Digital barcodes of suspension array using laser induced breakdown spectroscopy.

Abstract:

:We show a coding method of suspension array based on the laser induced breakdown spectroscopy (LIBS), which promotes the barcodes from analog to digital. As the foundation of digital optical barcodes, nanocrystals encoded microspheres are prepared with self-assembly encapsulation method. We confirm that digital multiplexing of LIBS-based coding method becomes feasible since the microsphere can be coded with direct read-out data of wavelengths, and the method can avoid fluorescence signal crosstalk between barcodes and analyte tags, which lead to overall advantages in accuracy and stability to current fluorescent multicolor coding method. This demonstration increases the capability of multiplexed detection and accurate filtrating, expanding more extensive applications of suspension array in life science.

journal_name

Sci Rep

journal_title

Scientific reports

authors

He Q,Liu Y,He Y,Zhu L,Zhang Y,Shen Z

doi

10.1038/srep36511

subject

Has Abstract

pub_date

2016-11-03 00:00:00

pages

36511

issn

2045-2322

pii

srep36511

journal_volume

6

pub_type

杂志文章
  • Corticotropin releasing factor excites neurons of posterior hypothalamic nucleus to produce tachycardia in rats.

    abstract::Corticotropin releasing factor (CRF), a peptide hormone involved in the stress response, holds a key position in cardiovascular regulation. Here, we report that the central effect of CRF on cardiovascular activities is mediated by the posterior hypothalamic nucleus (PH), an important structure responsible for stress-i...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep20206

    authors: Gao HR,Zhuang QX,Li B,Li HZ,Chen ZP,Wang JJ,Zhu JN

    更新日期:2016-02-01 00:00:00

  • Ultrathin Air-Stable n-Type Organic Phototransistor Array for Conformal Optoelectronics.

    abstract::Development of conformal n-channel organic phototransistor (OPT) array is urgent for future applications of organic complementary circuits in portable and wearable electronics and optoelectronics. In this work, the ultrathin conformal OPT array based on air-stable n-type PTCDI-C13H27 was fabricated. The OPT array show...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-35062-7

    authors: Liu M,Wang H,Tang Q,Zhao X,Tong Y,Liu Y

    更新日期:2018-11-09 00:00:00

  • Morphology evolution and pure red upconversion mechanism of β-NaLuF4 crystals.

    abstract::A series of β-NaLuF4 crystals were synthesized via a hydrothermal method. Hexagonal phase microdisks, microprisms, and microtubes were achieved by simply changing the amount of citric acid in the initial reaction solution. Pure red upconversion (UC) luminescence can be observed in β-NaLuF4:Yb(3+), Tm(3+), Er(3+) and L...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep28051

    authors: Lin H,Xu D,Li A,Teng D,Yang S,Zhang Y

    更新日期:2016-06-16 00:00:00

  • Fractal nature of groundwater level fluctuations affected by riparian zone vegetation water use and river stage variations.

    abstract::Groundwater systems affected by various factors can exhibit complex fractal behaviors, whose reliable characterization however is not straightforward. This study explores the fractal scaling behavior of the groundwater systems affected by plant water use and river stage fluctuations in the riparian zone, using multifr...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-51657-0

    authors: Sun H,Gu X,Zhu J,Yu Z,Zhang Y

    更新日期:2019-10-28 00:00:00

  • Comparing blood pressure measurements between a photoplethysmography-based and a standard cuff-based manometry device.

    abstract::Repeated blood pressure (BP) measurements allow better control of hypertension. Current measurements rely on cuff-based devices. The aim of the present study was to compare BP measurements using a novel cuff-less photoplethysmography-based device to a standard sphygmomanometer device. Males and females were recruited ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-73172-3

    authors: Nachman D,Gepner Y,Goldstein N,Kabakov E,Ishay AB,Littman R,Azmon Y,Jaffe E,Eisenkraft A

    更新日期:2020-09-30 00:00:00

  • Strain-induced phase transition and electron spin-polarization in graphene spirals.

    abstract::Spin-polarized triangular graphene nanoflakes (t-GNFs) serve as ideal building blocks for the long-desired ferromagnetic graphene superlattices, but they are always assembled to planar structures which reduce its mechanical properties. Here, by joining t-GNFs in a spiral way, we propose one-dimensional graphene spiral...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep05699

    authors: Zhang X,Zhao M

    更新日期:2014-07-16 00:00:00

  • New information of dopaminergic agents based on quantum chemistry calculations.

    abstract::Dopamine is an important neurotransmitter that plays a key role in a wide range of both locomotive and cognitive functions in humans. Disturbances on the dopaminergic system cause, among others, psychosis, Parkinson's disease and Huntington's disease. Antipsychotics are drugs that interact primarily with the dopamine ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-78446-4

    authors: Goode-Romero G,Winnberg U,Domínguez L,Ibarra IA,Vargas R,Winnberg E,Martínez A

    更新日期:2020-12-09 00:00:00

  • Author Correction: Uncovering miRNAs involved in crosstalk between nutrient deficiencies in Arabidopsis.

    abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

    journal_title:Scientific reports

    pub_type: 已发布勘误

    doi:10.1038/s41598-020-62901-3

    authors: Liang G,Ai Q,Yu D

    更新日期:2020-04-20 00:00:00

  • Hybridization between alien species Rumex obtusifolius and closely related native vulnerable species R. longifolius in a mountain tourist destination.

    abstract::Alien species expand their distribution by transportation network development. Hybridization between alien species Rumex obtusifolius and closely related native vulnerable species R. longifolius was examined in a mountain tourist destination in central Japan. The three taxa were morphologically identified in the field...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep13898

    authors: Takahashi K,Hanyu M

    更新日期:2015-09-10 00:00:00

  • Sex Ratio Elasticity Influences the Selection of Sex Ratio Strategy.

    abstract::There are three sex ratio strategies (SRS) in nature-male-biased sex ratio, female-biased sex ratio and, equal sex ratio. It was R. A. Fisher who first explained why most species in nature display a sex ratio of ½. Consequent SRS theories such as Hamilton's local mate competition (LMC) and Clark's local resource compe...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep39807

    authors: Wang Y,Wang R,Li Y,Sam Ma Z

    更新日期:2016-12-23 00:00:00

  • Region-specific growth restriction of brain following preterm birth.

    abstract::Regional brain sizes of very-preterm infants at term-equivalent age differ from those of term-born peers, which have been linked with later cognitive impairments. However, dependence of regional brain volume loss on gestational age has not been studied in detail. To investigate the spatial pattern of brain growth in n...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep33995

    authors: Iwata S,Katayama R,Kinoshita M,Saikusa M,Araki Y,Takashima S,Abe T,Iwata O

    更新日期:2016-09-23 00:00:00

  • Principles and development of collagen-mediated tissue fusion induced by laser irradiation.

    abstract::The mechanism underlying tissue fusion mediated by laser irradiation remains unclear. We clarify the mechanisms underlying laser-mediated tissue fusion using a novel model. Microscopic examinations of morphological changes within the adventitia of a bovine carotid artery and a collagen sheet prepared from bovine dermi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-45486-4

    authors: Sasaki S,Ikeda T,Okihara SI,Nishimura S,Nakadate R,Saeki H,Oki E,Mori M,Hashizume M,Maehara Y

    更新日期:2019-06-28 00:00:00

  • Dynamic representation of time in brain states.

    abstract::The ability to process time on the scale of milliseconds and seconds is essential for behaviour. A growing number of studies have started to focus on brain dynamics as a mechanism for temporal encoding. Although there is growing evidence in favour of this view from computational and in vitro studies, there is still a ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep46053

    authors: Bueno FD,Morita VC,de Camargo RY,Reyes MB,Caetano MS,Cravo AM

    更新日期:2017-04-10 00:00:00

  • Predicting global invasion risks: a management tool to prevent future introductions.

    abstract::Predicting regions at risk from introductions of non-native species and the subsequent invasions is a fundamental aspect of horizon scanning activities that enable the development of more effective preventative actions and planning of management measures. The Asian cyprinid fish topmouth gudgeon Pseudorasbora parva ha...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep26316

    authors: Fletcher DH,Gillingham PK,Britton JR,Blanchet S,Gozlan RE

    更新日期:2016-05-20 00:00:00

  • Inductively actuated micro needles for on-demand intracellular delivery.

    abstract::Methods that provide controlled influx of molecules into cells are of critical importance for uncovering cellular mechanisms, drug development and synthetic biology. However, reliable intracellular delivery without adversely affecting the cells is a major challenge. We developed a platform for on-demand intracellular ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-28194-3

    authors: Kavaldzhiev MN,Perez JE,Sougrat R,Bergam P,Ravasi T,Kosel J

    更新日期:2018-07-02 00:00:00

  • PKC-ѳ is dispensable for OX40L-induced TCR-independent Treg proliferation but contributes by enabling IL-2 production from effector T-cells.

    abstract::We have previously shown that OX40L/OX40 interaction is critical for TCR-independent selective proliferation of Foxp3+ Tregs, but not Foxp3- effector T-cells (Teff), when CD4+ T-cells are co-cultured with GM-CSF derived bone marrow dendritic cells (G-BMDCs). Events downstream of OX40L/OX40 interaction in Tregs respons...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-05254-8

    authors: Alharshawi K,Marinelarena A,Kumar P,El-Sayed O,Bhattacharya P,Sun Z,Epstein AL,Maker AV,Prabhakar BS

    更新日期:2017-07-26 00:00:00

  • Differential interactions of bacterial lipopolysaccharides with lipid membranes: implications for TRPA1-mediated chemosensation.

    abstract::Bacterial lipopolysaccharides (LPS) activate the TRPA1 cation channels in sensory neurons, leading to acute pain and inflammation in mice and to aversive behaviors in fruit flies. However, the precise mechanisms underlying this effect remain elusive. Here we assessed the hypothesis that TRPA1 is activated by mechanica...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-30534-2

    authors: Startek JB,Talavera K,Voets T,Alpizar YA

    更新日期:2018-08-13 00:00:00

  • Heat-killed Lactobacillus casei confers broad protection against influenza A virus primary infection and develops heterosubtypic immunity against future secondary infection.

    abstract::Lactic acid bacteria (LAB) are the common probiotics. Here, we investigated the antiviral protective effects of heat-killed LAB strain Lactobacillus casei DK128 (DK128) on influenza viruses. Intranasal treatment of mice with DK128 conferred protection against different subtypes of influenza viruses by lessening weight...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-17487-8

    authors: Jung YJ,Lee YT,Ngo VL,Cho YH,Ko EJ,Hong SM,Kim KH,Jang JH,Oh JS,Park MK,Kim CH,Sun J,Kang SM

    更新日期:2017-12-12 00:00:00

  • Reconstruction of forest dynamics in the Western Palaearctic based on phylogeographic analysis of the ringlet butterfly Erebia aethiops.

    abstract::Glacial refugia are centers of high biodiversity. Therefore, knowledge on their locations and reactions of associated populations and landscapes to climatic changes is crucial for conservation management. We here investigated the biogeography of a butterfly species linked to open forest habitats. Using mitochondrial a...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-79376-x

    authors: Wendt M,Husemann M,Kramp K,Schmitt T

    更新日期:2021-01-08 00:00:00

  • Effects of 8-week sensory electrical stimulation combined with motor training on EEG-EMG coherence and motor function in individuals with stroke.

    abstract::The peripheral sensory system is critical to regulating motor plasticity and motor recovery. Peripheral electrical stimulation (ES) can generate constant and adequate sensory input to influence the excitability of the motor cortex. The aim of this proof of concept study was to assess whether ES prior to each hand func...

    journal_title:Scientific reports

    pub_type: 杂志文章,随机对照试验

    doi:10.1038/s41598-018-27553-4

    authors: Pan LH,Yang WW,Kao CL,Tsai MW,Wei SH,Fregni F,Chen VC,Chou LW

    更新日期:2018-06-15 00:00:00

  • Bistable behaviour and medium-dependent post-translational regulation of the tryptophanase operon regulatory pathway in Echerichia coli.

    abstract::The present work is aimed at studying the dynamic behaviour of the tryptopnanase (tna) operon, which encodes the proteins necessary to uptake and metabolise tryptophan to use it as a carbon source in the absence of glucose. To this end, we designed a micro-bioreactor capable of driving a bacterial culture to a station...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-41856-0

    authors: Orozco-Gómez DI,Sosa-Hernández JE,Gallardo-Navarro ÓA,Santana-Solano J,Santillán M

    更新日期:2019-04-01 00:00:00

  • Knockdown of a cellulose synthase gene BoiCesA affects the leaf anatomy, cellulose content and salt tolerance in broccoli.

    abstract::Cellulose is the major component of cell wall materials. A 300 bp specific fragment from the cDNA fragment was chosen to insert into vector pFGC1008 at forward and reverse orientations to construct the recombinant RNAi vector. Knockdown of BoiCesA caused "dwarf" phenotype with smaller leaves and a loss of the content ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep41397

    authors: Li S,Zhang L,Wang Y,Xu F,Liu M,Lin P,Ren S,Ma R,Guo YD

    更新日期:2017-02-07 00:00:00

  • Organ-specific transcriptome profiling of metabolic and pigment biosynthesis pathways in the floral ornamental progenitor species Anthurium amnicola Dressler.

    abstract::Anthurium amnicola Dressler possesses a number of desirable and novel ornamental traits such as a purple-colored upright spathe, profuse flowering, and floral scent, some of which have been introgressed into modern Anthurium cultivars. As a first step in identifying genes associated with these traits, the transcriptom...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-00808-2

    authors: Suzuki JY,Amore TD,Calla B,Palmer NA,Scully ED,Sattler SE,Sarath G,Lichty JS,Myers RY,Keith LM,Matsumoto TK,Geib SM

    更新日期:2017-05-04 00:00:00

  • Neurotransmitters and neuropeptides in gonadal steroid receptor-expressing cells in medial preoptic area subregions of the male mouse.

    abstract::Testosterone is involved in male sexual, parental and aggressive behaviors through the androgen receptor (AR) and estrogen receptor (ER) α expressed in the brain. Although several studies have demonstrated that ERα and AR in the medial preoptic area (MPOA) are required for exhibiting sexual and aggressive behaviors of...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-10213-4

    authors: Tsuneoka Y,Yoshida S,Takase K,Oda S,Kuroda M,Funato H

    更新日期:2017-08-29 00:00:00

  • The Multiple DSF-family QS Signals are Synthesized from Carbohydrate and Branched-chain Amino Acids via the FAS Elongation Cycle.

    abstract::Members of the diffusible signal factor (DSF) family are a novel class of quorum sensing (QS) signals in diverse Gram-negative bacteria. Although previous studies have identified RpfF as a key enzyme for the biosynthesis of DSF family signals, many questions in their biosynthesis remain to be addressed. In this study ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep13294

    authors: Zhou L,Yu Y,Chen X,Diab AA,Ruan L,He J,Wang H,He YW

    更新日期:2015-08-20 00:00:00

  • The Co-operation of RUNX1 with LDB1, CDK9 and BRD4 Drives Transcription Factor Complex Relocation During Haematopoietic Specification.

    abstract::Haematopoietic cells arise from endothelial cells within the dorsal aorta of the embryo via a process called the endothelial-haematopoietic transition (EHT). This process crucially depends on the transcription factor RUNX1 which rapidly activates the expression of genes essential for haematopoietic development. Using ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-28506-7

    authors: Gilmour J,Assi SA,Noailles L,Lichtinger M,Obier N,Bonifer C

    更新日期:2018-07-10 00:00:00

  • Compensatory T-type Ca2+ channel activity alters D2-autoreceptor responses of Substantia nigra dopamine neurons from Cav1.3 L-type Ca2+ channel KO mice.

    abstract::The preferential degeneration of Substantia nigra dopamine midbrain neurons (SN DA) causes the motor-symptoms of Parkinson's disease (PD). Voltage-gated L-type calcium channels (LTCCs), especially the Cav1.3-subtype, generate an activity-related oscillatory Ca(2+) burden in SN DA neurons, contributing to their degener...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep13688

    authors: Poetschke C,Dragicevic E,Duda J,Benkert J,Dougalis A,DeZio R,Snutch TP,Striessnig J,Liss B

    更新日期:2015-09-18 00:00:00

  • Atlantic Deep-water Response to the Early Pliocene Shoaling of the Central American Seaway.

    abstract::The early Pliocene shoaling of the Central American Seaway (CAS), ~4.7-4.2 million years ago (mega annum-Ma), is thought to have strengthened Atlantic Meridional Overturning Circulation (AMOC). The associated increase in northward flux of heat and moisture may have significantly influenced the evolution of Pliocene cl...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep12252

    authors: Bell DB,Jung SJ,Kroon D,Hodell DA,Lourens LJ,Raymo ME

    更新日期:2015-07-20 00:00:00

  • Continuous and automatic mortality risk prediction using vital signs in the intensive care unit: a hybrid neural network approach.

    abstract::Mortality risk prediction can greatly improve the utilization of resources in intensive care units (ICUs). Existing schemes in ICUs today require laborious manual input of many complex parameters. In this work, we present a scheme that uses variations in vital signs over a 24-h period to make mortality risk assessment...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-78184-7

    authors: Baker S,Xiang W,Atkinson I

    更新日期:2020-12-04 00:00:00

  • Evidence of Enriched, Hadean Mantle Reservoir from 4.2-4.0 Ga zircon xenocrysts from Paleoarchean TTGs of the Singhbhum Craton, Eastern India.

    abstract::Sensitive High-Resolution Ion Microprobe (SHRIMP) U-Pb analyses of zircons from Paleoarchean (~3.4 Ga) tonalite-gneiss called the Older Metamorphic Tonalitic Gneiss (OMTG) from the Champua area of the Singhbhum Craton, India, reveal 4.24-4.03 Ga xenocrystic zircons, suggesting that the OMTG records the hitherto unknow...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-25494-6

    authors: Chaudhuri T,Wan Y,Mazumder R,Ma M,Liu D

    更新日期:2018-05-04 00:00:00