Abstract:
BACKGROUND:Due to higher transthoracic impedance, obese patients may be less likely to be successfully defibrillated from ventricular tachycardia or ventricular fibrillation (VT/VF) arrest. However, the association between patient body mass index (BMI), defibrillation success, and survival outcomes of VT/VF arrest are poorly understood. METHODS:We evaluated 7110 patients with in-hospital VT/VF arrest at 286 hospitals within the Get With The Guidelines(®)-Resuscitation (GWTG-R) Multicenter Observational Registry between 2006 and 2012. Patients were categorized as underweight (BMI<18.5kg/m(2)), normal weight (BMI 18.5-24.9kg/m(2)), over-weight (BMI 25.0-29.9kg/m(2)), obese (BMI 30.0-34.9kg/m(2)), and extremely obese (BMI≥35.0kg/m(2)). Using generalized linear mixed regression, we determined the risk-adjusted relationship between BMI and patient outcomes while accounting for clustering by hospitals. The primary outcome was successful first shock defibrillation (a post-shock rhythm other than VT/VF) with secondary outcomes of return of spontaneous circulation, survival to 24h, and survival to discharge. RESULTS:Among adult patients suffering VT/VF arrest, 304 (4.3%) were underweight, 2061 (29.0%) were normal weight, 2139 (30.1%) were overweight, and 2606 (36.6%) were obese or extremely obese. In a risk-adjusted analysis, we observed no interaction between BMI and energy level for the successful termination of VT/VF with first shock. Furthermore, the risk-adjusted likelihood of successful first shock termination of VT/VF did not differ significantly across BMI categories. Finally, when compared to overweight patients, obese patients had similar risk-adjusted likelihood of survival to hospital discharge (odds ratio 0.786, 95% confidence interval 0.593-1.043). CONCLUSIONS:There was no significant difference in the likelihood of successful defibrillation with the first shock attempt among different BMI categories.
journal_name
Resuscitationjournal_title
Resuscitationauthors
Ogunnaike BO,Whitten CW,Minhajuddin A,Melikman E,Joshi GP,Moon TS,Schneider PM,Bradley SM,American Heart Association's Get With The Guidelines(®)-Resuscitation Investigators.doi
10.1016/j.resuscitation.2016.05.028subject
Has Abstractpub_date
2016-08-01 00:00:00pages
156-60eissn
0300-9572issn
1873-1570pii
S0300-9572(16)30093-4journal_volume
105pub_type
杂志文章相关文献
RESUSCITATION文献大全abstract:OBJECTIVES:Conflicting data exists regarding the association between sex and mortality in adults with in-hospital (IHCA) and out-of-hospital cardiac arrest (OHCA). We therefore conducted a meta-analysis to investigate the association between sex and mortality in adults with IHCA and OHCA. METHODS:We systematically sea...
journal_title:Resuscitation
pub_type: 杂志文章,评审
doi:10.1016/j.resuscitation.2020.07.031
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVES:Mild therapeutic hypothermia (TH) has been shown to improve neurologic outcome in patients experiencing cardiac arrest after return of spontaneous circulation (ROSC). The best timing to initiate TH is currently not known. The aim of this study by the ICE (Italian Cooling Experience) group was to investigate ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2011.12.002
更新日期:2012-07-01 00:00:00
abstract:AIM:The whole body ischaemia-reperfusion after cardiac arrest (CA) induces a systemic inflammation-reperfusion response. The expression of urokinase plasminogen activator receptor (uPAR) is known to be induced after hypoxia and increased levels of soluble form suPAR have been measured after hypoxia and ischaemia. Our a...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2014.08.017
更新日期:2014-11-01 00:00:00
abstract::This study evaluated the competence of students of the healthcare professions to locate the carotid pulse using a computerised manikin, within 10 s. A sample of 105 students from physiotherapy, radiography, midwifery and nursing participated in measuring diagnostic accuracy in a single attempt at pulse check using a c...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/s0300-9572(00)00139-8
更新日期:2000-05-01 00:00:00
abstract:BACKGROUND:Extracorporeal cardiopulmonaryresuscitation (ECPR) is emerging as a viable rescue strategy for refractory out-of-hospital cardiac arrest. In the U.S., limited training of emergency medicine providers is a barrier to widespread implementation. AIMS:Test the hypothesis that emergency medicine physicians and n...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2019.03.002
更新日期:2019-05-01 00:00:00
abstract:AIM:In this study, we sought to quantitatively describe the survival outcomes, incidence rates, and predictors of survival after paediatric traumatic out-of-hospital cardiac arrest (OHCA). METHODS:We systematically searched MEDLINE, EMBASE, EMCARE, and CINAHL to identify observational or interventional studies reporti...
journal_title:Resuscitation
pub_type: 杂志文章,评审
doi:10.1016/j.resuscitation.2020.01.037
更新日期:2020-04-01 00:00:00
abstract:AIM:This study aimed to investigate the effects of dispatcher-initiated telephone cardiopulmonary resuscitation (TCPR) in Japan using a nationwide population-based registry. METHODS:Adult Japanese patients with out-of-hospital cardiac arrest (OHCA; n = 582,483, age ≥18 years) were selected from a nationwide Utstein-st...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2019.08.031
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:The electroencephalograph (EEG) pattern of burst suppression with identical bursts (BSIB), with or without myoclonus, occurs often after resuscitation from cardiac arrest. These patterns are associated with severe brain injury but their neuropathological basis is unknown. Using EEG source localization, we te...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2020.10.029
更新日期:2020-10-27 00:00:00
abstract:THE AIM OF THE STUDY:There are limited data on blood pressure targets and vasopressor use following cardiac arrest. We hypothesized that hypotension and high vasopressor load are associated with poor neurological outcome following out-of-hospital cardiac arrest (OHCA). METHODS:We included 412 patients with OHCA includ...
journal_title:Resuscitation
pub_type: 杂志文章,多中心研究
doi:10.1016/j.resuscitation.2016.05.026
更新日期:2016-08-01 00:00:00
abstract:AIM:To assess the effectiveness of the ILCOR Advisory Statements on Advanced Life Support adopted by the Resuscitation Council (UK), as the standard for resuscitation following cardiac arrest. METHOD:Over the period May to November 1997, data on the process and outcome of cardiopulmonary resuscitation following in-hos...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/s0300-9572(00)00212-4
更新日期:2000-10-01 00:00:00
abstract:OBJECTIVE:the aim of the study is to investigate the effect of thrombolytic therapy on neurological outcome in patients after cardiac arrest due to acute myocardial infarction. Laboratory investigations have demonstrated that thrombolytic therapy after cardiopulmonary resuscitation improves neurological function. METH...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/s0300-9572(01)00432-4
更新日期:2002-01-01 00:00:00
abstract::Manikins currently used in newborn and paediatric resuscitation training are limited in their effectiveness by an inability to allow instructors control over airway patency. This means that attempts to introduce situations that require interventions, other than just appropriate head positioning to achieve successful l...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/s0300-9572(02)00124-7
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND:Sudden cardiac arrest (SCA) is a major public health challenge in the United States (US). At present, the existence of limited literature on psychological sequelae post-cardiac arrest is a challenge in providing optimal care to survivors. AIM:The aim of this study is to determine the prevalence of various p...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2019.01.035
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVE:To assess the possibility of heart rate variability (HRV) measures as predictors of 24-h mortality in successfully resuscitated patients with out-of-hospital cardiac arrest (OHCA). METHODS:This prospective cohort study was conducted at a 40-bed emergency department (ED) of a university-affiliated medical cen...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2009.06.020
更新日期:2009-10-01 00:00:00
abstract::The emergency call for resuscitation in a children's hospital is reported. Forty-seven resuscitation attempts via the emergency call were made in 43 patients over the past 5 years; 24 out of 43 patients had heart diseases. Cardiac patients were more likely to die within a few days after their resuscitation. The patien...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/0300-9572(85)90022-x
更新日期:1985-06-01 00:00:00
abstract:OBJECTIVES:This study investigated sustained abdominal compression as a means to improve coronary perfusion pressure (CPP) during cardiopulmonary resuscitation (CPR) and compared the resulting CPP augmentation with that achieved using vasopressor drugs. METHOD:During electrically induced ventricular fibrillation in an...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2007.05.012
更新日期:2007-12-01 00:00:00
abstract:PURPOSE:Chest compressions are often performed at a variable rate during cardiopulmonary resuscitation (CPR). The effect of compression rate on other chest compression quality variables (compression depth, duty-cycle, leaning, performance decay over time) is unknown. This randomised controlled cross-over manikin study ...
journal_title:Resuscitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.resuscitation.2011.07.012
更新日期:2012-03-01 00:00:00
abstract::"Bystanders" or lay persons are typically the first caregivers to attend to a victim of out-of-hospital cardiopulmonary arrest. Astronaut crew medical officers (CMO) play a similar role to bystanders aboard the International Space Station (ISS). Studies have demonstrated the importance of bystander cardiopulmonary res...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2006.07.027
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVES:In cardiac arrest patients (in hospital and pre hospital) does resuscitation produce a good Quality of Life (QoL) for survivors after discharge from the hospital? METHODS:Embase, Medline, The Cochrane Database of Systematic Reviews, Academic Search Premier, the Central Database of Controlled Trials and the ...
journal_title:Resuscitation
pub_type: 杂志文章,评审
doi:10.1016/j.resuscitation.2010.10.030
更新日期:2011-03-01 00:00:00
abstract::Cardiopulmonary homeostasis for the high risk surgical patient is dependent on invasive monitoring techniques which are designed to allow for the early detection of physiological dysfunction during the development stages. One must maintain both minimum and maximum predetermined cardiorespiratory values by the early ut...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/0300-9572(84)90014-5
更新日期:1984-03-01 00:00:00
abstract:AIMS OF THE STUDY:Post-cardiac arrest resuscitated patients often develop a "sepsis-like" syndrome, which may be associated with organ dysfunction. Impaired microcirculatory blood flow is thought to play a key role in sepsis-induced organ failure; however, few data are available on the microcirculation after cardiac ar...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2011.02.018
更新日期:2011-06-01 00:00:00
abstract::Cell-free DNA has been associated with outcome in several acute conditions including two reports concerning the outcomes after cardiac arrest that found association of circulating DNA quantities at admission with mortality. The origins of cell-free DNA are primarily necrosis and apoptosis, which in cardiac arrest occu...
journal_title:Resuscitation
pub_type: 杂志文章,多中心研究
doi:10.1016/j.resuscitation.2013.10.008
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:For out-of-hospital cardiac arrest (OHCA) to be predicted and prevented, it is imperative the healthcare system has access to those vulnerable before the event occurs. We aimed to determine the extent of contact to the healthcare system before OHCA. METHODS:All patients in Denmark with a registered OHCA Jun...
journal_title:Resuscitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.resuscitation.2010.06.025
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Environmental carbon dioxide (CO) detectors used as an early warning method have been adapted to measure CO concentration in expired breath. This technique has been validated in smokers with relatively low CO concentrations, but its applicability to poisoning has not been demonstrated. OBJECTIVE:To compare ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2004.08.018
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVES:The timing of and interval between events in prehospital care is important for system design, patient outcome, and prehospital research. Since these data can guide treatment recommendations, it is imperative that time-based prehospital documentation is accurate and precise, especially for time-sensitive cond...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2014.05.002
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVE:The placement of defibrillation pads at ideal anatomical sites is one of the major determinants of transthoracic defibrillation success. However, the optimal pads position for ventricular defibrillation is still undetermined. In the present study, we compared the effects of two different pads positions on def...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2011.12.010
更新日期:2012-06-01 00:00:00
abstract:AIM:The American Heart Association (AHA) and the Institute of Medicine have published a national "call-to-action" to improve survival from in-hospital cardiopulmonary arrest (IHCA). Our aim was to determine if more-active hospital participation in standardized in-situ mock code (ISMC) training is associated with increa...
journal_title:Resuscitation
pub_type: 杂志文章,多中心研究
doi:10.1016/j.resuscitation.2018.09.020
更新日期:2018-12-01 00:00:00
abstract:AIM:Cardiopulmonary resuscitation (CPR) guidelines recommend specific chest compression (CC) target depths for children. We quantitatively describe relative anterior-posterior diameter (APD) depth, actual depth, and force of CCs during real CPR events in children. METHODS:CC depth and force were recorded during real C...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2011.10.014
更新日期:2012-03-01 00:00:00
abstract:AIM:Various methods, including self-instruction, have been used to try to improve the acquisition of basic life support skills. This is a preliminary report of the effectiveness of a web-based self-training program for BLS and the use of an AED. METHODS:Sixteen volunteers completed on-line training in their own time o...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2007.05.014
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND/AIMS:Echocardiographic abnormalities are common after resuscitation from cardiac arrest. The association between echocardiographic findings with vasopressor requirements and mortality are not well described. We sought to determine the associations between echocardiographic abnormalities and mortality, vasopr...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2016.06.028
更新日期:2016-09-01 00:00:00