Advances Towards Painless Vaccination and Newer Modes of Vaccine Delivery.

Abstract:

:Vaccines have been successful in reducing the mortality and morbidity, but most of them are delivered by intramuscular or intravenous route. They are associated with pain to the baby and bring lot of anxiety for the parents. There has been a marked increase in the number of injections required in first two years of life for completing the vaccination schedule. Hence, there is a need to have a painless vaccine delivery system. Numerous new routes of vaccination like, oral, nasal and transdermal routes are being tried. Oral polio and intranasal influenza have already been a success. Other newer approaches like edible vaccines, nasal sprays, dry powder preparations, jet injectors, microneedles and nanopatches are promising in delivering painless vaccines. Many of them are under clinical trials. These vaccine delivery systems will not only be painless but also cost effective, safe and easy to administer in mass population. They may be devoid of the need of cold chain. Painless delivery system will ensure better compliance to vaccination schedule.

journal_name

Indian J Pediatr

authors

Garg N,Aggarwal A

doi

10.1007/s12098-017-2377-2

subject

Has Abstract

pub_date

2018-02-01 00:00:00

pages

132-138

issue

2

eissn

0019-5456

issn

0973-7693

pii

10.1007/s12098-017-2377-2

journal_volume

85

pub_type

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