Comparing and evaluating the efficacy of methotrexate and actinomycin D as first-line single chemotherapy agents in low risk gestational trophoblastic disease.

abstract：OBJECTIVE:DNA methylation has been shown to be a potential biomarker for early cancer detection. The aim of this study was to evaluate DNA methylation profiles according to liquid-based Pap (LBP) test results and to assess their diagnostic value in a Korean population. METHODS:A total of 205 patients with various Papa...

journal_title：Journal of gynecologic oncology

authors： Kim MK,Lee IH,Lee KH,Lee YK,So KA,Hong SR,Hwang CS,Kee MK,Rhee JE,Kang C,Hur SY,Park JS,Kim TJ

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:Uterine leiomyomas are the most common tumor of the uterus. But the molecular causes of uterine leiomyoma remain unclear. We conducted the current investigation in order to elucidate the molecular mechanisms in the development of uterine leiomyoma. METHODS:We employed a new and accurate reverse transcription...

journal_title：Journal of gynecologic oncology

authors： Lee SO,Lee SY,Lee SR,Ju W,Kim SC

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:To evaluate survival impact of low anterior resection (LAR) in patients with epithelial ovarian cancer (EOC) grossly confined to the pelvis. METHODS:We retrospectively reviewed 397 patients who underwent primary staging surgery for treatment of 2014 International Federation of Gynecology and Obstetrics (FIGO...

journal_title：Journal of gynecologic oncology

authors： Kim M,Suh DH,Park JY,Paik ES,Lee S,Eoh KJ,Nam JH,Lee YY,Kim JW,Kim S

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between the precursors of high grade serous ovarian cancer (HGSOC) and the characteristics of patients with a low HGSOC risk in terms of the effects of pregnancy. METHODS:We prospectively examined consecutive cases in which the bilateral fallopian tubes were removed during ben...

journal_title：Journal of gynecologic oncology

authors： Ida T,Fujiwara H,Kiriu T,Taniguchi Y,Kohyama A

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:The goal of this study was to investigate the relationship between plasma levels of insulin-like growth factors-1 (IGF-1) and IGF-binding protein-3 (IGFBP-3) and the risk for cervical intraepithelial neoplasia (CIN) and cervical cancer. METHODS:Plasma levels of IGF-1 and IGFBP-3 of 44 cervical cancer patient...

journal_title：Journal of gynecologic oncology

authors： Lee SW,Lee SY,Lee SR,Ju W,Kim SC

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To validate the efficacy of Seeplex HPV4A ACE for the detection of high-risk (HR) human papillomavirus (HPV) and HPV 16 and/or HPV 18 genotypes as compared to the PCR method and the Cervista HPV assays in cervical swab samples. METHODS:Besides liquid-based cytology, additional 97 cervical swab samples were c...

journal_title：Journal of gynecologic oncology

authors： Min KJ,So KA,Lee J,Hong HR,Hong JH,Lee JK,Kim AR

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:Neoadjuvant chemotherapy (NACT) for the treatment of epithelial ovarian cancer (EOC) has remained controversial. This meta-analysis was performed to systematically assess the efficacy and safety of NACT versus primary debulking surgery (PDS) in patients with EOC. METHODS:PubMed, Embase, ClinicalTrials.gov, a...

journal_title：Journal of gynecologic oncology

authors： Lv X,Cui S,Zhang X,Ren C

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to investigate the prognostic value of lymph node ratio (LNR) in patients with stage III ovarian high-grade serous carcinoma (HGSC). METHODS:A multicenter, retrospective department database review was performed to identify patients with ovarian HGSC at 6 gynecologic oncology cen...

journal_title：Journal of gynecologic oncology

authors： Ayhan A,Ozkan NT,Sarı ME,Celik H,Dede M,Akbayır Ö,Güngördük K,Şahin H,Haberal A,Güngör T,Arvas M,Meydanlı MM

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Lower extremity lymphedema adversely affects quality of life by causing discomfort, impaired mobility and increased risk of infection. The goal of this study is to investigate factors that influence the likelihood of lymphedema in patients with endometrial cancer who undergo adjuvant radiation with or without...

journal_title：Journal of gynecologic oncology

authors： Mitra D,Catalano PJ,Cimbak N,Damato AL,Muto MG,Viswanathan AN

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the ability of four risk of malignancy indices (RMI) to detect malignant ovarian tumors. METHODS:This is a prospective study of 100 women admitted to the Department of Obstetrics and Gynecology of Gulhane Military Medicine Academy for surgical exploration of pelvic masse...

journal_title：Journal of gynecologic oncology

authors： Aktürk E,Karaca RE,Alanbay I,Dede M,Karaşahin E,Yenen MC,Başer I

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of the pulmonary recruitment maneuver (PRM) at the end of the operation to decrease laparoscopy-induced abdominal or shoulder pain after gynecological oncologic surgery. METHODS:In total, 113 women undergoing laparoscopic surgery for malignant or premalignant gynecological lesio...

journal_title：Journal of gynecologic oncology

authors： Güngördük K,Aşıcıoğlu O,Özdemir İA

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:To show noninferiority of a limited-excision (resection of the dysplastic lesion only) vs. classical Large Loop Excision of the Transformation Zone (LLETZ). METHODS:In this prospective, randomized, multicenter trial, women with human papillomavirus (HPV) positive cervical intraepithelial neoplasia grade 3 we...

journal_title：Journal of gynecologic oncology

authors： Kolben TM,Etzel LT,Bergauer F,Hagemann I,Hillemanns P,Repper M,Kaufmann AM,Sotlar K,Kolben T,Helms HJ,Gallwas J,Mahner S,Dannecker C

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the prevalence and features of non-endometrial cancers in Thai endometrial cancer (EC) patients. METHODS:EC patients treated in our institution were identified and the following data were collected: age, EC stage, histopathology, adjuvant therapy, other cancers, living status, and cause of death....

journal_title：Journal of gynecologic oncology

authors： Tangjitgamol S,Khunnarong J,Srijaipracharoen S

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:To investigate the efficacy of levonorgestrel-releasing intra-uterine system (LNG-IUS) treatment in patients affected by atypical complex hyperplasia/endometrial cancer (ACH/EC) wishing to preserve their fertility and to present fertility outcomes of those patients who actively tried to conceive. METHODS:Dat...

journal_title：Journal of gynecologic oncology

authors： Leone Roberti Maggiore U,Martinelli F,Dondi G,Bogani G,Chiappa V,Evangelista MT,Liberale V,Ditto A,Ferrero S,Raspagliesi F

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVES:To assess the clinical and cost-effectiveness of human papillomavirus (HPV) primary screening triage with p16/Ki-67 dual stain cytology compared to cytology. METHODS:We conducted an Excel®-based budget impact model to estimate the preinvasive and invasive cervical cancer cases identified, mortality rate, di...

journal_title：Journal of gynecologic oncology

authors： Termrungruanglert W,Khemapech N,Tantitamit T,Havanond P

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:In cervical intraepithelial neoplasia (CIN), p16(INK4a) immunohistochemistry has been reported to be a useful diagnostic biomarker. However, limited information is available about the association between the p16(INK4a) immunohistochemistry and the outcomes of CIN. Here, we report p16(INK4a) immunohistochemist...

journal_title：Journal of gynecologic oncology

authors： Nishio S,Fujii T,Nishio H,Kameyama K,Saito M,Iwata T,Kubushiro K,Aoki D

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:To compare plasma protein expression between patients with squamous cell carcinoma (SCC) of the cervix and normal controls. METHODS:Plasma samples from patients with benign gynecological disease (normal cervix, n=6) and cervical cancer (SCC, n=6) were subjected to plasma proteomic analysis using two dimensio...

journal_title：Journal of gynecologic oncology

authors： Jeong DH,Kim HK,Prince AE,Lee DS,Kim YN,Han J,Kim KT

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the feasibility and the safety of robotic single-site radical hysterectomy (RSSRH) plus pelvic lymphadenectomy (PL) in endometrial or cervical cancer. METHODS:Patients with endometrial cancer (EC) International Federation of Gynecology and Obstetrics (FIGO) stage II, early cervical cancer (ECC) F...

journal_title：Journal of gynecologic oncology

authors： Vizza E,Chiofalo B,Cutillo G,Mancini E,Baiocco E,Zampa A,Bufalo A,Corrado G

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVES:Two randomized, controlled studies comparing outcomes in patients treated with direct oral anticoagulants or low-molecular weight heparin for cancer-associated venous thromboembolism (VTE) have previously been performed. However, gynecologic cancers accounted for approximately 10% of the study populations. W...

journal_title：Journal of gynecologic oncology

authors： Lee JH,Lee JH,Jo KW,Huh JW,Oh YM,Lee JS

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to develop and validate a questionnaire used to assess the level of general knowledge about cervical cancer, its primary and secondary prevention, and to identify sources of information about the disease among schoolgirls and female students. METHODS:THE QUESTIONNAIRE DEVELOPMENT PR...

journal_title：Journal of gynecologic oncology

authors： Jaglarz K,Tomaszewski KA,Kamzol W,Puskulluoglu M,Krzemieniecki K

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:Synchronous occurrence of endometrial and ovarian tumors is uncommon, and they affect less than 10% of women with endometrial or ovarian cancers. The aim of this study is to describe the epidemiological and clinical factors; and survival outcomes of women with these cancers. METHODS:This is a retrospective c...

journal_title：Journal of gynecologic oncology

authors： Lim YK,Padma R,Foo L,Chia YN,Yam P,Chia J,Khoo-Tan H,Yap SP,Yeo R

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:Our previous study showed that insulin resistance (IR) was related to endometrial hyperplasia as well as endometrial cancer. But the exact impact of IR on fertility-sparing treatment in endometrial hyperplasic disease is unclear. This study investigated how IR affects fertility-sparing treatment in endometria...

journal_title：Journal of gynecologic oncology

authors： Yang B,Xie L,Zhang H,Zhu Q,Du Y,Luo X,Chen X

更新日期：2018-05-01 00:00:00

abstract：:The Gynecologic Oncology Group (GOG) has conducted multiple trials related to malignancies of the uterine corpus. Recently, several of these trials have been presented and/or published. Areas of focus included the feasibility of laparoscopic staging for endometrial cancer, the adjuvant management of locally advanced e...

journal_title：Journal of gynecologic oncology

authors： Miller DS,King LP

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:To examine the correlation between cervical cytology and final histological results in patients who have undergone loop electrosurgical excision procedure (LEEP) with or without colposcopy-directed biopsy. METHODS:A retrospective review was performed of 829 patients who underwent LEEP for abnormal cervical c...

journal_title：Journal of gynecologic oncology

authors： Cho H,Kim JH

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:To determine the predictive accuracy of the combined panels of serum human tissue kallikreins (hKs) and CA-125 for the detection of epithelial ovarian cancer. METHODS:Serum specimens collected from 5 Indonesian centers and 1 Vietnamese center were analyzed for CA-125, hK6, and hK10 levels. A total of 375 spe...

journal_title：Journal of gynecologic oncology

authors： Koh SC,Huak CY,Lutan D,Marpuang J,Ketut S,Budiana NG,Saleh AZ,Aziz MF,Winarto H,Pradjatmo H,Hoan NK,Thanh PV,Choolani M

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare operative feasibility and surgical outcome of the modified Cherney incision and vertical midline incision in patients undergoing radical hysterectomy and pelvic lymphadenectomy. METHODS:Between March 2005 and December 2007, retrospective data of 78 patients (n=17; modifie...

journal_title：Journal of gynecologic oncology

authors： Lee SH,Yim GW,Lee DW,Kim SW,Kim S,Kim JW,Kim YT

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:As cancer stem cells (CSCs) are considered as the origin of tumor development, recurrence, and drug resistance, we aimed to explore the mechanism related to modulating stemness in CSCs, thus facilitating to search for new therapeutic strategy for ovarian cancer. METHODS:In this study, ovarian cancer stem cel...

journal_title：Journal of gynecologic oncology

authors： Yue Y,Xia L,Xu S,Wang C,Wang X,Lu W,Xie X

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:To investigate the association between reproductive factors and the risk of ovarian cancer among southern Chinese women. METHODS:A hospital-based case-control study was undertaken in Guangzhou, Guangdong Province, between 2006 and 2008. A structured questionnaire was used to obtain information on parity, ora...

journal_title：Journal of gynecologic oncology

authors： Pasalich M,Su D,Binns CW,Lee AH

更新日期：2013-04-01 00:00:00

abstract：:Anastomotic leakage is a very significant complication after posterior pelvic exenteration and a major cause of postoperative morbidity and mortality. We present a patient who underwent an optimal debulking surgery for an advanced stage ovarian cancer (FIGO IIIC). On postoperative day 12, transvaginal ultrasound revea...

journal_title：Journal of gynecologic oncology

authors： Einenkel J,Holler B,Hoffmeister A

更新日期：2011-06-30 00:00:00

abstract：:Ovarian metastases from a primary urinary tract carcinoma are extremely rare. This can be difficult to distinguish from transitional cell carcinomas (TCC) of ovarian origin because of histologic similarity. A 65-year-old woman who was diagnosed with renal pelvis TCC 4 months prior was referred for evaluation of a left...

journal_title：Journal of gynecologic oncology

authors： Lee M,Jung YW,Kim SW,Kim SH,Kim YT

更新日期：2010-03-01 00:00:00