Incidence of tramadol shopping behavior in a retrospective cohort of chronic non-cancer pain patients in France.

Abstract:

PURPOSE:Opioid analgesic use in chronic non-cancer pain (CNCP) is increasingly prevalent, but the benefits and risks are inadequately understood. In France, tramadol is one of the most used prescription opioids, but studies on its misuse liability in CNCP are still lacking. The aim was to assess the incidence of tramadol shopping behavior in CNCP patients and to identify the associated risk factors. METHODS:A retrospective cohort of CNCP patients aged 18 years and older treated by tramadol for at least six consecutive months between 2005 and 2013 from a sample of the French Health Insurance database was established. Doctor shopping was defined as at least 1 day of overlapping prescriptions written by two or more different prescribers and filled in at least three different pharmacies. RESULTS:A total of 3505 CNCP patients were included with a majority of women (66.4%) and a mean age of 66.4 ± 14.7 years. The median tramadol treatment duration was 260 [interquartile range: 211-356] days. The 1-year incidence rate of tramadol shopping behavior was 1.0% [95%CI: 0.7-1.5]. On multivariate analysis, risk factors associated with tramadol shopping behavior were age (hazard ratio [HR] = 7.4 [95%CI: 2.8-19.7] for age <40, HR = 2.8 [95%CI: 1.0-7.7] for 40 ≤ age < 50, versus age ≥50), low-income status (HR = 8.5 [95%CI: 3.6-20.5]), and prior use of strong opioids (HR = 5.7 [95%CI: 1.9-17.0]). CONCLUSION:Tramadol shopping behavior incidence appears low in CNCP patients but may represent a public health concern given the widespread use of tramadol. Education and best monitoring of high-risk patients are needed to reduce doctor shopping. Copyright © 2016 John Wiley & Sons, Ltd.

authors

Chenaf C,Kabore JL,Delorme J,Pereira B,Mulliez A,Roche L,Eschalier A,Delage N,Authier N

doi

10.1002/pds.4056

subject

Has Abstract

pub_date

2016-09-01 00:00:00

pages

1088-98

issue

9

eissn

1053-8569

issn

1099-1557

journal_volume

25

pub_type

杂志文章
  • High use of health services in patients with suboptimal asthma drug regimens: a population-based assessment in British Columbia, Canada.

    abstract:BACKGROUND:Despite numerous clinical guidelines on asthma management, patients often receive suboptimal drug therapy. This study identified patients who received suboptimal regimens according to the National Heart, Lung and Blood Institute (NHLBI) Guidelines for the Diagnosis and Management of Asthma in a complete popu...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.3444

    authors: Zhang T,Smith MA,Camp PG,Carleton BC

    更新日期:2013-07-01 00:00:00

  • Long-term use of antihypertensive drugs and risk of cancer.

    abstract:PURPOSE:Determine the relative risk of cancer users of commonly prescribed antihypertensive drugs with a focus on documenting risk in long-term users (>7.5 years). METHODS:We conducted a nested case-control study using the Saskatchewan Health databases. Cancer risks in users of beta-blockers, calcium channel blockers ...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.1656

    authors: Assimes TL,Elstein E,Langleben A,Suissa S

    更新日期:2008-11-01 00:00:00

  • Validation of low-dose aspirin prescription data in The Health Improvement Network: how much misclassification due to over-the-counter use?

    abstract:PURPOSE:We aimed to quantify the extent of over-the-counter (OTC) low-dose aspirin use among patients in The Health Improvement Network (THIN) in the UK. METHODS:In September 2013, a random sample of low-dose aspirin users (75 past users and 75 never users) was identified based on prescriptions recorded in THIN. Prima...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.3926

    authors: Cea Soriano L,Soriano-Gabarró M,García Rodríguez LA

    更新日期:2016-04-01 00:00:00

  • Assessing the accuracy of opioid overdose and poisoning codes in diagnostic information from electronic health records, claims data, and death records.

    abstract:PURPOSE:The purpose of this study is to assess positive predictive value (PPV), relative to medical chart review, of International Classification of Diseases (ICD)-9/10 diagnostic codes for identifying opioid overdoses and poisonings. METHODS:Data were obtained from Kaiser Permanente Northwest and Northern California....

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.4157

    authors: Green CA,Perrin NA,Janoff SL,Campbell CI,Chilcoat HD,Coplan PM

    更新日期:2017-05-01 00:00:00

  • A large simple clinical trial prototype for assessment of OTC drug effects using patient-reported data.

    abstract:PURPOSE:Innovative methods are needed to assess risks related to treatment for common medical conditions, where therapy is usually patient-directed or over-the-counter (OTC), and where tolerability, i.e. patient experienced events, may affect patterns of use. A large-scale, blinded, randomised trial was conducted to co...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1002/pds.1083

    authors: Van Ganse E,Jones JK,Moore N,Parc JM,Wall R,Schneid H

    更新日期:2005-04-01 00:00:00

  • Validation of claims-based algorithms for identification of high-grade cervical dysplasia and cervical cancer.

    abstract:BACKGROUND:High-grade cervical dysplasia or cervical intraepithelial neoplasia grade 2 or worse has been widely used as a surrogate endpoint in cervical cancer screening or prevention trials. METHODS:To identify high-grade cervical dysplasia and cervical cancer, we developed claims-based algorithms that incorporated a...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.3520

    authors: Kim SC,Gillet VG,Feldman S,Lii H,Toh S,Brown JS,Katz JN,Solomon DH,Schneeweiss S

    更新日期:2013-11-01 00:00:00

  • Exposure to reactive intermediate-inducing drugs during pregnancy and the incident use of psychotropic medications among children.

    abstract:PURPOSE:Our study aimed to investigate the association between prenatal exposure to reactive intermediate (RI)-inducing drugs and the initiation of psychotropic medications among children. METHODS:We designed a cohort study using a pharmacy prescription database. Pregnant women were considered exposed when they receiv...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.4161

    authors: Tran YH,Groen H,Bergman JE,Hak E,Wilffert B

    更新日期:2017-03-01 00:00:00

  • Global benefit-risk analysis of adjunctive aripiprazole in the treatment of patients with major depressive disorder.

    abstract:OBJECTIVE:This study quantified the overall merit of adjunctive aripiprazole in major depressive disorder (MDD). METHODS:Global benefit-risk (GBR) analysis quantified the benefit and risk differences between adjunctive aripiprazole and antidepressant (ADT) monotherapy. Three hundred and fifty six patients receiving AD...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.1805

    authors: Wisniewski SR,Chen CC,Kim E,Kan HJ,Guo Z,Carlson BX,Tran QV,Pikalov A

    更新日期:2009-10-01 00:00:00

  • Herbal products use during pregnancy: prevalence and predictors.

    abstract:PURPOSES:(1) Measure the prevalence of herbal product (HP) use, alone, and concomitantly with prescribed medications during pregnancy, (2) identify the most frequently consumed HP during gestation and (3) determine predictors of HP use at the beginning of pregnancy, and during the third trimester. METHODS:A questionna...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章,评审

    doi:10.1002/pds.1731

    authors: Moussally K,Oraichi D,Bérard A

    更新日期:2009-06-01 00:00:00

  • Asthma drug use and the development of Churg-Strauss syndrome (CSS).

    abstract:PURPOSE:Case reports suggest that leukotriene modifier use may be associated with the onset of Churg-Strauss syndrome (CSS). Using pooled data from two nested case-control studies, we examined the association between asthma drug use and the development of CSS. METHODS:The study was performed in three US managed care o...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.1353

    authors: Harrold LR,Patterson MK,Andrade SE,Dube T,Go AS,Buist AS,Chan KA,Weller PF,Wechsler ME,Yood RA,Davis KJ,Platt R,Walker AM

    更新日期:2007-06-01 00:00:00

  • Comparison of the ability of double-robust estimators to correct bias in propensity score matching analysis. A Monte Carlo simulation study.

    abstract:OBJECTIVE:As covariates are not always adequately balanced after propensity score matching and double- adjustment can be used to remove residual confounding, we compared the performance of several double-robust estimators in different scenarios. METHODS:We conducted a series of Monte Carlo simulations on virtual obser...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.4325

    authors: Nguyen TL,Collins GS,Spence J,Devereaux PJ,Daurès JP,Landais P,Le Manach Y

    更新日期:2017-12-01 00:00:00

  • Media attention and the influence on the reporting odds ratio in disproportionality analysis: an example of patient reporting of statins.

    abstract:AIM:To study the influence of media attention about statins and ADRs on the level of disproportionality, expressed as the reporting odds ratio (ROR) for statins in the Lareb database, based on patients' reports. METHODS:Patient reports about statins, before and after the broadcast of a consumer programme about statins...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.1865

    authors: van Hunsel F,van Puijenbroek E,de Jong-van den Berg L,van Grootheest K

    更新日期:2010-01-01 00:00:00

  • Antidepressant medication use and breast cancer risk.

    abstract:PURPOSE:Most epidemiologic studies have detected no association between prior use of antidepressant medications and breast cancer risk. Despite the uniform conclusion, there is a continuous rise in the proportion of women using antidepressants, lending support to further monitoring of disease effects. METHODS:We condu...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.1719

    authors: Wernli KJ,Hampton JM,Trentham-Dietz A,Newcomb PA

    更新日期:2009-04-01 00:00:00

  • Increase in the duration of antidepressant treatment from 1994 to 2003: a nationwide population-based study from Finland.

    abstract:OBJECTIVE:We examined the length and continuity of antidepressant treatment and factors associated with long-term of treatment among adults. METHODS:Nationwide data from all reimbursed antidepressant prescriptions in 1994-2003 were linked with patients' data retrieved from Statistics Finland and the Finnish Hospital D...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.2017

    authors: Sihvo S,Wahlbeck K,McCallum A,Sevon T,Arffman M,Haukka J,Keskimäki I,Hemminki E

    更新日期:2010-11-01 00:00:00

  • Moderate alcohol consumption and adverse drug reactions among older adults.

    abstract:PURPOSE:To assess the effect of moderate alcohol consumption on Adverse Drug Reactions (ADRs) among older adults admitted to acute care hospitals and to examine the consistency of this effect across gender and age groups. METHODS:We used the GIFA (Italian Group of Pharmacoepidemiology in the Elderly) database, which i...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.721

    authors: Onder G,Landi F,Della Vedova C,Atkinson H,Pedone C,Cesari M,Bernabei R,Gambassi G,GIFA Study.

    更新日期:2002-07-01 00:00:00

  • Weaknesses of goodness-of-fit tests for evaluating propensity score models: the case of the omitted confounder.

    abstract:PURPOSE:Propensity scores are used in observational studies to adjust for confounding, although they do not provide control for confounders omitted from the propensity score model. We sought to determine if tests used to evaluate logistic model fit and discrimination would be helpful in detecting the omission of an imp...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.986

    authors: Weitzen S,Lapane KL,Toledano AY,Hume AL,Mor V

    更新日期:2005-04-01 00:00:00

  • Validity and completeness of colorectal cancer diagnoses in a primary care database in the United Kingdom.

    abstract:PURPOSE:To validate the recorded diagnoses of colorectal cancer (CRC) and identify false negatives in The Health Improvement Network (THIN) primary care database. METHODS:We conducted a validation study of incident CRC cases in THIN among patients aged 40-89 years from 2000-2011. CRC Read code entries (N = 3805) were ...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.3877

    authors: Cea Soriano L,Soriano-Gabarró M,García Rodríguez LA

    更新日期:2016-04-01 00:00:00

  • Mortality in schizophrenia.

    abstract::Schizophrenia is a life-threatening disease associated with mortality rates that are two to three times higher than those expected/observed in the general population. It is associated with high levels of suicide, particularly in young male patients soon after diagnosis. Delays in treating schizophrenia could contribut...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章,评审

    doi:10.1002/pds.1496

    authors: Auquier P,Lançon C,Rouillon F,Lader M

    更新日期:2007-12-01 00:00:00

  • Use of albumin in three French university hospitals: is prescription monitoring still useful in 2004?

    abstract:PURPOSE:Use of albumin (indications and quantities involved) has not been assessed in France since major changes occurred after the publication of Cochrane group meta-analysis. The objectives of this study were to measure the repartition of albumin indications in three French university hospitals in 2004 and to assess ...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.1328

    authors: Pradel V,Tardieu S,Micallef J,Signoret A,Villano P,Gauthier L,Vanelle P,Blin O,Albumin Study Group.

    更新日期:2007-01-01 00:00:00

  • Psychosocial factors at the workplace--do they affect substance use? Evidence from the Tyrolean workplace study.

    abstract:BACKGROUND:To determine the prevalence of drug consumption and the impact of workplace demands and burdens for substance use, we conducted a survey in a representative sample of Tyrolean employees. METHODS:This analysis was restricted to the 700 respondents (395 male, 305 female; age 18-60 years) in the year 2001 by t...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.955

    authors: Traweger C,Kinzl JF,Traweger-Ravanelli B,Fiala M

    更新日期:2004-06-01 00:00:00

  • Prescription of antiepileptic medicines including valproate in pregnant women: A study in three European countries.

    abstract:PURPOSE:To study patterns of antiepileptic drugs (AED) prescribing, particularly valproate, during pregnancy over a 10-year period in the UK, Italy, and France. METHODS:Data on pregnancies conceived after 1 January 2007 with outcomes before 31 December 2016 were extracted from four European electronic health care data...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.4897

    authors: Hurault-Delarue C,Morris JK,Charlton R,Gini R,Loane M,Pierini A,Puccini A,Neville A,Snowball J,Damase-Michel C,EUROmediSAFE consortium.

    更新日期:2019-11-01 00:00:00

  • Development of pharmacovigilance system in Ukraine: first results.

    abstract::The article is devoted to the establishment and development of the National Pharmacovigilance system in Ukraine. A drug safety centre of Ukraine started to form a pharmacovigilance system in 1996. It has been operating on a regular basis since 2000 and now provides the regulatory services that include data collection ...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.886

    authors: Stefanov O,Sharayeva M,Jajtchenja V

    更新日期:2004-03-01 00:00:00

  • Base de Datos para la Investigación Farmacoepidemiológica en Atención Primaria (BIFAP): A data resource for pharmacoepidemiology in Spain.

    abstract:PURPOSE:Base de Datos para la Investigación Farmacoepidemiológica en Atención Primaria (BIFAP) is a population based database administered by the AEMPS (Spanish Agency for Medicines) of longitudinal electronic medical records (EMR) of patients attended in primary care. Its main purpose is to serve as source of informat...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.5006

    authors: Maciá-Martínez MA,Gil M,Huerta C,Martín-Merino E,Álvarez A,Bryant V,Montero D,BIFAP Team.

    更新日期:2020-10-01 00:00:00

  • Pre-existing cardiovascular conditions and pharmacological treatment of adult ADHD.

    abstract:BACKGROUND:Stimulants and atomoxetine should generally not be used or used only with caution in adults with pre-existing cardiovascular conditions. The extent to which pre-existing cardiovascular conditions influence initiation of these ADHD medications in adults is not known. METHODS:We performed a retrospective coho...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.1931

    authors: Gerhard T,Winterstein AG,Olfson M,Huang C,Saidi A,Crystal S

    更新日期:2010-05-01 00:00:00

  • Retraction. "Epidemiological evaluation of intraoperative antibiosis as a protective agent against endophthalmitis after cataract surgery" by F. Krummenauer, S. Kurz and H.B. Dick.

    abstract::The following article from Pharmacoepidemiology and Drug Safety, “Epidemiological evaluation of intraoperative antibiosis as a protective agent against endophthalmitis after cataract surgery” by F. Krummenauer, S. Kurz and H.B. Dick, published online on July 11 2006 inWiley Online Library (wileyonlinelibrary.com), has...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 撤回出版物

    doi:

    authors:

    更新日期:2013-02-01 00:00:00

  • vigiRank for statistical signal detection in pharmacovigilance: First results from prospective real-world use.

    abstract:PURPOSE:vigiRank is a data-driven predictive model for emerging safety signals. In addition to disproportionate reporting patterns, it also accounts for the completeness, recency, and geographic spread of individual case reporting, as well as the availability of case narratives. Previous retrospective analysis suggeste...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.4247

    authors: Caster O,Sandberg L,Bergvall T,Watson S,Norén GN

    更新日期:2017-08-01 00:00:00

  • Revitalizing the General Practice Research Database: plans, challenges, and opportunities.

    abstract::The General Practice Research Database (GPRD) is the world's largest computerized database of anonymized longitudinal patient records from general practice and is a unique public health research tool. Several issues have threatened the viability of the database in recent years; in April 1999 responsibility for its man...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.608

    authors: Wood L,Coulson R

    更新日期:2001-08-01 00:00:00

  • Epidemiology of multimorbidity in Iran: An investigation of a large pharmacy claims database.

    abstract:PURPOSE:Multimorbidity (MM) (presence of more than one chronic condition within a same patient) imposes a heavy burden on patients and health care systems. In contrast to high-income countries, the epidemiology of this phenomenon is unclear in low- and middle-income countries, particularly among Iranian population. ME...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.4925

    authors: Ebrahimoghli R,Janati A,Sadeghi-Bazargani H,Hamishehkar H,Ghaffari S,Sanaat Z,Farahbakhsh M,Farhoudi M,Khalili-Azimi A

    更新日期:2020-01-01 00:00:00

  • Pattern of adverse drug reactions to anti-epileptic drugs: a cross-sectional one-year survey at a tertiary care hospital.

    abstract:PURPOSE:To investigate pattern and extent of adverse drug reactions (ADRs) associated with AEDs and to identify safer options for treatment of epilepsy. METHOD:Study was a retrospective, cross-sectional survey. Data from patients with epilepsy at the out-patient and in-patient of Neurology Department was collected in ...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.1540

    authors: S RB,Narayan SS,Sharma GR,Rodrigues RJ,Kulkarni C

    更新日期:2008-08-01 00:00:00

  • Adverse drug events among children presenting to a hospital emergency department in Newfoundland and Labrador, Canada.

    abstract:OBJECTIVES:The aim of this study was to examine epidemiologic characteristics of Adverse Drug Events (ADEs) among children and adolescents presenting to an Emergency Department (ED) in Newfoundland and Labrador (NL), Canada. MATERIALS AND METHODS:This study was conducted in three phases and included an ED chart review...

    journal_title:Pharmacoepidemiology and drug safety

    pub_type: 杂志文章

    doi:10.1002/pds.1900

    authors: Sikdar KC,Alaghehbandan R,Macdonald D,Barrett B,Collins KD,Gadag V

    更新日期:2010-02-01 00:00:00