当前位置： SCI文献检索 > Jundishapur Journal of Microbiology期刊下所有文献 > Carbapenem Susceptibility and Multidrug-Resistance in Pseudomonas aeruginosa Isolates in Egypt.

Carbapenem Susceptibility and Multidrug-Resistance in Pseudomonas aeruginosa Isolates in Egypt.

Abstract：

BACKGROUND:Resistant Pseudomonas aeruginosa is a serious concern for antimicrobial therapy, as the common isolates exhibit variable grades of resistance, involving beta-lactamase enzymes, beside native defense mechanisms. OBJECTIVES:The present study was designed to determine the occurrence of Metallo-β- Lactamases (MBL) and Amp C harboring P. aeruginosa isolates from Suez Canal university hospital in Ismailia, Egypt. METHODS:A total of 147 P. aeruginosa isolates, recovered from 311 patients during a 10-month period, were collected between May 2013 and February 2014; the isolates were collected from urine, wound and sputum. Minimum inhibitory concentration (MIC) determined by agar dilution methods was ≥2 μg/mL for meropenem and imipenem. Identification of P. aeruginosa was confirmed using API 20NE. Metallo-β- Lactamases and Amp C were detected based on different phenotypic methods. RESULTS:Overall, 26.5% of P. aeruginosa isolates (39/147) were carbapenem resistant isolates. Furthermore, 64.1% (25/39) were MBL producers, these isolates were screened by the combined disc and disc diffusion methods to determine the ability of MBL production. Both MBL and Amp C harbored P. aeruginosa isolates were 28% (7/25). Sixty-four percent of P. aeruginosa isolates were multidrug resistant (MDR) (16/25). The sensitivity toward polymyxin, imipenem, norfloxacin, piperacillin-tazobactam and gentamicin was 99%, 91%, 88%, 82% and 78%, respectively. The resistance rate towards cefotaxime, ceftazidime, cefepime, aztreonam and meropenem was 98.6%, 86%, 71.4%, 34% and 30%, respectively. CONCLUSIONS:Multidrug resistance was significantly associated with MBL production in P. aeruginosa. Early detection of MBL-producing P. aeruginosa and hospital antibiotic policy prescription helps proper antimicrobial therapy and avoidance of dissemination of these multidrug resistance isolates.

journal_name

Jundishapur J Microbiol

journal_title

Jundishapur journal of microbiology

authors

Hashem H,Hanora A,Abdalla S,Shawky A,Saad A

doi

10.5812/jjm.30257

subject

Has Abstract

pub_date

2016-10-02 00:00:00

pages

e30257

issue

11

eissn

2008-3645

issn

2008-4161

journal_volume

9

pub_type

杂志文章

相关文献

Jundishapur Journal of Microbiology文献大全
  • Bioassay Guided Fractionation of an Anti-Methicillin-Resistant Staphylococcus aureus Flavonoid From Bromus inermis Leyss Inflorescences.

    abstract：BACKGROUND:Plants are considered as promising sources of new antibacterial agents as well as bioassay guided fractionation. OBJECTIVES:In the present work, the antibacterial properties, especially against methicillin-resistant Staphylococcus aureus (MRSA), of Bromus inermis inflorescence was studied, using the bioassa...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.12739

    authors： Aliahmadi A,Mirzajani F,Ghassempour A,Sonboli A

    更新日期：2014-12-01 00:00:00

  • Genotyping of coa and aroA Genes of Methicillin-Resistant Staphylococcus aureus Strains Isolated From Nasal Samples in Western Iran.

    abstract：BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial pathogen frequently isolated in both hospital and community environments. Methicillin-resistant Staphylococcus aureus is considered a major nosocomial pathogen that causes severe morbidity and mortality. OBJECTIVES:The main objective of this ...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.26460

    authors： Mohajeri P,Azizkhani S,Farahani A,Norozi B

    更新日期：2016-01-02 00:00:00

  • Antagonistic Characteristics Against Food-borne Pathogenic Bacteria of Lactic Acid Bacteria and Bifidobacteria Isolated from Feces of Healthy Thai Infants.

    abstract：BACKGROUND:Food-borne pathogens are among the most significant problems in maintaining the health of people. Many probiotics have been widely reported to alleviate and protect against gastrointestinal infections through antibacterial secretion. However, the majority of them cannot always play antagonistic roles under g...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.8(5)2015.18264

    authors： Uraipan S,Hongpattarakere T

    更新日期：2015-06-01 00:00:00

  • Molecular Identification of Resistance Determinants, Integrons and Genetic Relatedness of Extensively Drug Resistant Acinetobacter baumannii Isolated From Hospitals in Tehran, Iran.

    abstract：BACKGROUND:Acinetobacter baumannii has emerged as an important nosocomial pathogen. Hospital outbreaks of extensively drug resistant (XDR) A. baumannii are a great concern. OBJECTIVES:Aims of this study were to characterize the resistance determinants and genetic relatedness of (XDR) A. baumannii isolates in hospitals...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.27021v2

    authors： Najar Peerayeh S,Karmostaji A

    更新日期：2015-07-25 00:00:00

  • Diagnostic Value of Serum Adenosine Deaminase (ADA) Level for Pulmonary Tuberculosis.

    abstract：BACKGROUND:Diagnosis of tuberculosis (TB) is not always easy, thus employing methods with a short duration and acceptable sensitivity and specificity is necessary to diagnose TB. OBJECTIVES:The aim of this study was to investigate the diagnostic value of serum adenosine deaminase (ADA) level for diagnosis of pulmonary...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.21760

    authors： Salmanzadeh S,Tavakkol H,Bavieh K,Alavi SM

    更新日期：2015-03-21 00:00:00

  • Molecular and Serological Evaluation of Toxoplasma gondii Infection in Reared Turkeys in Fars Province, Iran.

    abstract：BACKGROUND:Toxoplasmosis is a parasitic disease caused by the protozoan Toxoplasma gondii. This parasite infects most of warm-blooded animals, including birds. Turkeys are one of these animals which might be infected by this parasite. Little is known about the prevalence of T. gondii in turkeys in Iran. OBJECTIVES:The...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.11598

    authors： Sarkari B,Asgari Q,Bagherian N,Ashkani Esfahani S,Kalantari M,Mohammadpour I,Ashrafmansori M,Amerinia M,Sabet Sarvestani F

    更新日期：2014-07-01 00:00:00

  • Expression Profiles of TGF-β and TLR Pathways in Porphyromonas gingivalis and Prevotella intermedia Challenged Osteoblasts.

    abstract：BACKGROUND:The presence of certain oral pathogens at implant sites can hinder the osseointegration process. However, it is unclear how and by what microorganisms it happens. OBJECTIVES:This study investigated whether the presence of oral pathogens of Porphyromonas gingivalis and Prevotella intermedia individually, pla...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.8(4)2015.17920

    authors： Aydin K,Ekinci FY,Korachi M

    更新日期：2015-04-18 00:00:00

  • Seroprevalence of Hepatitis A and E Virus Infections Among Healthy Population in Shiraz, Southern Iran.

    abstract：BACKGROUND:Enterically-transmitted acute viral hepatitis is caused predominantly by hepatitis A virus (HAV) and hepatitis E virus (HEV). The prevalence of HEV and HAV infections varies in different geographical regions. OBJECTIVES:This study was conducted to determine the prevalence of HEV and HAV infections among Ira...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.19311v2

    authors： Asaei S,Ziyaeyan M,Moeini M,Jamalidoust M,Behzadi MA

    更新日期：2015-07-27 00:00:00

  • Gallbladder hydrops due to viral hepatitis a infection: a case report.

    abstract：INTRODUCTION:Acute Hepatitis A Virus (HAV) infection is common in the developing countries among children, but hydrops of gallbladder due to hepatitis A infection is an uncommon presentation. CASE PRESENTATION:A five-year-old boy was admitted in Namazi Hospital, Shiraz, Iran due to jaundice and severe abdominal pain f...

    journal_title：Jundishapur journal of microbiology

    pub_type：

    doi：10.5812/jjm.15779

    authors： Aldaghi M,Haghighat M,Dehghani SM

    更新日期：2014-12-10 00:00:00

  • Correlation of Multi-drug Resistance, Integron and blaESBL Gene Carriage With Genetic Fingerprints of Extended-Spectrum β-Lactamase Producing Klebsiella pneumoniae.

    abstract：BACKGROUND:Some genetic and phenotypic variables are associated among distinct microbial populations. OBJECTIVES:The associations between multi-drug resistance (MDR) phenotypes, prevalence of antibiotic resistance integrons (ARIs), bla SHV, bla TEM and bla CTX-M gene carriage and genetic fingerprints of random amplifi...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.8747

    authors： Ashayeri-Panah M,Feizabadi MM,Eftekhar F

    更新日期：2014-02-01 00:00:00

  • The Prevalence of Endocervical Chlamydia trachomatis Infection Among Young Females in Kashan, Iran.

    abstract：BACKGROUND:Chlamydia trachomatis is one of the major bacterial agents of the sexually transmitted diseases worldwide, especially among young females. There is no data regarding the prevalence of genital Chlamydia infection among young females in Kashan, Iran. OBJECTIVES:The current study aimed to determine the prevale...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.8(4)2015.15576

    authors： Afrasiabi S,Moniri R,Samimi M,Khorshidi A,Mousavi SG

    更新日期：2015-04-18 00:00:00

  • Effect of Propranolol Alone and in Combination with Pyrimethamine on Acute Murine Toxoplasmosis.

    abstract：BACKGROUND:Toxoplasmosis is a public health problem worldwide. This complication principally affects immunodeficient patients and pregnant women. Toxoplasma gondii is an opportunistic parasite, causing severe illness among and death of high-risk individuals and treatment is becoming increasingly difficult owing to side...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.22572

    authors： Montazeri M,Daryani A,Ebrahimzadeh M,Ahmadpour E,Sharif M,Sarvi S

    更新日期：2015-09-07 00:00:00

  • Prevalence and Mortality of Influenza A (H1N1) Virus Among Patients With Acute Respiratory Infection in Southwest Iran.

    abstract：BACKGROUND:Khuzestan and other parts of Iran were involved with Influenza A (H1N1) pandemic in 2009. OBJECTIVES:The aim of this study was to describe the prevalence and mortality of H1N1 in Behbahan, a city in Khuzestan, Southwest of Iran. PATIENTS AND METHODS:The study population consisted of cases of influenza, hos...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.9263

    authors： Alavi SM,Nashibi R,Moradpoor F

    更新日期：2014-04-01 00:00:00

  • Antibiotic Susceptibility and mecA Frequency in Staphylococcus epidermidis, Isolated From Intensive Care Unit Patients.

    abstract：BACKGROUND:Coagulase-negative staphylococci (CoNS), especially Staphylococcus epidermidis, are considered as normal flora of human epithelia and also important opportunistic pathogens for nosocomial infections. S. epidermidis can also act as a reservoir for mecA, responsible for high-level resistance to methicillin and...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.11188

    authors： Najar-Peerayeh S,Jazayeri Moghadas A,Behmanesh M

    更新日期：2014-08-01 00:00:00

  • Genetic elements associated with antimicrobial resistance among intestinal bacteria.

    abstract：BACKGROUND:Integrons are the major reasons of multidrug resistance (MDR) among enteropathogenic bacteria. Occurrence of horizontal gene transfer between integron-carrying microorganisms and other enteric bacteria may increase the rate of emergence of integron-associated antibiotic resistance. OBJECTIVES:The objective ...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.9924

    authors： Bakhshi B,Eftekhari N,Pourshafie MR

    更新日期：2014-05-01 00:00:00

  • Comparison of Serum Hepatitis B Virus DNA and HBsAg Levels Between HBeAg-Negative and HBeAg-Positive Chronic Hepatitis B Patients.

    abstract：BACKGROUND:Chronic hepatitis B consists of different clinical phases. Laboratory and histological assessments can help differentiate the clinical phases of this disease and thus lead to better management. OBJECTIVES:This study was conducted to determine laboratory and histological characteristics of HBeAg-negative and...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.21444

    authors： Keshvari M,Alavian SM,Sharafi H

    更新日期：2015-01-14 00:00:00

  • The cutaneous bacterial microflora of the bodybuilders using anabolic-androgenic steroids.

    abstract：BACKGROUND:Anabolic-androgenic steroids (AAS) abuse by the athletes has dramatically increased during the recent decades. These substances might increase the skin lipids and enhance the cutaneous microbial proliferation. OBJECTIVES:The current study aimed to investigate the potential side effects of AAS on the bacteri...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.12269

    authors： Zomorodian K,Rahimi MJ,Taheri M,Ghanbari Asad A,Khani S,Ahrari I,Pakshir K,Khashei R

    更新日期：2014-12-06 00:00:00

  • The Prevalence Rate of Helicobacter pylori Infection in, Chronic Otitis Media With Effusion Patients.

    abstract：BACKGROUND:Otitis media with effusion (OME) is a common disease in children. Viral or bacterial infections, allergy, adenoids, functional abnormalities of the Eustachian tube, and gastroesophageal reflux might have a possible role in the pathogenesis of OME. However, the exact pathogenesis of OME is still unsettled. O...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.15694

    authors： Saki N,Samarbaf Zadeh AR,Sheikhpour Jonaky R,Noori SM,Kayedani GA,Nikakhlagh S

    更新日期：2014-03-01 00:00:00

  • Comparison of Newly Assembled Full Length HIV-1 Integrase With Prototype Foamy Virus Integrase: Structure-Function Prospective.

    abstract：BACKGROUND:Drug design against human immunodeficiency virus type 1 (HIV-1) integrase through its mechanistic study is of great interest in the area in biological research. The main obstacle in this area is the absence of the full-length crystal structure for HIV-1 integrase to be used as a model. A complete structure, ...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.29773

    authors： Dayer MR

    更新日期：2016-02-15 00:00:00

  • The association between oral lichen planus and hepatitis C virus infection; a report from northeast of iran.

    abstract：BACKGROUND:The association between hepatitis C virus (HCV) infection and oral lichen planus (OLP) has been the focus of many studies. Fifteen percent of HCV infections lead to sets of extrahepatic manifestations including lichen planus (LP). The prevalence of HCV is heavily influenced by geographical location. OBJECTI...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.8(4)2015.16741

    authors： Gerayli S,Meshkat Z,Pasdar A,Mosannen Mozafari P,Banihashemi E,Khajavi MA,Rasekhi J

    更新日期：2015-04-18 00:00:00

  • Multidrug-Resistant Escherichia coli and Klebsiella pneumoniae Isolated From Patients in Kashan, Iran.

    abstract：BACKGROUND:Escherichia coli and Klebsiella pneumoniae are common human pathogens that cause a wide spectrum of infections. Antimicrobial resistance is a basic obstacle in the management of these infections which has different patterns in various regions. OBJECTIVES:In this study, the antibiotic resistance patterns and...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.27517

    authors： Moini AS,Soltani B,Taghavi Ardakani A,Moravveji A,Erami M,Haji Rezaei M,Namazi M

    更新日期：2015-10-25 00:00:00

  • Efflux Pump Inhibitor Phenylalanine-Arginine Β-Naphthylamide Effect on the Minimum Inhibitory Concentration of Imipenem in Acinetobacter baumannii Strains Isolated From Hospitalized Patients in Shahid Motahari Burn Hospital, Tehran, Iran.

    abstract：BACKGROUND:Acinetobacter baumannii has emerged as a highly troublesome pathogen and a leading cause of mortality and morbidity among hospitalized burn patients. OBJECTIVES:The aims of this study were to determine the frequency of the AdeABC genes and the role of the efflux pump (s) in the imipenem resistance of A. bau...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.19048

    authors： Gholami M,Hashemi A,Hakemi-Vala M,Goudarzi H,Hallajzadeh M

    更新日期：2015-10-12 00:00:00

  • New Insights into Sepsis Therapy Using Sepia Officinalis.

    abstract：BACKGROUND:Sepsis remains a major problem for both scientists and clinicians. Cecal ligation and puncture (CLP) is considered the gold standard for animal models of sepsis. The undesirable side effects of certain antibiotics have forced scientists to discover new, natural, and safe antimicrobial agents, such as cephalo...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.29331

    authors： Soliman AM,Fahmy SR,Sayed AA,Abd El-Latif AA

    更新日期：2016-01-02 00:00:00

  • Antibacterial Activity of Silver Nanoparticles and Their Combination with Zataria multiflora Essential Oil and Methanol Extract.

    abstract：BACKGROUND:Against a variety of antimicrobial resistant pathogens, the scientists attempted substitution of antimicrobial medicine with various nanoparticles and plant-based antibacterial substances. OBJECTIVES:The aim of this study was to assess the antibacterial effects of silver nanoparticles solely and in combinat...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.36070

    authors： Sheikholeslami S,Mousavi SE,Ahmadi Ashtiani HR,Hosseini Doust SR,Mahdi Rezayat S

    更新日期：2016-09-17 00:00:00

  • Increasing Prevalence of Aminoglycoside-Resistant Enterococcus faecalis Isolates Due to the aac(6')-aph(2") Gene: A Therapeutic Problem in Kermanshah, Iran.

    abstract：BACKGROUND:Enterococci are important pathogens in nosocomial infections. Various types of antibiotics, such as aminoglycosides, are used for treatment of these infections. Enterococci can acquire resistant traits, which can lead to therapeutic problems with aminoglycosides. OBJECTIVES:This study was designed to identi...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.28923

    authors： Khani M,Fatollahzade M,Pajavand H,Bakhtiari S,Abiri R

    更新日期：2016-03-12 00:00:00

  • Detection and Genetic Characterization of Metallo-β-Lactamase IMP-1 and VIM-2 in Pseudomonas aeruginosa Strains From Different Hospitals in Kermanshah, Iran.

    abstract：BACKGROUND:Pseudomonas aeruginosais a frequent nosocomial pathogen that causes severe diseases in many settings. Carbapenems, including meropenem and imipenem, are effective antibiotics against this organism. However, the use of carbapenems has been hampered by the emergence of strains resistant to carbapenemsvia diffe...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.22582

    authors： Abiri R,Mohammadi P,Shavani N,Rezaei M

    更新日期：2015-09-22 00:00:00

  • Isolation, Identification and Evaluation of Antimicrobial Activity of Streptomyces flavogriseus, strain ACTK2 from Soil Sample of Kodagu, Karnataka State (India).

    abstract：BACKGROUND:The search for novel antibiotics continues to be of immense importance in research programs around the world for pharmaceutical, industrial and agricultural applications. Filamentous soil bacteria, belonging to the Streptomyces genus, are widely used as an important biological tool for their ability to produ...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.15107

    authors： Khandan Dezfully N,Gottravalli Ramanayaka J

    更新日期：2015-02-10 00:00:00

  • Antibiotics use patterns for surgical prophylaxis site infection in different surgical wards of a teaching hospital in ahvaz, iran.

    abstract：BACKGROUND:Despite the effectiveness of prophylactic antimicrobials to prevent surgical site infection the use of antibiotic prophylaxis is often inappropriate. OBJECTIVES:The current study aimed to determine the pattern of prophylactic antibiotic use in a teaching hospital affiliated to Jundishapur University of Medi...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.12251

    authors： Alavi SM,Roozbeh F,Behmanesh F,Alavi L

    更新日期：2014-11-01 00:00:00

  • In Vitro Evaluation of Enzymatic and Antifungal Activities of Soil-Actinomycetes Isolates and Their Molecular Identification by PCR.

    abstract：BACKGROUND:Human cutaneous infection caused by a homogeneous group of keratinophilic fungi called dermatophytes. These fungi are the most common infectious agents in humans that are free of any population and geographic area. Microsporum canis is a cause of dermatophytosis (Tinea) in recent years in Iran and atypical s...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.8(5)2015.14874

    authors： Keikha N,Ayatollahi Mousavi SA,Nakhaei AR,Yadegari MH,Shahidi Bonjar GH,Amiri S

    更新日期：2015-05-31 00:00:00

  • The Association Between Viral Infections and Co-stimulatory Gene Polymorphisms in Kidney Transplant Outcomes.

    abstract：BACKGROUND:The surveillance of kidney transplant patients depends on function of different immunologic markers like co-stimulatory molecules. These molecules may also be associated with post kidney transplant viral related outcomes. OBJECTIVES:The aim of this study was to investigate the possible associations between ...

    journal_title：Jundishapur journal of microbiology

    pub_type： 杂志文章

    doi：10.5812/jjm.31338

    authors： Niknam A,Karimi MH,Yaghobi R,Geramizadeh B,Roozbeh J,Salehipour M,Iravani M

    更新日期：2016-02-17 00:00:00