Abstract:
BACKGROUND:Against a variety of antimicrobial resistant pathogens, the scientists attempted substitution of antimicrobial medicine with various nanoparticles and plant-based antibacterial substances. OBJECTIVES:The aim of this study was to assess the antibacterial effects of silver nanoparticles solely and in combination with Zataria multiflora essential oil and methanolic extract on some photogenic bacteria. METHODS:Minimum inhibitory concentrations (MICs) and fractional inhibitory concentrations (FICs) of plant essential oil, methanolic extract, and silver nanoparticles against bacteria were evaluated using the broth microdilution method and check board microtiter assays. RESULTS:The results of the experiment showed that the MIC and minimal bacterial concentration (MBC) values of Ag-NPs against all strains were in the range of 15.625 - 500 µg/mL, and values for the essential oil and plant extract were in the range of 1.56 - 100 mg/mL. CONCLUSIONS:Silver nanoparticles were observed to have additive effects with essential oil against Staphylococcus epidermidis and S. aureus. The obtained results suggest the need for further investigations of the antibacterial effects of the combination of silver nanoparticles with other plant extracts and essential oils.
journal_name
Jundishapur J Microbioljournal_title
Jundishapur journal of microbiologyauthors
Sheikholeslami S,Mousavi SE,Ahmadi Ashtiani HR,Hosseini Doust SR,Mahdi Rezayat Sdoi
10.5812/jjm.36070subject
Has Abstractpub_date
2016-09-17 00:00:00pages
e36070issue
10eissn
2008-3645issn
2008-4161journal_volume
9pub_type
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