Intralesional and subcutaneous application of Viscum album L. (European mistletoe) extract in cervical carcinoma in situ: A CARE compliant case report.

Abstract:

RATIONALE:Carcinoma in situ (CIS) of the uterine cervix is a premalignant condition of squamous epithelium. The standard treatments are excision and ablation procedures; for women with positive margins, hysterectomy is recommended. PATIENT CONCERNS:A 47-year-old Peruvian woman with recurrent candidal vaginitis had been diagnosed with colpocervicitis and squamous metaplasia 8 years ago, which were not treated. DIAGNOSES:The patient was diagnosed with CIS after cervical conization procedure. She refused radical hysterectomy and opted for integrative medicine treatment. INTERVENTIONS:She was treated with intralesional and subcutaneous Viscum album L. extract (VAE) injections. VAE is a widely used herbal cancer treatment with cytotoxic, apoptogenic, and immunological effects, but it has not been investigated in cervical CIS. OUTCOMES:Ending month 5 of treatment, complete remission of cervical CIS was observed. The patient is still in remission after 30 months (until publication). LESSONS:This is the first report on complete remission of cervical CIS after intralesional and subcutaneous injection with VAE. Prospective studies should evaluate to what degree the treatment effect is reproducible.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Reynel M,Villegas Y,Kiene H,Werthmann PG,Kienle GS

doi

10.1097/MD.0000000000013420

subject

Has Abstract

pub_date

2018-11-01 00:00:00

pages

e13420

issue

48

eissn

0025-7974

issn

1536-5964

pii

00005792-201811300-00070

journal_volume

97

pub_type

杂志文章

相关文献

MEDICINE文献大全
  • Geographic coverage of male circumcision in western Kenya.

    abstract::Voluntary Medical Male Circumcision (VMMC) for human immunodeficiency virus (HIV) prevention has scaled up rapidly among young men in western Kenya since 2008. Whether the program has successfully reached uncircumcised men evenly across the region is largely unknown. Using data from two cluster randomized surveys from...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005885

    authors: Akullian A,Onyango M,Klein D,Odhiambo J,Bershteyn A

    更新日期:2017-01-01 00:00:00

  • PET-CT for Evaluation of Spleen and Liver 18F-FDG Diffuse Uptake Without Lymph Node Enlargement in Lymphoma.

    abstract::The aim of the study was to compare differences between lymphoma and inflammation as indicated by high diffuse uptake of F-fluorodeoxyglucose (F-FDG) in the spleen, liver, and bone marrow without increased F-FDG uptake in the lymph nodes and without enlarged peripheral lymph nodes.Eighteen lymphoma patients and 14 inf...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000003750

    authors: Rao L,Wang X,Zong Z,Chen Z,Shi X,Yi C,Zhang X,Yang Z

    更新日期:2016-05-01 00:00:00

  • No associations exists between red blood cell distribution width and serum uric acid in both sexes.

    abstract::The aim of this study was to determine whether there was a significant association between red blood cell distribution width (RDW) and uric acid (UA) in a large Chinese population.This was a cross-sectional study with an enrollment of 80,298 ostensibly healthy participants (48,971 males, 31,327 females) during the per...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012707

    authors: Zhang C,Meng Z,Li X,Liu M,Ren X,Zhu M,He Q,Zhang Q,Song K,Jia Q,Chen Q

    更新日期:2018-10-01 00:00:00

  • The spectrum of invasive pneumococcal disease at an adult tertiary care hospital in the early 21st century.

    abstract::Despite widespread pneumococcal vaccination of children and adults, invasive pneumococcal disease (IPD) remains prominent. Using our database of all Streptococcus pneumoniae infections at the Veterans Affairs Medical Center, Houston, Texas, since 2000, we reviewed cases of IPD, defined as the isolation of pneumococci ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0b013e3181f2b824

    authors: Rueda AM,Serpa JA,Matloobi M,Mushtaq M,Musher DM

    更新日期:2010-09-01 00:00:00

  • Point prevalence and epidemiological characteristics of chronic cough in the general adult population: The Korean National Health and Nutrition Examination Survey 2010-2012.

    abstract::Cough is frequently self-limiting, but may persist longer in certain individuals. Most of previous studies on the epidemiology of chronic cough have only measured period prevalence, and thus have afforded limited information on the burden and natural course. We aimed to investigate the epidemiology of chronic cough by...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000006486

    authors: Kang MG,Song WJ,Kim HJ,Won HK,Sohn KH,Kang SY,Jo EJ,Kim MH,Kim SH,Kim SH,Park HW,Chang YS,Lee BJ,Morice AH,Cho SH

    更新日期:2017-03-01 00:00:00

  • Cross-sectional evaluation of the interaction between activity relative-time expenditure and comorbidity concerning physical quality of life.

    abstract::Quality of life (QoL) is a matter of concern in both healthy and diseased individuals. Lifestyle factors such as physical activity and sleep have a direct impact on QoL. In this context, interactions between activity time expenditure and QoL might be different in comorbid and non comorbid patients. Besides, the quanti...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000022552

    authors: Suarez-Villar R,Martinez-Urbistondo D,Fernandez MA,Lopez-Cano M,Fernandez E,Dominguez A,Prosper L,Rodriguez-Cobo A,Tinoco MEC,Nadal P,Risco CR,Fernández PV,Martínez JA

    更新日期:2020-11-25 00:00:00

  • Primary intracranial leiomyosarcoma in an immunocompetent patient: Case report with emphasis on imaging features.

    abstract:RATIONALE:Primary intracranial leiomyosarcoma (LMS) is an extremely rare tumor in the central nervous system (CNS), and usually seen in immunocompromised individuals. Only a few cases of primary intracranial LMS have been documented in the literature and no study focused on their MRI findings. We reported a case of pri...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000015269

    authors: Li XL,Ren J,Niu RN,Jiang X,Xu GH,Zhou P,Cheng ZZ

    更新日期:2019-04-01 00:00:00

  • Treatment of a patient with breast cancer and glucose 6-phosphate dehydrogenase deficiency: A case report.

    abstract:RATIONALE:Glucose 6-phosphate dehydrogenase (G6PD) deficiency is the most common enzymatic disorder of red blood cells that cause hemolytic anemia. Some anticancer drugs are reported to trigger oxidative stress; however, events of hemolysis are rarely discussed in patients with G6PD deficiency required oncologic treatm...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014987

    authors: Chung WP,Hsu YT,Chen YP,Hsu HP

    更新日期:2019-03-01 00:00:00

  • Ten-Year Changes in the Hepatitis B Prevalence in the Birth Cohorts in Korea: Results From Nationally Representative Cross-Sectional Surveys.

    abstract::To compare the prevalence of hepatitis B virus (HBV) infection over a 10-year period in terms of population-level trends, we established hypothetical birth cohorts that represented each 10-year interval age group.We used data from the Korean National Health and Nutrition Examination Surveys conducted between 1998 to 2...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000001469

    authors: Park B,Jung KW,Oh CM,Choi KS,Suh M,Jun JK

    更新日期:2015-10-01 00:00:00

  • Why recurrence was initially suspected during colorectal cancer postoperative surveillance?: A retrospective analysis.

    abstract::Routine postoperative surveillance is recommended for the patients with colorectal cancer (CRC). This study aimed to clarify the conditions indicate initial suspicion of CRC recurrence in different preoperative serum carcinoembryonic antigen (CEA) level groups, including positive physical signs/symptoms, elevated CEA ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000022803

    authors: Hung H,You J,Chiang J,Hsieh P,Chiang S,Lai C,Tasi W,Yeh C

    更新日期:2020-10-23 00:00:00

  • Successful treatment of disseminated intravascular coagulation by recombinant human soluble thrombomodulin in patients with acute myeloid leukemia.

    abstract::Disseminated intravascular coagulation (DIC) is a life-threatening condition that frequently occurs in patients with hematologic malignancies. Currently, recombinant human soluble thrombomodulin (rTM) is a therapeutic DIC drug that is manufactured and sold in Japan only. We evaluated the efficacy of rTM compared to th...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012981

    authors: Ookura M,Hosono N,Tasaki T,Oiwa K,Fujita K,Ito K,Lee S,Matsuda Y,Morita M,Tai K,Negoro E,Kishi S,Iwasaki H,Ueda T,Yamauchi T

    更新日期:2018-11-01 00:00:00

  • Paraproteinemic keratopathy in monoclonal gammopathy of undetermined significance treated with primary keratoprosthesis: Case report, histopathologic findings, and world literature review.

    abstract:RATIONALE:We report a case of paraproteinemic keratopathy associated with monoclonal gammopathy of undetermined significance, treated with keratoprosthesis as a primary penetrating procedure. Histopathological findings and a world literature review are presented. PATIENT CONCERNS:A 74 year old female recently diagnose...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000008649

    authors: Chiang HH,Wieland RS,Rogers TS,Gibson PC,Atweh G,McCormick G

    更新日期:2017-12-01 00:00:00

  • Dengzhanxixin injection for cerebral infarction: A systematic review and meta-analysis of randomized controlled trials.

    abstract:BACKGROUND:No systematic review has been published in English of Dengzhanxixin (DZXX) injection for cerebral infarction. The aim of this systematic review was to assess the effects and safety of DZXX injection for cerebral infarction. METHODS:Eight databases were searched from their inception. Randomized controlled tr...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000007674

    authors: Wang J,Xie Y,Zhao S,Zhang J,Chai Y,Li Y,Liao X

    更新日期:2017-08-01 00:00:00

  • Removal of the root canal smear layer using Carisolv III and sodium hypochlorite.

    abstract::The present study investigated the effectiveness of a Carisolv III + 0.5% sodium hypochlorite (NaOCl)-based root canal irrigant for smear layer removal.Forty maxillary incisors were randomly divided into 4 groups (n = 10 per group). The canals in group A (experimental) were prepared with 0.5% NaOCl, and Carisolv III a...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000020372

    authors: Wu D,Ma YZ,Jia J,Xin BC,Wang DS,Sun DG,Wang LX

    更新日期:2020-05-29 00:00:00

  • Efficacy of furosemide for treatment of liver cirrhosis: A systematic review protocol of randomized controlled trial.

    abstract:BACKGROUND:Previous clinical studies have reported that furosemide can be used to treat liver cirrhosis (LC) effectively. However, no study systematically explored this issue. This systematic review aims to investigate the efficacy and safety of furosemide for treatment of LC. METHODS:This study will be conducted thro...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000015300

    authors: Zhu ZR,Liu WL,Ding ZM,Li Y

    更新日期:2019-04-01 00:00:00

  • Effects of core strength training combined with Tai Chi Chuan for the musculoskeletal system and cardiopulmonary function in older adults: A study protocol for a randomized controlled trial.

    abstract:BACKGROUND:According to the national census, China has gradually become an aging society; moreover, aging has become an irreversible worldwide trend in the twenty-first century. Aging can lead to decreased physical function, mobility, cardiopulmonary function and quality of life (QOL). The feasibility and benefits of c...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0000000000012024

    authors: Jia X,Jiang C,Tao J,Li Y,Zhou Y,Chen LD

    更新日期:2018-08-01 00:00:00

  • Qishen Yiqi dripping pills for ischemic heart failure: A protocol for a prospective cohort study.

    abstract:BACKGROUND:The prognosis of ischemic heart failure (IHF) is worse than non-IHM. Improving the management of IHF remains an urgent demand. In recent years, Qishen Yiqi dripping pills (QSYQ), a type of Chinese herbal medicine (CHM), has been popular for IHF combined with standard western medicine. However, relevant scien...

    journal_title:Medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MD.0000000000013085

    authors: Zhao Z,Wang X,Hou Y,Wang S,Zhai J,Wang C,Mao J,Zhang B

    更新日期:2018-11-01 00:00:00

  • Expression of IL-17 and its gene promoter methylation status are associated with the progression of chronic hepatitis B virus infection.

    abstract::To explore interleukin-17 (IL-17) and its epigenetic regulation during the progression of chronic hepatitis B virus (HBV) infection.A total of 162 patients with chronic HBV infection, including 75 with chronic hepatitis B (CHB), 54 with hepatitis B-associated liver cirrhosis and 33 with hepatitis B-associated hepatoce...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000015924

    authors: Tian CH,Dai J,Zhang W,Liu Y,Yang Y

    更新日期:2019-06-01 00:00:00

  • Effects of hyperbaric oxygen therapy on the expression levels of the inflammatory factors interleukin-12p40, macrophage inflammatory protein-1β, platelet-derived growth factor-BB, and interleukin-1 receptor antagonist in keloids.

    abstract:BACKGROUND:Our study aimed to screen and explore the expression of inflammatory factors in keloid patients and to investigate how hyperbaric oxygen (HBO) therapy affects the expression levels of interleukin-12p40 (IL-12p40), macrophage inflammatory protein-1β (MIP-1β), platelet-derived growth factor-BB (PDGF-BB), and i...

    journal_title:Medicine

    pub_type: 临床试验,杂志文章

    doi:10.1097/MD.0000000000019857

    authors: Hao Y,Dong X,Zhang M,Liu H,Zhu L,Wang Y

    更新日期:2020-04-01 00:00:00

  • Erratum: Treatments for Shoulder Impingement Syndrome: A PRISMA Systematic Review and Network Meta-Analysis: Erratum.

    abstract::[This corrects the article DOI: 10.1097/MD.0000000000000510.]. ...

    journal_title:Medicine

    pub_type: 已发布勘误

    doi:10.1097/01.md.0000484495.36196.d5

    authors:

    更新日期:2016-06-10 00:00:00

  • Cardiac tamponade induced by dabrafenib and trametinib combination therapy for melanoma: Case report.

    abstract:RATIONALE:BRAF and MEK inhibitors (BRAF/MEKi) are targeted therapy for proto-oncogene BRAF mutated metastatic unresectable melanoma. Compared to monotherapy, an increased cardiovascular toxicity is reported with the combination of Dabrafenib and Trametinib. This case report documents Grade 4 cardiac treatment emergent ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012751

    authors: Sundaram VR,Abbas T

    更新日期:2018-11-01 00:00:00

  • Silver dressings for the healing of venous leg ulcer: A meta-analysis and systematic review.

    abstract::This study was aimed to evaluate whether silver-containing dressings were superior to other types of dressings in the treatment of venous leg ulcers (VLU) and their specific advantages.Eight databases (Cochrane Library, PubMed, Web of Science, Ovid-Medline, Wanfang, VIP, China Biology Medicine, and China National Know...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000022164

    authors: Zhao M,Zhang D,Tan L,Huang H

    更新日期:2020-09-11 00:00:00

  • Skeletal muscle metastasis as a first site of recurrence of cervical cancer: A case report and review of the literature.

    abstract:RATIONALE:Cervical cancer primarily spreads through direct invasion or via local lymphatics, and hematogenous metastasis is infrequent. Previous reports have shown that lung, liver, and bone are the organs most frequently affected by hematogenous metastasis of cervical cancer, while skeletal muscle is very rarely invol...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000020056

    authors: Omokawa N,Mabuchi S,Iwai K,Kawahara N,Kawaguchi R,Sugimoto S,Ohbayashi C,Honoki K,Nagai A,Kobayashi H

    更新日期:2020-05-01 00:00:00

  • Favorable glycemic response after pancreatoduodenectomy in both patients with pancreatic cancer and patients with non-pancreatic cancer.

    abstract::Diabetes mellitus (DM) is prevalent in patients with pancreatic cancer and tends to improve after tumor resection. However, the glycemic response of non-pancreatic cancer patients after surgery has not been examined in detail. We aimed to investigate the changes in glucose metabolism in patients with pancreatic cancer...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010590

    authors: Sohn SY,Lee EK,Han SS,Lee YJ,Hwangbo Y,Kang YH,Lee SD,Kim SH,Woo SM,Lee WJ,Hong EK,Park SJ

    更新日期:2018-05-01 00:00:00

  • Genetic Association Between NFKBIA -881A>G Polymorphism and Cancer Susceptibility.

    abstract::Several epidemiological studies have focused on the role of nuclear factor-kappa-B inhibitor-alpha (NFKBIA) -881 A>G polymorphism in cancer susceptibility. However, the published data have led to contentious results. This study was designed to examine the association between -881 A>G polymorphism and cancer risk.Compr...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000001024

    authors: Geng P,Ou J,Li J,Liao Y,Wang N,Sa R,Xiang L,Liang H

    更新日期:2015-08-01 00:00:00

  • Pancreatic carcinosarcoma mimics malignant intraductal papillary mucinous neoplasm: A rare case report and literature review.

    abstract:RATIONALE:Carcinosarcoma, an extremely rare pancreatic primary tumor, is characterized by coexistence of both carcinomatous and sarcomatous components. Due to its rarity, the clinical manifestation and imaging features have not been recognized. An accurate diagnostic method has not been available and a widely accepted ...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000006961

    authors: Li BQ,Liu QF,Chang XY,Hu Y,Chen J,Guo JC

    更新日期:2017-06-01 00:00:00

  • Shunting outcomes in post-hemorrhagic hydrocephalus: A protocol for systematic review and meta-analysis.

    abstract:BACKGROUND:The best treatment option for patients with post-hemorrhagic hydrocephalus (PHH) remains controversial. The objective of the current meta-analysis is to systematically evaluate the long-term outcomes of patients with PHH treated by ventriculoperitoneal shunt (VPS) and lumboperitoneal shunt (LPS). METHODS:We...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000021640

    authors: Sun T,Guan J,You C,Yang J,Li X,Yuan Y,Zhou Y

    更新日期:2020-08-07 00:00:00

  • Calcified inferior vena cava and right atrial myxoma in an 18-month-old male: A case report.

    abstract:INTRODUCTION:Cardiac myxomas are the most frequent primary cardiac tumor in adults. The incidence in pediatric patients is extremely low. Heavy calcification of an atrial myxoma is uncommon in children. CASE PRESENTATION:An 18-month-old boy was admitted for a significant precordial systolic murmur. Transthoracic echoc...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000011073

    authors: Chen R,Deng X,Luo J,Huang P

    更新日期:2018-06-01 00:00:00

  • Application of ultrasound in a congenital cystic adenomatoid malformation in an adult: A case report.

    abstract:INTRODUCTION:Congenital cystic adenomatoid malformation (CCAM) is a rare developmental lung abnormality, that typically manifests in neonates and infants but rarely in adults. Ultrasound is an important method of diagnosing CCAM in neonates and infants; however, few articles have reported the value of transthoracic lun...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000023505

    authors: Xu W,Wen Q,Zha L,Liu C,Huang P

    更新日期:2020-12-04 00:00:00

  • Chemoradiotherapy completion and neutropenia risk in HIV patients with cervical cancer.

    abstract::Cervical cancer (CC) is one of the acquired immunodeficiency syndrome (AIDS) defining diseases and the human immunodeficiency virus (HIV) infection is thought to relate with increased acute toxicity of chemoradiotherapy (CRT).We investigated the effect of HIV status in the incidence of neutropenia associated with cisp...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000011592

    authors: Vendrell I,Ferreira AR,Abrunhosa-Branquinho AN,Semedo PM,Pulido CF,Jorge M,Pina MF,Pinto C,Costa L

    更新日期:2018-07-01 00:00:00