Abstract:
BACKGROUND:There is growing recognition that horizontal DNA transfer, a process known to be common in prokaryotes, is also a significant source of genomic variation in eukaryotes. Horizontal transfer of transposable elements (HTT) may be especially prevalent in eukaryotes given the inherent mobility, widespread occurrence, and prolific abundance of these elements in many eukaryotic genomes. RESULTS:Here, we provide evidence for a new case of HTT of the transposon family OposCharlie1 (OC1) in the Tasmanian devil, Sarcophilus harrisii. Bioinformatic analyses of OC1 sequences in the Tasmanian devil genome suggest that this transposon infiltrated the common ancestor of the Dasyuridae family ~17 million years ago. This estimate is corroborated by a PCR-based screen for the presence/absence of this family in Tasmanian devils and closely-related species. CONCLUSIONS:This case of HTT is the first to be reported in dasyurids. It brings the number of animal lineages independently invaded by OC1 to 12, and adds a fourth continent to the pandemic-like pattern of invasion of this transposon. In the context of these data, we discuss the evolutionary history of this transposon family and its potential impact on the diversification of marsupials.
journal_name
BMC Genomicsjournal_title
BMC genomicsauthors
Gilbert C,Waters P,Feschotte C,Schaack Sdoi
10.1186/1471-2164-14-134subject
Has Abstractpub_date
2013-02-27 00:00:00pages
134issn
1471-2164pii
1471-2164-14-134journal_volume
14pub_type
杂志文章相关文献
BMC GENOMICS文献大全abstract:BACKGROUND:Intensive research based on the inverse expression relationship has been undertaken to discover the miRNA-mRNA regulatory modules involved in the infection of Hepatitis C virus (HCV), the leading cause of chronic liver diseases. However, biological studies in other fields have found that inverse expression r...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-16-S2-S11
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Equally important and challenging as genome annotation, is the subsequent classification of predicted genes into their respective pathways. The Kyoto Encyclopedia of Genes and Genomes (KEGG) represents a database consisting of known genes and their respective biochemical functionalities. Although accessible ...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-6-60
更新日期:2005-05-03 00:00:00
abstract:BACKGROUND:Typhoid fever is an infectious disease of global importance that is caused by Salmonella enterica subsp. enterica serovar Typhi (S. Typhi). This disease causes an estimated 200,000 deaths per year and remains a serious global health threat. S. Typhi is strictly a human pathogen, and some recovered individual...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-15-1007
更新日期:2014-11-20 00:00:00
abstract:BACKGROUND:Color polymorphism in the nacre of pteriomorphian bivalves is of great interest for the pearl culture industry. The nacreous layer of the Polynesian black-lipped pearl oyster Pinctada margaritifera exhibits a large array of color variation among individuals including reflections of blue, green, yellow and pi...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-015-1776-x
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:An underlying tenet of the epigenetic code hypothesis is the existence of protein domains that can recognize various chromatin structures. To date, two major candidates have emerged: (i) the bromodomain, which can recognize certain acetylation marks and (ii) the chromodomain, which can recognize certain meth...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-7-6
更新日期:2006-01-16 00:00:00
abstract:BACKGROUND:Native cattle breeds are an important source of genetic variation because they might carry alleles that enable them to adapt to local environment and tough feeding conditions. Jiaxian Red, a Chinese native cattle breed, is reported to have originated from crossbreeding between taurine and indicine cattle; th...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-020-07340-0
更新日期:2021-01-09 00:00:00
abstract:BACKGROUND:The floral transition plays a vital role in the life of ornamental plants. Despite progress in model plants, the molecular mechanisms of flowering regulation remain unknown in perennial plants. Rosa chinensis 'Old Blush' is a unique plant that can flower continuously year-round. In this study, gene expressio...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-017-3584-y
更新日期:2017-02-23 00:00:00
abstract:BACKGROUND:The common marmoset monkey (Callithrix jacchus), a small non-endangered New World primate native to eastern Brazil, is becoming increasingly used as a non-human primate model in biomedical research, drug development and safety assessment. In contrast to the growing interest for the marmoset as an animal mode...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-8-190
更新日期:2007-06-25 00:00:00
abstract:BACKGROUND:The WRKY gene family is one of the most important families in higher plants. As transcription factors, they actively respond to biotic and abiotic stress and are also involved in plant development. Chinese jujube (Ziziphus jujuba Mill.) is the largest type of dried fruit tree in China in terms of production,...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-019-5789-8
更新日期:2019-06-07 00:00:00
abstract:BACKGROUND:Tumor genomes are often highly heterogeneous, consisting of genomes from multiple subclonal types. Complete characterization of all subclonal types is a fundamental need in tumor genome analysis. With the advancement of next-generation sequencing, computational methods have recently been developed to infer t...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-16-S2-S1
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Oxidative stress caused by ground level ozone is a contributor to yield loss in a number of important crop plants. Soybean (Glycine max) is considered to be ozone sensitive, and current research into its response to oxidative stress is limited. To better understand the genetic response in soybean to oxidativ...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-015-1637-7
更新日期:2015-06-04 00:00:00
abstract:BACKGROUND:The incidence of congenital heart disease (CHD) is continuously increasing among infants born alive nowadays, making it one of the leading causes of infant morbidity worldwide. Various studies suggest that both genetic and environmental factors lead to CHD, and therefore identifying its candidate genes and d...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-12-592
更新日期:2011-12-02 00:00:00
abstract:BACKGROUND:Pyrenophora tritici-repentis (Ptr) is a necrotrophic fungal pathogen that causes the major wheat disease, tan spot. We set out to provide essential genomics-based resources in order to better understand the pathogenicity mechanisms of this important pathogen. RESULTS:Here, we present eight new Ptr isolate g...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-018-4680-3
更新日期:2018-04-23 00:00:00
abstract:BACKGROUND:Elucidating gut microbiota among gallstone patients as well as the complex bacterial colonization of cholesterol gallstones may help in both the prediction and subsequent lowered risk of cholelithiasis. To this end, we studied the composition of bacterial communities of gut, bile, and gallstones from 29 gall...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-14-669
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:Biocontrol of bacterial pathogens by bacteriophages (phages) represents a promising strategy. Vibrio alginolyticus, a gram-negative bacterium, is a notorious pathogen responsible for the loss of economically important farmed marine animals. To date, few V. alginolyticus phages have been successfully isolated...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-018-5131-x
更新日期:2018-10-11 00:00:00
abstract:BACKGROUND:Genome-wide expression profiles are altered during biological aging and can describe molecular regulation of tissue degeneration. Age-regulated mRNA expression trends from cross-sectional studies could describe how aging progresses. We developed a novel statistical methodology to identify age-regulated expre...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-15-132
更新日期:2014-02-14 00:00:00
abstract:BACKGROUND:Acinetobacter baumannii is a significant hospital pathogen, particularly due to the dissemination of highly multidrug resistant isolates. Genome data have revealed that A. baumannii is highly genetically diverse, which correlates with major variations seen at the phenotypic level. Thus far, comparative genom...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-15-1020
更新日期:2014-11-25 00:00:00
abstract:BACKGROUND:Defensins are important components of innate immunity to combat bacterial and viral infections, and can even elicit antitumor responses. Clusters of defensin (DEF) genes are located in a 2 Mb range of the human chromosome 8p23.1. This DEF locus, however, represents one of the regions in the euchromatic part ...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-5-92
更新日期:2004-12-10 00:00:00
abstract:BACKGROUND:The formation of flowers is one of the main model systems to elucidate the molecular mechanisms that control developmental processes in plants. Although several studies have explored gene expression during flower development in the model plant Arabidopsis thaliana on a genome-wide scale, a continuous series ...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-015-1699-6
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Gene ontology analysis using the microarray database generated in a previous study by this laboratory was used to further evaluate how maternal dietary supplementation with pyridoxine combined with different sources of selenium (Se) affected global gene expression of expanded porcine blastocysts. Data were g...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-018-5237-1
更新日期:2018-11-21 00:00:00
abstract:BACKGROUND:MicroRNAs (miRNAs) post-transcriptionally regulate a variety of genes involved in eukaryotic cell growth, development, metabolism and other biological processes, and numerous miRNAs are implicated in the initiation and progression of cancer. Enzootic nasal adenocarcinoma (ENA), an epithelial tumor induced in...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-016-3238-5
更新日期:2016-11-08 00:00:00
abstract:BACKGROUND:Nontuberculous mycobacterium (NTM) species are ubiquitous microorganisms. NTM pulmonary disease (NTM-PD) is thought to be caused not by human-to-human transmission but by independent environmental acquisition. However, recent studies using next-generation sequencing (NGS) have reported trans-continental spre...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-020-6738-2
更新日期:2020-04-23 00:00:00
abstract:BACKGROUND:The Pregnancy-associated glycoproteins (PAGs) belong to a large family of aspartic peptidases expressed exclusively in the placenta of species in the Artiodactyla order. In cattle, the PAG gene family is comprised of at least 22 transcribed genes, as well as some variants. Phylogenetic analyses have shown th...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-10-185
更新日期:2009-04-24 00:00:00
abstract:BACKGROUND:MECP2, the gene mutated in the majority of Rett syndrome cases, is a transcriptional regulator that can activate or repress transcription. Although the transcription regulatory function of MECP2 has been known for over a decade, it remains unclear how transcriptional dysregulation leads to the neurodevelopme...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-016-2746-7
更新日期:2016-06-06 00:00:00
abstract:BACKGROUND:Most published genome sequences are drafts, and most are dominated by computational gene prediction. Draft genomes typically incorporate considerable sequence data that are not assigned to chromosomes, and predicted genes without quality confidence measures. The current Actinidia chinensis (kiwifruit) 'Hongy...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-018-4656-3
更新日期:2018-04-16 00:00:00
abstract:BACKGROUND:Phenomena such as incomplete lineage sorting, horizontal gene transfer, gene duplication and subsequent sub- and neo-functionalisation can result in distinct local phylogenetic relationships that are discordant with species phylogeny. In order to assess the possible biological roles for these subdivisions, t...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-14-347
更新日期:2013-05-24 00:00:00
abstract:BACKGROUND:Blood-born miRNA signatures have recently been reported for various tumor diseases. Here, we compared the miRNA signature in Wilms tumor patients prior and after preoperative chemotherapy according to SIOP protocol 2001. RESULTS:We did not find a significant difference between miRNA signature of both groups...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-13-379
更新日期:2012-08-07 00:00:00
abstract:BACKGROUND:Panax notoginseng (Burk) F.H. Chen is important medicinal plant of the Araliacease family. Triterpene saponins are the bioactive constituents in P. notoginseng. However, available genomic information regarding this plant is limited. Moreover, details of triterpene saponin biosynthesis in the Panax species ar...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-12-S5-S5
更新日期:2011-12-23 00:00:00
abstract:BACKGROUND:Gibberella ear rot (GER) is one of the most economically important fungal diseases of maize in the temperate zone due to moldy grain contaminated with health threatening mycotoxins. To develop resistant genotypes and control the disease, understanding the host-pathogen interaction is essential. RESULTS:RNA-...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-018-4513-4
更新日期:2018-02-09 00:00:00
abstract:BACKGROUND:The SOS response is a well-known regulatory network present in most bacteria and aimed at addressing DNA damage. It has also been linked extensively to stress-induced mutagenesis, virulence and the emergence and dissemination of antibiotic resistance determinants. Recently, the SOS response has been shown to...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-13-58
更新日期:2012-02-03 00:00:00