Remnant lymph node metastases after neoadjuvant therapy and surgery in patients with pathologic T0 esophageal carcinoma impact on prognosis: A systematic review and meta-analysis.

Abstract:

BACKGROUND:The aim of this study was to evaluate the outcomes of patients with pathologic T0 esophageal carcinoma after neoadjuvant therapy and surgery. METHODS:We searched PubMed, Embase, Cochrane Library, and Medline databases from inception up to November 12, 2016. The meta-analysis was performed to compare odds ratios (OR) for overall survival (OS), disease-free survival (DFS), local control (LC), and distant control (DC). RESULTS:Eight published studies of 837 patients were included in the meta-analysis. Data showed that the ypT0N1 group was associated with worse outcomes compared with the ypT0N0 group. The pooled OR and 95% confidence interval (CI) for 3-year and 5-year OS were 3.08 [2.07, 4.57] and 4.27 [2.76, 6.59], respectively. Whereas, the pooled OR and 95% CI for 3-year and 5-year DFS were 3.90 [2.08, 7.34] and 5.17 [1.93, 13.87], respectively. The pooled OR and 95% CI for LR and DR were 4.52 [1.72, 11.91] and 2.65 [1.38, 5.09], respectively. CONCLUSIONS:Remnant lymph node metastases after neoadjuvant therapy and surgery in patients with pathologic T0 esophageal carcinoma portend poor survival, and it is an important prognostic factor.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Lv HW,Li Y,Zhou MH,Cheng JW,Xing WQ

doi

10.1097/MD.0000000000007342

subject

Has Abstract

pub_date

2017-06-01 00:00:00

pages

e7342

issue

26

eissn

0025-7974

issn

1536-5964

pii

00005792-201706300-00058

journal_volume

96

pub_type

杂志文章,meta分析,评审

相关文献

MEDICINE文献大全
  • The poor prognosis of the primary gastric epithelioid angiosarcoma: A case report.

    abstract:RATIONALE:Primary gastric epithelioid angiosarcoma is a highly aggressive endothelial cell malignancy and may pose a great diagnostic challenge. PATIENT CONCERNS:Here we describe the case of a 56-year-old man presented with melena and epigastric dull pain for 2 weeks. DIAGNOSIS:Primary gastric epithelioid angiosarcom...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010287

    authors: Xia J,Shi D,Wu Z,Chen Y,Liu B,Chen L,Metta W,Zheng Y

    更新日期:2018-04-01 00:00:00

  • Intralesional and subcutaneous application of Viscum album L. (European mistletoe) extract in cervical carcinoma in situ: A CARE compliant case report.

    abstract:RATIONALE:Carcinoma in situ (CIS) of the uterine cervix is a premalignant condition of squamous epithelium. The standard treatments are excision and ablation procedures; for women with positive margins, hysterectomy is recommended. PATIENT CONCERNS:A 47-year-old Peruvian woman with recurrent candidal vaginitis had bee...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000013420

    authors: Reynel M,Villegas Y,Kiene H,Werthmann PG,Kienle GS

    更新日期:2018-11-01 00:00:00

  • Effects of oxymatrine on the proliferation of human liver cancer Bel-7404 cells: A protocol of systematic review and meta-analysis.

    abstract:BACKGROUND:This study will examine the effects of oxymatrine on the proliferation of human liver cancer Bel-7404 cells (HLCBC). METHODS:This study will search electronic bibliographic databases available in PUBMED, EMBASE, Cochrane Library, Scopus, Cumulative Index to Nursing and Allied Health Literature, China Biolog...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000020181

    authors: Li J,Liu ZY,Yu HB,Xue Q,Qu XS

    更新日期:2020-06-05 00:00:00

  • Takotsubo cardiomyopathy caused by acute respiratory stress from extubation: A case report.

    abstract:RATIONAL:Takotsubo cardiomyopathy (TCM) is a transient systolic dysfunction of the left ventricular apex without stenosis of coronary arteries and is induced by various psychological and physical factors. TCM sometimes causes lethal complications such as arrhythmia, thrombogenesis, and even cardiac rupture, and thus it...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000008946

    authors: Taniguchi K,Takashima S,Iida R,Ota K,Nitta M,Sakane K,Fujisaka T,Ishizaka N,Umegaki O,Uchiyama K,Takasu A

    更新日期:2017-12-01 00:00:00

  • High plasma fibrinogen is correlated with poor response to trastuzumab treatment in HER2 positive breast cancer.

    abstract::Some of HER-2 positive breast cancer patients failed to trastuzumab treatment. Recent reports have indicated the correlation between plasma coagulation parameters and clinical characteristics in breast cancer. The aim of this study was to analyze the role of coagulation parameters in trastuzumab treated patients. Coag...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000000481

    authors: Liu YL,Lu Q,Liang JW,Xia Y,Zhang W,Hu BQ,Shang FF,Ji YR,Wang J,Wang Q,Liang B

    更新日期:2015-02-01 00:00:00

  • Recurrent spontaneous hepatic rupture in pregnancy: A case report.

    abstract:RATIONALE:Spontaneous and repeated hepatic ruptures caused by hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome are uncommon but life-threatening conditions that rarely occur early in the second trimester of pregnancy. PATIENT CONCERNS:We describe a patient who experienced spontaneous hepatic ruptu...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000011458

    authors: Han GH,Kim MA

    更新日期:2018-07-01 00:00:00

  • Smoking and incidence of glaucoma: The SUN Cohort.

    abstract::Smoking is a serious global public health concern that has been related to many chronic diseases. However, the effect of smoking on eye disorders has been less studied. The aim of this cohort study was to assess the association between current tobacco smokers and the risk of developing glaucoma and furthermore to eval...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005761

    authors: Pérez-de-Arcelus M,Toledo E,Martínez-González MÁ,Martín-Calvo N,Fernández-Montero A,Moreno-Montañés J

    更新日期:2017-01-01 00:00:00

  • Successful superselective embolization with n-butyl cyanoacrylate for hemorrhage from superficial femoral artery branches following blunt trauma: Three case reports.

    abstract:INTRODUCTION:In blunt traumatic superficial femoral arterial (SFA) injuries, hemorrhage from the branches without injury to the main artery is rare, but can lead to serious complications, such as compartment syndrome affecting the clinical outcomes. Although open surgical repair has been the standard approach to periph...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000020467

    authors: Oh CH,Kim Y,Lee JH,Kim HR,Go SJ

    更新日期:2020-07-02 00:00:00

  • Prognostic significance of cardiac troponin I levels in hospitalized patients presenting with supraventricular tachycardia.

    abstract::Although cardiac troponin I (cTnI) elevation in patients presenting to the hospital with supraventricular tachycardia (SVT) is well recognized, the prevalence, predictors, and prognostic significance of cTnI elevation associated with SVT presentation are not known. We screened records of all patients presenting to 2 h...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0b013e3181dddb3b

    authors: Chow GV,Hirsch GA,Spragg DD,Cai JX,Cheng A,Ziegelstein RC,Marine JE

    更新日期:2010-05-01 00:00:00

  • Early severe coronary heart disease and ischemic heart failure in homozygous familial hypercholesterolemia: A case report.

    abstract:RATIONALE:Familial hypercholesterolemia (FH) is a common inherited cause of coronary heart disease (CHD) and premature death in an early age. Nevertheless, an ischemic heart failure (IHF) associated with FH seems to be rare, and an early diagnosis and therapy could influence the prognosis. PATIENT CONCERNS:In this 13-...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012869

    authors: Kuang H,Zhou X,Li L,Yi Q,Shou W,Lu T

    更新日期:2018-10-01 00:00:00

  • Calcified peripancreatic lymph nodes in pancreatic and hepatic tuberculosis mimicking pancreatic malignancy: A case report and review of literature.

    abstract:RATIONALE:Tuberculosis remains a serious menace to the health of people. Isolated hepatic tuberculosis is rare and pancreatic tuberculosis is extremely rare. The preoperative diagnosis of pancreatic tuberculosis remains a great challenge. PATIENT CONCERNS:A 58-year-old Asian woman was referred to our hospital for eval...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000012255

    authors: Liang X,Huang X,Yang Q,He J

    更新日期:2018-09-01 00:00:00

  • Efficacy of risk stratification protocols and clinical, physical, and biochemical parameters to previse signals and symptoms during cardiovascular rehabilitation programs: Protocol for an observational trial.

    abstract:INTRODUCTION:Despite the benefits, cardiovascular rehabilitation programs (CRPs) have been related to the appearance of signals and symptoms. Risk stratification protocols are commonly used to identify risks during the physical exercise; however, studies that investigate their efficacy to previse signals and symptoms a...

    journal_title:Medicine

    pub_type: 临床试验,杂志文章

    doi:10.1097/MD.0000000000015700

    authors: Vanzella LM,Takahashi C,Ribeiro F,Lima IM,Silva AKFD,Christófaro DGD,Vanderlei LCM

    更新日期:2019-06-01 00:00:00

  • Fractional curve progression with maintenance of fusion mass in congenital scoliosis: An 18-year follow-up of a case report.

    abstract:RATIONALE:The management of congenital scoliosis concentrates on early diagnosis and proper surgical treatment before the development of severe deformities. Decision making regarding the appropriate fusion levels, proper surgical treatment, and reduction amount of kyphoscoliosis is very important but difficult in the t...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000007746

    authors: Chang DG,Yang JH,Suk SI,Suh SW,Kim JH,Lee SJ,Na KH,Lee JH

    更新日期:2017-09-01 00:00:00

  • Pretreatment elevated serum lactate dehydrogenase as a significant prognostic factor in malignant mesothelioma: A meta-analysis.

    abstract:BACKGROUND:Lactate dehydrogenase (LDH) as a hypoxia-regulator plays a vital role in alternative metabolic pathways of cancer cells. Numerous studies have assessed the prognostic value of elevated pretreatment LDH in malignant mesothelioma (MM). However, the results have been largely inconsistent. Hence, the aim of curr...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000005706

    authors: Zhuo Y,Lin L,Wei S,Zhang M

    更新日期:2016-12-01 00:00:00

  • Goniosynechialysis combined with cataract extraction for iridoschisis: A case report.

    abstract:RATIONALE:Iridoschisis is a rare eye disease. In this case report, we described the examination and diagnosis of a case of iridoschisis accompanied by secondary glaucoma. We also observed the effects of treating the patient with a combination of goniosynechialysis and cataract removal. PATIENT CONCERN:A 67-year-old fe...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000008295

    authors: You Z,Qin Y,Li G,Shi K

    更新日期:2017-10-01 00:00:00

  • A clinical prediction rule for acute bilirubin encephalopathy in neonates with extreme hyperbilirubinemia: A retrospective cohort study.

    abstract::To establish a clinical prediction rule for acute bilirubin encephalopathy (ABE) in term/near-term neonates with extreme hyperbilirubinemia.A retrospective cohort study was conducted between January 2015 and December 2018. Six hundred seventy-three out of 26,369 consecutive neonates with extreme hyperbilirubinemia wer...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019364

    authors: Zhang F,Chen L,Shang S,Jiang K

    更新日期:2020-02-01 00:00:00

  • Increased APRIL Expression Induces IgA1 Aberrant Glycosylation in IgA Nephropathy.

    abstract::Aberrant glycosylated IgA1 molecules, mainly galactose-deficient IgA1 (Gd-IgA1), are important causal factors in IgA nephropathy; however, the underlying mechanism for the production of aberrantly glycosylated IgA1 is unknown. A recent genome-wide association study identified a novel IgAN susceptibility gene, TNFSF13,...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000003099

    authors: Zhai YL,Zhu L,Shi SF,Liu LJ,Lv JC,Zhang H

    更新日期:2016-03-01 00:00:00

  • The effectiveness of complementary manual therapies for pregnancy-related back and pelvic pain: A systematic review with meta-analysis.

    abstract:BACKGROUND:Low back pain and pelvic girth pain are common in pregnancy and women commonly utilize complementary manual therapies such as massage, spinal manipulation, chiropractic, and osteopathy to manage their symptoms. OBJECTIVE:The aim of this systematically review was to critically appraise and synthesize the bes...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000004723

    authors: Hall H,Cramer H,Sundberg T,Ward L,Adams J,Moore C,Sibbritt D,Lauche R

    更新日期:2016-09-01 00:00:00

  • Erratum: False positive 18FDG PET-CT results due to exogenous lipoid pneumonia secondary to oily drug inhalation: A case report: Erratum.

    abstract::[This corrects the article DOI: 10.1097/MD.0000000000006889.]. ...

    journal_title:Medicine

    pub_type: 已发布勘误

    doi:10.1097/MD.0000000000007315

    authors:

    更新日期:2017-06-16 00:00:00

  • Clinicopathological features, surgical treatments, and survival outcomes of patients with small bowel adenocarcinoma.

    abstract::To date, because of their rarity, the clinicopathological features and surgical outcomes of small bowel adenocarcinomas (SBAs) have been insufficiently explored. We evaluated the clinicopathological features and long-term outcomes of patients who underwent surgery for SBA.This retrospective study (from 1999 to 2016) e...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000007713

    authors: Zhang S,Yuan W,Zhang J,Chen Y,Zheng C,Ma J,Jiang Q,Zhao Y,Xu Q,Wang C

    更新日期:2017-08-01 00:00:00

  • Musculoskeletal ultrasound-guided physical therapy in hemiplegic shoulder pain: A CARE-compliant case report.

    abstract:RATIONALE:The use of musculoskeletal ultrasound (MU) method in the diagnosis of shoulder pain and injury and guidance of injection and pain blocking has been established. However, the treatment of posthemiplegic shoulder pain (HSP) with MU-guided precise physical therapy has not been reported. PATIENT CONCERNS:Here, w...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000009188

    authors: Zhang J,Li Y,Wang H

    更新日期:2017-12-01 00:00:00

  • Purulent pericarditis: report of 2 cases and review of the literature.

    abstract::Purulent pericarditis, a localized infection within the pericardial space, has become a rare entity in the modern antibiotic era. Although historically a disease of children and young adults, this is no longer the case: the median age at the time of diagnosis has increased by nearly 30 years over the past 6 decades. D...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0b013e318194432b

    authors: Parikh SV,Memon N,Echols M,Shah J,McGuire DK,Keeley EC

    更新日期:2009-01-01 00:00:00

  • Rhabdomyolysis associated with single-dose intravenous esomeprazole administration: A case report.

    abstract:BACKGROUND:Proton pump inhibitors are usually safe, although serious adverse effects can occur. We report the first case of rhabdomyolysis associated with single-dose intravenous esomeprozole administration. METHODS:A 45-year-old Korean male visited our emergency room because of persistent lower chest discomfort that ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000004313

    authors: Jeon DH,Kim Y,Kim MJ,Cho HS,Bae EJ,Chang SH,Park DJ

    更新日期:2016-07-01 00:00:00

  • Lymphodepletion chemotherapy revitalizes chimeric antigen receptor T cells contributing to regression of relapsed B-cell lymphoma: A case report.

    abstract:INTRODUCTION:Chimeric antigen receptor T cells (CAR-T) targeting CD19 have shown great potential for treatment of B-cell malignancies. For those patients who can not achieve complete remission (CR) or suffer from relapse after CAR-T therapy, further therapeutic strategies still remain elusive. Whether existing CAR-T ce...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000022510

    authors: Liang Z,Zhang H,Shao M,Cui Q,Wu Z,Xiao L,Huang H,Hu Y

    更新日期:2020-10-23 00:00:00

  • Exploring prognostic genes in ovarian cancer stage-related coexpression network modules.

    abstract::Identification of meaningful cluster modules of differential genes or representative biomarkers related to the stages of ovarian cancer (OC) is pivotal, which may help to detect mechanisms of OC progression and evaluate OC patients' prognosis.We downloaded gene expression data and the corresponding clinical informatio...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000011895

    authors: Yang L,Jing J,Sun L,Yue Y

    更新日期:2018-08-01 00:00:00

  • Inflammation-based Glasgow Prognostic Score in patients with acute ST-segment elevation myocardial infarction: A prospective cohort study.

    abstract::The inflammation-based Glasgow Prognostic Score (GPS), which involves C-reactive protein and serum albumin levels, has been reported to be a strong independent predictor of mortality in many cancers. This study aimed to investigate whether the GPS is associated with mortality in patients with acute ST-segment elevatio...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000013615

    authors: Jia Y,Li D,Cao Y,Cheng Y,Xiao L,Gao Y,Zhang L,Zeng Z,Wan Z,Zeng R

    更新日期:2018-12-01 00:00:00

  • Intravoxel incoherent motion diffusion-weighted imaging evaluated the response to concurrent chemoradiotherapy in patients with cervical cancer.

    abstract::To evaluate the application of multiple b values diffusion-weighted imaging based on biexponential signal decay model to predict the response to concurrent chemoradiotherapy in cervical cancer patients.This prospective study enrolled 28 patients (mean age: 50.89 ± 10.70 years) with cervical cancer confirmed by biopsy ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000017943

    authors: Bian H,Liu F,Chen S,Li G,Song Y,Sun M,Dong H

    更新日期:2019-11-01 00:00:00

  • Endometrial cancer and antidepressants: A nationwide population-based study.

    abstract::To our knowledge, the association between antidepressant exposure and endometrial cancer has not been previously explored. Herein, we aim to investigate the association between antidepressant prescription, including novel antidepressants, and the risk for endometrial cancer in a population-based study.Data for the ana...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000004178

    authors: Lin CF,Chan HL,Hsieh YH,Liang HY,Chiu WC,Huang KY,Lee Y,McIntyre RS,Chen VC

    更新日期:2016-07-01 00:00:00

  • Circulating D-dimer level correlates with disease characteristics in hepatoblastoma patients.

    abstract:OBJECTIVES:Hepatoblastoma (HB) is the most common pediatric liver malignancy, typically affecting children within the first 4 years of life. However, only a few validated blood biomarkers are used in clinical evaluation. The current study explored the clinical application and significance of D-dimer levels in patients ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000008798

    authors: Zhang B,Liu G,Liu X,Zheng S,Dong K,Dong R

    更新日期:2017-11-01 00:00:00

  • Diastolic dysfunction is associated with an increased risk of postcontrast acute kidney injury.

    abstract:STUDY OBJECTIVE:Computed tomography (CT) is an important imaging modality in diagnosing a variety of disorders. Although systolic heart failure is a well-known risk factor for postcontrast acute kidney injury (PC-AKI), few studies have evaluated the association between diastolic dysfunction and PC-AKI. Therefore, the a...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000017994

    authors: Lee MJ,Park JS,Kim HH

    更新日期:2019-11-01 00:00:00