Efficacy of lenvatinib in treating thyroid cancer.

abstract：:There has been a significant increase in the number of cases of skin cancer diagnosed in the US in the past few years. Thus, it seems appropriate to review the available compounds that might be used in the chemoprevention of these lesions. This review focuses on the retinoids and details their results in clinical tria...

journal_title：Expert opinion on pharmacotherapy

authors： Niles RM

更新日期：2002-03-01 00:00:00

abstract：INTRODUCTION:Colorectal cancer (CRC) is the third most common cancer in the western world and also in Japan. The key factors in curing CRC are early detection, surgery and adequate adjuvant chemotherapy if needed. AREAS COVERED:Based on the results of following pivotal adjuvant trials, FOLFOX or XELOX are considered s...

journal_title：Expert opinion on pharmacotherapy

authors： Tsuji Y,Sugihara K

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:Clostridium difficile has become the most important healthcare-associated infection worldwide within the past decade. This is in part due to the emergence of a highly virulent epidemic strain of C. difficile as well as the relative ineffectiveness of current therapies at producing a sustained response. Fid...

journal_title：Expert opinion on pharmacotherapy

authors： Hostler CJ,Chen LF

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Moderate hypertriglyceridemia is fairly common, and elevated triglycerides are a risk factor for coronary heart disease. The omega-3 fatty acids EPA and DHA have been shown to lower triglycerides in many clinical studies. Prescription omega-3 fatty acid concentrates (P-OM3) are indicated for use in people wi...

journal_title：Expert opinion on pharmacotherapy

authors： Skulas-Ray AC,West SG,Davidson MH,Kris-Etherton PM

更新日期：2008-05-01 00:00:00

abstract：:The development of effective treatments for opioid dependence is of great importance given the devastating consequences of the disease. Pharmacotherapies for opioid addiction include opioid agonists, partial agonists, opioid antagonists, and alpha-2-adrenergic agonists, which are targeted toward either detoxification ...

journal_title：Expert opinion on pharmacotherapy

authors： Stotts AL,Dodrill CL,Kosten TR

更新日期：2009-08-01 00:00:00

abstract：INTRODUCTION:Despite the availability of many antihypreglycemic agents, many patients with type 2 diabetes (T2DM) fail to achieve the glycemic treatment goal, primarily due to progressive beta-cell dysfunction, and increased risk of hypoglycemia. AREAS COVERED:The aim of the present article is to review the efficacy a...

journal_title：Expert opinion on pharmacotherapy

authors： Abdul-Ghani MA,DeFronzo RA

更新日期：2013-08-01 00:00:00

abstract：IMPORTANCE OF THE FIELD:Prostate cancer is a common cancer and the role of adjuvant medical therapy continues to be investigated. An understanding of the use of adjuvant medical therapy is essential for the appropriate care of prostate cancer patients, especially for those with locally advanced or high-risk disease. A...

journal_title：Expert opinion on pharmacotherapy

authors： Sumey C,Flaig TW

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Hypertension is highly prevalent in patients with end-stage kidney disease on hemodialysis and is often not well controlled. Blood pressure (BP) levels before and after hemodialysis have a U-shaped relationship with cardiovascular and all-cause mortality. Although antihypertensive drugs are recommended for...

journal_title：Expert opinion on pharmacotherapy

authors： Maruyama T,Takashima H,Abe M

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:Much research has gone into developing medications that can be used to alleviate endometriosis-associated symptoms. In addition to already established medications, a new GnRH antagonist, elagolix, is in development. The novelty of this drug compared to other GnRH antagonists, is its nonpeptide structure, a...

journal_title：Expert opinion on pharmacotherapy

authors： Perricos A,Wenzl R

更新日期：2017-09-01 00:00:00

abstract：:New approved options with opioids in the postoperative setting may include new ways of administration, new combinations with other drugs and new opioid drugs. Newly approved devices for administration include sublingual sufentanil dispenser and transdermal iontophoretic fentanyl, with the purpose of almost mimicking t...

journal_title：Expert opinion on pharmacotherapy

authors： Raeder J

更新日期：2014-03-01 00:00:00

abstract：:Introduction: Triptorelin is a luteinizing hormone-releasing hormone analog (LH-RHa) inducing ovarian function suppression (OFS). It is approved by FDA and EMA in association with tamoxifen or aromatase inhibitor (AI) and with fulvestrant and palbociclib in premenopausal women with hormone receptor (HR)-positive breas...

journal_title：Expert opinion on pharmacotherapy

authors： Ferraro E,Trapani D,Marrucci E,Curigliano G

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:Heart failure (HF) treatment attracts a share of intensive research because of its poor HF prognosis. In the past decades, the prognosis of HF has improved considerably, mainly as a consequence of the progress that has been made in the pharmacological management of HF. AREAS COVERED:This article reviews t...

journal_title：Expert opinion on pharmacotherapy

authors： Kaldara E,Sanoudou D,Adamopoulos S,Nanas JN

更新日期：2015-01-01 00:00:00

abstract：:The aim of this review is to provide a rationale for evaluating thiazolidinediones (TZDs) as putative treatments for cognitive deficits in individuals with mood disorders. A MedLine search of all English-language articles published between January 1966 and August 2006 was conducted. The search terms were: the non-prop...

journal_title：Expert opinion on pharmacotherapy

authors： McIntyre RS,Soczynska JK,Woldeyohannes HO,Lewis GF,Leiter LA,MacQueen GM,Miranda A,Fulgosi D,Konarski JZ,Kennedy SH

更新日期：2007-08-01 00:00:00

abstract：:Antiplatelet therapy is the cornerstone of treatment for patients who present with acute coronary syndrome (ACS) or undergo percutaneous coronary intervention (PCI). Clopidogrel, in combination with aspirin, is associated with improvement in long-term clinical outcomes in these patients and is currently the antiplatel...

journal_title：Expert opinion on pharmacotherapy

authors： Angiolillo DJ,Suryadevara S,Capranzano P,Bass TA

更新日期：2008-11-01 00:00:00

abstract：:The rising incidence of invasive fungal infections and the emergence of broader fungal resistance have led to the need for novel antifungal agents. Posaconazole is a new member of the triazole class of antifungals. It is available as an oral suspension and has a favorable toxicity profile, has demonstrated clinical ef...

journal_title：Expert opinion on pharmacotherapy

authors： Kwon DS,Mylonakis E

更新日期：2007-06-01 00:00:00

abstract：INTRODUCTION:As type 2 diabetes mellitus (T2DM) advances, patients receiving basal insulin will eventually require another agent on top of their current regimen in order to achieve glycemic control. One such agent that can be administered in combination with basal insulin is the glucagon-like peptide-1 receptor agonist...

journal_title：Expert opinion on pharmacotherapy

authors： Forst T

更新日期：2016-08-01 00:00:00

abstract：:Alcoholism is the third leading cause of preventable mortality and morbidity in the US. In the COMBINE (Combined Pharmacotherapies and Behavioural Interventions) study, the co-primary end points were the percentage of days abstinent and the time to first heavy drinking day after 16 weeks, and 1 year. The biggest diffe...

journal_title：Expert opinion on pharmacotherapy

authors： Doggrell SA

更新日期：2006-10-01 00:00:00

abstract：INTRODUCTION:Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune condition traditionally viewed as a severe destructive disease affecting physical health and global wellbeing. The treatment strategies for RA have changed in the last decades from mainly symptomatic towards a more vigorous and targeted approac...

journal_title：Expert opinion on pharmacotherapy

authors： De Cock D,Van der Elst K,Meyfroidt S,Verschueren P,Westhovens R

更新日期：2015-01-01 00:00:00

abstract：:Despite the revolutionary introduction of antibiotic therapy in the post-World War II era, primary care physicians continue to struggle with the issue of optimal treatment strategies for bacterial infection and the growing problem of antimicrobial resistance. The aggressive use of potent agents as first-line therapy m...

journal_title：Expert opinion on pharmacotherapy

authors： Nicolau DP

更新日期：2004-02-01 00:00:00

abstract：INTRODUCTION:Bradykinin-mediated angioedema is characterized by subcutaneous and/or submucosal edema formation without wheals and pruritus. It is linked to bradykinin-enhanced vascular permeability and, therefore, it does not respond to conventional measures, but requires specific therapy. AREAS COVERED:This summary b...

journal_title：Expert opinion on pharmacotherapy

authors： Farkas H

更新日期：2013-04-01 00:00:00

abstract：INTRODUCTION:Combination of glibenclamide (glyburide in the U.S.) and metformin hydrochloride simultaneously addresses two different but complimentary mechanisms to improve glycemic control in type 2 diabetes. AREAS COVERED:The pharmacokinetics, efficacy, and side effect profile of the oral combination of glibenclamid...

journal_title：Expert opinion on pharmacotherapy

authors： Lamos EM,Stein SA,Davis SN

更新日期：2012-12-01 00:00:00

abstract：IMPORTANCE OF THE FIELD:Diabetes mellitus is the most common endocrine disease in childhood. The global incidence of diabetes emphasizes the health, social and financial magnitude of this disease and the importance of optimizing disease management and prevention. AREAS COVERED IN THIS REVIEW:This article reviews the t...

journal_title：Expert opinion on pharmacotherapy

authors： Verrotti A,Chiuri RM,Blasetti A,Mohn A,Chiarelli F

更新日期：2010-10-01 00:00:00

abstract：INTRODUCTION:Irritability (including tantrums, aggression and moodiness) is often associated with autistic disorder. Children with autism are frequently prescribed atypical antipsychotic medications for these behaviors. Although multiple agents have been found to be effective, the safety and tolerability of each antips...

journal_title：Expert opinion on pharmacotherapy

authors： Farmer CA,Aman MG

更新日期：2011-03-01 00:00:00

abstract：INTRODUCTION:Antifungal resistance is an emerging problem that increases morbidity and mortality in immunosuppressed pediatric patients, who suffer from invasive fungal diseases. Optimal pharmacological management is critical for the successful treatment of invasive fungal infections by resistant strains. AREAS COVERE...

journal_title：Expert opinion on pharmacotherapy

authors： Stergiopoulou T,Walsh TJ

更新日期：2015-02-01 00:00:00

abstract：:Ribavirin is a very broad-spectrum virustatic antiviral agent, first synthesised in 1972. It is characterised by low toxicity apart from reversible anaemia, usually mild. Its multiple mechanisms of action mean that viral resistance rarely develops. It can be administered orally, intravenously, or via a nebuliser. It h...

journal_title：Expert opinion on pharmacotherapy

authors： Snell NJ

更新日期：2001-08-01 00:00:00

abstract：:Genomic variations influencing response to pharmacotherapy of pain are under investigation. Candidate genes such as (opioid)-receptors, transporters and other molecules important for pharmacotherapy are discussed. Drug metabolising enzymes represent a further major target of ongoing research in order to identify assoc...

journal_title：Expert opinion on pharmacotherapy

authors： Stamer UM,Stüber F

更新日期：2007-10-01 00:00:00

abstract：:Seborrhoeic dermatitis (SD) is a recurrent, chronic inflammation of the skin that occurs on sebum rich areas such as the face, scalp and chest, characterised by red scaly lesions. The are many studies indicating that Malassezia yeasts play an important role in the aetiology of this condition, most of the evidence for ...

journal_title：Expert opinion on pharmacotherapy

authors： Gupta AK,Kogan N

更新日期：2004-08-01 00:00:00

abstract：INTRODUCTION:Over the past decade, treatment options for men with metastatic castration-resistant prostate cancer (CRPC) have expanded with the addition of abiraterone acetate (AA), enzalutamide, sipuleucel-T, radium-223, docetaxel and cabazitaxel. The optimal sequencing of therapies in the context of efficacy and know...

journal_title：Expert opinion on pharmacotherapy

authors： Zhang T,Zhu J,George DJ,Armstrong AJ

更新日期：2015-03-01 00:00:00

abstract：IMPORTANCE OF THE FIELD:The emergence of fixed-combination drugs for the treatment of glaucoma has, to some extent, changed the medical management of glaucoma. The potential benefits of these drugs include a reduction in the total number of drops and preservatives instilled per day and improved patient comfort factors,...

journal_title：Expert opinion on pharmacotherapy

authors： Razeghinejad MR,Sawchyn AK,Katz LJ

更新日期：2010-04-01 00:00:00

abstract：:The administration of oral aspirin within 48 h and tissue plasminogen activator within 3 h of ischaemic stroke onset remain the only treatments that have been shown to have clinical benefit. There has been much excitement about neuroprotection over the last two decades, as it may minimise the harmful effects of ischae...

journal_title：Expert opinion on pharmacotherapy

authors： Ly JV,Zavala JA,Donnan GA

更新日期：2006-08-01 00:00:00