Leukemia inhibitory factor expression in different endometrial locations between fertile and infertile women throughout different menstrual phases.

Abstract:

PURPOSE:The purpose was to demonstrate the leukemia inhibitory factor (LIF) expression in different endometrial locations between fertile and infertile women throughout different menstrual phases. The relationship between progesterone level and LIF expression were evaluated. METHODS:Endometrial biopsies were performed on idiopathic infertile and normal fertile women accepted the in follicular, periovulatory, and luteal phases. The luteal progesterone level was measured. Endometrial LIF immunostaining of luminal epithelium, glandular epithelium, and stroma were detected. The relationship between luteal LIF expression and progesterone level was evaluated. RESULTS:Significant LIF expression was noted in the endometrium of fertile women rather than that of infertile women. The LIF expression was highest in the luminal epithelium, moderate in the glandular epithelium, and lowest in the stroma. The luminal and glandular epithelial staining were lowest in follicular phase, moderate in periovulatory phase, and strongest in luteal phase. The stromal LIF presented with a noncyclical manner. The LIF expression is not related with the progesterone level. CONCLUSIONS:Endometrial LIF expression is related to human fertility. Endometrial LIF expression is dependent on cellular localizations and menstrual stages. Stronger LIF expression presents in the endometrial epithelium during luteal phase.

journal_name

J Assist Reprod Genet

authors

Tsai HD,Chang CC,Hsieh YY,Lo HY

doi

10.1023/a:1009457016871

keywords:

subject

Has Abstract

pub_date

2000-09-01 00:00:00

pages

415-8

issue

8

eissn

1058-0468

issn

1573-7330

journal_volume

17

pub_type

杂志文章
  • Sperm chromatin condensation defects, but neither DNA fragmentation nor aneuploidy, are an independent predictor of clinical pregnancy after intracytoplasmic sperm injection.

    abstract:PURPOSE:The impact of sperm DNA damage on intracytoplasmic sperm injection (ICSI) outcomes remains controversial. The purpose of the study was to evaluate the prognostic value of several types of sperm nuclear damage on ICSI clinical pregnancy. METHODS:Our retrospective study included a total of 132 couples who consul...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-019-01471-4

    authors: Bichara C,Berby B,Rives A,Jumeau F,Letailleur M,Setif V,Sibert L,Rondanino C,Rives N

    更新日期:2019-07-01 00:00:00

  • A novel male 2;4;14 complex chromosomal translocation with normal semen parameters but 100% embryonic aneuploidy.

    abstract::We report a case of a couple with a history of six spontaneous miscarriages in which a novel complex chromosomal rearrangement was detected in the male partner who had a totally normal semen analysis. Preimplantation genetic testing of their embryos demonstrated 100% aneuploidy. ...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-018-1126-4

    authors: Mas J,Sabouni R,Bocca S

    更新日期:2018-05-01 00:00:00

  • Predictive value of DNA integrity analysis in idiopathic recurrent pregnancy loss following spontaneous conception.

    abstract:PURPOSE:Standard semen parameters are poor predictors of fertility potential. To date, apart from, paternal karyotyping sperm factors are not evaluated in recurrent pregnancy loss (RPL), only recent studies have emphasized the role of sperm factors in early embryonic development as sperm transcribes genes critical for ...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-012-9801-3

    authors: Kumar K,Deka D,Singh A,Mitra DK,Vanitha BR,Dada R

    更新日期:2012-09-01 00:00:00

  • Association study between FSHR Ala307Thr and Ser680Asn variants and polycystic ovary syndrome (PCOS) in Northern Chinese Han women.

    abstract:BACKGROUND:Polycystic ovary syndrome (PCOS) is a common complex genetic endocrinopathy. It has high heritability, and twin studies indicate that it is a complex polygenic disorder. Searching for major genes of PCOS is crucial to clarify its molecular pathogenesis. A previous genome-wide association study in Chinese wom...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-013-9979-z

    authors: Fu L,Zhang Z,Zhang A,Xu J,Huang X,Zheng Q,Cao Y,Wang L,Du J

    更新日期:2013-06-01 00:00:00

  • Assisted reproduction counseling in women aged 40 and above: a cohort study.

    abstract:PURPOSE:Fertility treatment in women aged ≥40 year old remains difficult and controversial. All available studies in older women report results of one specific method of ART, i.e. IUI, IVF/ICSI or oocyte donation, and success rates are always published per attempt but never per patient. Randomized studies are not avail...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-013-0085-z

    authors: De Brucker M,Tournaye H,Haentjens P,Verheyen G,Collins J,Camus M

    更新日期:2013-11-01 00:00:00

  • Centrifugal pulsing increases the recovery of viable spermatozoa.

    abstract:PURPOSE:Our purpose was to compare the number and quality of spermatozoa recover following the standard centrifugation method with those after pulsing the relative centrifugal field during centrifugation. METHODS:A prospectively controlled in vitro study using ejaculates from 10 healthy sperm donors was undertaken. Nu...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 临床试验,杂志文章

    doi:10.1023/a:1020385411769

    authors: Bielfeld P,Acosta V,Jeyendran RS

    更新日期:1998-11-01 00:00:00

  • Chromosomal abnormalities in couples with recurrent spontaneous miscarriage: a 21-year retrospective study, a report of a novel insertion, and a literature review.

    abstract:PURPOSE:The aim of this study is to evaluate the frequency and nature of chromosomal abnormalities in Moroccan couples with recurrent spontaneous miscarriage (RSM). In addition, the data were compared with those reported elsewhere in order to give a global estimation of chromosomal abnormalities frequencies. METHODS:T...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-018-1373-4

    authors: Elkarhat Z,Kindil Z,Zarouf L,Razoki L,Aboulfaraj J,Elbakay C,Nassereddine S,Nasser B,Barakat A,Rouba H

    更新日期:2019-03-01 00:00:00

  • Relationship between pre-ICSI meiotic spindle angle, ovarian reserve, gonadotropin stimulation, and pregnancy outcomes.

    abstract:PURPOSE:The goals of this study are to analyze the clinical pregnancy rate as a function of the pre-intracytoplasmic sperm injection (ICSI) oocyte spindle angle and determine factors which can be associated with different spindle angles, if clinically relevant. METHODS:Fifty-eight patients, who underwent their first I...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-017-0890-x

    authors: Mahfoudh AM,Moon JH,Henderson S,Garcia-Cerrudo E,Son WY,Dahan MH

    更新日期:2017-05-01 00:00:00

  • Parthenogenetic activation of human oocytes by puromycin.

    abstract:OBJECTIVE:Our objective was to obtain parthenogenetic activation of unfertilized human oocytes by puromycin and to try to use this procedure for cytogenetic purposes. SETTING:The setting was our IVF laboratory. METHODS:Eighty-two spare oocytes from 34 IVF patients were used. In the first series of experiments 39 unfe...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/BF01203955

    authors: De Sutter P,Dozortsev D,Cieslak J,Wolf G,Verlinsky Y,Dyban A

    更新日期:1992-08-01 00:00:00

  • Recurrent complete hydatidiform mole: where we are, is there a safe gestational horizon? Opinion and mini-review.

    abstract::Benign hydatidiform mole, complete or partial, is the most common type of gestational trophoblastic disease (GTD) characterised by excessive trophoblastic proliferation and abnormal embryonic development. Although most complete hydatidiform moles (CHMs) are diploid androgenetic, a few cases of CHMs are biparental, cha...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章,评审

    doi:10.1007/s10815-018-1202-9

    authors: Kalogiannidis I,Kalinderi K,Kalinderis M,Miliaras D,Tarlatzis B,Athanasiadis A

    更新日期:2018-06-01 00:00:00

  • A comparison of live birth rates and perinatal outcomes between cryopreserved oocytes and cryopreserved embryos.

    abstract:PURPOSE:Prior studies suggest that pregnancy outcomes after autologous oocyte cryopreservation are similar to fresh in vitro fertilization (IVF) cycles. It is unknown whether there are differences in pregnancy and perinatal outcomes between cryopreserved oocytes and cryopreserved embryos. METHODS:This is a retrospecti...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-017-0995-2

    authors: Ho JR,Woo I,Louie K,Salem W,Jabara SI,Bendikson KA,Paulson RJ,Chung K

    更新日期:2017-10-01 00:00:00

  • Capacitation IVM improves cumulus function and oocyte quality in minimally stimulated mice.

    abstract:PURPOSE:Oocyte in vitro maturation (IVM) is a patient-friendly reproductive technology but lower success rates than IVF have limited its uptake. Capacitation-IVM (CAPA-IVM) is an innovative new IVM system currently undergoing clinical evaluation. This study aimed to determine temporal effects of the pre-IVM phase of CA...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-019-01610-x

    authors: Zhao Y,Liao X,Krysta AE,Bertoldo MJ,Richani D,Gilchrist RB

    更新日期:2020-01-01 00:00:00

  • Medical research and reproductive medicine in an ethical context: a critical commentary on the paper dealing with uterine lavage published by Munné et al.

    abstract::A recent study published in Human Reproduction claimed that uterine lavage offers a non-surgical, minimally invasive strategy for the recovery of human embryos from fertile women who do not want or need IVF for medical reasons but who desire preimplantation genetic testing (PGT) for embryos. To prove this hypothesis, ...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-020-01954-9

    authors: Murtinger M,Wirleitner B,Hradecký L,Comploj G,Okhowat J,Spitzer D,Stadler J,Haidbauer R,Schuff M,Yildirim S,Soepenberg T,Eibner K,Gagsteiger F

    更新日期:2020-11-01 00:00:00

  • A specific and quick gene expression study in mouse ES cells.

    abstract:PURPOSE:To study gene expression at single embryonic stem cell colony levels with a new RT-PCR protocol. METHODS:Forty-five mouse ES cell colonies were retrieved at the 5th, 10th, 15th, 20th and 25th passages. The pluripotent state was analyzed for OCT-4 and Nanog, and beta-actin as a control for the presence of templ...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-007-9141-x

    authors: Tavares RL,Xu K,Zhang C,de Freitas V

    更新日期:2007-08-01 00:00:00

  • Adjusted mitochondrial DNA quantification in human embryos may not be applicable as a biomarker of implantation potential.

    abstract:OBJECTIVE:To evaluate the feasibility of adjusted mitochondrial DNA quantification in human embryos as a biomarker for implantation potential. DESIGN:Double-blind, observational, prospective analysis of an Asian population in a single university-affiliated in vitro fertilization center. A total of 1617 embryos derived...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-019-01542-6

    authors: Lee YX,Chen CH,Lin SY,Lin YH,Tzeng CR

    更新日期:2019-09-01 00:00:00

  • Cryopreservation of euploid blastocysts obtained after fertilization of in vitro matured ovarian tissue oocytes: a case report.

    abstract::With the increased rate of stable remission after gonadotoxic cancer treatment, new methods of fertility preservation are required in order to provide the best possible care for oncological patients. Here, we report an original case of euploid blastocyst cryopreservation after in vitro maturation of ovarian tissue ooc...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-020-01729-2

    authors: Kirillova A,Kovalskaya E,Brovkina O,Ekimov A,Bunyaeva E,Gordiev M,Mishieva N,Nazarenko T,Abubakirov A,Sukikh G

    更新日期:2020-04-01 00:00:00

  • For whom the egg thaws: insights from an analysis of 10 years of frozen egg thaw data from two UK clinics, 2008-2017.

    abstract:PURPOSE:To better understand the characteristics of patients who returned to thaw their frozen eggs to attempt conception and their outcomes. METHODS:A retrospective analysis of clinical records for all own egg thaw patients in two UK fertility clinics across 10 years, 2008-2017. RESULTS:There were 129 patients who r...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-019-01429-6

    authors: Gürtin ZB,Morgan L,O'Rourke D,Wang J,Ahuja K

    更新日期:2019-06-01 00:00:00

  • Recombinant HCG for triggering ovulation increases the rate of mature oocytes in women treated for ICSI.

    abstract:PURPOSE:To conduct a prospective randomized study in order to investigate the effect of recombinant HCG (rHCG) on oocyte nuclear and cytoplasm maturity compared to urinary HCG (uHCG), for inducing ovulation in women treated with ICSI for male factor infertility. MATERIALS AND METHODS:We compared 89 patients randomly a...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s10815-008-9262-x

    authors: Farrag A,Costantini A,Manna C,Grimaldi G

    更新日期:2008-09-01 00:00:00

  • Should intrauterine human chorionic gonadotropin infusions ever be used prior to embryo transfer?

    abstract:PURPOSE:The aim of this study was to explore the factors that influence the outcome of intrauterine human chorionic gonadotropin (hCG) infusion at the time of embryo transfer (ET), in particular, the effect of hCG infusions on fresh and frozen embryo transfers (FETs) and whether prior recurrent implantation failure (RI...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-017-1049-5

    authors: Volovsky M,Healey M,MacLachlan V,Vollenhoven BJ

    更新日期:2018-02-01 00:00:00

  • Combination of cabergoline and embryo cryopreservation after GnRH agonist triggering prevents OHSS in patients with extremely high estradiol levels--a retrospective study.

    abstract:PURPOSE:Embryo cryopreservation after triggering oocyte maturation with GnRH agonist (GnRHa) in GnRH antagonist protocols has been proposed to prevent ovarian hyperstimulation syndrome (OHSS). However, a small percentage of patients still developed severe OHSS. The purpose of the study was to investigate the efficacy o...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-013-9997-x

    authors: Lin YH,Huang MZ,Hwang JL,Chen HJ,Hsieh BC,Huang LW,Tzeng CR,Seow KM

    更新日期:2013-06-01 00:00:00

  • Combinational approach of retrospective clinical evidence and transcriptomics highlight AMH superiority to FSH, as successful ICSI outcome predictor.

    abstract:OBJECTIVE:Combination of transcriptomic and retrospective clinical data, to assess anti-Mullerian hormone (AMH) functionality at a cumulus cell level and evaluate AMH potential as a suitable marker for IVF outcomes (oocytes retrieved, number of day 3 embryos, gestation outcomes). DESIGN:Raw RNA-sequencing data of cumu...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-020-01802-w

    authors: Kastora SL,Triantafyllidou O,Kolovos G,Kastoras A,Sigalos G,Vlahos N

    更新日期:2020-07-01 00:00:00

  • Human oocyte maturity in vivo determines the outcome of blastocyst development in vitro.

    abstract:PURPOSE:To date, the impact of oocyte maturity at aspiration on the blastocyst formation in vitro has not been fully evaluated. This study was undertaken to assess the influence of oocyte maturity in patients undergoing in vitro fertilization and blastocyst transfer program. METHODS:A total of 1278 oocytes derived fro...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1023/b:jarg.0000013651.37866.0c

    authors: Lin YC,Chang SY,Lan KC,Huang HW,Chang CY,Tsai MY,Kung FT,Huang FJ

    更新日期:2003-12-01 00:00:00

  • Routine laser assisted hatching results in significantly increased clincal pregnancies.

    abstract:PURPOSE:To elucidate the appropriateness of current indications for assisted hatching (AH) in cleavage stage human embryos and to confirm our preliminary findings that only young patients (about 67%) benefit from AH. METHODS:Prior to transfer, 2 of 3 embryos selected for ET were subjected to laser assisted hatching (L...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1023/a:1023665909123

    authors: Ali J,Rahbar S,Burjaq H,Sultan AM,Al Flamerzi M,Shahata MA

    更新日期:2003-05-01 00:00:00

  • Impact of serum estradiol levels on the implantation rate of cleavage stage cryopreserved-thawed embryos transferred in programmed cycles with exogenous hormonal replacement.

    abstract:PURPOSE:To investigate the impact of late follicular phase serum estradiol (E2) levels on implantation and pregnancy outcomes of cleavage stage cryopreserved/thawed embryos transferred in programmed cycles with exogenous hormonal replacement. METHODS:Retrospective cohort analysis of IVF patients with transfer of cryop...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-014-0402-1

    authors: Bocca S,Real EB,Lynch S,Stadtmauer L,Beydoun H,Mayer J,Oehninger S

    更新日期:2015-03-01 00:00:00

  • Is AMH a regulator of follicular atresia?

    abstract::We discuss the hypothesis that AMH is an intraovarian regulator that inhibits follicular atresia within the human ovary. Several indirect lines of evidence derived from clinical and basic science studies in a variety of different patient populations and model systems collectively support this hypothesis. Evidence pres...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章,评审

    doi:10.1007/s10815-014-0328-7

    authors: Seifer DB,Merhi Z

    更新日期:2014-11-01 00:00:00

  • Early timed follicular aspiration prevents severe ovarian hyperstimulation syndrome.

    abstract:PURPOSE:Early timed follicular aspiration (ETFA) of one ovary 10-12 hr after administration of chorionic gonadotropin (hCG) is an attempt to prevent severe ovarian hyperstimulation syndrome (OHSS). After the introduction of early timed follicular aspiration ETFA of one ovary in IVF/ET cycles at high risk for severe OHS...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02070139

    authors: Tomazevic T,Meden-Vrtovec H

    更新日期:1996-04-01 00:00:00

  • Prognostic implication of apoptosis in human luteinized granulosa cells during IVF-ET.

    abstract:PURPOSE:To investigate the prognostic significance of apoptosis in granulosa cells recovered from patients participating in IVF-ET. METHODS:Seventy-three women underwent ovarian hyperstimulation for IVF and embryo transfer. After follicle aspiration, recovered granulosa cells were stained by BCL2 monoclonal antibody w...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1023/a:1015319617598

    authors: Suh CS,Jee BC,Choi YM,Kim JG,Lee JY,Moon SY,Kim SH

    更新日期:2002-05-01 00:00:00

  • Derivation, culture and retinal pigment epithelial differentiation of human embryonic stem cells using human fibroblast feeder cells.

    abstract:PURPOSE:Retinal pigment epithelium cells derived from human embryonic stem cells (ESCs) could be useful for restoring retinal function in age-related macular degeneration. However the use of non-human feeder cells to support the growth of ESCs for clinical applications raises the concern of possible contamination becau...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-012-9802-2

    authors: Zhang YS,Lu ZY,Yu Y,Li XR,Li WB,Wang YN,Geng Y

    更新日期:2012-08-01 00:00:00

  • Mini-swim-up: a new technique of sperm preparation for intracytoplasmic sperm injection.

    abstract:PURPOSE:The male factor is nowadays one of the major problems in the treatment of infertility. New methods of assisted fertilization such as the intracytoplasmic sperm injection (ICSI) show better fertilization and pregnancy rates than classical IVF. METHOD:In this study, we present a new technique of sperm preparatio...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/BF02211143

    authors: Al Hasani S,Küpker W,Baschat AA,Sturm R,Bauer O,Diedrich C,Diedrich K

    更新日期:1995-08-01 00:00:00

  • Social media in the REI clinic: what do patients want?

    abstract:PURPOSE:To elicit patient preferences for social media utilization and content in the infertility clinic. METHODS:This was a cross-sectional survey study conducted in three US fertility practices. Women presenting to the infertility clinic for an initial or return visit were offered an anonymous voluntary social media...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-018-1189-2

    authors: Broughton DE,Schelble A,Cipolla K,Cho M,Franasiak J,Omurtag KR

    更新日期:2018-07-01 00:00:00