Intracytoplasmic morphologically selected sperm injection and congenital birth defects: a retrospective cohort study.

abstract：BACKGROUND:The transcription factor DMRTB1 plays a pivotal role in coordinating the transition between mitosis and meiosis in murine germ cells. No reliable data are available for human testis. OBJECTIVES:The present study aims to examine the testicular expression pattern of DMRTB1 in men showing normal and impaired s...

journal_title：Andrology

authors： Hilbold E,Bergmann M,Fietz D,Kliesch S,Weidner W,Langeheine M,Rode K,Brehm R

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:The existing classifications of varicocoeles have poor predictive value regarding the effects of surgery on sperm count. OBJECTIVE:To develop a new grading system for varicocoeles, useful as an indication for surgery. MATERIALS AND METHODS:This is a three-center prospective study which examined 173 men hav...

journal_title：Andrology

authors： Cavallini G,Scroppo FI,Colpi GM

更新日期：2019-01-01 00:00:00

abstract：:Increasing evidence disclosed the existence of a novel multi-organ endocrine pathway, involving bone, pancreas and testis, of high penetrance in energy metabolism and male fertility. The main mediator of this axis is undercarboxylated osteocalcin (ucOC), a bone-derived protein-exerting systemic effects on tissues expr...

journal_title：Andrology

authors： De Toni L,Di Nisio A,Rocca MS,De Rocco Ponce M,Ferlin A,Foresta C

更新日期：2017-07-01 00:00:00

abstract：:Male factor etiology may be a contributing factor in up to 60% of infertility cases. Dietary intake of phytoestrogens has been related to abnormal semen quality and hormone levels. However, its effect on couple fecundity is still unclear. Intake of soy products was assessed in 184 men from couples undergoing infertili...

journal_title：Andrology

authors： Mínguez-Alarcón L,Afeiche MC,Chiu YH,Vanegas JC,Williams PL,Tanrikut C,Toth TL,Hauser R,Chavarro JE

更新日期：2015-07-01 00:00:00

abstract：:The second messenger cyclic adenosine monophosphate (cAMP) has a central role in sperm physiology. Extracellular cAMP can be sequentially degraded into 5'AMP and adenosine by ecto-phosphodiesterases (ecto-PDE) and ecto-nucleotidases, a phenomenon called extracellular cAMP-adenosine pathway. As cAMP-adenosine pathway i...

journal_title：Andrology

authors： Bergeron A,Aragon JP,Guillemette C,Hébert A,Sullivan R,Blondin P,Richard FJ

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:The current results of in vitro reproduction techniques in pigs, such as in vitro fertilization (IVF) and embryo development, show high performance with both epididymal and ejaculated spermatozoa. However, the results using ejaculated spermatozoa are even better. Ejaculated spermatozoa are exposed to the sec...

journal_title：Andrology

authors： Soriano-Úbeda C,Avilés-López K,García-Vázquez FA,Romero-Aguirregomezcorta J,Matás C

更新日期：2021-01-01 00:00:00

abstract：:Prevalence and risk factors of concomitant primary low sexual desire/interest (LSD/I) and subsequent new-onset erectile dysfunction (ED) in men have been only partially investigated. We looked at the sociodemographic and clinical predictors of the concomitant condition of primary LSD/I - defined as the reduction in th...

journal_title：Andrology

authors： Salonia A,Clementi MC,Ventimiglia E,Colicchia M,Capogrosso P,Castiglione F,Castagna G,Boeri L,Suardi N,Cantiello F,Damiano R,Montorsi F

更新日期：2014-09-01 00:00:00

abstract：:Humanin (HN) has cytoprotective action on male germ cells after testicular stress induced by heat and hormonal deprivation. To examine whether HN has protective effects on chemotherapy-induced male germ cell apoptosis, we treated four groups of adult rats with (i) vehicle (control), (ii) HN, (iii) cyclophosphamide (CP...

journal_title：Andrology

authors： Surampudi P,Chang I,Lue Y,Doumit T,Jia Y,Atienza V,Liu PY,Swerdloff RS,Wang C

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Testicular germ cell tumour is the most common cancer to be diagnosed among young men. In New Zealand, we have observed some puzzling trends in the epidemiology of this disease. METHODS:We have conducted a narrative review of available evidence regarding the puzzling epidemiology of testicular germ cell tum...

journal_title：Andrology

authors： Gurney JK

更新日期：2019-07-01 00:00:00

abstract：:Scarce data are available on epidemiology of varicocoele, the most common surgically correctable cause of male infertility. The objectives of this study were to evaluate the association between body mass index (BMI) and varicocoele and to assess trends in prevalence over time. We conducted a nationwide population-base...

journal_title：Andrology

authors： Rais A,Zarka S,Derazne E,Tzur D,Calderon-Margalit R,Davidovitch N,Afek A,Carel R,Levine H

更新日期：2013-09-01 00:00:00

abstract：:Zona pellucida-based induction of acrosome reaction (AR) is a popular and well-accepted hypothesis. However, this hypothesis is being challenged in recent years and it has been proposed that the cumulus cells might be the site of AR. In our previous study, we reported the presence of a synaptic protein Liprin α3 on sp...

journal_title：Andrology

authors： Joshi CS,Khan SA,Khole VV

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Men with congenital unilateral absence of vas deferens were reported to be mainly azoospermic, with both unilateral renal absence and mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) but some have neither. OBJECTIVES:To assess whether in infertile couples the male partners with co...

journal_title：Andrology

authors： Mieusset R,Bieth E,Daudin M,Isus F,Delaunay B,Bujan L,Monteil L,Fauquet I,Huyghe E,Hamdi SM

更新日期：2020-05-01 00:00:00

abstract：:Nitric oxide is a physiologic signal essential to penile erection. l-citrulline (l-Cit) is converted into l-arginine (l-Arg), the precursor from which nitric oxide is generated. The level of l-Arg and l-Cit in the field of male sexual function remains relatively underexplored. The aim of the study was to evaluate the ...

journal_title：Andrology

authors： Barassi A,Corsi Romanelli MM,Pezzilli R,Damele CA,Vaccalluzzo L,Goi G,Papini N,Colpi GM,Massaccesi L,Melzi d'Eril GV

更新日期：2017-03-01 00:00:00

abstract：:Escherichia coli (E. coli) is a common pathogen in epididymitis, which represents a prevalent entity in male reproductive tract infections (RTI). Although current treatment regimens using antibiotics are satisfactory, development of antimicrobial resistance by the pathogen represents a challenge in the management of R...

journal_title：Andrology

authors： Biswas B,Bhushan S,Rajesh A,Suraj SK,Lu Y,Meinhardt A,Yenugu S

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:The association between alcohol intake and male reproductive function is still controversial. In the frame of a prospective cohort study, designed to investigate the relation between life style and fertility, we performed a cross-sectional analysis of semen quality. METHODS:Men of subfertile couples, referr...

journal_title：Andrology

authors： Ricci E,Noli S,Ferrari S,La Vecchia I,Cipriani S,De Cosmi V,Somigliana E,Parazzini F

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Penile cancer represents a rare pathology whose natural history of treatment is poorly understood. OBJECTIVE:To illustrate the dynamic survival profiles in surgically treated patients with squamous cell carcinoma of the penis (SCCP) using the conditional survival (CS) estimates. MATERIALS AND METHODS:Patie...

journal_title：Andrology

authors： Liu W,Luo Y,Wang G,Li N,Wang Z,Lei J,Wang X

更新日期：2020-11-01 00:00:00

abstract：:The main aim of this work was to evaluate how supplementing freezing media with reduced glutathione (GSH) affected the 'in vivo' fertilizing ability of boar semen subjected to cryopreservation procedures. With this purpose, 12 ejaculates coming from 12 boars were cryopreserved in the presence or absence of 2 mm GSH, w...

journal_title：Andrology

authors： Estrada E,Rodríguez-Gil JE,Rocha LG,Balasch S,Bonet S,Yeste M

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Regulatory bodies recommend inconsistent ejaculatory abstinence lengths before semen analysis. The literature exploring the effect of ejaculatory abstinence length on the outcomes of intracytoplasmic sperm injection is scarce. OBJECTIVE:To study the influence of ejaculatory abstinence length on semen qualit...

journal_title：Andrology

authors： Borges E Jr,Braga DPAF,Zanetti BF,Iaconelli A Jr,Setti AS

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Testicular architecture and sperm production are supported by a complex network of communication between various cell types. These signals ensure fertility by: regulating spermatogonial stem/progenitor cells; promoting steroidogenesis; and driving male-specific differentiation of the gonad. Sertoli cells hav...

journal_title：Andrology

authors： Heinrich A,DeFalco T

更新日期：2020-07-01 00:00:00

abstract：:In cryptorchid boys, failures in germ cell development have been clearly established. Some studies reported some abnormalities in Sertoli cells morphology but the results regarding their endocrine secretion remain controversial. To compare testicular hormone levels in young boys with and without cryptorchidism, we per...

journal_title：Andrology

authors： Hamdi SM,Almont T,Galinier P,Mieusset R,Thonneau P

更新日期：2017-07-01 00:00:00

abstract：:Spermatogenesis involves the aggregated action of up to 2300 genes, any of which, could, potentially, provide targets for diagnostic tests of male factor infertility. Contrary to the previously proposed common variant hypothesis for common diseases such as male infertility, genome-wide association studies and targeted...

journal_title：Andrology

authors： Hotaling J,Carrell DT

更新日期：2014-05-01 00:00:00

abstract：:Pubertal gynecomastia is a common condition observed in up to 65% of adolescent males. It is usually idiopathic and tends to regress within 1-2 years. In this descriptive cross-sectional study, we investigated 25 adolescent males with prominent (>B3) and/or persistent (>2 years) pubertal gynecomastia (P/PPG) to determ...

journal_title：Andrology

authors： Paris F,Gaspari L,Mbou F,Philibert P,Audran F,Morel Y,Biason-Lauber A,Sultan C

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:We aimed to examine the effects of pre-operative blood values on varicocelectomy success. MATERIALS AND METHODS:A total of 130 patients who underwent varicocelectomy in our clinic were retrospectively analyzed. Operation success was defined as the return of all semen parameters (concentration, progressive m...

journal_title：Andrology

authors： Erdogan O,Ok F,Carkci S

更新日期：2021-01-21 00:00:00

abstract：BACKGROUND:Gene expression patterns along the epididymis are established by specific transcription factor networks that coordinate region-specific functions. In rodents, the epididymis can be divided in up to 19 segments. Based on gross anatomy, the human epididymis is divided into caput, corpus, and cauda segments tog...

journal_title：Andrology

authors： Légaré C,Sullivan R

更新日期：2020-05-01 00:00:00

abstract：:Erectile dysfunction (ED) is increasingly recognized as a public health problem. Several studies have reported the influence of the insertion/deletion (I/D) polymorphism in the Angiotensin-converting enzyme (ACE) gene on ED susceptibility, but the results remain controversial. To derive a more precise estimation of th...

journal_title：Andrology

authors： Zhang T,Li WL,He XF,Wu ZY,Liu LH,He SH,Wei AY

更新日期：2013-03-01 00:00:00

abstract：:Urethral stricture disease, pelvic fracture urethral injury (PFUI), and their various treatment options are associated with erectile dysfunction (ED). The etiology of urethral stricture disease is multifactorial and includes trauma, inflammatory, and iatrogenic causes. Posterior urethral injuries are commonly associat...

journal_title：Andrology

authors： Sangkum P,Levy J,Yafi FA,Hellstrom WJ

更新日期：2015-05-01 00:00:00

abstract：:Oxidation-reduction potential describes the balance between the oxidants and antioxidants in fluids including semen. Various artificial culture media are used in andrology and IVF laboratories for sperm preparation and to support the development of fertilized oocytes under in vitro conditions. The composition and cond...

journal_title：Andrology

authors： Panner Selvam MK,Henkel R,Sharma R,Agarwal A

更新日期：2018-03-01 00:00:00

abstract：:Tamoxifen is an off-label option to treat men for breast cancer, infertility, and idiopathic gynecomastia. Lately, tamoxifen has been proposed as a treatment to prevent gynecomastia in prostate cancer patients receiving antiandrogen therapy. We reviewed the adverse events (AEs) reported in studies of men prescribed ta...

journal_title：Andrology

authors： Wibowo E,Pollock PA,Hollis N,Wassersug RJ

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Maximum urinary flow rate (Qmax) is usually increased after holmium laser enucleation of the prostate (HoLEP). However, improvements vary between patients and results regarding potential predictors of Qmax after HoLEP are inconsistent. Thus, we investigated pre-operative variables including second to fourth ...

journal_title：Andrology

authors： Park IN,Kim TB

更新日期：2019-03-01 00:00:00

abstract：:To add new arguments concerning the origin of the sperm-head vacuoles observed under high magnification with interference contrast microscopy, we carried out in two patients with total globozoospermia confirmed using transmission electron microscopy (TEM), a detailed sperm morphometric analysis with high magnification...

journal_title：Andrology

authors： Gatimel N,Léandri RD,Foliguet B,Bujan L,Parinaud J

更新日期：2013-01-01 00:00:00