Endocrine and molecular investigations in a cohort of 25 adolescent males with prominent/persistent pubertal gynecomastia.

abstract：:Interactions between infertility and sexuality are numerous and complex. Infertile men may suffer from sexual dysfunction (SD) when undergoing an assisted reproductive technology programme. We undertook a review both in French and English of the available data on male SD when being diagnosed with a fertility problem w...

journal_title：Andrology

authors： Bechoua S,Hamamah S,Scalici E

更新日期：2016-05-01 00:00:00

abstract：:Testicular germ cell tumours (TGCT) typically contain high numbers of infiltrating immune cells, yet the functional nature and consequences of interactions between GCNIS (germ cell neoplasia in situ) or seminoma cells and immune cells remain unknown. A co-culture model using the seminoma-derived TCam-2 cell line and p...

journal_title：Andrology

authors： Klein B,Schuppe HC,Bergmann M,Hedger MP,Loveland BE,Loveland KL

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus is one of the risk factors for male subfertility/infertility. Malaysian propolis is reported to decrease hyperglycaemia in diabetic state. OBJECTIVES:The present study investigated the protective effect of Malaysian propolis on diabetes-induced subfertility/infertility. Additionally, its c...

journal_title：Andrology

authors： Nna VU,Bakar ABA,Ahmad A,Umar UZ,Suleiman JB,Zakaria Z,Othman ZA,Mohamed M

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Concerns exist about the effect of delaying treatment for prostate cancer (PCa) regarding both oncological and functional outcomes after radical prostatectomy (RP). OBJECTIVE:To assess the impact of time from diagnosis to RP on post-operative erectile function (EF) outcomes. MATERIALS AND METHODS:We analyz...

journal_title：Andrology

authors： Schifano N,Capogrosso P,Pozzi E,Ventimiglia E,Cazzaniga W,Matloob R,Gandaglia G,Dehò F,Briganti A,Montorsi F,Salonia A

更新日期：2020-03-01 00:00:00

abstract：:Increasing evidence disclosed the existence of a novel multi-organ endocrine pathway, involving bone, pancreas and testis, of high penetrance in energy metabolism and male fertility. The main mediator of this axis is undercarboxylated osteocalcin (ucOC), a bone-derived protein-exerting systemic effects on tissues expr...

journal_title：Andrology

authors： De Toni L,Di Nisio A,Rocca MS,De Rocco Ponce M,Ferlin A,Foresta C

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:The transcription factor DMRTB1 plays a pivotal role in coordinating the transition between mitosis and meiosis in murine germ cells. No reliable data are available for human testis. OBJECTIVES:The present study aims to examine the testicular expression pattern of DMRTB1 in men showing normal and impaired s...

journal_title：Andrology

authors： Hilbold E,Bergmann M,Fietz D,Kliesch S,Weidner W,Langeheine M,Rode K,Brehm R

更新日期：2019-07-01 00:00:00

abstract：:Erectile dysfunction (ED) is very prevalent in the older population, although the ageing-related mechanisms involved in the development of ED are poorly understood. We propose that age-induced differences in nerve- and endothelium-mediated smooth muscle contractility in the corpus cavernosum (CC) could be found betwee...

journal_title：Andrology

authors： Lafuente-Sanchis A,Triguero D,Garcia-Pascual A

更新日期：2014-07-01 00:00:00

abstract：:The published incidence of bilateral varicocoeles in adults is much higher than among adolescents. We investigated our adolescent varicocoele database to determine (i) the presence of subclinical and palpable right varicocoele s in boys with a left varicocoele, (ii) the effect, if any, of right varicocoele on asymmetr...

journal_title：Andrology

authors： Woldu S,Nees S,Van Batavia J,Spencer B,Glassberg K

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Regulatory bodies recommend inconsistent ejaculatory abstinence lengths before semen analysis. The literature exploring the effect of ejaculatory abstinence length on the outcomes of intracytoplasmic sperm injection is scarce. OBJECTIVE:To study the influence of ejaculatory abstinence length on semen qualit...

journal_title：Andrology

authors： Borges E Jr,Braga DPAF,Zanetti BF,Iaconelli A Jr,Setti AS

更新日期：2019-03-01 00:00:00

abstract：:Erectile Dysfunction is considered a multifactorial disease, where organic and psychological aspects are often interconnected. In a randomized controlled pilot study, we compared the efficacy of combined vardenafil orodispersible tablet (VARD) and cognitive-behavioral sex therapy (CBST) vs. VARD alone in improving sex...

journal_title：Andrology

authors： Boddi V,Castellini G,Casale H,Rastrelli G,Boni L,Corona G,Maggi M

更新日期：2015-09-01 00:00:00

abstract：:Erectile dysfunction (ED) is increasingly recognized as a public health problem. Several studies have reported the influence of the insertion/deletion (I/D) polymorphism in the Angiotensin-converting enzyme (ACE) gene on ED susceptibility, but the results remain controversial. To derive a more precise estimation of th...

journal_title：Andrology

authors： Zhang T,Li WL,He XF,Wu ZY,Liu LH,He SH,Wei AY

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between cannabis use and testicular function (as assessed through semen quality and serum hormone levels) in different populations. EVIDENCE REVIEW:Systematic review and meta-analysis of population-based retrospective cohort studies. PRISMA guidelines were used for abstracting dat...

journal_title：Andrology

authors： Belladelli F,Del Giudice F,Kasman A,Kold Jensen T,Jørgensen N,Salonia A,Eisenberg ML

更新日期：2020-11-29 00:00:00

abstract：:The second messenger cyclic adenosine monophosphate (cAMP) has a central role in sperm physiology. Extracellular cAMP can be sequentially degraded into 5'AMP and adenosine by ecto-phosphodiesterases (ecto-PDE) and ecto-nucleotidases, a phenomenon called extracellular cAMP-adenosine pathway. As cAMP-adenosine pathway i...

journal_title：Andrology

authors： Bergeron A,Aragon JP,Guillemette C,Hébert A,Sullivan R,Blondin P,Richard FJ

更新日期：2016-11-01 00:00:00

abstract：:Oxidation-reduction potential describes the balance between the oxidants and antioxidants in fluids including semen. Various artificial culture media are used in andrology and IVF laboratories for sperm preparation and to support the development of fertilized oocytes under in vitro conditions. The composition and cond...

journal_title：Andrology

authors： Panner Selvam MK,Henkel R,Sharma R,Agarwal A

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Previous studies suggested that sperm head shape may serve as an effective indicator of semen quality. However, there lacks research with large sample and quantitative measurement. OBJECTIVES:The objective of this retrospective study was to explore the association between sperm head elongation (Width/Length...

journal_title：Andrology

authors： Chen F,Gao L,Zhou H,Guo L,Chen Q,Gan Y,Sun X,Li Q,Wang K

更新日期：2019-11-01 00:00:00

abstract：:Our objective was to study the birth defect rates in intracytoplasmic morphologically selected sperm injection (IMSI) pregnancies. A cohort of couples presenting male factor infertility between January 2006 and January 2014 was retrospectively analyzed. Discharge letters and a telephone interview were performed for as...

journal_title：Andrology

authors： Hershko-Klement A,Sukenik-Halevy R,Biron Shental T,Miller N,Berkovitz A

更新日期：2016-09-01 00:00:00

abstract：:Scarce data are available on epidemiology of varicocoele, the most common surgically correctable cause of male infertility. The objectives of this study were to evaluate the association between body mass index (BMI) and varicocoele and to assess trends in prevalence over time. We conducted a nationwide population-base...

journal_title：Andrology

authors： Rais A,Zarka S,Derazne E,Tzur D,Calderon-Margalit R,Davidovitch N,Afek A,Carel R,Levine H

更新日期：2013-09-01 00:00:00

abstract：:Sickle cell disease (SCD)-associated priapism is characterized by decreased nitric oxide (NO) signaling and downregulated phosphodiesterase (PDE)5 protein expression and activity in the penis. Priapism is also associated with testosterone deficiency, but molecular mechanisms underlying testosterone effects in the peni...

journal_title：Andrology

authors： Musicki B,Karakus S,Akakpo W,Silva FH,Liu J,Chen H,Zirkin BR,Burnett AL

更新日期：2018-01-01 00:00:00

abstract：:Tamoxifen is an off-label option to treat men for breast cancer, infertility, and idiopathic gynecomastia. Lately, tamoxifen has been proposed as a treatment to prevent gynecomastia in prostate cancer patients receiving antiandrogen therapy. We reviewed the adverse events (AEs) reported in studies of men prescribed ta...

journal_title：Andrology

authors： Wibowo E,Pollock PA,Hollis N,Wassersug RJ

更新日期：2016-09-01 00:00:00

abstract：:Defects in bone regulatory pathways have been linked to chronic diseases including cardiovascular disease and cancer. In men, a link between bone metabolism and gonadal hormones has been suggested. However, to date, there is lack of evidence on the association between serum inorganic phosphate (Pi) and sex steroid hor...

journal_title：Andrology

authors： Wulaningsih W,Van Hemelrijck M,Michaelsson K,Kanarek N,Nelson WG,Ix JH,Platz EA,Rohrmann S

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:The presence of miRNAs in human reproductive tissue is intriguing and suggests the possibility that these important regulatory molecules play a role in reproductive function. However, the regulatory role of miRNAs in reproductive tissue remains poorly understood with a significant amount of controversial and...

journal_title：Andrology

authors： Salas-Huetos A,James ER,Aston KI,Carrell DT,Jenkins TG,Yeste M

更新日期：2020-01-01 00:00:00

abstract：:Tributyltin (TBT), a pesticide used in antifouling paints, is toxic for aquatic invertebrates. In vertebrates, TBT may act in obesogen- inducing adipogenetic gene transcription for adipocyte differentiation. In a previous study, we demonstrated that acute administration of TBT induces c-fos expression in the arcuate n...

journal_title：Andrology

authors： Bo E,Farinetti A,Marraudino M,Sterchele D,Eva C,Gotti S,Panzica G

更新日期：2016-07-01 00:00:00

abstract：:Humanin (HN) has cytoprotective action on male germ cells after testicular stress induced by heat and hormonal deprivation. To examine whether HN has protective effects on chemotherapy-induced male germ cell apoptosis, we treated four groups of adult rats with (i) vehicle (control), (ii) HN, (iii) cyclophosphamide (CP...

journal_title：Andrology

authors： Surampudi P,Chang I,Lue Y,Doumit T,Jia Y,Atienza V,Liu PY,Swerdloff RS,Wang C

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Gene expression patterns along the epididymis are established by specific transcription factor networks that coordinate region-specific functions. In rodents, the epididymis can be divided in up to 19 segments. Based on gross anatomy, the human epididymis is divided into caput, corpus, and cauda segments tog...

journal_title：Andrology

authors： Légaré C,Sullivan R

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Men with congenital unilateral absence of vas deferens were reported to be mainly azoospermic, with both unilateral renal absence and mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) but some have neither. OBJECTIVES:To assess whether in infertile couples the male partners with co...

journal_title：Andrology

authors： Mieusset R,Bieth E,Daudin M,Isus F,Delaunay B,Bujan L,Monteil L,Fauquet I,Huyghe E,Hamdi SM

更新日期：2020-05-01 00:00:00

abstract：:Cell-free seminal RNA (cfs-RNA) is mixed transcripts derived from male reproductive organs, and is potential biomarker for the research and diagnosis of male reproductive-related diseases. However, some clinical factors, including age, asymptomatic Ureaplasma urealyticum (UU) infection, scrotal heat stress, abstinence...

journal_title：Andrology

authors： Dong TT,Yu Q,Qing XR,Ma XL,Dong WW,Shi J,Li HG

更新日期：2016-11-01 00:00:00

abstract：:Highly active antiretroviral therapy has evolved over the years, leading to a boost in the quality of life in people living with HIV and AIDS. However, growing evidence has shown that highly active antiretroviral therapy has deleterious effects on the testes and the overall reproductive capacity. Therefore, this study...

journal_title：Andrology

authors： Adana MY,Akang EN,Peter AI,Jegede AI,Naidu ECS,Tiloke C,Chuturgoon AA,Azu OO

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:A significant increase in the use of intracytoplasmic sperm injection (ICSI) since its introduction in 1992 has been observed worldwide, including beyond its original intended use for severe male factor infertility. Concerns regarding ICSI include the effects of poor quality spermatozoa on offspring health a...

journal_title：Andrology

authors： Catford SR,McLachlan RI,O'Bryan MK,Halliday JL

更新日期：2018-09-01 00:00:00

abstract：:Scrotal skin is thin and has high steroid permeability, but the pharmacokinetics of testosterone via the scrotal skin route has not been studied in detail. The aim of this study was to define the pharmacokinetics of testosterone delivered via the scrotal skin route. The study was a single-center, three-phase cross-ove...

journal_title：Andrology

authors： Iyer R,Mok SF,Savkovic S,Turner L,Fraser G,Desai R,Jayadev V,Conway AJ,Handelsman DJ

更新日期：2017-07-01 00:00:00

abstract：:Estrogens are involved in growth, differentiation and pathogenesis of human prostate through the mediation of the classical estrogen receptors ERα and ERβ. The G protein-coupled estrogen receptor (GPER) is a 'novel' mediator of estrogen signaling which has been recently recognized in some human reproductive tissues, b...

journal_title：Andrology

authors： Rago V,Romeo F,Giordano F,Ferraro A,Carpino A

更新日期：2016-01-01 00:00:00