Abstract：
:A large number of bioactive peptides isolated from natural sources are known to play important physiological roles in the human body. It is possible to use these as alternative therapy agents. One example is yolkin which can be useful as a food supplement, a natural therapeutic agent for preventing and treating cognitive disorders of various origins, preferably in patients with unsatisfactory responses to known therapies. A new simple method of isolation of yolkin based on precipitation with ethanol or acetone was developed. The best precipitation efficiency of both ethanol and acetone was achieved when stirred into the starting material to a final concentration of 70%. These methods preserved the ability of yolkin to stimulate human whole blood cells to release anti-inflammatory cytokines and neurotrophins. At first we indicated that yolkin displayed a potential neuroprotective effect by the ability to stimulate cells to produce pro-survival brain derived neurotrophic factor (BDNF).
journal_name
Food Chemjournal_title
Food chemistryauthors
Zambrowicz A,Zabłocka A,Bobak Ł,Macała J,Janusz M,Polanowski A,Trziszka Tdoi
10.1016/j.foodchem.2017.03.101subject
Has Abstractpub_date
2017-09-01 00:00:00pages
705-711eissn
0308-8146issn
1873-7072pii
S0308-8146(17)30482-Xjournal_volume
230pub_type
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