当前位置： SCI文献检索 > JOURNAL OF ASSISTED REPRODUCTION AND GENETICS期刊下所有文献 > Association between peak estradiol levels and ovarian torsion among symptomatic patients receiving gonadotropin treatment.

Association between peak estradiol levels and ovarian torsion among symptomatic patients receiving gonadotropin treatment.

Abstract：

PURPOSE:Ovarian torsion is a surgical emergency that can be clinically challenging to diagnose. Patients who have received assisted reproductive technologies (ART) are a subset of women with an increased risk for torsion. As the ART population continues to increase, there is a need to delineate risk factors for the development of ovarian torsion in this unique population. A pilot study was performed to determine the proportion of patients with suspected ovarian torsion who have received ART and to identify possible diagnostic biomarkers for ovarian torsion among these patients. METHODS:A single institution retrospective cohort study of patients taken to surgery for suspected ovarian torsion over a 5-year period. RESULTS:During the study period, 171 patients were taken to surgery for suspected ovarian torsion. Patients receiving ART constituted 19 (11%) of these patients. Among the 19 fertility treatment patients, 16 had received treatment with gonadotropins, 10 of which had surgically confirmed ovarian torsion. These ten patients had higher preoperative peak estradiol levels (3122 versus 1875 pg/mL, p = 0.05) and a larger ovarian diameter (9.7 versus 7.6 cm, p = 0.05) than the six patients receiving gonadotropins found to not have ovarian torsion. CONCLUSIONS:These results suggest infertility treatment using gonadotropins for ovarian hyperstimulation may be an independent risk factor for ovarian torsion as suggested by the disproportionate number of such individuals represented in the study population (9% of all patients, 84% of fertility patients). Additionally, among women taking gonadotropins, an association exists between peak estradiol levels, ovarian diameter, and risk for ovarian torsion.

journal_name

J Assist Reprod Genet

journal_title

Journal of assisted reproduction and genetics

authors

Romanski PA,Melamed A,Elias KM,Stanic AK,Anchan RM

doi

10.1007/s10815-017-0901-y

subject

Has Abstract

pub_date

2017-05-01 00:00:00

pages

627-631

issue

eissn

1058-0468

issn

1573-7330

pii

10.1007/s10815-017-0901-y

journal_volume

pub_type

杂志文章

在线工具

Association between peak estradiol levels and ovarian torsion among symptomatic patients receiving gonadotropin treatment.