Abstract：
Background:Vitamin D might be promising to serve as an adjunctive therapy for pulmonary tuberculosis (TB). However, the results remained controversial. We conducted a systematic review and meta-analysis to evaluate the efficacy and safety of vitamin D in patients with pulmonary TB. Methods:Medline, SCOPUS, Google Scholar, EMBASE, Springer, and Science Direct were searched electronically from inception to Oct 2016. Randomized controlled trials (RCTs) and controlled clinical trials (CCTs) assessing the effect of vitamin D plus anti-tuberculosis treatment (ATT) versus placebo plus ATT on the treatment of pulmonary TB were included. Two investigators independently searched articles, extracted data, and assessed the quality of included studies. Data were analyzed using RevMan 5.3 software. Results:Five studies were included in this meta-analysis. Overall, compared with placebo intervention, vitamin D supplementation was found to have no significant effect on sputum smear negative conversion rates (RR=0.99; 95% CI=0.91 to 1.07; P=0.77), BMI (MD=0.11; 95% CI=-0.85 to 1.07; P=0.82) and ESR (MD=-2.29; 95% CI=-8.87 to 4.30; P=0.50). Conclusion:Vitamin D supplementation showed no influence on the improvement of sputum smear-negative conversion rates and BMI, as well as the decrease in ESR.
journal_name
Iran J Public Healthjournal_title
Iranian journal of public healthauthors
Wang J,Feng M,Ying S,Zhou J,Li Xsubject
Has Abstractpub_date
2018-04-01 00:00:00pages
466-472issue
4eissn
2251-6085issn
2251-6093journal_volume
47pub_type
杂志文章,评审abstract：BACKGROUND:Exposure to mercury (Hg) as a heavy metal can cause health effects. The objective of this study was to assess occupational exposure to Hg in a chlor-alkali petrochemical industry in Iran by determining of Hg concentrations in air, blood and urine samples. METHODS:The study was performed on 50 exposed subjec...
journal_title：Iranian journal of public health
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journal_title：Iranian journal of public health
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doi：
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journal_title：Iranian journal of public health
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journal_title：Iranian journal of public health
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journal_title：Iranian journal of public health
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journal_title：Iranian journal of public health
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journal_title：Iranian journal of public health
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doi：
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