Genome-wide association and prediction of direct genomic breeding values for composition of fatty acids in Angus beef cattle.

abstract：BACKGROUND:Ashbya gossypii is a filamentous Saccharomycete used for the industrial production of riboflavin that has been recently explored as a host system for recombinant protein production. To gain insight into the protein secretory pathway of this biotechnologically relevant fungus, we undertook genome-wide analyse...

journal_title：BMC genomics

authors： Aguiar TQ,Ribeiro O,Arvas M,Wiebe MG,Penttilä M,Domingues L

更新日期：2014-12-18 00:00:00

abstract：BACKGROUND:Rhesus monkeys (Macaca mulatta) are widely-used as experimental animals in biomedical research and are closely related to other laboratory macaques, such as cynomolgus monkeys (Macaca fascicularis), and to humans, sharing a last common ancestor from about 25 million years ago. Although rhesus monkeys have be...

journal_title：BMC genomics

authors： Kim DS,Huh JW,Kim YH,Park SJ,Lee SR,Chang KT

更新日期：2010-07-12 00:00:00

abstract：BACKGROUND:The MYB superfamily is one of the most abundant transcription factor (TF) families in plants. MYB proteins include highly conserved N-terminal MYB repeats (1R, R2R3, 3R, and atypical) and various C-terminal sequences that confer extensive functions. However, the functions of most MYB genes are unknown, and h...

journal_title：BMC genomics

authors： Wang Z,Tang J,Hu R,Wu P,Hou XL,Song XM,Xiong AS

更新日期：2015-01-23 00:00:00

abstract：BACKGROUND:Precise identification of three-dimensional genome organization, especially enhancer-promoter interactions (EPIs), is important to deciphering gene regulation, cell differentiation and disease mechanisms. Currently, it is a challenging task to distinguish true interactions from other nearby non-interacting o...

journal_title：BMC genomics

authors： Zeng W,Wu M,Jiang R

更新日期：2018-05-09 00:00:00

abstract：BACKGROUND:We present here the assembly of the bovine genome. The assembly method combines the BAC plus WGS local assembly used for the rat and sea urchin with the whole genome shotgun (WGS) only assembly used for many other animal genomes including the rhesus macaque. RESULTS:The assembly process consisted of multipl...

journal_title：BMC genomics

authors： Liu Y,Qin X,Song XZ,Jiang H,Shen Y,Durbin KJ,Lien S,Kent MP,Sodeland M,Ren Y,Zhang L,Sodergren E,Havlak P,Worley KC,Weinstock GM,Gibbs RA

更新日期：2009-04-24 00:00:00

abstract：BACKGROUND:Prostaglandin E2 (PGE2) is involved in several chronic inflammatory diseases including periodontitis, which causes loss of the gingival tissue and alveolar bone supporting the teeth. We have previously shown that tumor necrosis factor alpha (TNFalpha) induces PGE2 synthesis in gingival fibroblasts. In this s...

journal_title：BMC genomics

authors： Båge T,Lindberg J,Lundeberg J,Modéer T,Yucel-Lindberg T

更新日期：2010-04-15 00:00:00

abstract：BACKGROUND:Genomic approaches provide unique opportunities to study interactions of insects with their pathogens. We developed a cDNA microarray to analyze the gene transcription profile of the lepidopteran pest Spodoptera frugiperda in response to injection of the polydnavirus HdIV associated with the ichneumonid wasp...

journal_title：BMC genomics

authors： Barat-Houari M,Hilliou F,Jousset FX,Sofer L,Deleury E,Rocher J,Ravallec M,Galibert L,Delobel P,Feyereisen R,Fournier P,Volkoff AN

更新日期：2006-06-21 00:00:00

abstract：BACKGROUND:Flammulina filiformis (previously known as Asian F. velutipes) is a popular commercial edible mushroom. Many bioactive compounds with medicinal effects, such as polysaccharides and sesquiterpenoids, have been isolated and identified from F. filiformis, but their biosynthesis and regulation at the molecular l...

journal_title：BMC genomics

authors： Chen J,Li JM,Tang YJ,Ma K,Li B,Zeng X,Liu XB,Li Y,Yang ZL,Xu WN,Xie BG,Liu HW,Guo SX

更新日期：2020-10-17 00:00:00

abstract：BACKGROUND:Several resistance traits, including the I2 resistance against tomato fusarium wilt, were mapped to the long arm of chromosome 11 of Solanum. However, the structure and evolution of this locus remain poorly understood. RESULTS:Comparative analysis showed that the structure and evolutionary patterns of the I...

journal_title：BMC genomics

authors： Wei C,Kuang H,Li F,Chen J

更新日期：2014-08-30 00:00:00

abstract：BACKGROUND:Subtractive hybridization methods are valuable tools for identifying differentially regulated genes in a given tissue avoiding redundant sequencing of clones representing the same expressed genes, maximizing detection of low abundant transcripts and thus, affecting the efficiency and cost effectiveness of sm...

journal_title：BMC genomics

authors： Fernández P,Paniego N,Lew S,Hopp HE,Heinz RA

更新日期：2003-09-30 00:00:00

abstract：BACKGROUND:Many transcripts have been generated due to the development of sequencing technologies, and lncRNA is an important type of transcript. Predicting lncRNAs from transcripts is a challenging and important task. Traditional experimental lncRNA prediction methods are time-consuming and labor-intensive. Efficient ...

journal_title：BMC genomics

authors： Xu Y,Zhao X,Liu S,Zhang W

更新日期：2020-12-17 00:00:00

abstract：BACKGROUND:Small bioinformatics databases, unlike institutionally funded large databases, are vulnerable to discontinuation and many reported in publications are no longer accessible. This leads to irreproducible scientific work and redundant effort, impeding the pace of scientific progress. RESULTS:We describe a Web-...

journal_title：BMC genomics

authors： Tan TW,Xie C,De Silva M,Lim KS,Patro CP,Lim SJ,Govindarajan KR,Tong JC,Choo KH,Ranganathan S,Khan AM

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Theileria parva is a tick-borne protozoan parasite, which causes East Coast Fever, a disease of cattle in sub-Saharan Africa. Like Plasmodium falciparum, the parasite undergoes a transient diploid life-cycle stage in the gut of the arthropod vector, which involves an obligate sexual cycle. As assessed using ...

journal_title：BMC genomics

authors： Henson S,Bishop RP,Morzaria S,Spooner PR,Pelle R,Poveda L,Ebeling M,Küng E,Certa U,Daubenberger CA,Qi W

更新日期：2012-09-23 00:00:00

abstract：BACKGROUND:One of the most fundamental and challenging tasks in bio-informatics is to identify related sequences and their hidden biological significance. The most popular and proven best practice method to accomplish this task is aligning multiple sequences together. However, multiple sequence alignment is a computing...

journal_title：BMC genomics

authors： Nguyen KD,Pan Y,Nong G

更新日期：2011-12-23 00:00:00

abstract：BACKGROUND:Foxtail millet [Setaria italica (L.) P. Beauv.], a crop of historical importance in China, has been adopted as a model crop for studying C-4 photosynthesis, stress biology and biofuel traits. Construction of a high density genetic map and identification of stable quantitative trait loci (QTL) lay the foundat...

journal_title：BMC genomics

authors： Fang X,Dong K,Wang X,Liu T,He J,Ren R,Zhang L,Liu R,Liu X,Li M,Huang M,Zhang Z,Yang T

更新日期：2016-05-04 00:00:00

abstract：BACKGROUND:The measurement of gene expression using microarray technology is a complicated process in which a large number of factors can be varied. Due to the lack of standard calibration samples such as are used in traditional chemical analysis it may be a problem to evaluate whether changes done to the microarray pr...

journal_title：BMC genomics

authors： Bruland T,Anderssen E,Doseth B,Bergum H,Beisvag V,Laegreid A

更新日期：2007-10-18 00:00:00

abstract：BACKGROUND:The introduction of genome-wide shRNA and CRISPR libraries has facilitated cell-based screens to identify loss-of-function mutations associated with a phenotype of interest. Approaches to perform analogous gain-of-function screens are less common, although some reports have utilized arrayed viral expression ...

journal_title：BMC genomics

authors： Feddersen CR,Wadsworth LS,Zhu EY,Vaughn HR,Voigt AP,Riordan JD,Dupuy AJ

更新日期：2019-06-17 00:00:00

abstract：BACKGROUND:The development of microarrays permits us to monitor transcriptomes on a genome-wide scale. To validate microarray measurements, quantitative-real time-reverse transcription PCR (Q-RT-PCR) is one of the most robust and commonly used approaches. The new challenge in gene quantification analysis is how to expl...

journal_title：BMC genomics

authors： Su LJ,Chang CW,Wu YC,Chen KC,Lin CJ,Liang SC,Lin CH,Whang-Peng J,Hsu SL,Chen CH,Huang CY

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are post-transcriptional regulators of mRNA expression and are involved in numerous cellular processes. Consequently, miRNAs are an important component of gene regulatory networks and an improved understanding of miRNAs will further our knowledge of these networks. There is a many-to-many ...

journal_title：BMC genomics

authors： Jayaswal V,Lutherborrow M,Ma DD,Yang YH

更新日期：2011-03-06 00:00:00

abstract：BACKGROUND:Tandemly arranged nuclear ribosomal DNA (rDNA), encoding 18S, 5.8S and 26S ribosomal RNA (rRNA), exhibit concerted evolution, a pattern thought to result from the homogenisation of rDNA arrays. However rDNA homogeneity at the single nucleotide polymorphism (SNP) level has not been detailed in organisms with ...

journal_title：BMC genomics

authors： Matyášek R,Renny-Byfield S,Fulneček J,Macas J,Grandbastien MA,Nichols R,Leitch A,Kovařík A

更新日期：2012-12-23 00:00:00

abstract：BACKGROUND:Oxidative stress caused by ground level ozone is a contributor to yield loss in a number of important crop plants. Soybean (Glycine max) is considered to be ozone sensitive, and current research into its response to oxidative stress is limited. To better understand the genetic response in soybean to oxidativ...

journal_title：BMC genomics

authors： Whaley A,Sheridan J,Safari S,Burton A,Burkey K,Schlueter J

更新日期：2015-06-04 00:00:00

abstract：BACKGROUND:In recent years, dozens of Arabidopsis and rice CCCH-type zinc finger genes have been functionally studied, many of which confer important traits, such as abiotic and biotic stress tolerance, delayed leaf senescence and improved plant architecture. Switchgrass (Panicum virgatum) is an important bioenergy cro...

journal_title：BMC genomics

authors： Yuan S,Xu B,Zhang J,Xie Z,Cheng Q,Yang Z,Cai Q,Huang B

更新日期：2015-02-25 00:00:00

abstract：BACKGROUND:The human zinc finger protein 191 (ZNF191) is a member of the SCAN domain family of Krüppel-like zinc finger transcription factors. ZNF191 shows 94% identity to its mouse homologue zinc finger protein 191(Zfp191), which is the most highly conserved among the human-mouse SCAN family member orthologues pairs. ...

journal_title：BMC genomics

authors： Li J,Chen X,Gong X,Liu Y,Feng H,Qiu L,Hu Z,Zhang J

更新日期：2009-05-22 00:00:00

abstract：BACKGROUND:Incilaria (= Meghimatium) fruhstorferi is an air-breathing land slug found in restricted habitats of Japan, Taiwan and selected provinces of South Korea (Jeju, Chuncheon, Busan, and Deokjeokdo). The species is on a decline due to depletion of forest cover, predation by natural enemies, and collection. To fac...

journal_title：BMC genomics

authors： Patnaik BB,Chung JM,Hwang HJ,Sang MK,Park JE,Min HR,Cho HC,Dewangan N,Baliarsingh S,Kang SW,Park SY,Jo YH,Park HS,Kim WJ,Han YS,Lee JS,Lee YS

更新日期：2019-02-26 00:00:00

abstract：BACKGROUND:Genome-wide association studies have revealed associations between single-nucleotide polymorphisms (SNPs) and phenotypes such as disease symptoms and drug tolerance. To address the small sample size for rare variants, association studies tend to group gene or pathway level variants and evaluate the effect on...

journal_title：BMC genomics

authors： Hasegawa T,Kojima K,Kawai Y,Misawa K,Mimori T,Nagasaki M

更新日期：2016-09-21 00:00:00

abstract：BACKGROUND:Colon cancer occurrence is increasing worldwide, making it the third most frequent cancer. Although many therapeutic options are available and quite efficient at the early stages, survival is strongly decreased when the disease has spread to other organs. The identification of molecular markers of colon canc...

journal_title：BMC genomics

authors： Durand S,Trillet K,Uguen A,Saint-Pierre A,Le Jossic-Corcos C,Corcos L

更新日期：2017-09-30 00:00:00

abstract：BACKGROUND:The plastome of medicinal and endangered species in Kingdom of Saudi Arabia, Barleria prionitis was sequenced. The plastome was compared with that of seven Acanthoideae species in order to describe the plastome, spot the microsatellite, assess the dissimilarities within the sampled plastomes and to infer the...

journal_title：BMC genomics

authors： Alzahrani DA,Yaradua SS,Albokhari EJ,Abba A

更新日期：2020-06-06 00:00:00

abstract：BACKGROUND:Cytoplasmic male sterility (CMS) is an inability to produce functional pollen that is caused by mutation of the mitochondrial genome. Comparative analyses of mitochondrial genomes of lines with and without CMS in several species have revealed structural differences between genomes, including extensive rearra...

journal_title：BMC genomics

authors： Jo YD,Choi Y,Kim DH,Kim BD,Kang BC

更新日期：2014-07-04 00:00:00

abstract：BACKGROUND:Nicotiana benthamiana is a widely used model plant species for research on plant-pathogen interactions as well as other areas of plant science. It can be easily transformed or agroinfiltrated, therefore it is commonly used in studies requiring protein localization, interaction, or plant-based systems for pro...

journal_title：BMC genomics

authors： Baksa I,Nagy T,Barta E,Havelda Z,Várallyay É,Silhavy D,Burgyán J,Szittya G

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:In contrast to wild species, which have typically evolved phenotypes over long periods of natural selection, domesticates rapidly gained human-preferred agronomic traits in a relatively short-time frame via artificial selection. Under domesticated conditions, many traits can be observed that cannot only be d...

journal_title：BMC genomics

authors： Xiang H,Li X,Dai F,Xu X,Tan A,Chen L,Zhang G,Ding Y,Li Q,Lian J,Willden A,Guo Q,Xia Q,Wang J,Wang W

更新日期：2013-09-23 00:00:00