraspecific pheromonal cues as well as environmental odorants and is involved in mating, social interaction, and other daily activities of many vertebrates. Two large families of seven-transmembrane G-protein-coupled receptors, V1rs and V2rs, bind to various ligands...

journal_title：Genome biology and evolution

authors： Park SH,Podlaha O,Grus WE,Zhang J

更新日期：2011-01-01 00:00:00