Surnames and cancer genes.

abstract：:The polymorphism of human mitochondrial DNA (mtDNA) was studied in 118 unrelated Greeks (from northern Greece) using total blood cell DNA and the restriction enzymes HpaI, BamHI, HaeII, MspI, AvaII, and HincII. One new morph was identified for MspI (named MspI morph 18Gr) and is the result of a mutation in a previousl...

journal_title：Human biology

authors： Astrinidis A,Kouvatsi A

更新日期：1994-08-01 00:00:00

abstract：:Viewed as a biological concept, sexual dimorphism does not appear to motivate debate. However, with the aim of measuring such dimorphism, several indexes have been proposed, and not all of them have been regarded as equally reliable by the biological community. The main divergence between the indexes is that their def...

journal_title：Human biology

authors： Ipiña SL,Durand AI

更新日期：2010-04-01 00:00:00

abstract：:Mutations in the GJB2 gene are a major cause of congenital deafness. One specific mutation, the 35delG mutation, has accounted for most of the GJB2 mutations detected in European populations and is one of the most frequent disease mutations identified so far. We evaluated the frequency of the 35delG mutation in DNA sa...

journal_title：Human biology

authors： Oliveira CA,Alexandrino F,Abe-Sandes K,Silva WA Jr,Maciel-Guerra AT,Magna LA,Sartorato EL

更新日期：2004-04-01 00:00:00

abstract：:A reanalysis of the family growth study of Pearson and Lee (1903) leads to an explanation of the inheritance of height other than the one that has been offered until now. By acknowledging that the father may be incorrectly identified, this new analysis provides a more relevant explanation of the data: it fits parallel...

journal_title：Human biology

authors： Clemons T

更新日期：2000-06-01 00:00:00

abstract：:Cross-cultural studies of sex-specific mortality indicate that, whereas males experience their greatest mortality in industrialized societies, females experience their greatest mortality in populations with low life expectancy. The higher mortality of females in low-life-expectancy communities has been interpreted as ...

journal_title：Human biology

authors： Madrigal L

更新日期：1992-04-01 00:00:00

abstract：:The method of isonymy, developed by Crow and Mange for estimating inbreeding from surname frequencies, requires an assumption that has not been appreciated: It is necessary to assume that all males in some ancestral generation, the founding stock, had unique surnames. Because this assumption is seldom justified in rea...

journal_title：Human biology

authors： Rogers AR

更新日期：1991-10-01 00:00:00

abstract：:Cytochrome 1A1 (CYP1A1), glutathione transferase M1 (GSTM1), and glutathione transferase T1 (GSTT1) catalyze the bioactivation and detoxification of a wide variety of xenobiotic compounds that are mutagenic and/or carcinogenic (e.g., polycyclic aromatic hydrocarbons). Genetic polymorphisms of these metabolizing enzyme...

journal_title：Human biology

authors： Pérez-Morales R,Castro-Hernández C,Gonsebatt ME,Rubio J

更新日期：2008-08-01 00:00:00

abstract：:A major goal in anthropological genetics is the assessment of the effects of different microevolutionary forces. Harpending and Ward (1982) developed a model that aids in this effort by comparing observed and expected heterozygosity within populations in a local region. The expected heterozygosity within a population ...

journal_title：Human biology

authors： Relethford JH,Blangero J

更新日期：1990-02-01 00:00:00

abstract：:The primary purpose of this research is to collate, compare, and discuss the presently available data for head and face dimensions among Korean and Japanese ethnic groups. Classification of Korean male and female head and face types is simpler than classification of Japanese subjects. Male groups have more statistical...

journal_title：Human biology

authors： Lee HJ,Park SJ

更新日期：2008-06-01 00:00:00

abstract：:The 657del5 mutation of the NBS1 gene has been demonstrated in most patients with Nijmegen breakage syndrome (NBS). We identified four Turkish families in which probands were diagnosed as having NBS and found to be homozygous for the 657del5 mutation. The 657del5 allele in the four Turkish families had a single origin...

journal_title：Human biology

authors： Tekin M,Akcayoz D,Ucar C,Gulen H,Akar N

更新日期：2005-06-01 00:00:00

abstract：:The Muslim population of India is known for its historical and socioreligious significance. Literature on the genetic structure of this segment of India's population is scanty. Therefore we have investigated the allele frequency distribution of haptoglobin (HP) and transferrin (TF) phenotypes among the Muslims to expl...

journal_title：Human biology

authors： Ahmad R,Alam A,Fatima F,Hasnain AU

更新日期：2008-10-01 00:00:00

abstract：:90 nulliparous white female college students, selected from 2 undergraduate introductory courses at Kansas University, participated in a cross-sectional study designed to compare the fat distribution of oral contraceptive (OC) users to that of nonusers matched for height and weight. The subjects ranged in age from 18...

journal_title：Human biology

authors： Litchfield RE,Grunewald KK

更新日期：1988-10-01 00:00:00

abstract：:A Buryat population consisting of seven tribal groups in eastern Mongolia has been screened to determine the frequency distribution of different apolipoprotein E and H alleles (APOE and APOH, genes) coding for common isoforms and their association with quantitative plasma lipid levels. Allele frequencies at the APOE l...

journal_title：Human biology

authors： Tsunoda K,Harihara S,Dashnyam B,Semjidmaa D,Yamaguchi Y,Tanabe Y,Sakai N,Sato A,Sato K

更新日期：2002-10-01 00:00:00

abstract：:GM and KM immunoglobulin (Ig) allotypes have been tested in 310 autochthonous Basques from the three subpopulations of Vizcaya, Guipúzcoa, and Alava, Spain. They are compared with allotypes occurring in autochthonous French Basques, some Pyrenean subpopulations in France, and European populations. The analysis suggest...

journal_title：Human biology

authors： Calderón R,Vidales C,Peña JA,Perez-Miranda A,Dugoujon JM

更新日期：1998-08-01 00:00:00

abstract：:We analyze the possible effect of gene flow on the genetic structure of present-day Mexicans. For this purpose we reviewed previous admixture estimates for various Indian and Mestizo groups. Several facts seem clear: (1) There are no pure Indian groups in Mexico, because all Indian groups show variable degrees of admi...

journal_title：Human biology

authors： Lisker R,Ramírez E,Babinsky V

更新日期：1996-06-01 00:00:00

abstract：:The Norse and Celtic contributions to the founding population of Iceland have been estimated previously on a pan-Icelandic basis using gene frequency data for the entire island. Accounts of the settlement of Iceland, however, suggest that different regions received different proportions of Norse and Celtic settlers, i...

journal_title：Human biology

authors： Williams JT

更新日期：1993-04-01 00:00:00

abstract：:"Pygmy populations" are recognized in several places over the world, especially in Western Africa and in Southeast Asia (Philippine "negritos," for instance). Broadly defined as "small-bodied Homo sapiens" (compared with neighboring populations), their origins and the nature of the processes involved in the maintenanc...

journal_title：Human biology

authors： Détroit F,Corny J,Dizon EZ,Mijares AS

更新日期：2013-02-01 00:00:00

abstract：:The major histocompatibility complex is directly involved in the immune response, and thus the genes coding for its proteins are useful markers for the study of genetic diversity, susceptibility to disease (autoimmunity and infections), transplant medicine, and pharmacogenetics, among others. The polymorphism of the s...

journal_title：Human biology

authors： Cortés EDJ,Sieck MAC,Perea AJA,Medrano RMM,Jaime AB,Martínez PE,Zúñiga J,Alonzo VA,Granados J,Barquera R

更新日期：2017-07-01 00:00:00

abstract：:Polymorphisms in the interleukin-6 promoter region have been associated with diseases. In this study we investigated the -634G/C and -174G/C IL-6 promoter polymorphisms in three Brazilian ethnic groups. We verified that the allele frequencies of the two polymorphisms and haplotype frequencies varied significantly betw...

journal_title：Human biology

authors： Gadelha SR,Alcantara LC,Costa GC,Rios DL,Galvão-Castro B

更新日期：2005-08-01 00:00:00

abstract：:We carried out an exploratory historical biology study using temporally distinguished groups of predynastic-Early Dynastic male crania from the region of Upper Egypt. The objectives were, first, to determine the overall pattern of phenetic affinity between temporally sequential series and in relation to the earliest s...

journal_title：Human biology

authors： Keita SO,Boyce AJ

更新日期：2008-04-01 00:00:00

abstract：:Dermatoglyphic traits have been used to assess population affinities and structure. Here, we describe the digital patterns of four Eskimo populations from Alaska: two Yupik-speaking villages from St. Lawrence Island and two Inupik groups presently residing on mainland Alaska. For a broader evolutionary perspective, th...

journal_title：Human biology

authors： Crawford MH,Duggirala R

更新日期：1992-10-01 00:00:00

abstract：:The amiloride-sensitive epithelial sodium channel is a highly selective sodium channel that constitutes the rate-limiting step of sodium reabsorption in distal nephrons. It consists of at least 3 subunits (alpha, beta, and gamma) of similar structure and plays an important role in sodium and fluid homeostasis. Defects...

journal_title：Human biology

authors： Xu X,Niu T,Chen C,Yang J,Fang Z,Xu X

更新日期：1999-10-01 00:00:00

abstract：:Details of the population pyramid of living Herero and Mbanderu of Botswana suggest that infant and childhood mortality of males has been substantially greater than that of females. Direct tests from reproductive histories show that the hazard ratio is approximately 3 to 1 in favor of female survival in infancy and 2 ...

journal_title：Human biology

authors： Harpending HC,Pennington R

更新日期：1991-06-01 00:00:00

abstract：:We summarize several studies, from the last 10 years, of temporal changes and rural-urban differences in the risk factors of cardiovascular disease (CVD) in China to indicate the influences of economic modernization. Two national blood pressure surveys have shown that the prevalence of hypertension increased from 5.1%...

journal_title：Human biology

authors： Zhai S,McGarvey ST

更新日期：1992-12-01 00:00:00

abstract：:Birth weight is the single most significant determinant of infant mortality and the chances of a newborn to experience healthy development. Low birth weight also appears to be related to higher risks of several important chronic conditions, such as ischemic heart disease, non-insulin-dependent diabetes, and cancer in ...

journal_title：Human biology

authors： Chodick G,Flash S,Deoitch Y,Shalev V

更新日期：2009-08-01 00:00:00

abstract：:Population substructure and biological differentiation was studied among the Golla, a pastoral caste living in the southern areas of Andhra Pradesh (AP) in India, using 11 anthropometric measurements and 20 quantitative dermatoglyphic variables. The data were collected from a sample of 334 adult males drawn from 30 vi...

journal_title：Human biology

authors： Reddy BM,Pfeffer A,Crawford MH,Langstieh BT

更新日期：2001-04-01 00:00:00

abstract：:The genetic surveys of the population of Britain conducted by Weale et al. and Capelli et al. produced estimates of the Germani immigration into Britain during the early Anglo-Saxon period, c.430-c.730. These estimates are considerably higher than the estimates of archaeologists. A possible explanation suggests that a...

journal_title：Human biology

authors： Pattison JE

更新日期：2011-12-01 00:00:00

abstract：:In this paper I propose that evolutionary demography and associated theory from human behavioral ecology provide a strong basis for explaining the available evidence for the patterns observed in the first agricultural settlement of Europe in the 7th-5th millennium cal. BC, linking together a variety of what have previ...

journal_title：Human biology

authors： Shennan S

更新日期：2009-04-01 00:00:00

abstract：:HLA-DQB1*0302 allele frequency is increased in liver graft recipients with acute rejection. We investigated polymorphism in the upstream regulatory regions (URRs) of the DQB1 gene to determine whether polymorphism in the DQB1 promoter region influences liver graft acceptance. A combination of typing protocols based on...

journal_title：Human biology

authors： Muro M,Herrero N,Marin L,Torío A,Minguela A,Sánchez-Bueno F,García-Alonso AM,Alvarez-López MR

更新日期：2001-12-01 00:00:00

abstract：:The joint distributions of phenotypes from the apolipoprotein E gene (APOE) and from a closely linked restriction site polymorphism at the apolipoprotein C1 locus (APOC1) were studied in population samples from Portugal and São Tomé e Príncipe (Gulf of Guinea), a former Portuguese colony that was originally populated ...

journal_title：Human biology

authors： Seixas S,Trovoada MJ,Rocha J

更新日期：1999-12-01 00:00:00