当前位置： SCI文献检索 > JOURNAL OF ASSISTED REPRODUCTION AND GENETICS期刊下所有文献 > Altered bivalent positioning in metaphase I human spermatocytes from Robertsonian translocation carriers.

Altered bivalent positioning in metaphase I human spermatocytes from Robertsonian translocation carriers.

Abstract：

PURPOSE:The study aims to determine whether there is an altered bivalent positioning in metaphase I human spermatocytes from Robertsonian translocation carriers. METHODS:Metaphase I human spermatocytes from three 45,XY,der(13;14)(q10;q10) individuals and a 45,XY,der(14;15)(q10;q10) individual were analyzed. Proximity relationships of bivalents were established by analyzing meiotic preparations combining Leishman staining and multiplex-FISH procedures. Poisson regression model was used to determine proximity frequencies between bivalents and to assess associations with chromosome size, gene density, acrocentric morphology, and chromosomes with heterochromatic blocks. The hierarchical cluster Ward method was used to characterize the groups of bivalents with preferred proximities in a cluster analysis. Bivalent groups obtained were individually compared with those obtained in normal karyotype individuals evaluated in a previous study. RESULTS:A total of 1288 bivalents were examined, giving a total of 2289 proximity data. Only four positive significant proximities were detected for each type of Robertsonian translocation. Significant bivalent associations were only observed by small-size chromosomes for MI,22,XY,III(13q14q). These results were clearly divergent from 46,XY individuals. Moreover, cluster analysis revealed that about 30 % of the bivalents showed changes in their proximity relationships in metaphase I. CONCLUSIONS:The territorial organization of bivalents in metaphase I human spermatocytes changes in the presence of a Robertsonian translocation.

journal_name

J Assist Reprod Genet

journal_title

Journal of assisted reproduction and genetics

authors

Solé M,Blanco J,Valero O,Vergés L,Vidal F,Sarrate Z

doi

10.1007/s10815-016-0809-y

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

131-138

issue

1

eissn

1058-0468

issn

1573-7330

pii

10.1007/s10815-016-0809-y

journal_volume

34

pub_type

杂志文章

相关文献

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS文献大全
  • "One for Sorrow, Two for Joy?": American embryo transfer guideline recommendations, practices, and outcomes for gestational surrogate patients.

    abstract：:In January 2016, Melissa Cook, a California gestational surrogate experiencing a multiple-birth pregnancy following the in vitro fertilization (IVF) transfer of three embryos comprised of donor eggs and sperm provided by the intended father, went to the media when the intended father requested that she undergo a fetal...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,评审

    doi：10.1007/s10815-017-0885-7

    authors： White PM

    更新日期：2017-04-01 00:00:00

  • Zona thinning with noncontact diode laser in patients aged < or = 37 years with no previous failure of implantation: a prospective randomized study.

    abstract：PURPOSE:Zona thinning (ZT) is a technique used to improve pregnancy rates among patients > or = 38 years old and/or patients presenting previous implantation failure. The objective of the study was to determine whether ZT has a beneficial effect on patients younger than 37 years who are undergoing the first ICSI attemp...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1023/a:1026481729632

    authors： Baruffi RL,Mauri AL,Petersen CG,Ferreira RC,Coelho J,Franco JG Jr

    更新日期：2000-11-01 00:00:00

  • G9a co-localized with histone H3 lysine 9 monomethylation but not dimethylation in a nuclear membrane-dependent manner during mouse preimplantation embryo development.

    abstract：PURPOSE:Histone H3 lysine 9 (H3K9) methylation plays an important role in the regulation of preimplantation embryo development. G9a has been reported to be a major H3K9mono (m1)/dimethylation(m2) methyltransferase and to contain nuclear localization signals. This study was performed to investigate the correlation betwe...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-012-9911-y

    authors： Li B,Tang N,Chen S,Li X,Huang X,Wang X,Sun F

    更新日期：2013-03-01 00:00:00

  • Ovulation triggering in clomiphene citrate-stimulated cycles: human chorionic gonadotropin versus a gonadotropin releasing hormone agonist.

    abstract：PURPOSE:To compare the use of human chorionic gonadotropin (hCG) to a gonadotropin releasing hormone (GnRH) agonist, nafarelin, in initiating ovulation and supporting the luteal phase after priming with clomiphene. METHODS:In 26 infertile women 50 mg clomiphene citrate produced a preovulatory-size follicle. Then, 11 w...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/BF02211793

    authors： Schmidt-Sarosi C,Kaplan DR,Sarosi P,Essig MN,Licciardi FL,Keltz M,Levitz M

    更新日期：1995-03-01 00:00:00

  • Leukemia inhibitory factor expression in different endometrial locations between fertile and infertile women throughout different menstrual phases.

    abstract：PURPOSE:The purpose was to demonstrate the leukemia inhibitory factor (LIF) expression in different endometrial locations between fertile and infertile women throughout different menstrual phases. The relationship between progesterone level and LIF expression were evaluated. METHODS:Endometrial biopsies were performed...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1023/a:1009457016871

    authors： Tsai HD,Chang CC,Hsieh YY,Lo HY

    更新日期：2000-09-01 00:00:00

  • Sperm meiotic segregation, aneuploidy and high risk of delivering an affected offspring in carriers of non-Robertsonian translocation t(13;15).

    abstract：PURPOSE:To determine the percentage of unbalanced spermatozoa and an interchromosomal effect in two carriers of balanced translocations t(13;15)(q32;q26) and t(13;15)(q32;p11.2). METHODS:Sperm nuclei analysis by fluorescent in situ hybridization for detection of percentage of unbalanced spermatozoa and sperm with diso...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-012-9767-1

    authors： Kasikova K,Vozdova M,Prinosilova P,Gaillyova R,Hanakova M,Rubes J

    更新日期：2012-07-01 00:00:00

  • Preimplantation genetic diagnosis of inherited cancer: familial adenomatous polyposis coli.

    abstract：PURPOSE:Our purpose was to achieve preimplantation genetic diagnosis (PGD) of the dominant cancer predisposition syndrome, familial adenomatous polyposis coli (FAPC), as an alternative to prenatal diagnosis. METHODS:The affected patient was superovulated and oocytes were retrieved and fertilized by intracytoplasmic sp...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1023/a:1023008921386

    authors： Ao A,Wells D,Handyside AH,Winston RM,Delhanty JD

    更新日期：1998-03-01 00:00:00

  • The effects of cooling mouse oocytes.

    abstract：:The effects of cooling and warming on meiotic spindles of mouse oocytes have been assessed by transmission electron microscopy. Intact cumulus-oocyte complexes were immediately cooled from 37 to 15, 4, 0, and -7 degrees C (seeding temperature) for 15 min in a programmed biological freezer and fixed at these temperatur...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/BF01203754

    authors： Sathananthan AH,Kirby C,Trounson A,Philipatos D,Shaw J

    更新日期：1992-04-01 00:00:00

  • Behavior of mouse spermatogonial stem-like cells on an electrospun nanofibrillar matrix.

    abstract：PURPOSE:Spermatogonial stem cells are affected by the interactions of extrinsic signals produced by components of the microenvironment niche, in addition to the chemical and physical properties of the extracellular matrix. Therefore, this study was initiated to assess the interaction of these cells on a synthetic nanof...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-012-9916-6

    authors： Shakeri M,Kohram H,Shahverdi A,Shahneh AZ,Tavakolifar F,Pirouz M,Shahrebabak HM,Koruji M,Baharvand H

    更新日期：2013-03-01 00:00:00

  • Eleven healthy live births: a result of simultaneous preimplantation genetic testing of α- and β-double thalassemia and aneuploidy screening.

    abstract：PURPOSE:To evaluate the efficacy of preimplantation genetic testing (PGT) for α- and β-double thalassemia combined with aneuploidy screening using next-generation sequencing (NGS). METHODS:An NGS-based PGT protocol was performed between 2017 and 2018 for twelve couples, each of which carried both α- and β-thalassemia ...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-020-01732-7

    authors： Chen D,Shen X,Wu C,Xu Y,Ding C,Zhang G,Xu Y,Zhou C

    更新日期：2020-03-01 00:00:00

  • The effect of intrafollicular IGF 1 and IGFBP 3 on IVF outcome in patients using different gonadotropins: a prospective study.

    abstract：AIM:To investigate follicular fluid IGF 1, IGFBP 3 and their effects on IVF outcome in patients using different gonadotropins. MATERIALS AND METHODS:This prospective study was performed among 92 IVF patients who were categorized according to IVF pregnancy outcome. Two groups were formed as Group 1 : pregnant, Group 2:...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-011-9543-7

    authors： Genc G,Yilmaz N,Uygur D,Dogan M,Mollamahmutoglu L

    更新日期：2011-05-01 00:00:00

  • Combined intrauterine triplet and ectopic pregnancy following pronuclear embryo transfer in a patient with elevated serum progesterone during ovulation induction.

    abstract：:We present a case of heterotopic pregnancy occurring after ET of pronuclear-stage embryos. This case demonstrates that pronuclear embryos have a good implantation potential and suggests that the potentially adverse effect of high follicular-phase serum progesterone levels on endometrial development might be offset by ...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/BF01212937

    authors： Smith S,Scott L,Hosid S

    更新日期：1993-10-01 00:00:00

  • Development of a high-yield technique to isolate spermatogonial stem cells from porcine testes.

    abstract：PURPOSE:To date, the methods available for isolating spermatogonial stem cells (SSCs) from porcine testicular cells have a low efficiency of cell separating. Therefore, we tried to develop a novel isolation technique with a high-yield cell separating ability to isolate SSCs from porcine testes. METHODS:We confirmed th...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-014-0271-7

    authors： Park MH,Park JE,Kim MS,Lee KY,Park HJ,Yun JI,Choi JH,Lee Es,Lee ST

    更新日期：2014-08-01 00:00:00

  • Serum progesterone before and after human chorionic gonadotropin injection depends on the estradiol response to ovarian hyperstimulation during in vitro fertilization-embryo transfer cycles.

    abstract：PURPOSE:Our purpose was to assess if periovulatory serum progesterone is reflective of ovarian responsiveness in controlled ovarian hyperstimulation (COH). METHODS:One-hundred forty-two in vitro fertilization-embryo transfer cycles in women using GnRH-a suppression and human menopausal gonadotropin (hMG) stimulation w...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1023/a:1020311328182

    authors： Lindheim SR,Cohen MA,Chang PL,Sauer MV

    更新日期：1999-05-01 00:00:00

  • Constitutional complex chromosomal rearrangements in a klinefelter patient: case report and review of literature.

    abstract：BACKGROUNDS:While XXY aneuploidy is the most common disorder of sex chromosomes in men, complex chromosomal rearrangements (CCRs) are rare in humans. CASE DESCRIPTION:Here we describe clinical and cytogenetic findings in a male referred to our cytogenetic laboratory by an infertility clinic. The patient's age was 35 a...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,评审

    doi：10.1007/s10815-012-9725-y

    authors： Mahjoubi F,Razazian F

    更新日期：2012-05-01 00:00:00

  • The association between the oocyte pool and aneuploidy: a comparative study of the reproductive potential of young and aged mice.

    abstract：PURPOSE:The present study examined the effect of aging on female reproductive potential. METHODS:Six-week-old and 9-month-old CD1 mice were referred to as the 'young' and 'aged' groups, respectively. Oocytes were collected after superovulation, and their viability were compared using parthenogenetic activation. The an...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-013-0160-5

    authors： Fu X,Cheng J,Hou Y,Zhu S

    更新日期：2014-03-01 00:00:00

  • Cumulus cell pappalysin-1, luteinizing hormone/choriogonadotropin receptor, amphiregulin and hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 mRNA levels associate with oocyte developmental competence and embryo outcomes.

    abstract：PURPOSE:To determine whether a selected set of mRNA biomarkers expressed in individual cumulus granulosa cell (CC) masses show association with oocyte developmental competence, embryo ploidy status, and embryo outcomes. METHODS:This prospective observational cohort pilot study assessed levels of mRNA biomarkers in 163...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-019-01489-8

    authors： Kordus RJ,Hossain A,Corso MC,Chakraborty H,Whitman-Elia GF,LaVoie HA

    更新日期：2019-07-01 00:00:00

  • Intracytoplasmic injection using spermatids and subsequent pregnancies: round versus elongated spermatids.

    abstract：:The purpose of this clinical trial study was to report the outcome of intracytoplasmic injection of round (RS) and elongated (ES) spermatids retrieved from the testis of nonobstructive men. Seven and three cycles using RS and ES injections were performed, respectively. Only one cycle utilizing the late stage of ES (Sd...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 临床试验,杂志文章

    doi：10.1023/a:1014447731630

    authors： Khalili MA,Aflatoonian A,Zavos PM

    更新日期：2002-02-01 00:00:00

  • Sperm DNA integrity assays: diagnostic and prognostic challenges and implications in management of infertility.

    abstract：:Sperm is not a simple carrier of paternal genetic information but its role extends clearly beyond fertilization. Integrity of sperm genome is an essential pre-requisite for birth of healthy offspring and evaluation of sperm should entail DNA integrity analysis. DNA integrity analysis is a better diagnostic and prognos...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,评审

    doi：10.1007/s10815-011-9631-8

    authors： Shamsi MB,Imam SN,Dada R

    更新日期：2011-11-01 00:00:00

  • Sequential FISH allows the determination of the segregation outcome and the presence of numerical anomalies in spermatozoa from a t(1;8;2)(q42;p21;p15) carrier.

    abstract：PURPOSE:To find out the meiotic segregation behaviour of the t(1;8;2)(q42;p21;p15), to evaluate the occurrence of interchromosomal effects, and to determine whether there is an accumulation of unbalanced products in aneuploid/diploid gametes. METHODS:A sequential FISH protocol based on two successive hybridization rou...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-013-0063-5

    authors： Godo A,Blanco J,Vidal F,Parriego M,Boada M,Anton E

    更新日期：2013-09-01 00:00:00

  • Connections between preimplantation embryo physiology and culture.

    abstract：PURPOSE:To review the history of experimental embryo culture and how culture media that permitted complete preimplantation development in vitro were first discovered, and the physiological insights gained. METHODS:This article reviews the history of in vitro mammalian embryo culture, in particular the efforts that led...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 历史文章,杂志文章,评审

    doi：10.1007/s10815-013-0095-x

    authors： Baltz JM

    更新日期：2013-08-01 00:00:00

  • Prognostic value of objective semen parameters in an in vitro fertilization program.

    abstract：PURPOSE:The basic semen parameters seem to have a limited predictive value in male fertility. Could other objective sperm analyses be helpful in the choice of the most adapted assisted procreation technique? METHODS:This study concerns 78 infertile couples with insemination failures. For each semen, 21 objective param...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/BF02765835

    authors： Wittemer C,Warter S,Ohl J,Sudan B,Mache A,Dellenbach P

    更新日期：1997-07-01 00:00:00

  • Epidermal growth factor (EGF) receptor localization in cultured human granulosa lutein cells and the stimulation of progesterone production by EGF and transforming growth factor-alpha (TGF-alpha).

    abstract：PURPOSE:The purpose of this study was to investigate the expression of EGF receptor (EGF-R) in human granulosa cells undergoing luteinization and progesterone production by these cells in response to EGF an TGF-alpha alone or in combination with luteinizing hormone (LH). Granulosa cells were obtained from IF patients f...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/BF02212900

    authors： Tekpetey FR,Daniel SA,Yuzpe A

    更新日期：1995-11-01 00:00:00

  • Cost-effectiveness of recombinant versus urinary follicle-stimulating hormone in assisted reproduction techniques in the Spanish public health care system.

    abstract：PURPOSE:To evaluate the relative cost-effectiveness of recombinant and urinary follicle-stimulating hormone (FSH) in assisted reproduction techniques in the Spanish National Health Service. METHODS:Markov modelling was used to compare costs and outcomes of three complete treatment cycles using recombinant or urinary F...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1023/a:1024899806149

    authors： Romeu A,Balasch J,Ruiz Balda JA,Barri PN,Daya S,Auray JP,Duru G,Beresniak A,Peinado JA

    更新日期：2003-08-01 00:00:00

  • Nitric oxide modulates mitochondrial activity and apoptosis through protein S-nitrosylation for preimplantation embryo development.

    abstract：PURPOSE:Previous studies reported that patients with endometriosis had excess nitric oxide (NO) in the reproductive tract and poor embryo development in IVF cycles. This study aims to elucidate the effects of NO on early embryo development. METHODS:Zygotes from superovulated B6CBF1 mice were cultured to blastocysts in...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-013-0045-7

    authors： Lee TH,Lee MS,Huang CC,Tsao HM,Lin PM,Ho HN,Shew JY,Yang YS

    更新日期：2013-08-01 00:00:00

  • A chromosome 19 locus positively influences the number of retrieved oocytes during stimulated cycles in Brazilian women.

    abstract：PURPOSE:To evaluate if several genetic loci that are associated with variation in normal menopause age and early menopause can account for a poor response to controlled ovarian stimulation. METHODS:A total of 71 patients age ≤35 years old who were undergoing intracytoplasmic sperm injection were genotyped for four gen...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-012-9735-9

    authors： Setti AS,Cortezzi SS,Figueira Rde C,Martinhago CD,Braga DP,Iaconelli A Jr,Borges E Jr

    更新日期：2012-05-01 00:00:00

  • Male infertility in China: laboratory finding for AZF microdeletions and chromosomal abnormalities in infertile men from Northeastern China.

    abstract：PURPOSES:To investigate the frequencies of AZF microdeletions and chromosomal abnormalities in infertile men from Northeastern China. Moreover, to compare the prevalence of these abnormalities with other countries and regions in the world. METHODS:305 infertile men were enrolled. A complete semen analysis and reproduc...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-010-9420-9

    authors： Wang RX,Fu C,Yang YP,Han RR,Dong Y,Dai RL,Liu RZ

    更新日期：2010-07-01 00:00:00

  • Genotyping single-sperm cells by universal MARSALA enables the acquisition of linkage information for combined pre-implantation genetic diagnosis and genome screening.

    abstract：PURPOSE:This paper aims to investigate the feasibility of performing pre-implantation genetic diagnosis (PGD) and pre-implantation genetic screening (PGS) simultaneously by a universal strategy without the requirement of genotyping relevant affected family members or lengthy preliminary work on linkage analysis. METHO...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-018-1158-9

    authors： Wu H,Shen X,Huang L,Zeng Y,Gao Y,Shao L,Lu B,Zhong Y,Miao B,Xu Y,Wang Y,Li Y,Xiong L,Lu S,Xie XS,Zhou C

    更新日期：2018-06-01 00:00:00

  • An integrated investigation of oocyte developmental competence: expression of key genes in human cumulus cells, morphokinetics of early divisions, blastulation, and euploidy.

    abstract：PURPOSE:To investigate the association of cumulus cell (CC)-related expression of a selected cluster of key genes (PTGS2, CAMK1D, HAS2, STC1, and EFNB2) with embryo development to blastocyst. METHODS:Exploratory study at a private clinic. Eighteen advanced maternal age patients were enrolled (37.3 ± 4.0 years). Sevent...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-019-01410-3

    authors： Scarica C,Cimadomo D,Dovere L,Giancani A,Stoppa M,Capalbo A,Ubaldi FM,Rienzi L,Canipari R

    更新日期：2019-05-01 00:00:00

  • Endogenous LH surge versus hCG as ovulation trigger after low-dose highly purified FSH in IUI: a comparison of 761 cycles.

    abstract：PURPOSE:The results obtained with a protocol consisting of ovarian stimulation with low doses of highly purified FSH (FSH HP), administration of a GnRH analogue to induce an endogenous surge of gonadotropins, and IUI were evaluated. These results were compared with those seen with similar FSH stimulation and hCG admini...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1023/a:1021127410300

    authors： Romeu A,Monzó A,Peiró T,Diez E,Peinado JA,Quintero LA

    更新日期：1997-10-01 00:00:00