Reward disrupts reactivated human skill memory.

Abstract:

:Accumulating evidence across species and memory domains shows that when an existing memory is reactivated, it becomes susceptible to modifications. However, the potential role of reward signals in these mechanisms underlying human memory dynamics is unknown. Leaning on a wealth of findings on the role of reward in reinforcing memory, we tested the impact of reinforcing a skill memory trace with monetary reward following memory reactivation, on strengthening of the memory trace. Reinforcing reactivated memories did not strengthen the memory, but rather led to disruption of the memory trace, breaking down the link between memory reactivation and subsequent memory strength. Statistical modeling further revealed a strong mediating role for memory reactivation in linking between memory encoding and subsequent memory strength only when the memory was replayed without reinforcement. We suggest that, rather than reinforcing the existing memory trace, reward creates a competing memory trace, impairing expression of the original reward-free memory. This mechanism sheds light on the processes underlying skill acquisition, having wide translational implications.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Dayan E,Laor-Maayany R,Censor N

doi

10.1038/srep28270

subject

Has Abstract

pub_date

2016-06-16 00:00:00

pages

28270

issn

2045-2322

pii

srep28270

journal_volume

6

pub_type

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