Clinical outcome after endoscopic submucosal dissection for early gastric cancer of absolute and expanded indication.


:This study evaluated the clinical outcome of endoscopic submucosal dissection (ESD) in minute submucosa (SM) invasion or undifferentiated early gastric cancer (EGC) and analyzed factors related to local recurrence after ESD.We retrospectively reviewed the chart of EGC patients, who underwent ESD at our tertiary hospital between January 2009 and 2015. The patients' characteristics and clinical outcomes were compared among an absolute indication, minute SM invasion, and undifferentiated EGC group.Of 885 total patients, 729 composed the absolute indication group; 65, the differentiated, SM invasion group; and 51, the undifferentiated, confined mucosa group. Follow-up was conducted for average (± standard deviation) 34.12 (± 10.6) months; as compared to the absolute indication group, both en bloc resection and curative resection rate were low in the other 2 groups, but there were no significant differences in procedure-related complication, local recurrence, and survival rate. Comparing the cases of ESD performed at our hospital from 2005 to 2009 with those performed between 2009 and 2015, en bloc resection (80.5% vs 89.1%, P = .001) and curative resection rate (86.2% vs 92.1%, P = .011) were higher in the latter study. Noncurative resection and tumor size of more than 2 cm were factors associated with local recurrence.ESD in minute SM invasion or undifferentiated EGC showed an unfavorable short-term outcome as compared to that in the absolute indication group, but there were no differences in local recurrence and overall survival rate. Therefore, in minute SM invasion or undifferentiated EGC patients, ESD could be recommended as a therapeutic option.


Medicine (Baltimore)




Kim JS,Kang SH,Moon HS,Lee ES,Kim SH,Sung JK,Lee BS,Jeong HY




Has Abstract


2017-04-01 00:00:00
















  • Change in lipoprotein-associated phospholipase A2 and its association with cardiovascular outcomes in patients with acute coronary syndrome.

    abstract::Lipoprotein-associated phospholipase A2 (Lp-PLA2) probably plays an important role in the development of acute coronary syndrome (ACS). However, alterations of Lp-PLA2 levels during ACS and its association with cardiovascular outcome are unclear. Our aim was to investigate the change in Lp-PLA2 and its association wit...


    pub_type: 杂志文章


    authors: Li J,Wang H,Tian J,Chen B,Du F

    更新日期:2018-07-01 00:00:00

  • Effectiveness of paroxetine in the treatment of poststroke depression.

    abstract::This study retrospectively investigated the effectiveness of paroxetine for the treatment of poststroke depression (PSD).Seventy patient cases with PSD were included in this study, and were assigned to an intervention group and a control group equally. All patients received routine treatment in both groups. Additional...


    pub_type: 杂志文章


    authors: Ma C,Li P

    更新日期:2018-07-01 00:00:00

  • Influenza A with hemorrhagic shock and encephalopathy syndrome in an adult: A case report.

    abstract:INTRODUCTION:Hemorrhagic shock and encephalopathy syndrome (HSES) is a type of acute encephalopathy mainly seen in infants. It is a syndrome encompassing an onset of high fever, disturbance of consciousness, convulsion, and shock that rapidly progresses to watery diarrhea and liver and renal dysfunctions. It is extreme...


    pub_type: 杂志文章


    authors: Fukuda M,Yoshida T,Moroki M,Hirayu N,Nabeta M,Nakamura A,Uzu H,Takasu O

    更新日期:2019-04-01 00:00:00

  • The association between CCND1 G870A polymorphism and colorectal cancer risk: A meta-analysis.

    abstract:BACKGROUND:CyclinD1 (CCND1) is a key cell cycle regulatory protein. A large number of epidemiological studies have assessed the potential correlation between the CCND1 G870A polymorphism and the risk of colorectal cancer (CRC), but their findings have been inconsistent. To obtain a more precise understanding of the ass...


    pub_type: 杂志文章,meta分析,评审


    authors: Xie M,Zhao F,Zou X,Jin S,Xiong S

    更新日期:2017-10-01 00:00:00

  • Concomitant severe influenza and cryptococcal infections: A case report and literature review.

    abstract::Concomitant influenza and cryptococcal infections are rare. Herein, we describe an unusual case of an avian influenza A (H7N9) infection with several severe mixed bacterial infections and systemic super-infection with Cryptococcus neoformans presenting as ventilator-associated pneumonia (VAP) and bloodstream infection...


    pub_type: 杂志文章,评审


    authors: Huang J,Li H,Lan C,Zou S,Zhang H,Wang X,Weng H

    更新日期:2019-05-01 00:00:00

  • Novel strength test battery to permit evidence-based paralympic classification.

    abstract::Ordinal-scale strength assessment methods currently used in Paralympic athletics classification prevent the development of evidence-based classification systems. This study evaluated a battery of 7, ratio-scale, isometric tests with the aim of facilitating the development of evidence-based methods of classification. T...


    pub_type: 杂志文章


    authors: Beckman EM,Newcombe P,Vanlandewijck Y,Connick MJ,Tweedy SM

    更新日期:2014-06-01 00:00:00

  • Onodi cell mucocele causing isolated trochlear nerve palsy: A case report.

    abstract:RATIONALE:Acquired vertical diplopia is commonly observed in trochlear nerve palsy, often resulting from blunt head trauma or vascular problems. It is rarely caused by tumorous conditions or space occupying lesion. We report the first case of Onodi cell mucocele causing isolated trochlear nerve palsy. PATIENT CONCERNS...


    pub_type: 杂志文章


    authors: Kwon KW,Oh JS,Kim JW,Yoo RE,Kang JG

    更新日期:2019-05-01 00:00:00

  • Effect of cancer characteristics and oncological outcomes associated with laparoscopic colorectal resection converted to open surgery: A meta-analysis.

    abstract:BACKGROUND:Although laparoscopic colorectal cancer resection is an oncologically safe procedure equivalent to open resection,the effects of conversion of a laparoscopic approach to an open approach remain unclear.This study evaluated the cancer characteristic and oncological outcomes associated with conversion of lapar...


    pub_type: 杂志文章


    authors: Wu B,Wang W,Hao G,Song G

    更新日期:2018-12-01 00:00:00

  • Efficacy of acid suppression therapy in gastroesophageal reflux disease-related chronic laryngitis.

    abstract:BACKGROUND:This research aims to assess the response to acid suppression therapy in gastroesophageal reflux disease (GERD)-related chronic laryngitis (CL). METHODS:Data were extracted from Web of Knowledge, Embase, and PubMed for English language article published up to March 2016. Pooled overall response rate (ORR) r...


    pub_type: 杂志文章,meta分析,评审


    authors: Yang Y,Wu H,Zhou J

    更新日期:2016-10-01 00:00:00

  • Integrated analysis of a competing endogenous RNA network reveals key lncRNAs as potential prognostic biomarkers for human bladder cancer.

    abstract::Human bladder cancer (BCa) is one of the most commonly diagnosed malignancies worldwide. It has high recurrence rates and low-grade malignancy, thus representing an important public health concern. An increasing number of studies suggest that long-noncoding RNAs (lncRNAs) play important roles in various biological pro...


    pub_type: 杂志文章


    authors: Zhu N,Hou J,Wu Y,Liu J,Li G,Zhao W,Ma G,Chen B,Song Y

    更新日期:2018-08-01 00:00:00

  • Barbed versus conventional 2-layer continuous running sutures for laparoscopic vaginal cuff closure.

    abstract::We compared results using unidirectional barbed sutures and conventional sutures for vaginal cuff closure during total laparoscopic hysterectomy (TLH).The electronic medical records and surgical videos of 170 patients who underwent TLH between January 2013 and March 2015 at Uijeong-bu St. Mary's Hospital of Catholic U...


    pub_type: 杂志文章


    authors: Kim JH,Byun SW,Song JY,Kim YH,Lee HJ,Park TC,Lee KH,Hur SY,Park JS,Lee SJ

    更新日期:2016-09-01 00:00:00

  • Restrictive allogeneic blood transfusion strategy in patients with extremity bone sarcomas.

    abstract::Allogeneic blood transfusions (ABTs) are common in patients with cancer. The present study investigated the safety of a restrictive ABT strategy in patients with extremity sarcomas.Patients who underwent operations for extremity bone sarcomas between May 2008 and November 2018 were retrospectively reviewed. Clinical o...


    pub_type: 杂志文章


    authors: Park JH,Hong SH,Jang WY

    更新日期:2019-12-01 00:00:00

  • Image quality of mixed convolution kernel in thoracic computed tomography.

    abstract::The mixed convolution kernel alters his properties geographically according to the depicted organ structure, especially for the lung. Therefore, we compared the image quality of the mixed convolution kernel to standard soft and hard kernel reconstructions for different organ structures in thoracic computed tomography ...


    pub_type: 杂志文章


    authors: Neubauer J,Spira EM,Strube J,Langer M,Voss C,Kotter E

    更新日期:2016-11-01 00:00:00

  • A clinical prediction rule for acute bilirubin encephalopathy in neonates with extreme hyperbilirubinemia: A retrospective cohort study.

    abstract::To establish a clinical prediction rule for acute bilirubin encephalopathy (ABE) in term/near-term neonates with extreme hyperbilirubinemia.A retrospective cohort study was conducted between January 2015 and December 2018. Six hundred seventy-three out of 26,369 consecutive neonates with extreme hyperbilirubinemia wer...


    pub_type: 杂志文章


    authors: Zhang F,Chen L,Shang S,Jiang K

    更新日期:2020-02-01 00:00:00

  • Intravenous versus topical tranexamic acid in primary total hip replacement: A meta-analysis.

    abstract:BACKGROUND:As the prevalence of total hip arthroplasty (THA) is increasing, it is usually associated with considerable blood loss. Tranexamic acid (TXA) has been reported to reduce perioperative blood loss in hip joint arthroplasty. But the best route of TXA administration continues to be controversial. So, we conducte...


    pub_type: 杂志文章,meta分析


    authors: Zhang P,Liang Y,Chen P,Fang Y,He J,Wang J

    更新日期:2016-12-01 00:00:00

  • Differential Clinical Impact of Ascites in Cirrhosis and Idiopathic Portal Hypertension.

    abstract::Cirrhosis and idiopathic portal hypertension (IPH) are 2 major diseases showing portal hypertension. However, characteristics and outcomes of IPH with ascites have not yet been determined. The aim of the study was to examine the influence of ascites on the long-term clinical course of IPH.This observational study comp...


    pub_type: 杂志文章


    authors: Maruyama H,Kondo T,Sekimoto T,Yokosuka O

    更新日期:2015-07-01 00:00:00

  • Enhanced recovery program versus traditional care after hepatectomy: A meta-analysis.

    abstract::To assess the safety and efficacy of enhanced recovery after surgery (ERAS) as compared with the traditional care in patients undergoing liver surgery and optimization of enhanced recovery programs.Literature, until August 2016, was searched to identify the comparative studies evaluating preoperative hospital stay tim...


    pub_type: 杂志文章,meta分析


    authors: Li L,Chen J,Liu Z,Li Q,Shi Y

    更新日期:2017-09-01 00:00:00

  • Computed tomography portography of patients with cirrhosis with normal body mass index: Comparison between low-tube-voltage CT with low contrast agent dose and conventional CT.

    abstract::This study is to investigate the computed tomography (CT) image quality of the low- tube-voltage protocol with low contrast agent dose.CT portography was performed in 118 cirrhosis patients with body mass index (BMI) less than 25 kg/m under 2 protocols: Protocol A, tube voltage of 90 kVp/395 mAs and contrast agent dos...


    pub_type: 杂志文章,随机对照试验


    authors: Liu S,Sheng H,Shi H,Li W,Fan J,He J,Sun H

    更新日期:2018-11-01 00:00:00

  • Chinese patent medicine (Jinlong Capsule) for gastric cancer: Protocol for a systematic review and meta-analysis.

    abstract:BACKGROUND:JLC has been widely applied as a promising adjunctive drug for GC. However, the exact effects and safety of JLC have yet to be systematically investigated. We aimed to summarize the efficacy and safety of JLC for the treatment of advanced GC through the meta-analysis, in order to provide scientific reference...


    pub_type: 杂志文章


    authors: Li J,Han B,Sun G,Zheng Z,Mu Y,Chi J

    更新日期:2020-06-05 00:00:00

  • Prognostic role of galectins expression in patients with hepatic cancer: A meta-analysis.

    abstract:OBJECTIVE:The objective of this study was to illustrate the prognostic value of diversified galectins in patients with hepatic cancer via meta-analysis. METHODS:We conducted a systematic search on PubMed, Embase, The Cochrane Library, Web of Science, the Chinese National Knowledge Infrastructure (CNKI) database, and W...


    pub_type: 杂志文章,meta分析


    authors: Shao Q,He J,Chen Z,Wu C

    更新日期:2020-04-01 00:00:00

  • Traditional Chinese medicine for management of recurrent and refractory Crohn disease: A case report.

    abstract:INTRODUCTION:Crohn disease (CD) is a chronic relapsing systemic inflammatory disease afflicting the gastrointestinal system with a high morbidity. There has been increasing clinical interest in traditional Chinese medicine (TCM) treatment for CD. This report aims to present patient outcome of therapeutic management usi...


    pub_type: 杂志文章


    authors: Lai H,Wang K,Dong Q,Zhu X,Li X,Qi S

    更新日期:2019-04-01 00:00:00

  • Therapeutic effectiveness of neuromuscular electrical stimulation for treating patients with chronic low back pain.

    abstract::This retrospective study investigated the effectiveness and safety of neuromuscular electrical stimulation (NMES) for patients with chronic low back pain (CLBP).A total of 72 patients with CLBP were included in this retrospective study. All patients received usual care, and were assigned to a NMES group (n = 36) and a...


    pub_type: 杂志文章


    authors: Guo P,Wang JW,Tong A

    更新日期:2018-11-01 00:00:00

  • Which is the better timing between embolization and surgery for hypervascular spinal tumors, the same day or the next day?: A retrospective comparative study.

    abstract::Previous series presented the timing between embolization and surgery in a wide range on the basis of their experience rather than supportive data. And comparative studies were limited to small samples. In addition, there is no study publishing the timing by considering both safety and efficacy of embolization. The ai...


    pub_type: 杂志文章


    authors: Tang B,Ji T,Guo W,Tang X,Jin L,Dong S,Xie L

    更新日期:2018-06-01 00:00:00

  • Relationship between ataxia and inferior cerebellar peduncle injury in patients with cerebral infarct.

    abstract:INTRODUCTION:The inferior cerebellar peduncle (ICP) is a major neural tract in the cerebellum and is involved in coordination of movement and proprioceptive; therefore, ICP injury can be accompanied by poor coordination of movement, including ataxia. In this study, using diffusion tensor tractography (DTT), we investig...


    pub_type: 杂志文章


    authors: Jang SH,Lee HD

    更新日期:2020-02-01 00:00:00

  • Transmissibility and familiality of NEO personality dimensions in a sample of Korean families with schizophrenia.

    abstract::Categorical syndromes such as schizophrenia may represent complexes of many continuous psychological structural phenotypes along several dimensions of personality development/degeneration. The present study investigated the heritability and familiality of Neuroticism-Extraversion-Openness to experience (NEO) personali...


    pub_type: 杂志文章


    authors: Kim SY,Lee BD,Park JM,Lee YM,Moon E,Jeong HJ,Chung YI

    更新日期:2018-02-01 00:00:00

  • Prospective and comparative study of paroxysmal nocturnal hemoglobinuria patients treated or not by eculizumab: Focus on platelet extracellular vesicles.

    abstract::Thrombosis are severe complications of paroxysmal nocturnal hemoglobinuria (PNH), effectively reduced by eculizumab. Extracellular vesicles (EVs) may play a central role. The objective of this study was to assess the procoagulant activity of plasma isolated from PNH patients (treated or not by eculizumab) and to quant...


    pub_type: 杂志文章


    authors: Devalet B,Wannez A,Bailly N,Alpan L,Gheldof D,Douxfils J,Bihin B,Chatelain B,Dogné JM,Chatelain C,Mullier F

    更新日期:2019-07-01 00:00:00

  • Development and validation of a mortality risk model for pediatric sepsis.

    abstract::Pediatric sepsis is a burdensome public health problem. Assessing the mortality risk of pediatric sepsis patients, offering effective treatment guidance, and improving prognosis to reduce mortality rates, are crucial.We extracted data derived from electronic medical records of pediatric sepsis patients that were colle...


    pub_type: 杂志文章


    authors: Chen M,Lu X,Hu L,Liu P,Zhao W,Yan H,Tang L,Zhu Y,Xiao Z,Chen L,Tan H

    更新日期:2017-05-01 00:00:00

  • The Guillain-Barré syndrome: pulmonary-neurologic correlations.

    abstract::In a retrospective analysis of 40 hospitalized patients with the Guillain-Barré syndrome (GBS), we related the use and outcome of assisted ventilation to specific quantitative details of the neurologic illness. Two patients had an unusually prolonged course: they were ventilated for 374 and 396 days before successful ...


    pub_type: 杂志文章


    authors: Sunderrajan EV,Davenport J

    更新日期:1985-09-01 00:00:00

  • Reduning injection combined with western medicine for pneumonia: A protocol for systematic review and meta-analysis.

    abstract:BACKGROUND:Pneumonia is a common respiratory disease. In severe cases, it can induce cardiovascular disease and even life-threatening. In particular, pneumonia caused by the new coronavirus (SARS-CoV-2) that broke out at the end of 2019 has seriously affected the health of people in all countries. In recent years, it h...


    pub_type: 杂志文章,meta分析


    authors: Cao C,Zhen Z,Kuang S,Xu T

    更新日期:2020-10-23 00:00:00

  • Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1, and -DQA1 allelic profiles distinguish European American patients with different myositis autoantibodies.

    abstract::The idiopathic inflammatory myopathies (IIM) are systemic connective tissue diseases defined by chronic muscle inflammation and weakness associated with autoimmunity. We have performed low to high resolution molecular typing to assess the genetic variability of major histocompatibility complex loci (HLA-A, -B, -Cw, -D...


    pub_type: 杂志文章


    authors: O'Hanlon TP,Carrick DM,Targoff IN,Arnett FC,Reveille JD,Carrington M,Gao X,Oddis CV,Morel PA,Malley JD,Malley K,Shamim EA,Rider LG,Chanock SJ,Foster CB,Bunch T,Blackshear PJ,Plotz PH,Love LA,Miller FW

    更新日期:2006-03-01 00:00:00