Abstract:
RATIONALE AND OBJECTIVES:Obscure gastrointestinal bleeding (OGIB) is the bleeding from the gastrointestinal tract without definite source that persists and recurs after a negative endoscopic evaluation. The study aimed to systematically evaluate the diagnostic accuracy of computed tomography enterography on OGIB detection by meta-analysis. MATERIALS AND METHODS:Studies were searched in relevant databases. With predefined inclusion criteria, eligible studies were included, followed by quality assessment using the Quality Assessment of Diagnostic Accuracy Studies scoring system. The Meta-DiSc software was used to implement the meta-analysis, and sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, and diagnostic odds ratio with their 95% confidence intervals (CIs) were used as the effect size. Publication bias was determined by Egger test. RESULTS:A set of nine studies was included in this meta-analysis, having a relatively high quality. Under the random effects model, the pooled sensitivity and specificity were 0.724 (95% CI: 0.651-0.789) and 0.752 (95% CI: 0.691-0.807), respectively. Under the fixed effects model, the pooled positive likelihood ratio, negative likelihood ratio, and diagnostic odds ratio were 2.949 (95% CI: 2.259-3.850), 0.393 (95% CI: 0.310-0.497), and 9.452 (95% CI: 5.693-15.692), respectively. The area under curve of the summary receiver operating characteristic curve was 0.7916 (95% CI: 0.723-0.860). No obvious publication bias was detected (t = 1.62, P = .181). CONCLUSIONS:Computed tomography enterography might be used as a complementary to video capsule endoscopy instead of an alternative for the detection of OGIB.
journal_name
Acad Radioljournal_title
Academic radiologyauthors
He B,Yang J,Xiao J,Gu J,Chen F,Wang L,Qian J,Gong Sdoi
10.1016/j.acra.2017.09.001subject
Has Abstractpub_date
2018-02-01 00:00:00pages
196-201issue
2eissn
1076-6332issn
1878-4046pii
S1076-6332(17)30366-5journal_volume
25pub_type
杂志文章,meta分析,评审abstract:RATIONALE AND OBJECTIVES:Lymphangiomatosis is a rare disease characterized by the widespread presence of lymphangiomas in any part of the body. In previous studies, lymphatic vessel abnormalities in lymphangiomatosis have only rarely been mentioned. The objective of this paper is to discuss the imaging features of lymp...
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pub_type: 杂志文章,多中心研究
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journal_title:Academic radiology
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pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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