Abstract:
PURPOSE:We have developed iodine-supported titanium implants that suppress microbial activities and conducted in vivo and in vitro studies to determine their antimicrobial properties. METHODS:The implants were Ti-6Al-4 V titanium implants either untreated (Ti), treated with oxide film on the Ti surface by anodization (Ti-O), or treated with an iodine coating on oxidation film (Ti-I). The strain of bacteria used in this study was Gram-positive Staphylococcus aureus strain ATCC 25923. We analyzed the antibacterial attachment effects in vivo by using rats. The attachment bacteria on the implant surface were evaluated using a spread-plate method assay. A biofilm study was performed in vitro. The biofilm formed after bacterial attachment was qualitatively studied with fluorescence microscopy (FM) and scanning electron microscopy (SEM). Also, the formed biofilm was quantitatively studied with a spread-plate method assay. RESULTS:In vivo analysis of antimicrobial attachment effects showed that the mean viable bacterial number was significantly lower on Ti-I than Ti or Ti-O surfaces. In the in vitro biofilm study, FM and SEM images showed thick and mature biofilm formation on Ti and Ti-O and thin, small biofilm formation on Ti-I. A quantitative biofilm analysis found a significant difference in the number of viable bacteria between Ti-I and Ti or Ti-O. CONCLUSIONS:This study showed that iodine-supported implants have a good antibacterial attachment effect and inhibit biofilm formation and growth. Iodine-supported implants may have great potential as innovative antibacterial implants that can prevent implant related infection in orthopaedic surgery.
journal_name
Int Orthopjournal_title
International orthopaedicsauthors
Inoue D,Kabata T,Ohtani K,Kajino Y,Shirai T,Tsuchiya Hdoi
10.1007/s00264-017-3477-3subject
Has Abstractpub_date
2017-06-01 00:00:00pages
1093-1099issue
6eissn
0341-2695issn
1432-5195pii
10.1007/s00264-017-3477-3journal_volume
41pub_type
杂志文章abstract:PURPOSE:Rheumatoid arthritis has been associated with poor clinical outcomes in hemiarthroplasty and unconstrained total shoulder arthroplasty. The reverse shoulder arthroplasty can be utilized to address the shortcomings of hemiarthroplasty and unconstrained total shoulder arthroplasty in the inflammatory arthritis pa...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-019-04373-3
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journal_title:International orthopaedics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00264-013-1903-8
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abstract:PURPOSES:We investigated sequential levels of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) in uncomplicated ACDF (anterior cervical discectomy and fusion) using allograft and DBM (demineralised bone matrix) for primary cervical spondylosis and/or disc herniation. To our knowledge, there has been no...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-012-1645-z
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abstract::A tentative classification of Perthes' disease according to the extent of epiphyseal and metaphyseal involvement in lateral radiographs of the hip was applied to 61 hips in 55 patients. Forty-four hips were treated by containment (Tachjian's trilateral socket hip abduction orthosis) and 17 hips were treated surgically...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/BF00266603
更新日期:1980-01-01 00:00:00
abstract::We evaluated the results of polygonal triple (Kotz) osteotomy for the treatment of acetabular dysplasia over 10 years. This study included 31 hips of 27 patients who had the Kotz osteotomy for acetabular dysplasia. The mean age was 21.5 years. We performed the original Kotz osteotomy for the first 22 hips (group I), w...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-006-0203-y
更新日期:2007-06-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-007-0477-8
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journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-019-04430-x
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abstract:BACKGROUND:AES mobile-bearing total ankle replacement was developed from the Buechel Pappas model. It was withdrawn in 2009, after identification of a higher than expected complication rate. The purpose of the current study was to analyse clinical outcomes, failures and survival of the initial series of 50 AES publishe...
journal_title:International orthopaedics
pub_type: 杂志文章
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更新日期:2017-12-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
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更新日期:1996-01-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-014-2534-4
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journal_title:International orthopaedics
pub_type: 杂志文章,评审
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abstract:PURPOSE:Although previously frozen shoulder was thought to resolve by two to three years, recent studies demonstrated the symptoms can remain for much longer. Manipulation under anaesthetic (MUA) has been shown to be successful in relieving pain and restoring function. Yet, concerns have been raised regarding its safet...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-017-3558-3
更新日期:2018-02-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-013-1993-3
更新日期:2013-10-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
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更新日期:2018-10-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-014-2416-9
更新日期:2014-12-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-015-3016-z
更新日期:2016-07-01 00:00:00
abstract::Diagnosis of avascular necrosis (AVN) of the femoral head depends on the combination of clinical symptoms and evaluation of radiographs and/or magnetic resonance imaging (MRI). To evaluate the evolution of AVN, the Ficat and the Association Research Circulation Osseous (ARCO) classification are commonly used to assess...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-007-0320-2
更新日期:2008-06-01 00:00:00
abstract:PURPOSE:Approximately 5% of patients with spinal tuberculosis will develop a severe kyphotic deformity resulting in increased potential for pain, spinal cord compression, cardiopulmonary dysfunction, costopelvic impingement and cosmetic concerns. This manuscript reviews the evaluation and surgical management of tubercu...
journal_title:International orthopaedics
pub_type: 杂志文章,评审
doi:10.1007/s00264-011-1292-9
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abstract:PURPOSE:Peri-radicular injection is a widely used procedure for treating lumbar radicular pain, but it remains unclear what types of lumbar pathologies respond well to this treatment. We aimed to investigate the efficacy of peri-radicular injection for degenerative lumbar disorders and to determine what types of pathol...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-015-2761-3
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journal_title:International orthopaedics
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00264-014-2455-2
更新日期:2015-04-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-018-4084-7
更新日期:2019-07-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-004-0577-7
更新日期:2004-10-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-012-1549-y
更新日期:2013-03-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/BF00547160
更新日期:1988-01-01 00:00:00
abstract:INTRODUCTION:Dual-mobility cups (DMC) are gaining popularity mainly for their reduced rate of dislocation following total hip arthroplasty (THA). Currently, indication for DMC use extends beyond patients with high risk of dislocation or revision THA cases. Many authors reported DMC outcomes in primary THA for all aetio...
journal_title:International orthopaedics
pub_type: 杂志文章,评审
doi:10.1007/s00264-020-04791-8
更新日期:2020-09-19 00:00:00
abstract:PURPOSE:This study investigated which of the reciprocal stimuli between articular chondrocytes (ACs) and mesenchymal stem cells (MSCs) played the more important role in enhancing cartilage matrix formation, and examined the relative importance of physical contact and soluble factors in the co-culture system. METHODS:R...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-013-1782-z
更新日期:2013-04-01 00:00:00
abstract:PURPOSE:Total hip arthroplasty (THA) is an effective procedure for developmental dysplasia of the hip (DDH); however, it is sometimes difficult to complete for severe cases because of femoral head dislocation, dysplasia of the acetabulum and the femur, disparity in limb length, soft tissue contraction, and muscular atr...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-012-1622-6
更新日期:2012-09-01 00:00:00
abstract:PURPOSE:The treatment strategy for pelvic osteolysis with a well-fixed acetabular component after total hip arthroplasty(THA) involves replacing the acetabular cup liner and femoral head, débriding osteolytic lesions, and grafting. METHODS:We investigated whether retention of a well-fixed acetabular component using th...
journal_title:International orthopaedics
pub_type: 信件
doi:10.1007/s00264-011-1372-x
更新日期:2012-05-01 00:00:00
abstract::One hundred fractures of the tibial shaft were treated by early weight-bearing in a below knee patellar tendon bearing plaster cast. The rate of union, and the range of knee and ankle motion were assessed. Ninety-five per cent had good or excellent results. This method of treatment is particularly valuable in the thir...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/BF00268506
更新日期:1989-01-01 00:00:00
abstract:PURPOSE:Several studies have reported a risk of dislocation in obese patients after total hip arthroplasty. In this study, we evaluated the interaction between obesity and dislocation by kinematic analysis using a navigation system. METHODS:The intraoperative range of motion (ROM) and postoperative impingement-free RO...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-012-1701-8
更新日期:2012-12-01 00:00:00