Abstract:
:To our knowledge, the association between antidepressant exposure and endometrial cancer has not been previously explored. Herein, we aim to investigate the association between antidepressant prescription, including novel antidepressants, and the risk for endometrial cancer in a population-based study.Data for the analysis were derived from National Health Insurance Research Database. We identified 8392 cases with a diagnosis of endometrial cancer and 82,432 matched controls. A conditional logistic regression model was used, with adjusting for potentially confounding variables (e.g., comorbid psychiatric diseases, comorbid physical diseases, and other medications). Risk for endometrial cancer in the population-based study sample was categorized by, and assessed as a function of, antidepressant prescription and cumulative dosage.We report no association between endometrial cancer incidence and antidepressant prescription, including those prescribed either selective serotonin reuptake inhibitors (adjusted odds ratio [OR] = 0.98; 95% confidence interval [CI], 0.84-1.15) or serotonin norepinephrine reuptake inhibitors (adjusted OR = 1.14; 95% CI, 0.76-1.71). We also did not identify an association between higher cumulative doses of antidepressant prescription and endometrial cancer.There was no association between antidepressant prescription and endometrial cancer.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Lin CF,Chan HL,Hsieh YH,Liang HY,Chiu WC,Huang KY,Lee Y,McIntyre RS,Chen VCdoi
10.1097/MD.0000000000004178subject
Has Abstractpub_date
2016-07-01 00:00:00pages
e4178issue
29eissn
0025-7974issn
1536-5964pii
00005792-201607190-00010journal_volume
95pub_type
杂志文章相关文献
MEDICINE文献大全abstract:RATIONALE:Testicular capillary hemangioma (TCH) is a rare benign tumor of the testis. To the authors' knowledge, there is currently only a few literatures describing the use of contrast-enhanced ultrasound (CEUS) to diagnose TCH. Accurate preoperative diagnosis of benign tumors can avoid orchiectomy. A case of TCH eval...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014779
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Among all types of cervical spondylitis, cervical spondylitis radiculopathy (CSR) has the highest incidence. The incidence of CSR increases year by year and is generally younger, which has seriously threatened people's quality of life and affected their work and life. This study proposes to improve the recov...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000020846
更新日期:2020-06-26 00:00:00
abstract::The association between the hepatitis C virus (HCV) infection and the risk of myocardial infarction (MI) and stroke has been previously investigated. However, the association between the HCV infection and the risk of venous thromboembolism (VTE) has not been extensively discussed. Using the Longitudinal Health Insuran...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001585
更新日期:2015-09-01 00:00:00
abstract:RATIONALE:Total knee arthroplasty (TKA) is a globally well-accepted surgery because of its good outcome and safety. Although TKA-associated arterial injuries occur, postoperative anterior tibial artery (ATA) occlusion has not been reported yet. Herein, we present a case of ATA occlusion after TKA. PATIENT CONCERNS:A 4...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000016503
更新日期:2019-07-01 00:00:00
abstract::To evaluate the rationality of drug use to treat community-acquired pneumonia (CAP) in children of a Chinese hospital using a set of developed indicators.We performed a retrospective cross-sectional study in West China Second University Hospital. Hospitalized children (0-18 years old) diagnosed with CAP from October 2...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000013224
更新日期:2018-11-01 00:00:00
abstract:RATIONALE:A subdural empyema (SDE) following burr hole drainage of a chronic subdural hematoma (CSDH) can be difficult to distinguish from a recurrence of the CSDH, especially when imaging data is limited to a computed tomography (CT) scan. PATIENTS CONCERNS:All patients underwent burr hole drainage of the CSDH at fir...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010664
更新日期:2018-05-01 00:00:00
abstract::Cancer stem cells (CSCs) are thought to be responsible for tumor relapse and metastasis due to their abilities to self-renew, differentiate, and give rise to new tumors. Cyclooxygenase-2 (COX-2) is highly expressed in several kinds of CSCs, and it helps promote stem cell renewal, proliferation, and radioresistance. Wh...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001806
更新日期:2015-11-01 00:00:00
abstract::We examined whether the responsiveness to an increase in cigarettes price differed by adolescents' cigarette acquisition source. We analyzed data on 6134 youth smokers (grades 7-12) from a cross-sectional survey in Korea with national representativeness. The respondents were classified into one of the following accord...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007311
更新日期:2017-06-01 00:00:00
abstract::Esophageal cancer is a common malignant tumor of the digestive system with a high incidence and a poor prognosis. At the present, CT-based radiomics is providing more and more valuable information. However, the heterogeneity of the study and the poor repeatability of the texture feature parameters have limited its wid...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021470
更新日期:2020-08-07 00:00:00
abstract::The periaqueductal gray (PAG) plays a pivotal role in pain modulation. We attempted to examine the relation between injury of the PAG and central pain in patients with mild traumatic brain injury (TBI).Sixty-one patients with mild TBI with central pain and 31 healthy control subjects were recruited for this study. Vis...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004017
更新日期:2016-06-01 00:00:00
abstract::Hughes (antiphospholipid) syndrome (APS) can mimic multiple sclerosis (MS). We analyzed the clinical, laboratory, and imaging findings of MS-like expression in a cohort of patients with APS in an attempt to identify parameters that might differentiate the 2 entities. We studied 27 patients who were referred to our uni...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/00005792-200001000-00006
更新日期:2000-01-01 00:00:00
abstract::The combination of the direct-acting antivirals, simeprevir (SMV) and sofosbuvir (SOF), was the first highly efficacious interferon-free combination for treating patients with hepatitis C virus (HCV), and was widely used in Italy as a result.The aim of this study was to evaluate effectiveness and safety of SMV in Ital...
journal_title:Medicine
pub_type: 杂志文章,多中心研究
doi:10.1097/MD.0000000000011307
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:Polycystic ovary syndrome (PCOS) is a female endocrine disease with a high incidence. At present, drug treatment is still the main therapeutic strategy for PCOS. Traditional Chinese medicine has a long history in the treatment of menstrual disorders. Shouwu Jiangqi Decoction (SWJQD) is a traditional herbal m...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000019045
更新日期:2020-03-01 00:00:00
abstract::Poikilothermia, the inability to maintain a constant core temperature independent of ambient temperature, markedly influences both the mental and physical function of affected patients; furthermore, prolonged hypothermia can induce numerous complications. To establish the pathophysiology of thermoregulation underlying...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/00005792-199107000-00003
更新日期:1991-07-01 00:00:00
abstract::The aim of the study was to evaluate in human immunodeficiency virus (HIV)-infected patients estimated glomerular filtration rate (eGFR) trajectories during treatment with different protease inhibitors (PIs) or a non-nucleoside reverse transcriptase inhibitor (NNRTI) plus tenofovir (TDF) or abacavir (ABC) and lamivudi...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000003780
更新日期:2016-05-01 00:00:00
abstract::The purpose of this study was to evaluate neutropenia following intravenous immunoglobulin (IVIG) therapy in adults with immune thrombocytopenic purpura (ITP).Our analysis included 88 patients with ITP, who received IVIG from January 2006 to March 2016, at Pusan National University Hospital in Korea. Their white blood...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018624
更新日期:2020-01-01 00:00:00
abstract::The inflammation-based Glasgow Prognostic Score (GPS), which involves C-reactive protein and serum albumin levels, has been reported to be a strong independent predictor of mortality in many cancers. This study aimed to investigate whether the GPS is associated with mortality in patients with acute ST-segment elevatio...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000013615
更新日期:2018-12-01 00:00:00
abstract::Multilevel cervical reconstruction and fusion after cervical tuberculosis has always been a challenge. The current implantation materials for cervical fusion, including titanium mesh, cage, and plate are limited by its inferior biological mechanical characteristics and the properties of the metallic material. This has...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009382
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver condition worldwide. However, its etiology and fundamental pathophysiology for the disease process are poorly understood. In this study, we thus used bioinformatics to identify candidate genes potentially causative of severe NAFLD. ME...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007743
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:The critically ill and surgical patients are at significant risk of delirium, which is associated with a high morbidity and mortality. The association between statin use and the incidence of delirium is still controversial. In this article, we will perform a systematic review and meta-analysis of published s...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000013679
更新日期:2018-12-01 00:00:00
abstract::The relationship of bullying with suicidal ideation among adolescents is controversial. Although depression has been related to bullying and suicidal ideation, little is known about the combined impacts of depression and bullying on suicidal ideation.A sample of 20,509 high school students from Fujian Province were se...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002530
更新日期:2016-02-01 00:00:00
abstract:RATIONALE:Immunoglobulin G4-related disease (IgG4-RD) is regarded as an immune-mediated systemic fibroinflammatory disease. Several studies have linked IgG4-RD to infections such as tuberculosis and actinomycosis. However, the coexistence of IgG4-RD and non-tuberculous mycobacterium (NTM) in a single pulmonary nodule h...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018179
更新日期:2019-11-01 00:00:00
abstract::Adenoid cystic carcinoma (ACC) is one of the most frequent malignancies of salivary glands. The objective of this study was to identify key genes and potential mechanisms during ACC samples.The gene expression profiles of GSE88804 data set were downloaded from Gene Expression Omnibus. The GSE88804 data set contained 2...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018676
更新日期:2020-01-01 00:00:00
abstract::Pseudoaneurysm of the mitral-aortic intervalvular fibrosa (P-MAIVF) is a rare but potentially fatal entity. Early diagnosis and surgical treatment are particularly important to decrease risk of mortality. The purpose of this study was to explore the echocardiographic characteristics and outcome of P-MAIVF and to evalu...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000003116
更新日期:2016-03-01 00:00:00
abstract:RATIONALE:Paraneoplastic cerebellar degeneration (PCD) is a rare neurodegenerative syndrome associated with antibodies targeting the Purkinje cells of the cerebellum. Most cases of anti-Yo-associated PCD occur in females, with <20 cases reported in males. Herein, we report a male patient with anti-Yo-associated PCD who...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000021760
更新日期:2020-08-14 00:00:00
abstract:BACKGROUND:Hemocoagulase is isolated and purified from snake venoms. Hemocoagulase agents have been widely used in the prevention and treatment of surgical bleeding. A systematic review was performed to evaluate the effects of hemocoagulase on postoperative bleeding and transfusion in patients who underwent cardiac sur...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000018534
更新日期:2019-12-01 00:00:00
abstract:RATIONALE:Carbapenem-resistant Klebsiella pneumonia (CRKP) infections have been a concerning threat, especially in organ transplant patients with very high mortality. Allograft hemorrhage associated with CRKP infection has never been described. PATIENT CONCERNS:A total of 6 recipients tested positive for CRKP were ide...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018982
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:To explore the safety and efficacy of several special approaches of drainage for deep inaccessible intraabdominal and pelvic abscesses. METHODS:By searching of our institutional database, the clinical and radiologic information of all patients with special approaches of abscesses drainage was collected, con...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000012905
更新日期:2018-10-01 00:00:00
abstract:RATIONALE:Hereditary multiple exostoses (HMEs) is an autosomal dominant skeletal disorder. PATIENT CONCERNS:Six probands of the 6 unrelated Han Chinese families were identified as having HME. These patients had exostoses at multiple sites and significantly affected joints malformation and movement. DIAGNOSES:Heredita...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015692
更新日期:2019-05-01 00:00:00
abstract::VASA, also known as DDX4, is reported to be specifically expressed in cells belonging to the germ cell lineage, both in males and females. Therefore, it could be an informative protein biomarker to be applied on semen to differentiate between obstructive and nonobstructive azoospermia (OA and NOA, respectively). In ad...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007489
更新日期:2017-07-01 00:00:00