The SaeRS Two-Component System Controls Survival of Staphylococcus aureus in Human Blood through Regulation of Coagulase.

abstract：:Burkholderia cenocepacia is an opportunistic respiratory pathogen of individuals with cystic fibrosis (CF). Some strains of B. cenocepacia are highly transmissible and resistant to almost all antibiotics. Approximately one-third of B. cenocepacia infected CF patients go on to develop fatal "cepacia syndrome." During t...

journal_title：Frontiers in cellular and infection microbiology

authors： Ganesan S,Sajjan US

更新日期：2012-01-11 00:00:00

abstract：:Ticks modulate their hosts' defense responses by secreting a biopharmacopiea of hundreds to thousands of proteins and bioactive chemicals into the feeding site (tick-host interface). These molecules and their functions evolved over millions of years as ticks adapted to blood-feeding, tick lineages diverged, and host-s...

journal_title：Frontiers in cellular and infection microbiology

authors： Mans BJ,Featherston J,de Castro MH,Pienaar R

更新日期：2017-09-25 00:00:00

abstract：:Postpartum depressive disorder (PPD) is a unique subtype of major depressive disorder and a substantial contributor to maternal morbidity and mortality. However, the pathogenesis of PPD has still remained elusive, and it may associate with genetic and environmental factors. Gut microbiota has already been proved to be...

journal_title：Frontiers in cellular and infection microbiology

authors： Zhou Y,Chen C,Yu H,Yang Z

更新日期：2020-09-29 00:00:00

abstract：:Escherichia coli carrying prophage with genes that encode for Shiga toxins are categorized as Shiga toxin-producing E. coli (STEC) pathotype. Illnesses caused by STEC in humans, which are often foodborne, range from mild to bloody diarrhea with life-threatening complications of renal failure and hemolytic uremic syndr...

journal_title：Frontiers in cellular and infection microbiology

authors： Ludwig JB,Shi X,Shridhar PB,Roberts EL,DebRoy C,Phebus RK,Bai J,Nagaraja TG

更新日期：2020-07-29 00:00:00

abstract：:Objectives:Pneumocystis jirovecii pneumonia (PCP) is an AIDS-defining illness. In patients with HIV, the benefit of PCP prophylaxis is well-defined when the CD4 T-cell count decreases below 200 cells/μL. In other immunocompromised patients, the value of PCP prophylaxis is not always as well-established. This study aim...

journal_title：Frontiers in cellular and infection microbiology

authors： Dunbar A,Schauwvlieghe A,Algoe S,van Hellemond JJ,Reynders M,Vandecasteele S,Boelens J,Depuydt P,Rijnders B

更新日期：2020-05-15 00:00:00

abstract：:The natural history of genital Chlamydia trachomatis infections can vary widely; infections can spontaneously resolve but can also last from months to years, potentially progressing to cause significant pathology. The host and bacterial factors underlying this wide variation are not completely understood, but emphasiz...

journal_title：Frontiers in cellular and infection microbiology

authors： Aiyar A,Quayle AJ,Buckner LR,Sherchand SP,Chang TL,Zea AH,Martin DH,Belland RJ

更新日期：2014-06-03 00:00:00

abstract：:Cytokinesis, or the division of the cytoplasm, following the end of mitosis or meiosis, is accomplished in animal cells, fungi, and amoebae, by the constriction of an actomyosin contractile ring, comprising filamentous actin, myosin II, and associated proteins. However, despite this being the best-studied mode of cyto...

journal_title：Frontiers in cellular and infection microbiology

authors： Hammarton TC

更新日期：2019-11-21 00:00:00

abstract：:Diethylhexylphthalate (DEHP), acting as an endocrine disruptor, disturbed reproductive health. Here, we evaluated the effects of Lactobacillus plantarum TW1-1 (L. plantarum TW1-1) on DEHP-induced testicular damage in adult male mice. Results showed that oral supplementation of L. plantarum TW1-1 significantly increase...

journal_title：Frontiers in cellular and infection microbiology

authors： Tian X,Yu Z,Feng P,Ye Z,Li R,Liu J,Hu J,Kakade A,Liu P,Li X

更新日期：2019-06-26 00:00:00

abstract：:Escherichia coli O157:H7 is a notorious pathogen often contracted by intake of contaminated water or food. Infection with this agent is associated with a broad spectrum of illness ranging from mild diarrhea and hemorrhagic colitis to the potentially fatal hemolytic uremic syndrome (HUS). Treating E. coli O157:H7 infec...

journal_title：Frontiers in cellular and infection microbiology

authors： Rahal EA,Kazzi N,Nassar FJ,Matar GM

更新日期：2012-11-15 00:00:00

abstract：:Melioidosis is a neglected tropical disease with high mortality rate. It is caused by the Gram-negative, CDC category B select agent Burkholderia pseudomallei (B. ps) that is intrinsically resistant to first-line antibiotics. An antibody-based vaccine is likely to be the most effective control measure. Previous studie...

journal_title：Frontiers in cellular and infection microbiology

authors： Chaichana P,Kronsteiner B,Rongkard P,Teparrukkul P,Limmathurotsakul D,Chantratita N,Day NPJ,Fletcher HA,Dunachie SJ

更新日期：2020-08-26 00:00:00

abstract：:Cytolethal distending toxin (CDT) produced by Campylobacter jejuni contains three subunits: CdtA, CdtB, and CdtC. Among these three toxin subunits, CdtB is the toxic moiety of CDT with DNase I activity, resulting in DNA double-strand breaks (DSB) and, consequently, cell cycle arrest at the G2/M stage and apoptosis. Ra...

journal_title：Frontiers in cellular and infection microbiology

authors： Lin HJ,Liu HH,Lin CD,Kao MC,Chen YA,Chiang-Ni C,Jiang ZP,Huang MZ,Lin CJ,Lo UG,Lin LC,Lai CK,Lin H,Hsieh JT,Chiu CH,Lai CH

更新日期：2017-06-08 00:00:00

abstract：:Murid and cricetid rodents were previously believed to be the principal reservoir hosts of hantaviruses. Recently, however, multiple newfound hantaviruses have been discovered in shrews, moles, and bats, suggesting a complex evolutionary history. Little is known about the genetic diversity and geographic distribution ...

journal_title：Frontiers in cellular and infection microbiology

authors： Kikuchi F,Aoki K,Ohdachi SD,Tsuchiya K,Motokawa M,Jogahara T,Sơn NT,Bawm S,Lin KS,Thwe TL,Gamage CD,Ranorosoa MC,Omar H,Maryanto I,Suzuki H,Tanaka-Taya K,Morikawa S,Mizutani T,Suzuki M,Yanagihara R,Arai S

更新日期：2020-08-27 00:00:00

abstract：:Vibrio parahaemolyticus elicits gastroenteritis by deploying Type III Secretion Systems (TTSS) to deliver effector proteins into epithelial cells of the human intestinal tract. The bacteria must adhere to the human cells to allow colonization and operation of the TTSS translocation apparatus bridging the bacterium and...

journal_title：Frontiers in cellular and infection microbiology

authors： O'Boyle N,Boyd A

更新日期：2014-01-10 00:00:00

abstract：:Previous studies demonstrated that oral antibiotic (ABX) treatment prior to and during influenza A virus (IAV) infection of adult mice profoundly altered gut microbiota (GM) and was associated with increased susceptibility and impaired immunity to IAV. We examined the impact of ABX during critical times relevant to th...

journal_title：Frontiers in cellular and infection microbiology

authors： Fuglsang E,Pizzolla A,Krych L,Nielsen DS,Brooks AG,Frøkiær H,Reading PC

更新日期：2018-09-12 00:00:00

abstract：:Streptococcus pyogenes is a significant pathogen of humans, annually causing over 700,000,000 infections and 500,000 deaths. Virulence in S. pyogenes is closely linked to mobile genetic elements like phages and chromosomal islands (CI). S. pyogenes phage-like chromosomal islands (SpyCI) confer a complex mutator phenot...

journal_title：Frontiers in cellular and infection microbiology

authors： Nguyen SV,McShan WM

更新日期：2014-08-12 00:00:00

abstract：:Prompt and effective elicitation of protective immunity is highly relevant for cases of rapidly deteriorating fatal diseases, such as plague, which is caused by Yersinia pestis. Here, we assessed the potential of a live vaccine to induce rapid protection against this infection. We demonstrated that the Y. pestis EV76 ...

journal_title：Frontiers in cellular and infection microbiology

authors： Zauberman A,Vagima Y,Tidhar A,Aftalion M,Gur D,Rotem S,Chitlaru T,Levy Y,Mamroud E

更新日期：2017-06-21 00:00:00

abstract：:Pediculus humanus is an obligate bloodsucking ectoparasite of human that includes two ecotypes, head louse and body louse, which differ slightly in morphology and biology, but have distinct ecologies. Phylogenetically, they are classified on six mitochondrial clades (A, B, C, D, E, and F), head louse encompasses the f...

journal_title：Frontiers in cellular and infection microbiology

authors： Amanzougaghene N,Fenollar F,Raoult D,Mediannikov O

更新日期：2020-01-21 00:00:00

abstract：:Streptococcus dentisani 7746, isolated from dental plaque of caries-free individuals, has been shown to have several beneficial effects in vitro which could contribute to promote oral health, including an antimicrobial activity against oral pathogens by the production of bacteriocins and a pH buffering capacity throug...

journal_title：Frontiers in cellular and infection microbiology

authors： Ferrer MD,López-López A,Nicolescu T,Perez-Vilaplana S,Boix-Amorós A,Dzidic M,Garcia S,Artacho A,Llena C,Mira A

更新日期：2020-08-31 00:00:00

abstract：:Ten bacteriophages were isolated from faeces and their lytic effects assayed on 103 pathogenic and non-pathogenic Enterobacteriaceae. Two phages (DT1 and DT6) were selected based on their host ranges, and their lytic effects on pathogenic E. coli strains inoculated on pieces of beef were determined. We evaluated the r...

journal_title：Frontiers in cellular and infection microbiology

authors： Tomat D,Migliore L,Aquili V,Quiberoni A,Balagué C

更新日期：2013-06-06 00:00:00

abstract：:To define the bottlenecks that restrict antigen expression after oral administration of viral-vectored vaccines, we tracked vectors derived from the human adenovirus type 5 at whole body, tissue, and cellular scales throughout the digestive tract in a murine model of oral delivery. After intragastric administration of...

journal_title：Frontiers in cellular and infection microbiology

authors： Revaud J,Unterfinger Y,Rol N,Suleman M,Shaw J,Galea S,Gavard F,Lacour SA,Coulpier M,Versillé N,Havenga M,Klonjkowski B,Zanella G,Biacchesi S,Cordonnier N,Corthésy B,Ben Arous J,Richardson JP

更新日期：2018-01-25 00:00:00

abstract：:Zoysia japonica, in Brazil, is commonly infected by Rhizoctonia solani (R. solani) in humid and cool weather conditions. Eight isolates of R. solani, previously identified as belonging to the AG2-2 LP anastomosis group, isolated from samples from large path symptoms, were collected from three counties in São Paulo sta...

journal_title：Frontiers in cellular and infection microbiology

authors： Picarelli MASC,Forgia M,Rivas EB,Nerva L,Chiapello M,Turina M,Colariccio A

更新日期：2019-07-12 00:00:00

abstract：:Lipophilic yeasts of the genus Malassezia are important skin commensals and opportunistic skin pathogens in a variety of animals. The species M. pachydermatis was first isolated from the skin of a captive Indian rhinoceros with an exfoliative dermatitis in 1925, recognized as an important otic pathogen of dogs in the ...

journal_title：Frontiers in cellular and infection microbiology

authors： Guillot J,Bond R

更新日期：2020-02-28 00:00:00

abstract：:The Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) is a heterotrimeric AB2 toxin capable of inducing lymphocytes, and other cell types, to undergo cell cycle arrest and apoptosis. Exposure to Cdt results in binding to the cell surface followed by internalization and translocation of the active...

journal_title：Frontiers in cellular and infection microbiology

authors： Boesze-Battaglia K,Walker LP,Dhingra A,Kandror K,Tang HY,Shenker BJ

更新日期：2017-11-14 00:00:00

abstract：:Escherichia coli O157:H7 and other pathogenic E. coli strains are enteric pathogens associated with food safety threats and which remain a significant cause of morbidity and mortality worldwide. In the current study, we investigated whether enterohemorrhagic E. coli (EHEC), Shiga toxin-producing E. coli (STEC), and en...

journal_title：Frontiers in cellular and infection microbiology

authors： Botkin DJ,Galli L,Sankarapani V,Soler M,Rivas M,Torres AG

更新日期：2012-02-14 00:00:00

abstract：:Non-encapsulated Streptococcus pneumoniae often possess two genes, aliB-like ORF 1 and aliB-like ORF 2, in place of capsule genes. AliB-like ORF 1 is thought to encode a substrate binding protein of an ABC transporter which binds peptide SETTFGRDFN, found in 50S ribosomal subunit protein L4 of Enterobacteriaceae. Here...

journal_title：Frontiers in cellular and infection microbiology

authors： Nasher F,Kwun MJ,Croucher NJ,Heller M,Hathaway LJ

更新日期：2019-09-10 00:00:00

abstract：:Rheumatoid Arthritis (RA) has been increasingly associated with perturbations to the microbial communities that reside in and on the body (the microbiome), in both human and animal studies. To date, such studies have mainly focused on the microbial communities that inhabit the gut and oral cavity. Mounting evidence su...

journal_title：Frontiers in cellular and infection microbiology

authors： Hammad DBM,Hider SL,Liyanapathirana VC,Tonge DP

更新日期：2020-01-22 00:00:00

abstract：:Background:Pseudomonas aeruginosa causes severe chronic respiratory diseases and is associated with recalcitrant chronic rhinosinusitis (CRS). P. aeruginosa exoproteins contain virulence factors and play important roles in the pathogenicity of P. aeruginosa, however their role in CRS pathophysiology remains unknown. M...

journal_title：Frontiers in cellular and infection microbiology

authors： Li J,Ramezanpour M,Fong SA,Cooksley C,Murphy J,Suzuki M,Psaltis AJ,Wormald PJ,Vreugde S

更新日期：2019-02-27 00:00:00

abstract：:Emerging antibiotic resistance in pathogenic bacteria like Mycobacterium sp., poses a threat to human health and therefore calls for the development of novel antibacterial strategies. We have recently discovered that bacterial membrane peptides, such as KdpF, possess anti-virulence properties when overproduced in path...

journal_title：Frontiers in cellular and infection microbiology

authors： Rosas Olvera M,Vivès E,Molle V,Blanc-Potard AB,Gannoun-Zaki L

更新日期：2017-04-06 00:00:00

abstract：:Natural killer (NK) cells are critical for targeting and killing tumor, virus-infected and stressed cells as a member of the innate immune system. Recently, NK cells have also emerged as key regulators of adaptive immunity and have become a prominent therapeutic target for cancer immunotherapy and infection control. N...

journal_title：Frontiers in cellular and infection microbiology

authors： Pierce S,Geanes ES,Bradley T

更新日期：2020-05-19 00:00:00

abstract：:Background: Intraocular tuberculosis (IOTB), an extrapulmonary manifestation of tuberculosis of the eye, has unique and varied clinical presentations with poorly understood pathogenesis. As it is a significant cause of inflammation and visual morbidity, particularly in TB endemic countries, it is essential to study th...

journal_title：Frontiers in cellular and infection microbiology

authors： Abhishek S,Saikia UN,Gupta A,Bansal R,Gupta V,Singh N,Laal S,Verma I

更新日期：2018-10-02 00:00:00