Abstract：
INTRODUCTION:The causes of acute tubulointerstitial nephritis can be grouped into four broad categories: medications, infections, immunologic diseases, or idiopathic processes. Here we report a 17-year-old female who developed acute kidney injury (AKI) due to granulomatous interstitial nephritis (GIN) associated with influenza A: H1N1 infection. CASE OUTLINE:The illness presented after two weeks of respiratory tract infection, skin rash and hypermenorrhea. On admission the patient was febrile, with bilateral pedal edema, macular skin rash, and auscultatory finding that suggested pneumonia. Laboratory investigations showed normocytic anemia, azotemia, hematuria and proteinuria. Renal ultrasound was normal. Antinuclear antibodies, antineutrophil cytoplasmic antibodies, lupus anticoagulant, antiphospholipid antibodies were negative with normal complement. Urine cultures including analysis for Mycobacterium tuberculosis were negative. The diagnosis of influenza A: H1N1 infection was made by positive serology. A kidney biopsy showed interstitial nephritis with peritubular granulomas. Glomeruli were normal. Staining for immunoglobulins A, M, G, and F was negative. The girl was treated with oseltamivir phosphate (Tamiflu; Genentech, Inc., South San Francisco, CA, USA) for five days, as well as with tapered prednisone after a starting dose of 2 mg/kg. The treatment resulted in a complete remission during two years of follow-up. CONCLUSION:We present a severe but reversible case of GIN and AKI associated with influenza A: H1N1 infection. Although a causal effect cannot be confirmed, this case suggests that influenza A: H1N1 should be considered in the differential diagnosis of GIN manifested with AKI in children.
journal_name
Srp Arh Celok Lekjournal_title
Srpski arhiv za celokupno lekarstvoauthors
Milosevski-Lomić G,Marković-Lipkovski J,Kostić M,Dusan Paripović,Spasojević-Dimitrijeva B,Peco-Antić Asubject
Has Abstractpub_date
2016-03-01 00:00:00pages
215-8issue
3-4eissn
0370-8179issn
2406-0895journal_volume
144pub_type
杂志文章abstract：INTRODUCTION:Theory of multiple intelligences (MI) is considered an innovation in learning the English language because it helps students develop all eight intelligences that, on the other hand, represent ways people understand the world around them, solve problems and learn. They are: verbal/linguistic, logical/mathem...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
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journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：INTRODUCTION:Root coverage supported with complete regeneration of lost periodontal tissues represents the ultimate goal of gingival recession treatment. OBJECTIVE:This study was designed to evaluate clinical effectiveness of platelet rich plasma gel (PRP) with connective tissue graft (CTG) in the treatment of gingiva...
journal_title：Srpski arhiv za celokupno lekarstvo
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doi：10.2298/sarh0804095a
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abstract：:Search and disclosure of most adequate diagnostic criteria and prognostic indicators of disease represents one of the most difficult tasks in the understanding of any disease, which creates the way toward a more successful treatment and longer survival. The recent advances in research techniques that have helped refin...
journal_title：Srpski arhiv za celokupno lekarstvo
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journal_title：Srpski arhiv za celokupno lekarstvo
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doi：
更新日期：2013-07-01 00:00:00
abstract：:Primary hyperparathyroidism (HPT) is rarely diagnosed in our country and when found, it is in the very late phase. Skeletal and renal forms of the disease are predominating, as it was in the developed couuntries thirty or forty years ago. Among 100 patients operated for HPT from 1980 to 1993, skeletal changes dominate...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：INTRODUCTION:The development of effective medications makes pharmacological therapy of BPH the dominant mode of treatment today. It improves urinary symptoms and prevents disease progression while producing side effects on male sexual function. OBJECTIVE:The aim of the study is to present the effects of BPH pharmacolo...
journal_title：Srpski arhiv za celokupno lekarstvo
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journal_title：Srpski arhiv za celokupno lekarstvo
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doi：10.2298/sarh1106322c
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journal_title：Srpski arhiv za celokupno lekarstvo
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doi：10.2298/sarh1108491s
更新日期：2011-07-01 00:00:00
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journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1002079v
更新日期：2010-01-01 00:00:00
abstract：:One of the most frequent causes of deterioration of chronic obstructive lung diseases is the infection. The existence of microorganisms resistant to antibiotics is becoming an increasingly serious therapeutical problem. Kinolones have a wider spectrum of action than the majority of other antibiotics, with strong effec...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：:We have treated 55 children with accommodative esotropia and high AC/A ratio with progressive addition lenses, measured by heterophoria method. All of them wear full hyperopic refraction for distance and addition of +1.00 to 3.5 spheres for near vision. The minimal add that allowed the maximal reduction in the near de...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
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journal_title：Srpski arhiv za celokupno lekarstvo
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更新日期：2009-01-01 00:00:00
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journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
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更新日期：2002-11-01 00:00:00
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journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0308285p
更新日期：2003-07-01 00:00:00
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journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 临床试验,杂志文章,多中心研究
doi：
更新日期：2015-01-01 00:00:00
abstract：:A patient, aged 28, was admitted to the Department of Urology of the Military Medical Academy in Belgrade, for the operation of the right adrenal gland tumour. The adrenal gland tumour was first diagnosed as an inactive hormonal tumour. Intraoperatively it was found in retroperitoneal area, over the right adrenal glan...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1991-09-01 00:00:00
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journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：
更新日期：1995-07-01 00:00:00
abstract：INTRODUCTION:The most common fracture involving the wrist is a fracture of the scaphoid bone [1], and only 5% to 10% of these fractures proceed to nonunion. Although not symptomatic initially, most (if not all) nonunions later produce a painful wrist with impaired function, clinically significant loss of motion, increa...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：2001-05-01 00:00:00
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journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
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journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1502093n
更新日期：2015-01-01 00:00:00
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journal_title：Srpski arhiv za celokupno lekarstvo
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更新日期：2010-07-01 00:00:00
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journal_title：Srpski arhiv za celokupno lekarstvo
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更新日期：2009-11-01 00:00:00
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journal_title：Srpski arhiv za celokupno lekarstvo
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journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：
更新日期：1994-05-01 00:00:00
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journal_title：Srpski arhiv za celokupno lekarstvo
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doi：10.2298/sarh0908430a
更新日期：2009-07-01 00:00:00
abstract：:Inflammatory response in tissue results from a complex network of interactions between inflammatory cells (mast cells, eosinophils, basophils, macrophages) and resident cells belonging to the lung structure (like endothelial cells, fibroblasts, epithelial cells). Among structural cells, endothelial cells play a critic...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：
更新日期：1998-03-01 00:00:00
abstract：:The purpose of this investigation was to evaluate epidemiologic features of Ewing sarcoma in children treated in the Institute for Orthopedic Surgery "Banjica: as well as to establish relation of these features to clinical findings. Study involved 78 patients treated over 20-year period (1980-2000). Analysis included ...
journal_title：Srpski arhiv za celokupno lekarstvo
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doi：10.2298/sarh0608310s
更新日期：2006-07-01 00:00:00
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journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1994-11-01 00:00:00
abstract：INTRODUCTION:The prevalence of obesity is rising to epidemic proportions at the alarming rate in both developed and underdeveloped countries around the world. Current prevalence data from individual national studies suggest that the obesity prevalence in the European countries ranges from 10% to 20% for men, and 10% to...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0702061g
更新日期：2007-01-01 00:00:00
