Abstract：
PURPOSE OF REVIEW:We reviewed the literature to determine what role, if any, radical prostatectomy should play in the treatment of high-risk and/or node-positive prostate cancer. RECENT FINDINGS:The AUA, NCCN, and EAU all include radical prostatectomy as a treatment option for high-risk prostate cancer based on evidence that has shown improvements in biochemical-free and disease-specific survival. Lymph node-positive patients may also derive benefit from radical prostatectomy with lymph node dissection, however, only retrospective studies with high risk of selection bias have been published to date. High-risk prostate cancer is a heterogeneous disease representing a wide range of disease characteristics. Radical surgery, historically avoided in such patients, may now be considered a valid treatment option for select cases. The adverse effects of surgery using modern techniques lead to similar quality of life outcomes as radiation therapy, and treatment of the primary tumor is likely beneficial when compared to ADT alone.
journal_name
Curr Urol Repjournal_title
Current urology reportsauthors
Matulay JT,DeCastro GJdoi
10.1007/s11934-017-0703-xsubject
Has Abstractpub_date
2017-07-01 00:00:00pages
53issue
7eissn
1527-2737issn
1534-6285pii
10.1007/s11934-017-0703-xjournal_volume
18pub_type
杂志文章,评审abstract：:Complementary and alternative medicine (CAM) has recently attracted national attention in the United States because of its widespread use and associated cost. CAM covers a broad spectrum of healing philosophies and approaches. Despite its widespread use, little is known about its safety, efficacy, cost effectiveness, ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-001-0084-y
更新日期：2001-06-01 00:00:00
abstract：:Benign prostatic hyperplasia (BPH) is a disease condition characterized by abnormal prostate growth in conjunction with distinct lower urinary tract symptoms. This paper considers the extent to which the prostatic vascular system contributes to normal prostate growth control as well as whether abnormal blood flow patt...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-002-0051-2
更新日期：2002-08-01 00:00:00
abstract：PURPOSE OF REVIEW:Therapeutic options for the management of lower urinary tract symptoms (LUTS) secondary to benign prostatic enlargement (BPE) have considerably increased in recent years. However, the ideal timing to initiate medical treatment of LUTS/BPE has not been fully established. The aim of this review was to s...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0823-y
更新日期：2018-07-09 00:00:00
abstract：:Global improvements in water quality, management of infectious diseases, and other medical therapeutics have resulted in a growing population of healthy aging men. One obligate anatomic consequence of aging for these men is the development of benign prostatic hyperplasia (BPH) with secondary bladder outlet obstruction...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-014-0403-8
更新日期：2014-05-01 00:00:00
abstract：:Erectile dysfunction (ED) is common after radical prostatectomy (RP). ED has a negative impact on health-related quality of life. Penile rehabilitation is defined as the use of any drug or device at or after RP to maximize erectile function recovery. The purpose of penile rehabilitation is the prevention of corpus cav...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-009-0037-4
更新日期：2009-05-01 00:00:00
abstract：PURPOSE OF REVIEW:Patient-reported outcome measures (PROMs) are tools that are widely used by clinicians and researchers across different medical specialties. In this review, we examine the use of PROMs in the evaluation of female pelvic floor disorders (PFD). RECENT FINDINGS:PROM development in the assessment of urin...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-019-0888-2
更新日期：2019-03-27 00:00:00
abstract：PURPOSE OF REVIEW:Urethral strictures that are refractory to initial management present unique challenges to the reconstructive surgeon. Treatment trends have shifted as new tissue resources are becoming available. There is renewed interest in old methods as skill and technique have improved. We describe the scope of t...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0769-0
更新日期：2018-02-26 00:00:00
abstract：BACKGROUND:Vesico-vaginal fistulae (VVF) remain the most prevalent genitourinary fistula detrimentally impacting quality of life. PURPOSE OF THE REVIEW:The purpose of this review is to examine relevant literature on management of VVF. RECENT FINDINGS:Obstructed labor is the leading cause of VVF in the developing worl...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-017-0708-5
更新日期：2017-08-01 00:00:00
abstract：PURPOSE OF REVIEW:Recurrent urinary tract infections are a common condition that can impact patients' quality of life. The purpose of this review is to summarize and analyze the literature regarding the distress that these infections can cause to patients and provide guidance to clinicians on how to improve care of the...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0849-1
更新日期：2018-10-18 00:00:00
abstract：:The development of a lymphocele after pelvic surgery is a well-documented complication, especially where pelvic lymph node dissection (PLND) is part of the operation. However, not all lymphoceles are symptomatic and require treatment. Most lymphoceles spontaneously resolve, and even lymphoceles that become symptomatic...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-014-0445-y
更新日期：2014-10-01 00:00:00
abstract：:The Infectious Diseases Society of America has published guidelines for the treatment of uncomplicated cystitis. Recommendations are that for healthy, adult, nonpregnant women with bacterial cystitis, 3 days of trimethoprim/ sulfamethoxazole (TMP/SMZ) or trimethoprim alone is standard therapy in those regions where le...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-001-0072-2
更新日期：2001-08-01 00:00:00
abstract：:As bladder reconstruction strategies evolve, a feasible and safe source of transplantable urothelium becomes a major consideration for patients with advanced bladder disease, particularly cancer. Pluripotent stem cells, such as embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), are attractive cand...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-014-0466-6
更新日期：2015-01-01 00:00:00
abstract：:The objective of this review is to discuss the main goals of pelvic organ prolapse repair. Pelvic organ prolapse symptoms are variable, and prolapse degree does not necessarily correlate with perceived symptoms or other associated conditions including urinary, defecatory, and sexual dysfunction. Treatment for pelvic o...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-013-0385-y
更新日期：2014-02-01 00:00:00
abstract：:This paper is aimed at focusing on the nerve-sparing aspect of the robotic prostatectomy. It reviews the existing principles and presents the arguments based on robotic fresh cadaver dissections and from actual robotic prostatectomy cases. ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-005-0080-8
更新日期：2005-03-01 00:00:00
abstract：:Vaginal vault prolapse is a challenging form of pelvic organ prolapse that occurs in combination with cystocele, rectocele, or enterocele in nearly 75% of affected patients. Clinical presentation will vary depending on the associated defects. Any successful therapy for vaginal vault prolapse will depend on a thorough ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-007-0038-0
更新日期：2007-09-01 00:00:00
abstract：:Urgency and urinary urge incontinence are troublesome and complex symptoms that can complicate the diagnosis and treatment of stress urinary incontinence. Despite this fact, first-line intervention frequently is directed toward the incompetent bladder neck using surgical approaches. Persistent urgency or detrusor inst...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-004-0065-z
更新日期：2004-12-01 00:00:00
abstract：:Phthalates are part of a class of high-volume industrial chemicals used ubiquitously in health care as well as household products. Biomarker studies have confirmed the widespread presence of these chemicals in both humans and animals. As a class, phthalates have been implicated in diseases and birth anomalies of the g...
journal_title：Current urology reports
pub_type： 杂志文章
doi：10.1007/s11934-012-0261-1
更新日期：2012-08-01 00:00:00
abstract：:Despite accumulating evidence that inflammation may affect the development of prostate cancer, responsible causes of intraprostatic inflammation remain elusive. This review presents epidemiologic literature on infections, particularly sexually transmitted and other ascending urogenital infections, as possible causes o...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-008-0042-z
更新日期：2008-05-01 00:00:00
abstract：:Congenital abnormalities, cancer, trauma, infection, inflammation, iatrogenic injuries, and other conditions may lead to genitourinary organ damage or loss, requiring eventual reconstruction. Tissue engineering follows the principles of cell transplantation, materials science, and engineering toward the development of...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-001-0030-z
更新日期：2001-02-01 00:00:00
abstract：:Correct staging of prostate cancer at initial diagnosis, as well as accurate staging and tumor localization with biochemical recurrence, remains generally inaccurate with current imaging techniques. Newer modalities are being investigated to accurately identify patients with prostate cancer at different stages of dise...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-006-0018-9
更新日期：2006-05-01 00:00:00
abstract：:Nodal staging in prostate cancer is suboptimal both with respect to current imaging modalities and pelvic lymph node dissection, and thus other techniques are being explored. Lymphotropic nanoparticle-enhanced MRI, also called magnetic resonance lymphography (MRL), is a technique that has shown high sensitivity (65-92...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-013-0389-7
更新日期：2014-03-01 00:00:00
abstract：:Laparoscopic surgery was originally developed by gynecologists and general surgeons. Based on their experience, the first successful laparoscopic procedures in urology were performed transperitoneally. However, this novel technique transformed traditionally retroperitoneal procedures into transperitoneal procedures, g...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-004-0020-z
更新日期：2004-04-01 00:00:00
abstract：:Preservation of postoperative urinary continence remains the primary concern of all men and their surgeons following robot-assisted radical prostatectomy (RARP). Without doubt, continence is the most important quality of life issue following radical prostatectomy. Identification of difficulties and lessons learned ove...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-012-0295-4
更新日期：2013-02-01 00:00:00
abstract：:Chronic nonbacterial prostatitis, or urological chronic pelvic pain syndrome (UCPPS), remains a common and often challenging disorder to evaluate and treat. Employing a more holistic approach, including urological therapy, physical therapy, and psychosocial perspectives, may be more appropriate for most patients. Grow...
journal_title：Current urology reports
pub_type： 杂志文章
doi：10.1007/s11934-009-0047-2
更新日期：2009-07-01 00:00:00
abstract：PURPOSE OF REVIEW:The goal of this chapter is to review the recent epidemiologic trends of kidney stone disease and discuss the impact of the increasing incidence of nephrolithiasis among children on adults with respect to extra-renal manifestations, surgical management, and secondary prevention. RECENT FINDINGS:Among...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-017-0691-x
更新日期：2017-06-01 00:00:00
abstract：PURPOSE OF REVIEW:The classification of morphologically normal sperm has been progressively redefined. Concurrently, our understanding of the significance of sperm morphology in relation to male factor infertility has evolved. In this review, we will discuss the evolution of sperm morphology assessment and factors that...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-019-0911-7
更新日期：2019-06-15 00:00:00
abstract：:Significant clinical and basic science advances in the field of sexual medicine have facilitated investigation of the link between endothelial dysfunction and erectile dysfunction. Most sexual medicine practitioners accept the premise that in aging men with risk factors such as increased waist circumference, diabetes,...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-007-0054-0
更新日期：2007-11-01 00:00:00
abstract：:The prostate-specific antigen (PSA) era has increased the rates of prostate cancer detection and treatment, while reducing the risk of death from prostate cancer in the US. Image-guided prostate biopsy techniques have led to stage migration and the detection and treatment of lower risk prostate cancers. Improved techn...
journal_title：Current urology reports
pub_type： 杂志文章
doi：10.1007/s11934-012-0285-6
更新日期：2012-12-01 00:00:00
abstract：PURPOSE OF REVIEW:This review summarizes the latest reports in inflatable penile prosthesis (IPP) complication management. RECENT FINDINGS:IPP complications are rare, and reports are limited to retrospective studies. However, recent multi-institutional studies and use of national databases have provided further insigh...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-019-0872-x
更新日期：2019-01-30 00:00:00
abstract：:For years the bladder epithelium has been the focus for diagnosing and treating the frequency, urgency, and pelvic pain of interstitial cystitis. However, many patients have not found symptom relief with these therapies. Pelvic floor dysfunction is often present in these patients, yet it is often untreated. Pelvic flo...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-006-0053-6
更新日期：2006-11-01 00:00:00
