Widespread promoter methylation of synaptic plasticity genes in long-term potentiation in the adult brain in vivo.

abstract：BACKGROUND:Enterohemorrhagic Escherichia coli (EHEC) are zoonotic agents associated with outbreaks worldwide. Growth of EHEC strains in ground beef could be inhibited by background microbiota that is present initially at levels greater than that of the pathogen E. coli. However, how the microbiota outcompetes the patho...

journal_title：BMC genomics

authors： Galia W,Leriche F,Cruveiller S,Garnier C,Navratil V,Dubost A,Blanquet-Diot S,Thevenot-Sergentet D

更新日期：2017-08-03 00:00:00

abstract：BACKGROUND:The genus Populus includes poplars, aspens and cottonwoods, which will be collectively referred to as poplars hereafter unless otherwise specified. Poplars are the dominant tree species in many forest ecosystems in the Northern Hemisphere and are of substantial economic value in plantation forestry. Poplar h...

journal_title：BMC genomics

authors： Ralph SG,Chun HJ,Cooper D,Kirkpatrick R,Kolosova N,Gunter L,Tuskan GA,Douglas CJ,Holt RA,Jones SJ,Marra MA,Bohlmann J

更新日期：2008-01-29 00:00:00

abstract：BACKGROUND:The sequential nature of gel-based marker systems entails low throughput and high costs per assay. Commonly used marker systems such as SSR and SNP are also dependent on sequence information. These limitations result in high cost per data point and significantly limit the capacity of breeding programs to obt...

journal_title：BMC genomics

authors： Mace ES,Xia L,Jordan DR,Halloran K,Parh DK,Huttner E,Wenzl P,Kilian A

更新日期：2008-01-22 00:00:00

abstract：BACKGROUND:Thoroughbred horses are the most expensive domestic animals, and their running ability and knowledge about their muscle-related diseases are important in animal genetics. While the horse reference genome is available, there has been no large-scale functional annotation of the genome using expressed genes der...

journal_title：BMC genomics

authors： Park KD,Park J,Ko J,Kim BC,Kim HS,Ahn K,Do KT,Choi H,Kim HM,Song S,Lee S,Jho S,Kong HS,Yang YM,Jhun BH,Kim C,Kim TH,Hwang S,Bhak J,Lee HK,Cho BW

更新日期：2012-09-12 00:00:00

abstract：BACKGROUND:Matricaria recutita (German chamomile) and Chamaemelum nobile (Roman chamomile) belong to the botanical family Asteraceae. These two herbs are not only morphologically distinguishable, but their secondary metabolites - especially the essential oils present in flowers are also different, especially the terpen...

journal_title：BMC genomics

authors： Tai Y,Hou X,Liu C,Sun J,Guo C,Su L,Jiang W,Ling C,Wang C,Wang H,Pan G,Si X,Yuan Y

更新日期：2020-02-18 00:00:00

abstract：BACKGROUND:Natural contamination and anthropogenic pollution of soils are likely to be major determinants of functioning and survival of keystone invertebrate taxa. Soil animals will have both evolutionary adaptation and genetically programmed responses to these toxic chemicals, but mechanistic understanding of such is...

journal_title：BMC genomics

authors： Owen J,Hedley BA,Svendsen C,Wren J,Jonker MJ,Hankard PK,Lister LJ,Stürzenbaum SR,Morgan AJ,Spurgeon DJ,Blaxter ML,Kille P

更新日期：2008-06-03 00:00:00

abstract：BACKGROUND:An efficient signal transduction system allows a bacterium to sense environmental cues and then to respond positively or negatively to those signals; this process is referred to as taxis. In addition to external cues, the internal metabolic state of any bacterium plays a major role in determining its ability...

journal_title：BMC genomics

authors： Sharma G,Parales R,Singer M

更新日期：2018-10-19 00:00:00

abstract：BACKGROUND:Several methods have recently been developed to identify regions of the genome that have been exposed to strong selection. However, recent theoretical and empirical work suggests that polygenic models are required to identify the genomic regions that are more moderately responding to ongoing selection on com...

journal_title：BMC genomics

authors： Decker JE,Vasco DA,McKay SD,McClure MC,Rolf MM,Kim J,Northcutt SL,Bauck S,Woodward BW,Schnabel RD,Taylor JF

更新日期：2012-11-09 00:00:00

abstract：BACKGROUND:Characterizing large genomic variants is essential to expanding the research and clinical applications of genome sequencing. While multiple data types and methods are available to detect these structural variants (SVs), they remain less characterized than smaller variants because of SV diversity, complexity,...

journal_title：BMC genomics

authors： English AC,Salerno WJ,Hampton OA,Gonzaga-Jauregui C,Ambreth S,Ritter DI,Beck CR,Davis CF,Dahdouli M,Ma S,Carroll A,Veeraraghavan N,Bruestle J,Drees B,Hastie A,Lam ET,White S,Mishra P,Wang M,Han Y,Zhang F,Stankie

更新日期：2015-04-11 00:00:00

abstract：BACKGROUND:A disease-causing mutation refers to a heritable genetic change that is associated with a specific phenotype (disease). The detection of a mutation from a patient's sample is critical for the diagnosis, treatment, and prognosis of the disease. There are numerous databases and applications with which to archi...

journal_title：BMC genomics

authors： Jho S,Kim BC,Ghang H,Kim JH,Park D,Kim HM,Jung SY,Yoo KY,Kim HJ,Lee S,Bhak J

更新日期：2009-12-03 00:00:00

abstract：BACKGROUND:Mitochondria are organelles that fulfill a fundamental role in cell bioenergetics, as well as in other processes like cell signaling and death. Small non-coding RNAs (sncRNA) are now being considered as pivotal post-transcriptional regulators, widening the landscape of their diversity and functions. In mamma...

journal_title：BMC genomics

authors： Larriba E,Rial E,Del Mazo J

更新日期：2018-08-28 00:00:00

abstract：:The draft genome sequence of cattle (Bos taurus) has now been analyzed by the Bovine Genome Sequencing and Analysis Consortium and the Bovine HapMap Consortium, which together represent an extensive collaboration involving more than 300 scientists from 25 different countries. ...

journal_title：BMC genomics

authors： Tellam RL,Lemay DG,Van Tassell CP,Lewin HA,Worley KC,Elsik CG

更新日期：2009-04-24 00:00:00

abstract：BACKGROUND:About 6 million Americans suffer from heart failure and 70% of heart failure cases are caused by myocardial infarction (MI). Following myocardial infarction, increased cytokines induce two major types of macrophages: classically activated macrophages which contribute to extracellular matrix destruction and a...

journal_title：BMC genomics

authors： Wang Y,Yang T,Ma Y,Halade GV,Zhang J,Lindsey ML,Jin YF

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Cornu aspersum is a quite intriguing species from the point of view of ecology and evolution and its potential use in medical and environmental applications. It is a species of economic importance since it is farmed and used for culinary purposes. However, the genomic tools that would allow a thorough insigh...

journal_title：BMC genomics

authors： Parmakelis A,Kotsakiozi P,Kontos CK,Adamopoulos PG,Scorilas A

更新日期：2017-06-28 00:00:00

abstract：BACKGROUND:Campylobacter is the leading cause of foodborne diarrhoeal illness in humans and is mostly acquired from consumption or handling of contaminated poultry meat. In the absence of effective licensed vaccines and inhibitors, selection for chickens with increased resistance to Campylobacter could potentially redu...

journal_title：BMC genomics

authors： Psifidi A,Fife M,Howell J,Matika O,van Diemen PM,Kuo R,Smith J,Hocking PM,Salmon N,Jones MA,Hume DA,Banos G,Stevens MP,Kaiser P

更新日期：2016-04-18 00:00:00

abstract：BACKGROUND:Ubiquitination is an important post-translational modification involved in diverse biological processes. Therefore, genomewide representation of the ubiquitination system for a species is important. DESCRIPTION:SCUD is a web-based database for the ubiquitination system in Saccharomyces cerevisiae (Baker's y...

journal_title：BMC genomics

authors： Lee WC,Lee M,Jung JW,Kim KP,Kim D

更新日期：2008-09-24 00:00:00

abstract：BACKGROUND:Castor oil is the only commercial source of hydroxy fatty acid that has industrial value. The production of castor oil is hampered by the presence of the toxin ricin in its seed. Lesquerella seed also accumulates hydroxy fatty acid and is free of ricin, and thus it is being developed as a new crop for hydrox...

journal_title：BMC genomics

authors： Kim HU,Chen GQ

更新日期：2015-03-24 00:00:00

abstract：BACKGROUND:Prokaryotic translation initiation involves the proper docking, anchoring, and accommodation of mRNA to the 30S ribosomal subunit. Three initiation factors (IF1, IF2, and IF3) and some ribosomal proteins mediate the assembly and activation of the translation initiation complex. Although the interaction betwe...

journal_title：BMC genomics

authors： Omotajo D,Tate T,Cho H,Choudhary M

更新日期：2015-08-14 00:00:00

abstract：BACKGROUND:Toxin-antitoxin (TA) systems, abundant in prokaryotes, are composed of a toxin gene and its cognate antitoxin. Several toxins are implied to affect the physiological state and stress tolerance of bacteria in a population. We previously identified a chromosomally encoded hok-sok type I TA system in Erwinia am...

journal_title：BMC genomics

authors： Peng J,Triplett LR,Sundin GW

更新日期：2021-01-22 00:00:00

abstract：BACKGROUND:As consumers continue to request food products that have health advantages, it will be important for the livestock industry to supply a product that meet these demands. One such nutrient is fatty acids, which have been implicated as playing a role in cardiovascular disease. Therefore, the objective of this s...

journal_title：BMC genomics

authors： Saatchi M,Garrick DJ,Tait RG Jr,Mayes MS,Drewnoski M,Schoonmaker J,Diaz C,Beitz DC,Reecy JM

更新日期：2013-10-25 00:00:00

abstract：BACKGROUND:Though Illumina has largely dominated the RNA-Seq field, the simultaneous availability of Ion Torrent has left scientists wondering which platform is most effective for differential gene expression (DGE) analysis. Previous investigations of this question have typically used reference samples derived from cel...

journal_title：BMC genomics

authors： Lahens NF,Ricciotti E,Smirnova O,Toorens E,Kim EJ,Baruzzo G,Hayer KE,Ganguly T,Schug J,Grant GR

更新日期：2017-08-10 00:00:00

abstract：BACKGROUND:Fish scales are an important reservoir of calcium and phosphorus and together with the skin function as an integrated barrier against environmental changes and external aggressors. Histological studies have revealed that the skin and scales regenerate rapidly in fish when they are lost or damaged. In the pre...

journal_title：BMC genomics

authors： Vieira FA,Gregório SF,Ferraresso S,Thorne MA,Costa R,Milan M,Bargelloni L,Clark MS,Canario AV,Power DM

更新日期：2011-10-07 00:00:00

abstract：BACKGROUND:Chloroplasts have their own genomes, independent from nuclear genomes, that play vital roles in growth, which is a major targeted trait for genetic improvement in Populus. Angiosperm chloroplast genomes are maternally inherited, but the chloroplast' variation pattern of poplar at the single-base level during...

journal_title：BMC genomics

authors： Zhu S,Xu M,Wang H,Pan H,Wang G,Huang M

更新日期：2018-05-29 00:00:00

abstract：BACKGROUND:The main limitations in the analysis of viral metagenomes are perhaps the high genetic variability and the lack of information in extant databases. To address these issues, several bioinformatic tools have been specifically designed or adapted for metagenomics by improving read assembly and creating more sen...

journal_title：BMC genomics

authors： Vázquez-Castellanos JF,García-López R,Pérez-Brocal V,Pignatelli M,Moya A

更新日期：2014-01-18 00:00:00

abstract：BACKGROUND:The incidence of congenital heart disease (CHD) is continuously increasing among infants born alive nowadays, making it one of the leading causes of infant morbidity worldwide. Various studies suggest that both genetic and environmental factors lead to CHD, and therefore identifying its candidate genes and d...

journal_title：BMC genomics

authors： He D,Liu ZP,Chen L

更新日期：2011-12-02 00:00:00

abstract：BACKGROUND:The question of whether bacterial species objectively exist has long divided microbiologists. A major source of contention stems from the fact that bacteria regularly engage in horizontal gene transfer (HGT), making it difficult to ascertain relatedness and draw boundaries between taxa. A natural way to defi...

journal_title：BMC genomics

authors： Wright ES,Baum DA

更新日期：2018-10-03 00:00:00

abstract：BACKGROUND:Most published genome sequences are drafts, and most are dominated by computational gene prediction. Draft genomes typically incorporate considerable sequence data that are not assigned to chromosomes, and predicted genes without quality confidence measures. The current Actinidia chinensis (kiwifruit) 'Hongy...

journal_title：BMC genomics

authors： Pilkington SM,Crowhurst R,Hilario E,Nardozza S,Fraser L,Peng Y,Gunaseelan K,Simpson R,Tahir J,Deroles SC,Templeton K,Luo Z,Davy M,Cheng C,McNeilage M,Scaglione D,Liu Y,Zhang Q,Datson P,De Silva N,Gardiner SE,Bas

更新日期：2018-04-16 00:00:00

abstract：BACKGROUND:Infectious disease outbreaks form major setbacks to aquaculture production and to further development of this important sector. Cyprinid herpes virus-3 (CyHV-3) is a dsDNA virus widely hampering production of common carp (Cyprinus carpio), one of the most farmed fish species worldwide. Genetically disease re...

journal_title：BMC genomics

authors： Tadmor-Levi R,Doron-Faigenboim A,Marcos-Hadad E,Petit J,Hulata G,Forlenza M,Wiegertjes GF,David L

更新日期：2019-12-26 00:00:00

abstract：BACKGROUND:The insect order Neuroptera encompasses more than 5,700 described species. To date, only three neuropteran mitochondrial genomes have been fully and one partly sequenced. Current knowledge on neuropteran mitochondrial genomes is limited, and new data are strongly required. In the present work, the mitochondr...

journal_title：BMC genomics

authors： Negrisolo E,Babbucci M,Patarnello T

更新日期：2011-05-10 00:00:00

abstract：BACKGROUND:The SOS response is a well-known regulatory network present in most bacteria and aimed at addressing DNA damage. It has also been linked extensively to stress-induced mutagenesis, virulence and the emergence and dissemination of antibiotic resistance determinants. Recently, the SOS response has been shown to...

journal_title：BMC genomics

authors： Sanchez-Alberola N,Campoy S,Barbé J,Erill I

更新日期：2012-02-03 00:00:00