Abstract：
:The various stages of tumor growth are characterized by typical epithelial, vascular, and secondary connective tissue changes. Narrow Band Imaging (NBI) endoscopy is a minimally invasive imaging technique that presents vascular structures in particular at a higher contrast than white light endoscopy alone. In combination with high-resolution image recording and reproduction (high-definition television, HDTV; ultra-high definition, 4K), progress has been made in otolaryngological differential diagnostics, both pre- and intraoperatively. This progress represents an important step toward a so-called optical biopsy. Flexible endoscopy in combination with NBI allows for a detailed assessment of areas of the upper aerodigestive tract that are difficult to assess by rigid endoscopy. Papillomas along with precancerous and cancerous lesions are characterized by epithelial and connective tissue changes as well as by typical perpendicular vascular changes. Systematic use of NBI is recommended in the differential diagnosis of malignant lesions of the upper aerodigestive tract. NBI also offers a significant improvement in the pre- and intraoperative assessment of superficial resection margins. In particular, the combination of NBI and contact endoscopy (compact endoscopy) facilitates excellent therapeutic decisions during tumor surgery. Intraoperative determination of resection margins at an unprecedented precision is possible. In addition, assessment of the form and extent of the perpendicular vessel loops stimulated by epithelial signaling enables differential diagnostic decisions to be made, approximating our goal of an optical biopsy.
journal_name
HNOjournal_title
HNOauthors
Arens C,Betz C,Kraft M,Voigt-Zimmermann Sdoi
10.1007/s00106-016-0284-xsubject
Has Abstractpub_date
2017-01-01 00:00:00pages
5-12issue
Suppl 1eissn
0017-6192issn
1433-0458pii
10.1007/s00106-016-0284-xjournal_volume
65pub_type
杂志文章,评审相关文献
HNO文献大全abstract：:Based on four observations of our own and a survey of the 151 cases described to date, the clinical and morphologic results of granular cell tumours of the larynx are presented. These tumours, which were considered as being of myogenic origin ("myoblastic myoma", immature rhabdomyoma", "granular cell myoblastoma" etc....
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1982-09-01 00:00:00
abstract：:Fifteen cadavers were examined bilaterally for the topography of the superior thyroid artery and vein an lower cervical ansa as an axial bundle of vessels and nerves for the infrahyoid myofascial flap. Using injections of methylene blue, the vascular territories of the superior thyroid artery were demonstrated. The su...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
abstract：BACKGROUND:The microvascular anastomosed transverse rectus abdominis muscle (TRAM) island flap has been successfully used in plastic surgery for more than 10 years. In reconstructive head and neck surgery, however, it is not yet established. METHOD:We analysed the preparation and anatomical variation in TRAM flaps in ...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s00106-005-1286-2
更新日期：2006-01-01 00:00:00
abstract：:The osteoplastic frontal sinus operation permits the complete removal of sinus mucosa and, with blockage of the frontonasal duct, the reliable obliteration of the sinus cavity. Two patients, who had had several surgical procedures for recurrent frontal sinusitis, became symptom free after this procedure. After an inte...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1978-08-01 00:00:00
abstract：:We present a retrospective study on 22 operations of exostosis of the external auditory canal in 20 patients. 8 patients were passionated by water sports. The most frequent indication for surgery (13 operations) was recurrent external otitis or ceruminal obstruction. In 7 cases the need for a wider access to the middl...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s001060050019
更新日期：2000-02-01 00:00:00
abstract：:Supplemental to the previous publication on the results of surgery and/or radiotherapy, the application of various cytostatic drugs--neoadjuvant, sequential, simultaneous, alternating or adjuvant--in addition to surgery and/or radiotherapy in the treatment of hypopharynx carcinomas is subjected to critical analysis. E...
journal_title：HNO
pub_type： 杂志文章,评审
doi：
更新日期：1994-02-01 00:00:00
abstract：BACKGROUND:As unanimously found in several consensus papers, other conditions such as learning disorders need to be ruled out prior to labelling a child as having an auditory processing disorder (APD). METHODS:In a retrospective study data from 386 children (245 boys, 141 girls) aged 6;0-9;11 years were investigated. ...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s00106-010-2193-8
更新日期：2010-12-01 00:00:00
abstract：:The author's method of suggestion therapy can lead to a total remission of sudden deafness or to a favourable precondition for later infusion therapy (Onkovertin with Sorbit + Trental). Several examples are quoted to show that an improvement of hearing of 20 DB can be attained within 30 min over different frequencies....
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1983-04-01 00:00:00
abstract：:The aim of this multicenter clinical field study was to assess the benefits of the new Freedom 24 sound processor for cochlear implant (CI) users implanted with the Nucleus 24 cochlear implant system. The study included 48 postlingually profoundly deaf experienced CI users who demonstrated speech comprehension perform...
journal_title：HNO
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1007/s00106-008-1781-3
更新日期：2009-06-01 00:00:00
abstract：:Acoustic or electrical stimulation activate specific populations of neurons in specific regions of the central auditory system to prepare for a molecular, structural, and functional remodeling within hours. Among the indicators for the initiation of neuronal remodeling is the expression of immediate early genes (IEGs)...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s00106-010-2250-3
更新日期：2011-03-01 00:00:00
abstract：:Inhibitors of angiotensin converting enzyme (ACE) are suspected of inducing angioedemas in up to 0.2% of all patients. These angioedemas are mainly localized in the upper airways and therefore can cause severe airway obstruction and even death due to suffocation. We report the case of a 64-year-old man, who underwent ...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:Only about 8% of head and neck tumors affect the midface. This anatomical area is characterized by an enormous number of functionally important structures, and it is frequently only possible to achieve small resection margin distances. To avoid complications and unfavorable results, a dedicated preparation of both pat...
journal_title：HNO
pub_type： 杂志文章,评审
doi：10.1007/s00106-018-0512-7
更新日期：2018-06-01 00:00:00
abstract：PROBLEM:Although robust algorithms for registration and segmentation are available, the majority of surgical approaches to the temporal bone are nowadays made without navigation assistance. Beside instrument navigation (IN), functions such as distance control (DC) and navigated control (NC) can be used. This study anal...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s00106-012-2558-2
更新日期：2012-12-01 00:00:00
abstract：:A case report is presented of a 54-year-old woman with tinnitus synchronous with her pulse and an ipsilateral conductive hearing loss. Otoscopy showed a pulsatile structure behind the right eardrum. Imaging with high-resolution computed tomography of the temporal bone showed an enlarged jugular vein bulb. Magnetic res...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s001060050340
更新日期：1998-11-01 00:00:00
abstract：:Failed intubation in three patients is reported. All three patients suffered sudden, extreme impaired of mask-ventilation. Twice a coniotomy with subsequent tracheostomy proved to be life saving and without permanent injury. In the other patient tracheostomy had been attempted without success, and subsequent, successf...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1987-10-01 00:00:00
abstract：:Calcium phosphate ceramics have been proposed for obliteration of the mastoid cavity in middle ear surgery. To our knowledge no experimental data are available concerning the use of homologous fibrin glue associated with hydroxyapatite (HA) in animals. Obliteration of the epitympanic space and closure of defects in th...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：BACKGROUND:In pre-school children suffering from pure non-inflammatory hyperplasia of the tonsils, tonsillotomy has recently been recommended in preference to tonsillectomy. Absence of inflammatory tonsillitis in the previous medical history is accepted as evidence that tonsillotomy is indicated. In this study, we ther...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s00106-007-1544-6
更新日期：2007-12-01 00:00:00
abstract：:Despite various methods of investigation, there are few reports as to the normal values of nasal airway resistance. A total of 56 adult subjects free of any nasal disease underwent nasal airway resistance measurement using active anterior rhinomanometry according to the guidelines of the international committee on sta...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1988-10-01 00:00:00
abstract：:Head and neck squamous cell carcinoma (HNSCC) is characterized by its intense immune suppression and its elaborate immune escape mechanisms. Due to the fact that survival rates remain low, the role of immunotherapy has become more important and the focus of current clinical studies has shifted toward antibody-based im...
journal_title：HNO
pub_type： 杂志文章,评审
doi：10.1007/s00106-016-0131-0
更新日期：2016-07-01 00:00:00
abstract：BACKGROUND:For the functional outcome after cochlear implant surgery, the electrode position is of essential importance. Therefore, radiological techniques to localize the electrode within the cochlea are becoming increasingly important. In our study, we used multi-slice computed tomography (CT) to find radiological cr...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s00106-008-1810-2
更新日期：2009-06-01 00:00:00
abstract：BACKGROUND:We examined whether training conceptualized as a complement to standard medical treatment (ST) for acute tinnitus to promote patients' capacity to distract attention from their tinnitus and to relax (distraction and relaxation training) has a positive effect on tinnitus-specific distress (tinnitus loudness, ...
journal_title：HNO
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00106-009-2019-8
更新日期：2010-05-01 00:00:00
abstract：BACKGROUND:The shortage of qualified doctors and nurses has led to a competition between hospitals. Analyzing the circumstances of the competition, nurses and doctors of so-called generation Y are important. These employees are mainly female and have different requirements compared to previous generations. Therefore, k...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s00106-012-2572-4
更新日期：2012-11-01 00:00:00
abstract：:Extensive tracheal defects after prolonged assisted ventilation, trauma or large resections in tumor surgery are a challenge in plastic and reconstructive surgery. Defects which cannot be satisfactorily repaired reguine near of an alloplastic tracheal replacement. Previous experimental and clinical experiences in the ...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1995-02-01 00:00:00
abstract：:We reviewed 192 patients who had been treated for chronic otitis media. All operations were carried out at the Department of Otolaryngology, University of Tübingen. No patient had a previous ear operation and revision operations were excluded. The observation period varied from a minimum of 1 year to a maximum of 4 1/...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s001060050184
更新日期：1997-12-01 00:00:00
abstract：:The surgical treatment of lesions of the interorbital area belongs to the field of the rhinologist. Treatment options have been extended in recent years by technical advances. These include the extension of microsurgery to the base of the skull and the use of fibrin tissue glue. We have also had experience of an osteo...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1983-09-01 00:00:00
abstract：BACKGROUND:Digitalization is significantly changing the entire healthcare sector. Hospitals must act now in order to remain competitive. OBJECTIVE:To assess which approaches exist for digitalization along the treatment chain and how digitalization can be strategically implemented. MATERIALS AND METHODS:An analysis of...
journal_title：HNO
pub_type： 杂志文章,评审
doi：10.1007/s00106-019-0655-1
更新日期：2019-05-01 00:00:00
abstract：:A retrospective study of 199 surgically treated skin carcinomas showed that the majority of the insufficiently resected tumors had a maximum diameter of 10 mm. A surgical concept is presented which allows reliable histological control of the tumor margins and an exact resection of any residual carcinoma. This therapeu...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1992-09-01 00:00:00
abstract：:The effect of different vasodilating drugs on the perilymphatic oxygen content in the cat has been examined by means of the polarographic method. The drugs used such as Papaverin, Rheomacrodex, Ronicol, Praxilen and Lasix have had no significant effect on the oxygen concentration in the perilymph. Histamin, 7% Na2CO3 ...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1978-03-01 00:00:00
abstract：BACKGROUND:The role of transoral robotic surgery (TORS) in the treatment of head and neck tumors has expanded in the last decade. OBJECTIVES:We present the development and current advances in TORS along with the current indications and contraindications, and describe future developments. METHODS:We present our own st...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s00106-015-0073-y
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND:Epistaxis is a common symptom in the medical practice. It is associated with various comorbidities and the use of medications, especially anticoagulants. Despite the high lifetime prevalence, there is limited data on prevalence and possible risk factors. METHODS:The study examines epistaxis care in a large ...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s00106-020-00940-y
更新日期：2020-09-14 00:00:00
