Insights into the role of the intestinal microbiota in colon cancer.

abstract：:Endoscopic argon plasma coagulation and bipolar electrocautery are currently preferred treatments for chronic radiation proctitis, but ulcerations and strictures frequently occur. Radiofrequency ablation (RFA) has been successful for mucosal ablation in the esophagus. Here we report the efficacy of RFA with the BarRx ...

journal_title：Therapeutic advances in gastroenterology

authors： Zhou C,Adler DC,Becker L,Chen Y,Tsai TH,Figueiredo M,Schmitt JM,Fujimoto JG,Mashimo H

更新日期：2009-01-01 00:00:00

abstract：:Hereditary pancreatitis shares a majority of clinical and morphologic features with chronic alcoholic pancreatitis, but may present at an earlier age. The term hereditary pancreatitis has primarily been associated with mutations in the serine protease 1 gene (PRSS1) which encodes for cationic trypsinogen. PRSS1 mutati...

journal_title：Therapeutic advances in gastroenterology

authors： Patel MR,Eppolito AL,Willingham FF

更新日期：2013-03-01 00:00:00

abstract：:Rates of transmission of hepatitis B virus (HBV) infection from organ donors with HBV markers to recipients along with reactivation of HBV during immunosuppression following transplantation have fallen significantly with the advent of hepatitis B immune globulin (HBIg) and effective antiviral therapy. Although the ava...

journal_title：Therapeutic advances in gastroenterology

authors： John S,Andersson KL,Kotton CN,Hertl M,Markmann JF,Cosimi AB,Chung RT

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Few reports have described endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA) for biliary lesions. In addition, adverse events were not completely examined in previous reports, due to the inclusion of cases in which biliary stents had already been placed. The present study aimed to investigate t...

journal_title：Therapeutic advances in gastroenterology

authors： Onda S,Ogura T,Kurisu Y,Masuda D,Sano T,Takagi W,Fukunishi S,Higuchi K

更新日期：2016-05-01 00:00:00

abstract：:Pancreatic neuroendocrine tumors (pNETs) are relatively rare malignancies. With secretory tumors such as insulinomas, vasoactive intestinal peptideomas, and gastrinomas, the hormone produced causes the symptom complex (e.g. hypoglycemia, peptic ulcer disease). With nonsecretory NETs, the clinical condition is determin...

journal_title：Therapeutic advances in gastroenterology

authors： Vinik AI,Raymond E

更新日期：2013-09-01 00:00:00

abstract：:Monoclonal antibodies to tumor necrosis factor (TNF) have become a mainstay of the therapeutic armamentarium in inflammatory bowel disease (IBD) over the last 15 years. Although highly effective, primary and secondary nonresponse are common and associated with poor clinical outcomes and significant costs. Multiple cli...

journal_title：Therapeutic advances in gastroenterology

authors： Kopylov U,Seidman E

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Few studies have compared early gastric cancer (EGC) outcomes according to sex and age. METHODS:We retrospectively reviewed 2085 patients who underwent curative gastrectomy for EGC between 1989 and 2000. Prognosis and risk factors for nodal involvement were evaluated according to sex and age. RESULTS:Male ...

journal_title：Therapeutic advances in gastroenterology

authors： Suh DD,Oh ST,Yook JH,Kim BS,Kim BS

更新日期：2017-02-01 00:00:00

abstract：:Functional gastrointestinal disorders, such as irritable bowel syndrome and functional dyspepsia, are complex conditions with multiple factors contributing to their pathophysiology. As a consequence they are difficult to treat and have posed significant challenges to the pharmaceutical industry when trying to develop ...

journal_title：Therapeutic advances in gastroenterology

authors： Sanger GJ,Chang L,Bountra C,Houghton LA

更新日期：2010-09-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is a common and serious health problem with high mortality. Treatment for HCC remains largely unsatisfactory owing to its high recurrence rates and frequent accompanying cirrhosis. In addition, the unique immune environment of the liver promotes tolerance, which, in conjunction with immu...

journal_title：Therapeutic advances in gastroenterology

authors： Kim HY,Park JW

更新日期：2017-10-01 00:00:00

abstract：Background:The incidence of Clostridioides difficile infection (CDI) is increasing in the general population. Data on the epidemiology of CDI in peripartum women - a highly vulnerable patient population - is scarce. The objective of this study was to report the incidence of CDI in peripartum women. Methods:A single-ce...

journal_title：Therapeutic advances in gastroenterology

authors： Saha S,Pardi R,Theiler RN,Pardi DS,Khanna S

更新日期：2020-07-27 00:00:00

abstract：Background:Postoperative pancreatic collection (POPC) is a frequent complication after pancreatectomy. Although percutaneous drainage (PD) has been the treatment of choice for POPC with encapsulation, endoscopic ultrasound-guided transmural drainage (EUS-TD) was recently reported effective for this condition. The main ...

journal_title：Therapeutic advances in gastroenterology

authors： Tamura T,Kitano M,Kawai M,Tanioka K,Itonaga M,Kawaji Y,Nuta J,Hatamaru K,Yamashita Y,Kitahata Y,Miyazawa M,Hirono S,Okada KI,Yamaue H

更新日期：2019-10-24 00:00:00

abstract：METHODS:Suboptimal bowel preparation, present in over 20% of colonoscopies, can severely compromise the effectiveness of the colonoscopy procedure. We surveyed 93 primarily urban minority men and women who underwent asymptomatic 'screening' colonoscopy regarding their precolonoscopy bowel-preparation experience. RESUL...

journal_title：Therapeutic advances in gastroenterology

authors： Basch CH,Basch CE,Wolf RL,Zybert P,Lebwohl B,Shmukler C,Neugut AI,Shea S

更新日期：2013-11-01 00:00:00

abstract：Background:One in four patients with primary Clostridioides difficile infection (CDI) develops recurrent CDI (rCDI). With every recurrence, the chance of a subsequent CDI episode increases. Early identification of patients at risk for rCDI might help doctors to guide treatment. The aim of this study was to externally v...

journal_title：Therapeutic advances in gastroenterology

authors： van Rossen TM,van Dijk LJ,Heymans MW,Dekkers OM,Vandenbroucke-Grauls CMJE,van Beurden YH

更新日期：2021-01-09 00:00:00

abstract：:On 31 December 2019, the WHO China Country Office was informed of cases of pneumonia of unknown etiology detected in Wuhan (Hubei Province of China). In January 2020, a new coronavirus named SARS-CoV2 was isolated and, since that time, SARS-CoV2 related disease (COVID-19) rapidly spread all over the world becoming pan...

journal_title：Therapeutic advances in gastroenterology

authors： Bove V,Schepis T,Boškoski I,Landi R,Orlandini B,Pontecorvi V,Familiari P,Tringali A,Perri V,Costamagna G

更新日期：2020-06-24 00:00:00

abstract：Background:Nonalcoholic fatty liver disease (NAFLD) is correlated with low-grade inflammation and dietary habits. Until today, there have been limited epidemiologic data assessing the role of diet's inflammatory potential on NAFLD. The aim was to evaluate the relationship between an anti-inflammatory diet, as reflected...

journal_title：Therapeutic advances in gastroenterology

authors： Tyrovolas S,Panagiotakos DB,Georgousopoulou EN,Chrysohoou C,Skoumas J,Pan W,Tousoulis D,Pitsavos C

更新日期：2019-06-23 00:00:00

abstract：BACKGROUND:Dual red imaging (DRI), a novel image-enhanced endoscopic technique, is expected to improve visibility of thin vessels, but no reports of the clinical use of DRI in colorectal endoscopic submucosal dissection (ESD) have been published. We aimed to compare the visibility of vessels, demarcation line between t...

journal_title：Therapeutic advances in gastroenterology

authors： Ninomiya Y,Oka S,Tanaka S,Hirano D,Sumimoto K,Tamaru Y,Asayama N,Shigita K,Nishiyama S,Hayashi N,Chayama K

更新日期：2016-09-01 00:00:00

abstract：Aims:Gastric cancer (GC) is the third leading cause of cancer death worldwide, but the burden of disease is not distributed evenly. GC screening routinely occurs in some high-incidence regions/countries and is generally cost-effective, which is attributed largely to the associated GC mortality reduction. In regions of ...

journal_title：Therapeutic advances in gastroenterology

authors： Canakis A,Pani E,Saumoy M,Shah SC

更新日期：2020-07-16 00:00:00

abstract：:Atrial fibrillation (AF) is the most common arrhythmia worldwide and is associated with significant morbidity and mortality. A number of risk factors have been associated with AF, though few studies have explored the association between gastrointestinal and liver diseases and AF. Additionally, AF and treatment for AF ...

journal_title：Therapeutic advances in gastroenterology

authors： Long MT,Ko D,Arnold LM,Trinquart L,Sherer JA,Keppel SS,Benjamin EJ,Helm RH

更新日期：2019-04-02 00:00:00

abstract：Background:Recurrent Clostridium difficile infection (rCDI) is becoming increasingly common. Faecal microbiota transplantation (FMT) is effective for rCDI, but the costs of an FMT and hospital cost savings related to FMT are unknown. The aim of this study was to calculate the cost of an FMT and the total hospital costs...

journal_title：Therapeutic advances in gastroenterology

authors： Dehlholm-Lambertsen E,Hall BK,Jørgensen SMD,Jørgensen CW,Jensen ME,Larsen S,Jensen JS,Ehlers L,Dahlerup JF,Hvas CL

更新日期：2019-04-10 00:00:00

abstract：:In this article we provide a contemporary overview of available clinical data on certolizumab pegol, a pegylated anti-tumor necrosis factor (TNF) alpha agent that comprises a uniquely small protein, and its emerging role as a therapy for Crohn's disease (CD). The results from a comprehensive clinical trial program sug...

journal_title：Therapeutic advances in gastroenterology

authors： Schreiber S

更新日期：2011-11-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is becoming the most common cause of chronic liver disease in the developing world, found in 17-30% of the population in Western countries and 2-4% worldwide. Defined as the accumulation of fatty acid content greater than 5% of liver weight, NAFLD is a spectrum of disease rangi...

journal_title：Therapeutic advances in gastroenterology

authors： Kneeman JM,Misdraji J,Corey KE

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Self-expandable metal stent (SEMS) placement is a minimally invasive treatment for palliation of malignant colorectal strictures and as a bridge to surgery. However, the use of SEMS for benign colorectal diseases is controversial. The purpose of this retrospective study is to evaluate the efficacy and safety...

journal_title：Therapeutic advances in gastroenterology

authors： Cereatti F,Fiocca F,Dumont JL,Ceci V,Vergeau BM,Tuszynski T,Meduri B,Donatelli G

更新日期：2016-03-01 00:00:00

abstract：:The human gastrointestinal tract comprises a series of complex and dynamic organs ranging from the stomach to the distal colon, which harbor immense microbial assemblages that are known to be vital for human health. Until recently, most of the details concerning our gut microbiota remained obscure. Over the past sever...

journal_title：Therapeutic advances in gastroenterology

authors： Kovatcheva-Datchary P,Zoetendal EG,Venema K,de Vos WM,Smidt H

更新日期：2009-07-01 00:00:00

abstract：Objective:i-Scan is a digital image enhancement technology, reported to improve diagnostic performance during endoscopy. Previous studies have investigated the accuracy of i-scan for distinguishing between neoplastic and non-neoplastic colonic polyps and suggested diagnostic accuracy close to that required for use in r...

journal_title：Therapeutic advances in gastroenterology

authors： Glover B,Patel N,Ashrafian H,Teare J

更新日期：2018-12-06 00:00:00

abstract：:Clostridium difficile was first described as a cause of diarrhea in 1978 and in the last three decades has reached an epidemic state with increasing incidence and severity in both healthcare and community settings. There also has been a rise in severe outcomes from C. difficile infection (CDI). There have been tremend...

journal_title：Therapeutic advances in gastroenterology

authors： Khanna S,Pardi DS

更新日期：2014-03-01 00:00:00

abstract：:Malignant tumor cells are equipped with mechanisms that can help them escape the surveillance by host immune system. Immune checkpoint molecules can transduce coinhibitory signals to immunocompetent cells and exert immunosuppressive roles in antitumor immunity. Programmed death-1 (PD-1) and programmed death ligand-1 (...

journal_title：Therapeutic advances in gastroenterology

authors： Liu X,Yang Z,Latchoumanin O,Qiao L

更新日期：2016-11-01 00:00:00

abstract：:Portal hypertension represents one of the major clinical consequences of chronic liver disease, having a deep impact on patients' prognosis and survival. Its pathophysiology defines a pathological increase in the intrahepatic vascular resistance as the primary factor in its development, being subsequently aggravated b...

journal_title：Therapeutic advances in gastroenterology

authors： Vilaseca M,Guixé-Muntet S,Fernández-Iglesias A,Gracia-Sancho J

更新日期：2018-11-25 00:00:00

abstract：:The incidence and prevalence of ulcerative colitis (UC) has been reported to be rising in newly industrialised regions, such as Latin America. Here, we review data from published studies reporting demographics and clinical aspects of UC in Latin America to further understand epidemiology and disease burden. The incide...

journal_title：Therapeutic advances in gastroenterology

authors： Kotze PG,Steinwurz F,Francisconi C,Zaltman C,Pinheiro M,Salese L,Ponce de Leon D

更新日期：2020-07-09 00:00:00

abstract：:Crohn's disease (CD) is a chronic relapsing and remitting disorder of the gastrointestinal tract with no known cure. The inflammation that drives the disease can lead to debilitating symptoms and a number of complications that may lead to surgery. The introduction of biologic therapy a decade ago has offered a new opt...

journal_title：Therapeutic advances in gastroenterology

authors： Panaccione R,Ghosh S

更新日期：2010-05-01 00:00:00

abstract：:The treatment of hepatocellular carcinoma (HCC) remains a challenge, with 1- and 3-year survival rates of 20% and 5%, respectively, and a median survival of 8 months. However, a better understanding of the pathogenesis of HCC, and advances in targeted molecular therapies provide physicians treating this disease with n...

journal_title：Therapeutic advances in gastroenterology

authors： Olsen SK,Brown RS,Siegel AB

更新日期：2010-01-01 00:00:00