Influence of surgical margins on overall survival after resection of intrahepatic cholangiocarcinoma: A meta-analysis.

Abstract:

BACKGROUND:Surgical resection is shown to present the best chance of cure in the treatment of intrahepatic cholangiocarcinoma (ICC). However, the appropriate length of the negative margin remains unclear. The aim of the present meta-analysis was to investigate whether a clear margin of 10 mm or more (≥10 mm) conferred any survival benefit over a margin of less than 10 mm (<10 mm) in patients with resected ICC. METHODS:The meta-analysis was conducted in adherence with the PRISMA guidelines. PubMed, Web of Science, EMBASE, and the Cochrane Library were systematically searched to identify eligible studies published in English from the initiation of the databases to February 2016. Overall survival rates were pooled by using the hazard ratio and the corresponding 95% confidence interval (CI). Random-effect models were utilized because of between-study heterogeneity. RESULTS:Six studies (eight cohorts) reporting on 712 patients were analyzed: 269 (37.80%) were in the 10 mm or more negative margin group, and 443 (62.20%) were in the less than 10 mm negative margin group. The pooled hazard ratio for the less than 10 mm group was found to be 1.59 (95% CI: 1.09-2.32) when this group was compared with the 10 mm or more group (reference), with moderate between-study heterogeneity (I = 45.30%, P = 0.07). Commensurate results were identified by sensitivity analysis. CONCLUSION:The result of this meta-analysis suggests a long-term survival (overall survival) advantage for negative margins of 10 mm or more in comparison with negative margins less than 10 mm for patients undergoing surgical resection of ICC.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Tang H,Lu W,Li B,Meng X,Dong J

doi

10.1097/MD.0000000000004621

subject

Has Abstract

pub_date

2016-08-01 00:00:00

pages

e4621

issue

35

eissn

0025-7974

issn

1536-5964

pii

00005792-201608300-00040

journal_volume

95

pub_type

杂志文章,meta分析,评审

相关文献

MEDICINE文献大全
  • Economic and health impacts of infectious diseases in China: A protocol for systematic review and meta analysis.

    abstract:BACKGROUND:A worldwide concern has been raised that novel infectious diseases may outbreak rapidly with a limited response time due to globalization. Severe Acute Respiratory Syndrome, influenza A, Avian Influenza Virus, and Corona Virus Disease 2019 are acute respiratory diseases that have been affected by the movemen...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000021249

    authors: Li M,Fan D,Wang X

    更新日期:2020-07-24 00:00:00

  • Misinterpretation of carbon dioxide monitoring because of deadspace of heat and moisture exchanger with a filter in pediatric anesthesia: A case report.

    abstract:RATIONALE:When patients are intubated and treated with mechanical ventilation, the upper respiratory tract is bypassed by the flow of dry and cold air. To prevent disturbances of airway homeostasis, a heat and moisture exchanger filter (HMEF) has been applied to breathing circuit. PATIENT CONCERNS:A 4-month-old male i...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012158

    authors: Lee JE,Kim JH,Kim SO

    更新日期:2018-08-01 00:00:00

  • Risk factors of the postoperative 30-day readmission of gastric cancer surgery after discharge: A PRISMA-compliant systematic review and meta-analysis.

    abstract:BACKGROUND:Readmission is a common postoperative adverse event. This study aimed to analyze potential risk factors for the incidence of postoperative 30-day readmission after discharge for gastric cancer patients with surgical treatment. METHODS:Those studies that reported the risk factors of gastric cancer patients w...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000014639

    authors: Wu WW,Zhang WH,Zhang WY,Yang L,Deng XQ,Zhu T

    更新日期:2019-03-01 00:00:00

  • Extrapleural solitary fibrous tumor in thymic area: A case report.

    abstract:RATIONALE:Solitary fibrous tumor (SFT) is a rare benign soft tissue mesenchymal neoplasm. There have been a few reports of extrapleural SFTs although it can occur anywhere in the body. PATIENT CONCERNS:A 30-year-old male presented with an anterior neck mass since one month. DIAGNOSES:Based on physical and radiologic ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000006995

    authors: Jung EK,Kim YY,Lee DH,Lee KH,Lee JK

    更新日期:2017-05-01 00:00:00

  • Risk factors associated with hepatic osteopathy in HBV related cirrhosis measured by liver stiffness: An Observational study.

    abstract::To investigate the differences in bone mineral density between patients with liver cirrhosis and healthy control, and to analyze the risk factors of hepatic osteoporosis in patients with HBV related liver cirrhosis.A total of 189 patients with liver cirrhosis and 207 health controls were enrolled. The bone mineral den...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000016628

    authors: Zhang W,Gong H,Su Z,Zhang X,Cao S

    更新日期:2019-08-01 00:00:00

  • Effect of different doses of intravenous oxycodone and fentanyl on intubation-related hemodynamic responses: A prospective double-blind randomized controlled trial (CONSORT).

    abstract:BACKGROUND:Intubation using direct laryngoscopy is a risky and painful procedure that is associated with undesirable hemodynamic changes such as tachycardia, hypertension, and arrhythmia. Recently, intravenous oxycodone was introduced and used for the control of acute postoperative pain and to attenuate intubation-rela...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0000000000015509

    authors: Koh GH,Jung KT,So KY,Seo JS,Kim SH

    更新日期:2019-05-01 00:00:00

  • The effect of Baduanjin exercise on the quality of life in patients recovering from COVID-19: A protocol for systematic review and meta-analysis.

    abstract:BACKGROUND:Since the outbreak of COVID-19, the number of COVID-19 patients has been on the rise. With the improvement of diagnosis and treatment level in various countries, more and more patients have recovered. Baduanjin exercise is a traditional Chinese health care method with a long history, easy-to-learn, and remar...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000022229

    authors: Ma Q,Yang Z,Zhu F,Chen H,Yang H,Wang S

    更新日期:2020-09-11 00:00:00

  • Comparison of 2 curative treatment options for very early hepatocellular carcinoma: Efficacy, recurrence pattern, and retreatment.

    abstract::Curative treatments for very early-stage hepatocellular carcinoma (HCC), defined as single HCC with a maximum diameter of <2 cm in patients with well-preserved liver function, consist of surgical resection or radiofrequency ablation (RFA). In this retrospective study, we compared the efficacy of both treatments in 154...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000016279

    authors: Kim TH,Chang JM,Um SH,Jee H,Lee YR,Lee HA,Yim SY,Han NY,Lee JM,Choi HS,Kim ES,Yu YD,Keum B,Kim MJ,An H,Park BJ,Seo YS,Kim DS,Yim HJ,Cho SB,Jeen YT,Lee HS,Chun HJ,Kim YH,Kim CD

    更新日期:2019-06-01 00:00:00

  • Association of polymorphisms in STRA6 gene with gestational diabetes mellitus in a Chinese Han population.

    abstract::Cell and animal experiments have found that in addition to being a retinol transporter, Stimulated by Retinoic Acid 6 (STRA6) also functions as a surface signaling receptor by which retinol regulates insulin responses. Several studies revealed that the STRA6 gene may contribute to the pathogenesis of type 2 diabetes m...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014885

    authors: Hu S,Yan J,You Y,Yang G,Zhou H,Li X,Liao X,Tan H

    更新日期:2019-03-01 00:00:00

  • Oral contraception following abortion: A systematic review and meta-analysis.

    abstract::Oral contraceptives (OCs) following induced abortion offer a reliable method to avoid repeated abortion. However, limited data exist supporting the effective use of OCs postabortion. We conducted this systematic review and meta-analysis in the present study reported immediate administration of OCs or combined OCs post...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000003825

    authors: Che Y,Liu X,Zhang B,Cheng L

    更新日期:2016-07-01 00:00:00

  • Efficacy and Safety of Celecoxib Therapy in Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials.

    abstract::Osteoarthritis (OA) is the most common form of arthritis in older individuals and is among the most prevalent and disabling chronic conditions worldwide.We conducted a meta-analysis to determine the efficacy and safety of celecoxib, a cyclooxygenase-2 (COX-2) inhibitor in the treatment of osteoarthritis. Studies were ...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000003585

    authors: Xu C,Gu K,Yasen Y,Hou Y

    更新日期:2016-05-01 00:00:00

  • Acupuncture combined Bobath approach for limbs paralysis after hypertensive intracerebral hemorrhage: A protocol for a systematic review.

    abstract:BACKGROUND:Previous studies have reported that acupuncture combined Bobath approach (BA) can be used to treat limbs paralysis (LP) after hypertensive intracerebral hemorrhage (HICH) effectively. However, no systematic review has explored its effectiveness and safety for LP following HICH. In this systematic review, we ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014750

    authors: Song GF,Li X,Feng Y,Yu CH,Lian XY

    更新日期:2019-03-01 00:00:00

  • Different patterns in mental rotation of facial expressions in complex regional pain syndrome patients.

    abstract::Although facial pain expressions are considered to be the most visible pain behaviors, it is known that the association between pain intensity and facial pain expression is weak for chronic pain. The authors hypothesized that the facial pain expressiveness was altered in chronic pain and investigated it with a mental ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000007990

    authors: Lee WJ,Choi SH,Jang JH,Moon JY,Kim YC,Noh E,Shin JE,Shin H,Kang DH

    更新日期:2017-09-01 00:00:00

  • Modified 2-port laparoscopic herniorrhaphy with Kirschner wire in children: A retrospective review.

    abstract:BACKGROUND:Pediatric inguinal hernia is one of the most common diseases in children, and laparoscopy is the main surgical method. This study aims to evaluate the efficacy of a new modified 2-port laparoscopic herniorrhaphy with Kirschner wire (TLHK) for inguinal hernia in children. METHODS:A total of 5304 children wit...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012790

    authors: Cao Z,Chen J,Li Z,Li G

    更新日期:2018-10-01 00:00:00

  • Prognostic value of serum zinc levels in patients with acute HC/zinc chloride smoke inhalation.

    abstract::Hexachloroethane (HC)/zinc chloride (ZnCl, smoke bomb) exposure in the military setting results in lung injury which is uncommon and has been rarely described in previous studies. The aim of this study is to investigate the correlation between the serum zinc in patients with HC/ZnCl smoke inhalation lung injury and di...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000008156

    authors: Xie F,Zhang X,Xie L

    更新日期:2017-09-01 00:00:00

  • Salvage pancreaticoduodenectomy after complete response to chemoradiotherapy for a previously unresectable pancreatic adenosquamous carcinoma: a case report.

    abstract::Pancreatic cancer is known for its typically late presentation and poor survival rates, with overall 5-year survival of less than 5%. The role of chemotherapy alone or with radiotherapy in the management of locally advanced tumors continues to be an area of debate.We report a case of locally advanced, pancreatic adeno...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000000499

    authors: Elias A,Chatzizacharias NA,Xanthis A,Corrie P,Davies S,Brais RJ,Jamieson NV,Praseedom RK,Huguet E,Harper SJF,Jah A

    更新日期:2015-02-01 00:00:00

  • Pretreatment elevated serum lactate dehydrogenase as a significant prognostic factor in malignant mesothelioma: A meta-analysis.

    abstract:BACKGROUND:Lactate dehydrogenase (LDH) as a hypoxia-regulator plays a vital role in alternative metabolic pathways of cancer cells. Numerous studies have assessed the prognostic value of elevated pretreatment LDH in malignant mesothelioma (MM). However, the results have been largely inconsistent. Hence, the aim of curr...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000005706

    authors: Zhuo Y,Lin L,Wei S,Zhang M

    更新日期:2016-12-01 00:00:00

  • Transurethral procedures in the treatment of benign prostatic hyperplasia: A systematic review and meta-analysis of effectiveness and complications.

    abstract:BACKGROUND:With the progress of surgical techniques and instruments, various minimally invasive surgical therapies were developed to treat benign prostatic hyperplasisa (BPH). However, the efficacy and safety of different transurethral procedures for the treatment of BPH are still undefined. METHOD:A systematic search...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000013360

    authors: Sun F,Sun X,Shi Q,Zhai Y

    更新日期:2018-12-01 00:00:00

  • S-1 and Cisplatin With or Without Nimotuzumab for Patients With Untreated Unresectable or Metastatic Gastric Cancer: A Randomized, Open-Label Phase 2 Trial.

    abstract::This open-label, randomized phase II trial was performed to compare the efficacy and safety of nimotuzumab plus S-1 and cisplatin (NCS) versus S-1 and cisplatin (CS) alone in patients with untreated unresectable or metastatic gastric cancer in the first-line setting. Eligible participants were randomly assigned (1:1) ...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0000000000000958

    authors: Du F,Zheng Z,Shi S,Jiang Z,Qu T,Yuan X,Sun Y,Song Y,Yang L,Zhao J,Wang J,Chi Y

    更新日期:2015-06-01 00:00:00

  • Acupuncture for anxiety: A protocol for a systematic review of controlled trials.

    abstract:BACKGROUND:Acupuncture has been widely, used in Asian countries since the Yuan Dynasty in China. Moreover, acupuncture has been reported to exhibit anti-allergy effects in many clinical trials. This systematic review will assess the effectiveness, and safety of acupuncture for anxiety treatment. METHODS:Eleven databas...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010266

    authors: Choi SY,Kim GW

    更新日期:2018-04-01 00:00:00

  • Concurrent treatment with rituximab and plasma exchange for severe refractory granulomatosis with polyangiitis: A case report.

    abstract:RATIONALE:Rituximab is recommended to induce remission of severe granulomatosis with polyangiitis (GPA). Plasma exchange (PE) may be considered in the setting of rapidly progressive glomerulonephritis (RPGN) with a serum creatinine increase of more than 5.6 mg/dl or diffuse alveolar hemorrhage (DAH). However, there are...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000018139

    authors: Song R,Chung SW,Lee YA

    更新日期:2019-12-01 00:00:00

  • Effect of high-quality nursing on alleviating depression and anxiety in patients with thyroid cancer during perioperative period: A protocol for systematic review.

    abstract:BACKGROUND:This study will assess the effect of high-quality nursing (HQN) on alleviating depression and anxiety (DA) in patients with thyroid cancer (TC) during perioperative period (PPP). METHODS:We will search the following electronic databases (MEDLINE, EMBASE, PsycINFO, Cochrane Library, CINAHL, Web of Science, C...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000023018

    authors: Cui Y,Li YX

    更新日期:2020-11-06 00:00:00

  • Prognostic value of serum albumin for patients with acute aortic dissection: A retrospective cohort study.

    abstract::Serum albumin (SA) is associated with inflammation and thrombosis, which are involved in acute aortic dissection (AAD). Our aim was to investigate the effect of SA level on survival in patients with AAD.We analyzed 777 patients with AAD. The patients were divided into hypoalbuminemia and non-hypoalbuminemia groups acc...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014486

    authors: Gao Y,Li D,Cao Y,Zhu X,Zeng Z,Tang L

    更新日期:2019-02-01 00:00:00

  • Not only for melanoma. Subcutaneous pseudoprogression in lung squamous-cell carcinoma treated with nivolumab: A case report.

    abstract:RATIONALE:Pseudoprogression, that is, initial tumor growth followed by subsequent tumor regression, has been well described for immunomodulation therapy in melanoma patients. This phenomenon is not well defined in lung cancer. Nivolumab, an anti-PD-1 monoclonal antibody, was recently approved for nonsmall cell lung can...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005951

    authors: Sarfaty M,Moore A,Dudnik E,Peled N

    更新日期:2017-01-01 00:00:00

  • Delayed Intracerebral Hemorrhage Secondary to Ventriculoperitoneal Shunt: A Case Report and Literature Review.

    abstract::The ventriculoperitoneal (VP) shunt is a routine procedure for cerebrospinal fluid (CSF) diversion, and is associated with many complications. A delayed hemorrhage after the VP shunt surgery, however, is quite rare. In this study, we report a case involving late-onset hemorrhage. The 67-year-old male patient with a hi...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000002029

    authors: Ma L,Chen YL,Yang SX,Wang YR

    更新日期:2015-11-01 00:00:00

  • No association between abortion and risk of breast cancer among nulliparous women: Evidence from a meta-analysis.

    abstract:BACKGROUND:Various epidemiological studies have demonstrated the association between abortion and risk of breast cancer among nulliparous women; however, results remain inconclusive. This meta-analysis assessed the association based on previous studies. METHODS:PubMed, EMBase, China National Knowledge Infrastructure, ...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000020251

    authors: Tong H,Wu Y,Yan Y,Dong Y,Guan X,Liu Y,Lu Z

    更新日期:2020-05-01 00:00:00

  • Clinical characteristics of dysphagic stroke patients with salivary aspiration: A STROBE-compliant retrospective study.

    abstract::The aim of this study was to evaluate the correlation between radionuclide salivagram findings and clinical characteristics in stroke patient with swallowing difficulty.In this study, dysphagic stroke patients who had undergone both a radionuclide salivagram and videofluoroscopic swallowing study (VFSS) were included ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014977

    authors: Yu KJ,Park D

    更新日期:2019-03-01 00:00:00

  • Poikilothermia in man: pathophysiology and clinical implications.

    abstract::Poikilothermia, the inability to maintain a constant core temperature independent of ambient temperature, markedly influences both the mental and physical function of affected patients; furthermore, prolonged hypothermia can induce numerous complications. To establish the pathophysiology of thermoregulation underlying...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/00005792-199107000-00003

    authors: MacKenzie MA,Hermus AR,Wollersheim HC,Pieters GF,Smals AG,Binkhorst RA,Thien T,Kloppenborg PW

    更新日期:1991-07-01 00:00:00

  • A Retrospective Cohort Study Comparing Stroke Recurrence Rate in Ischemic Stroke Patients With and Without Acupuncture Treatment.

    abstract::Little was known about the effects of acupuncture on stroke recurrence. The aim of this study is to investigate whether ischemic stroke patients receiving acupuncture treatment have a decreased risk of stroke recurrence. A retrospective cohort study of 30,058 newly diagnosed cases of ischemic stroke in 2000 to 2004 wa...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000001572

    authors: Shih CC,Liao CC,Sun MF,Su YC,Wen CP,Morisky DE,Sung FC,Hsu CY,Lin JG

    更新日期:2015-09-01 00:00:00

  • The role of real-time elastography-targeted biopsy in the detection and diagnosis of prostate cancer: A systematic review and meta-analysis.

    abstract:BACKGROUND:The role of real-time elastography (RTE)-targeted biopsy in the detection and diagnosis of prostate cancer (PCa) remains controversial. METHODS:We searched Medline, Embase, and Cochrane Library from inception to July 31, 2017 and used the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool to ...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000010220

    authors: Tu X,Qiu S,Chang T,Jin K,Bao Y,Yang L,Wei Q

    更新日期:2018-03-01 00:00:00