Abstract:
AIM:To investigate follicular fluid IGF 1, IGFBP 3 and their effects on IVF outcome in patients using different gonadotropins. MATERIALS AND METHODS:This prospective study was performed among 92 IVF patients who were categorized according to IVF pregnancy outcome. Two groups were formed as Group 1 : pregnant, Group 2: non pregnant. RESULTS:Follicular IGF 1 and IGFBP 3 levels were not different between the two groups. There were negative correlations between follicular IGF 1 and age, gonadotropin dose, embryo numbers in all patients and group 2, but there were no correlations between IGF1 and these parameters in group 1. Although IGFBP 3 levels were not different in patients using rec FSH or HMG, IGF 1 were higher in patients treated by rec FSH compared to patient using HMG. When the groups using rec FSH or HMG were analyzed according to pregnancy rate, there were no differences in IGF 1 levels. CONCLUSION:Follicular IGF 1, IGFBP 3 do not predict clinical IVF outcome regardless of the different gonadotropin preparations.
journal_name
J Assist Reprod Genetjournal_title
Journal of assisted reproduction and geneticsauthors
Genc G,Yilmaz N,Uygur D,Dogan M,Mollamahmutoglu Ldoi
10.1007/s10815-011-9543-7subject
Has Abstractpub_date
2011-05-01 00:00:00pages
405-10issue
5eissn
1058-0468issn
1573-7330journal_volume
28pub_type
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更新日期:2013-11-01 00:00:00
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journal_title:Journal of assisted reproduction and genetics
pub_type: 杂志文章
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更新日期:2008-08-01 00:00:00
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更新日期:2017-02-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2009-09-01 00:00:00
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journal_title:Journal of assisted reproduction and genetics
pub_type: 杂志文章,meta分析
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更新日期:2015-07-01 00:00:00