Abstract：
:The present study deals with the evaluation of antidiabetic activities of Fagioli di Sarconi beans (Phaseolus vulgaris), including 21 ecotypes protected by the European Union with the mark PGI (i.e., Protected Geographical Indication), and cultivated in Basilicata (southern Italy). For this purpose, α-glucosidase and α-amylase assays were assessed; among all bean ecotypes, the tight green seed colour of Verdolino extracts exhibited the highest α-glucosidase and α-amylase inhibitory activity with IC50=1.1±0.1μg/ml and IC50=19.3±1.1μg/ml, respectively. Phytochemical compound screening of all Fagioli di Sarconi beans performed by flow injection-electrospray ionization-ultrahigh resolution mass spectrometry (uHRMS) and based on the calculation of elemental formulas from accurate m/z values, was helpful to annotate specific compounds, such as alkaloids, saponins, flavonoids, and terpenoids, which are most likely responsible for their biological activity.
journal_name
Food Chemjournal_title
Food chemistryauthors
Pascale R,Bianco G,Cataldi TRI,Kopplin PS,Bosco F,Vignola L,Uhl J,Lucio M,Milella Ldoi
10.1016/j.foodchem.2017.09.091subject
Has Abstractpub_date
2018-03-01 00:00:00pages
497-504eissn
0308-8146issn
1873-7072pii
S0308-8146(17)31566-2journal_volume
242pub_type
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