Abstract:
:We show a coding method of suspension array based on the laser induced breakdown spectroscopy (LIBS), which promotes the barcodes from analog to digital. As the foundation of digital optical barcodes, nanocrystals encoded microspheres are prepared with self-assembly encapsulation method. We confirm that digital multiplexing of LIBS-based coding method becomes feasible since the microsphere can be coded with direct read-out data of wavelengths, and the method can avoid fluorescence signal crosstalk between barcodes and analyte tags, which lead to overall advantages in accuracy and stability to current fluorescent multicolor coding method. This demonstration increases the capability of multiplexed detection and accurate filtrating, expanding more extensive applications of suspension array in life science.
journal_name
Sci Repjournal_title
Scientific reportsauthors
He Q,Liu Y,He Y,Zhu L,Zhang Y,Shen Zdoi
10.1038/srep36511subject
Has Abstractpub_date
2016-11-03 00:00:00pages
36511issn
2045-2322pii
srep36511journal_volume
6pub_type
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