Chemoradiotherapy and concurrent radiofrequency thermal therapy to treat primary rectal cancer and prediction of treatment responses.

abstract：:Subsequently to the publication of the above paper, the authors have drawn to our attention that, owing to errors made in the compilation of the images in Fig. 6, the images shown in Fig. 6A‑C in the article were selected incorrectly (essentially, the images shown in Fig. 6A and B were alterative presentations of the ...

journal_title：Oncology reports

authors： Chen YH,Zhou BY,Wu XJ,Xu JF,Zhang JA,Chen YH,Liang SS

更新日期：2020-12-16 00:00:00

abstract：:Post‑transcriptional mechanisms are an important approach in the treatment of cancer, and may also be hijacked by tumor cells to help adapt to the local microenvironment. Filamin B (FLNB), an actin‑binding protein that provides crucial scaffolds for cell motility and signaling, has also been identified as an RNA‑bindi...

journal_title：Oncology reports

authors： Ma HR,Cao L,Wang F,Cheng C,Jiang R,Zhou H,Xie Z,Wuermanbieke S,Qian Z

更新日期：2020-05-01 00:00:00

abstract：:The incidence of malignant melanoma has increased greatly in recent decades presenting a high mortality rate despite intensive efforts in this area of research. Recent studies indicate that the chemokine receptor 4 (CXCR4) plays a critical role in cancer. Thus, it has been reported that CXCL12 binding to CXCR4 initiat...

journal_title：Oncology reports

authors： André ND,Silva VA,Watanabe MA,De Lucca FL

更新日期：2016-04-01 00:00:00

abstract：:Prostate cancer (PCa) is a leading cause of death among men. The dysregulation of metabolism and autophagy contributes to the progression of PCa. The transcription factor specificity protein 1 (Sp1) is implicated in the regulation of metabolism and autophagy. We confirmed that Sp1 is overexpressed in castration-resist...

journal_title：Oncology reports

authors： Ling Z,Liu D,Zhang G,Liang Q,Xiang P,Xu Y,Han C,Tao T

更新日期：2017-09-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is different from other solid tumors because it is commonly associated with the occurrence of intrahepatic metastasis. Additionally, the liver, unlike other organs, is the main site of coagulation and fibrinolytic factor production. Therefore, it was speculated that coagulation and fibri...

journal_title：Oncology reports

authors： Li X,Gu B,Wang B,Feng Z,Ma Y,Li H,Lucas A,Chen H

更新日期：2020-12-01 00:00:00

abstract：:Signal transducer and activator of transcription 3 (STAT3) plays a key role in the transformation of normal cells to cancerous cells. Although inhibitors of STAT3 have been shown to suppress the growth of multiple cancer types in vitro and in vivo, such agents are of particular interest for the prevention of breast ca...

journal_title：Oncology reports

authors： Shoemaker RH,Fox JT,Juliana MM,Moeinpour FL,Grubbs CJ

更新日期：2019-09-01 00:00:00

abstract：:The incidence of malignant melanoma is increasing. The discovery of agents specifically targeting the mutated cascades has provided a good response for patients with oncogenic B-Raf proto-оncogene, serine/threonine kinase (BRAF). However, numerous studies continue to focus on novel methods of treatment to overcome acq...

journal_title：Oncology reports

authors： Ryabaya O,Prokofieva A,Khochenkov D,Abramov I,Zasedatelev A,Stepanova E

更新日期：2018-07-01 00:00:00

abstract：:Previous studies have shown that S100P contributes to the development of a number of tumors. However, its prognostic significance in colorectal cancer (CRC) has not been demonstrated. This study aimed to confirm the expression of S100P in colorectal cancer as well as the epigenetic mechanism underlying its gene expres...

journal_title：Oncology reports

authors： Wang Q,Zhang YN,Lin GL,Qiu HZ,Wu B,Wu HY,Zhao Y,Chen YJ,Lu CM

更新日期：2012-07-01 00:00:00

abstract：:Chronic stress and a high-fat diet are well-documented risk factors associated with the renin-angiotensin system in the development of breast cancer. The angiotensin II type 1 receptor (AT1R) is a novel component of the renin-angiotensin system. Several recent studies have focused on the function of AT1R in cell proli...

journal_title：Oncology reports

authors： Du N,Feng J,Hu LJ,Sun X,Sun HB,Zhao Y,Yang YP,Ren H

更新日期：2012-06-01 00:00:00

abstract：:The identification of the specific molecular targets, which underlie liver carcinogenesis is essential for the establishment of an effective strategy for the prevention and/or treatment of hepatocellular carcinomas (HCCs). We previously found that a malfunction of RXRalpha due to its aberrant phosphorylation was assoc...

journal_title：Oncology reports

authors： Ando N,Shimizu M,Okuno M,Matsushima-Nishiwaki R,Tsurumi H,Tanaka T,Moriwaki H

更新日期：2007-10-01 00:00:00

abstract：:The transmembrane (TM) receptor encoded by the HER-2 proto-oncogene (HER-2) is amplified in several types of human carcinomas and premalignant states and provides an important target for cancer therapy. While overexpression of HER-2 should lead to increased CTL epitope formation due to the attendant increase in higher...

journal_title：Oncology reports

authors： Castilleja A,Ward NE,Epstein RB,Kudelka AP,Gershenson DM,Efferson CL,O'Brian CA,Ioannides CG

更新日期：2002-09-01 00:00:00

abstract：:We have previously reported a high prevalence of hypothyroidism among patients with uveal melanoma. The objectives of the present study were to determine if a similar pattern of thyroid pathology exists among patients with cutaneous melanoma as well. To address this question, the medical records of all patients regist...

journal_title：Oncology reports

authors： Ellerhorst JA,Cooksley CD,Broemeling L,Johnson MM,Grimm EA

更新日期：2003-09-01 00:00:00

abstract：:Cytochalasin B (CB) is a cell-permeable mycotoxin. It inhibits cytoplasmic division by blocking the formation of contractile microfilaments, it inhibits cell movement and induces nuclear extrusion. In the present study, we investigated the anticancer activity of CB in HeLa human cervical carcinoma cells. CB showed sig...

journal_title：Oncology reports

authors： Hwang J,Yi M,Zhang X,Xu Y,Jung JH,Kim DK

更新日期：2013-10-01 00:00:00

abstract：:MicroRNAs (miRNAs) are small non-coding RNAs of 20-25 nucleotides in length that are capable of modulating gene expression post-transcriptionally. The potential roles of miRNAs in the tumorigenesis of glioblastoma (GBM) have been under intensive studies in the past few years. In the present study, we found a positive ...

journal_title：Oncology reports

authors： Jiang H,Hua D,Zhang J,Lan Q,Huang Q,Yoon JG,Han X,Li L,Foltz G,Zheng S,Lin B

更新日期：2014-05-01 00:00:00

abstract：:Perylenequinones that generate reactive oxygen species (ROS) when illuminated with visible light have been recommended as photodynamic chemotherapeutic agents. One of these is calphostin C (CalC), the action of the photo-activated derivative of which, CalCphiE, has been ascribed to its ability to selectively and irrev...

journal_title：Oncology reports

authors： Chiarini A,Whitfield JF,Pacchiana R,Marconi M,Armato U,Dal Prà I

更新日期：2010-04-01 00:00:00

abstract：:Anti-cytotoxic T lymphocyte antigen-4 (CTLA-4) treatment is effective for the treatment of primary tumors, but not sufficient for the treatment of metastatic tumors, likely owing to the effects of the tumor microenvironment. In this study, we aimed to determine the therapeutic effects of combined treatment with a matr...

journal_title：Oncology reports

authors： Li M,Xing S,Zhang H,Shang S,Li X,Ren B,Li G,Chang X,Li Y,Li W

更新日期：2016-03-01 00:00:00

abstract：:Gastric cancer (GC) is one of the most common causes of cancer‑related mortality worldwide. Despite remarkable progress in the diagnosis and treatment of GC, a large number of cases are diagnosed as advanced GC, and treatment failure occurs. Emerging evidence has shown that non‑coding RNAs (ncRNAs), especially microRN...

journal_title：Oncology reports

authors： Shao Z,Gao D,Chen L,Ding W,Yu Q

更新日期：2020-10-01 00:00:00

abstract：:The TP53 mutation (R175H) is one of the most common mutations in human cancer. It is a highly attractive strategy for cancer therapy to find the genes that lead the R175H-expressing cancer cells. The aim of this study was to identify the synthetic sick/lethal gene interacting with R175H. Using lentiviral bar-coded com...

journal_title：Oncology reports

authors： Imai H,Kato S,Sakamoto Y,Kakudo Y,Shimodaira H,Ishioka C

更新日期：2014-03-01 00:00:00

abstract：:This retrospective study was designed to evaluate the prognostic value of immunohistochemically detected nm23-expression in invasive breast cancer. Cellular expression of nm23 was assessed in 325 primary breast cancer tissues by immunohistochemistry. The data were correlated to established functional factors of progno...

journal_title：Oncology reports

authors： Göhring UJ,Eustermann I,Becker M,Neuhaus W,Rein DT,Schöndorf T

更新日期：2002-11-01 00:00:00

abstract：:We performed methylation specific PCR to explore the mechanism of inactivation of tumor suppressor genes P15, P16, P53 and VHL in 48 oral SCC. The frequencies of aberrant methylation on the promoter of the P15, the P16, the P53 and the VHL genes were 0.27 (13/48), 0.42 (20/48), 0.04 (2/48) and none, respectively. Alto...

journal_title：Oncology reports

authors： Yeh KT,Chang JG,Lin TH,Wang YF,Tien N,Chang JY,Chen JC,Shih MC

更新日期：2003-05-01 00:00:00

abstract：:hTERTC27, a 27-kDa hTERT C-terminal polypeptide has been demonstrated to cause hTERT-positive HeLa cell apoptosis and inhibits the growth of mouse melanoma. hTERTC27 has been associated with telomere dysfunction, regulation of gene-regulated apoptosis, the cell cycle and activation of natural killer (NK) cells, but it...

journal_title：Oncology reports

authors： Gong HX,He L,Li XP,Wang YD,Li Y,Huang JJ,Wang Z,Xie D,Kung HF,Peng Y

更新日期：2012-04-01 00:00:00

abstract：:The progress of the application of adenovirus in cancer gene therapy is hindered by the lack of expression of native adenovirus receptor on a variety of cancer types. Hence, strategies are needed to retarget the adenoviral vector to non-native cellular surface receptors. In the present study, a new peptide SWDIAWPPLKV...

journal_title：Oncology reports

authors： Wang D,Li W,Zhang H,Mao Q,Xia H

更新日期：2014-05-01 00:00:00

abstract：:Pancreatic cancer (PC) is one of the leading causes of cancer-related deaths worldwide. Frequent metastasis and recurrence are the main reasons for the poor prognosis of PC patients. Thus, the discovery of new biomarkers and wider insights into the mechanisms involved in pancreatic tumorigenesis and metastasis is cruc...

journal_title：Oncology reports

authors： Ma D,Jing X,Shen B,Liu X,Cheng X,Wang B,Fu Z,Peng C,Qiu W

更新日期：2016-08-01 00:00:00

abstract：:To elucidate the mechanism of resistance to 5-fluorouracil (5-FU) in human gastric cancer cells, we established a cell line MKN45/F2R, which acquired 5-FU resistance as a result of continuous exposure to increasing dosages of 5-FU over a year. The cell line showed 157-fold elevated 5-FU resistance compared to the MKN4...

journal_title：Oncology reports

authors： Tsutani Y,Yoshida K,Sanada Y,Wada Y,Konishi K,Fukushima M,Okada M

更新日期：2008-12-01 00:00:00

abstract：:Kruppel-like factor 9 (KLF9), a transcription factor, is critical for the inhibition of growth and development of tumors, whereas its effects in pancreatic cancer remains unclear. The purpose of the present study was to investigate the expression and functional significance of KLF9 in vitro, by assessing the expressio...

journal_title：Oncology reports

authors： Zhong Z,Zhou F,Wang D,Wu M,Zhou W,Zou Y,Li J,Wu L,Yin X

更新日期：2018-12-01 00:00:00

abstract：:Members of the Eph family of receptor tyrosine kinase have been implicated in cell-cell communication and tissue integrity during embryogenesis. We have previously demonstrated cell type specific and hormone dependent EphB4 expression in the mouse mammary parenchyma suggesting involvement in the homeostasis of this or...

journal_title：Oncology reports

authors： Berclaz G,Flütsch B,Altermatt HJ,Rohrbach V,Djonov V,Ziemiecki A,Dreher E,Andres AC

更新日期：2002-09-01 00:00:00

abstract：:In the present study, the preliminary results of the first stereotactic body radiosurgery (SRS) experience with volumetric intensity modulated arc therapy (VMAT) in oligometastatic breast and recurrent gynecological tumors (OBRGT) are reported in terms of feasibility, toxicity and efficacy. Patients were treated in a ...

journal_title：Oncology reports

authors： Macchia G,Deodato F,Cilla S,Torre G,Corrado G,Legge F,Gambacorta MA,Tagliaferri L,Mignogna S,Scambia G,Valentini V,Morganti AG,Ferrandina G

更新日期：2014-11-01 00:00:00

abstract：:The mechanisms responsible for human inflammatory bowel disease remain poorly understood. The pathogenic factors for dextran sulfate sodium (DSS)-induced colitis, one of the experimental animal colitis models, also remain unknown. Furthermore, detailed studies on DSS metabolism in the gut lumen have not been reported....

journal_title：Oncology reports

authors： Araki Y,Bamba T,Mukaisho K,Kanauchi O,Ban H,Bamba S,Andoh A,Fujiyama Y,Hattori T,Sugihara H

更新日期：2012-11-01 00:00:00

abstract：:No information is currently available regarding pancreatic cancer (PC) pattern of care in Italy. In the present study, a nationwide survey using a questionnaire was performed to enquire the local standards for PC diagnosis and radiotherapy treatment. Fifty-seven percent of 140 Italian centres completed questionnaire. ...

journal_title：Oncology reports

authors： Macchia G,Sainato A,Talamini R,Boz G,Bacigalupo A,Caravatta L,Fiore M,Friso ML,Fusco V,Lupattelli M,Mantello G,Mattiucci GC,Slim N,Sciacero P,Turri L,Valentini V,Morganti AG,Genovesi D

更新日期：2015-07-01 00:00:00

abstract：:Ras-association domain family of proteins (RASSF) is characterized by the Ras-association (RA) domain at the C-terminal. Frequent inactivation of RASSF1A gene in human cancers suggests that other members of the family may also play an important role in tumorigenesis. By in silico gene searches, the number of RASSF fam...

journal_title：Oncology reports

authors： Chow LS,Lo KW,Kwong J,Wong AY,Huang DP

更新日期：2004-10-01 00:00:00