Abstract：
BACKGROUND:Although Candida albicans remains the most common fungal isolate from clinical specimens, many studies have detected a shift towards non-albicans Candida species. Despite worrying clinical pictures associated with latter species, there is little information regarding its susceptibility patterns against currently available antifungal agents, with only a small number of strains having been studied. METHODS:We evaluated the in vitro antifungal susceptibilities of clinical isolates of C. orthopsilosis already identified by two-steps PCR-RFLP and reconfirmed by sequence analysis of entire ITS rDNA region, to six antifungal drugs. RESULTS:The resulting MIC50 and MIC90 for all strains (n=18) were in increasing order, as follows: posaconazole (0.016 & 0.063 μg/ml); itraconazole (0.031 & 0.125 μg/ml); amphotericin B (0.5 & 1 μg/ml); fluconazole (0.25 & 0.5 μg/ml) and caspofungin (4 & 8 μg/ml). A uniform pattern of the MIC ranges was seen for amphotericin B, fluconazole, itraconazole, and posaconazole, while a widest range and the highest MICs were observed for caspofungin. CONCLUSION:Although we emphasis on the careful species designation of the clinical isolates of Candida, the antifungal susceptibility patterns of these clinically important organisms may have an application in clinical and epidemiological setting and deserve the implementation of local surveillance programs to monitor.
journal_name
Iran J Public Healthjournal_title
Iranian journal of public healthauthors
Mohammadi R,Mirhendi H,Hedayati MT,Badali Hsubject
Has Abstractpub_date
2017-02-01 00:00:00pages
235-241issue
2eissn
2251-6085issn
2251-6093journal_volume
46pub_type
杂志文章abstract：Background:This study aimed to examine the effect of disease management program (DMP) on the patients with first-time ischemic stroke (IS). Methods:A DMP with 4 parts of performance indicators (PIs, including outpatient, emergency department, inpatient and follow-up treatment) was implemented in patients with stroke i...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
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abstract：:In September 2007 national standard manual was finalized and officially announced as the minimal quality requirements for all medical laboratories in the country. Apart from auditing laboratories, Reference Health Laboratory has performed benchmarking auditing of medical laboratory network (surveys) in provinces. 12(t...
journal_title：Iranian journal of public health
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更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:Treatment of major depression is crucial to decrease the burden of disease. Hence, in this study, the efficacy of Botox was compared with placebo for treatment of patients with major depression. METHODS:In this randomized clinical trial, 28 consecutive patients with major depression were enrolled. The patie...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2017-07-01 00:00:00
abstract：Background:One of the major causes of various work-related health problems among nurses is occupational stress. Hence, the main purpose of the present research was to find association between occupational stress of nurses and risk factors of cardiovascular disease. Methods:In this cross-sectional study, the Osipow job...
journal_title：Iranian journal of public health
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doi：10.18502/ijph.v49i10.4699
更新日期：2020-10-01 00:00:00
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journal_title：Iranian journal of public health
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doi：
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journal_title：Iranian journal of public health
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doi：
更新日期：2017-03-01 00:00:00
abstract：Background:We aimed to evaluate the efficacy of mineral trioxide aggregate (MTA) in the treatment of endodontic disease. Methods:Oversell, 384 patients with endodontic disease treated in Xuzhou Stomatological Hospital, Xuzhou, China, from June 2015 to June 2017 were selected, and randomly divided into four groups with...
journal_title：Iranian journal of public health
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abstract：BACKGROUND:Bladder cancer is the most frequent genitourinary malignancy in Iran. Environmental and genetic factors are the two factors linked with bladder cancer expansion. The aim of this study was to investigate the role of PTEN gene and environmental risk factors on the progression and prognosis of bladder cancer. ...
journal_title：Iranian journal of public health
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abstract：:Chromosome aberration is associated with infertility and isochromosome is a rare chromosomal abnormality potentially associated with infertility or multiple miscarriages. Here we report a man of 29-yr-old diagnosed of infertility from China with rare isochromosome. Peripheral blood lymphocytes were obtained for chromo...
journal_title：Iranian journal of public health
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doi：
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abstract：BACKGROUND:Noise pollution is one of the most harmful ambiance disturbances. It may cause many deficits in ability and activity of persons in the urban and industrial areas. It also may cause many kinds of psychopathies. Therefore, it is very important to measure the risk of this pollution in different area. METHODS:T...
journal_title：Iranian journal of public health
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journal_title：Iranian journal of public health
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更新日期：2010-01-01 00:00:00
abstract：BACKGROUND:Considering the lack of data available on changes of physical activity over time in Iran, this study was designed to evaluate changes in physical activity levels among Iranian adults over a median 6.5 yr period. METHODS:In this population-based cohort study, 3515 participants, aged ≥ 20 yr (2100 females and...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND:Annually millions of Muslims depart to Saudi Arabia for performing a religious pilgrimage called "Hajj". In this ceremony, pilgrims face numerous health hazards and injuries such as pressing in overcrowding, sliding, burning, falling down, traffic accidents etc. The main purpose of this study was to determin...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
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journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
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journal_title：Iranian journal of public health
pub_type： 杂志文章,评审
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更新日期：2017-04-01 00:00:00
abstract：BACKGROUND:Solving the dilemma of the organ shortage in Malaysia requires educating Malaysians about organ donation and transplantation. This paper aims at exploring the average Malaysian households ' preferred channels of campaigns and the preferred campaigners in a family setting, targeting at the dialysis family mem...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2014-07-01 00:00:00
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journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
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journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：10.18502/ijph.v49i7.3587
更新日期：2020-07-01 00:00:00
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journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2013-03-01 00:00:00
abstract：BACKGROUND:The aim of this study was identification of the epidemiology of Prototheca zopfii species from the milk samples of dairy cattle in Isfahan, central Iran. METHODS:Milk samples were obtained from 230 dairy cattle, 130 with and 100 without mastitis, in Isfahan. The samples were cultured in Prototheca Isolation...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
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journal_title：Iranian journal of public health
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doi：
更新日期：2018-08-01 00:00:00
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journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2018-03-01 00:00:00
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journal_title：Iranian journal of public health
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更新日期：2019-04-01 00:00:00
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journal_title：Iranian journal of public health
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doi：
更新日期：2016-08-01 00:00:00
abstract：BACKGROUND:Iodine is essential element in thyroid hormones synthesis and normal growth and development of the brain. Milk and iodine concentrations can be appropriate indicator of body iodine status; in this study, we evaluated the concentrations of urine and milk iodine in newborns and their mothers. METHODS:In a cro...
journal_title：Iranian journal of public health
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doi：
更新日期：2014-10-01 00:00:00
abstract：BACKGROUND:The aim of this study was to assess the levels of Maslow's hierarchy of needs theory had been fulfilled and to compare the Maslow's hierarchy of needs among Iranian different ethnic groups at Tehran University of Medical Sciences (TUMS). METHODS:This research was a descriptive-analytical study which conduct...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2013-05-01 00:00:00
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journal_title：Iranian journal of public health
pub_type： 杂志文章,评审
doi：
更新日期：2014-06-01 00:00:00
abstract：Background:The aim of this study was assessment of the chronic effects of sulfur mustard (SM) among victims. Methods:In this cohort study, 355 SM-exposed subjects from Sardasht, and 123 controls from Rabat, both from West Azerbaijan Province, Iran were included. The spirometric evaluation and the global initiative for...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2018-11-01 00:00:00
abstract：Background:Pseudoexfoliation syndrome (XFS) is pathogenetically related to exfoliative glaucoma (XFG), which is the most common type of secondary glaucoma. We aimed to investigate the relationship between LOXL1 SNPs (rs1048661, rs3825942) and XFS and/or XFG in a cohort of Iranian subjects. Methods:This cross-sectional...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2019-10-01 00:00:00
