Paediatric traumatic out-of-hospital cardiac arrest: A systematic review and meta-analysis.


AIM:In this study, we sought to quantitatively describe the survival outcomes, incidence rates, and predictors of survival after paediatric traumatic out-of-hospital cardiac arrest (OHCA). METHODS:We systematically searched MEDLINE, EMBASE, EMCARE, and CINAHL to identify observational or interventional studies reporting relevant data for paediatric traumatic OHCA. The Joanna Briggs Institute critical appraisal tool for prognostic studies was used to assess study quality. We analysed the survival outcomes and pooled incidence rates per 100,000 person-years using random-effect models. RESULTS:Nineteen articles met the eligibility criteria involving 705 Emergency Medical Service (EMS)-attended and 973 EMS-treated traumatic paediatric OHCAs across an estimated serviceable population of 15.2 million. Four studies were conducted in the Asia-pacific region, seven in Europe, and eight in North America. Nine studies were assessed as low quality. Overall pooled survival to hospital discharge or 30-day survival for the EMS-treated cases was 1.2% (n = 6 studies; 95% confidence interval (CI): 0.1%, 3.1%; I2 = 26.1%). The pooled rate of return of spontaneous circulation in four studies was 22.1% (95% CI: 18.4%, 26.1%; I2 = 0.0%), and the pooled rate of event survival was 18.8% (n = 3 studies; 95% CI: 15.2%, 22.7%; I2 = 0.0%). The pooled incidence of EMS-treated paediatric traumatic OHCA was 1.6 cases per 100,000 person-years (n = 10 studies; 95% CI: 1.1, 2.2; I2 = 98.1%). No study reported on the impact of epidemiological or clinical factors on survival. CONCLUSION:Survival outcomes of paediatric traumatic OHCA are poor and existing studies report varying incidence rates. The absence of large prospective and international registry data hinders the development of novel strategies to improve survival rates.






Alqudah Z,Nehme Z,Alrawashdeh A,Williams B,Oteir A,Smith K




Has Abstract


2020-04-01 00:00:00












  • Long-Term Survival Trends of Medicare Patients After In-Hospital Cardiac Arrest: Insights from Get With The Guidelines-Resuscitation®.

    abstract:BACKGROUND:Although rates of survival to hospital discharge after in-hospital cardiac arrest (IHCA) have improved over the last decade, it is unknown if these survival gains are sustained after hospital discharge. OBJECTIVE:To examine 1-year survival trends overall and by rhythm after IHCA. METHODS:Using Medicare ben...


    pub_type: 杂志文章


    authors: Thompson LE,Chan PS,Tang F,Nallamothu BK,Girotra S,Perman SM,Bose S,Daugherty SL,Bradley SM,American Heart Association’s Get With the Guidelines-Resuscitation Investigators.

    更新日期:2018-02-01 00:00:00

  • The contribution of comorbidity and medication use to poor outcome from out-of-hospital cardiac arrest at home locations.

    abstract:INTRODUCTION:Out-of-hospital cardiac arrest (OHCA) at home is associated with lower rates of shockable initial rhythm and survival than OHCA in a public location. We determined whether medical history and medication use explain the association between OHCA location and presence of shockable initial rhythm and survival ...


    pub_type: 杂志文章


    authors: Hulleman M,Oving I,Homma PCM,Beesems SG,Tan HL,Koster RW,Blom MT

    更新日期:2020-06-01 00:00:00

  • Systematic review and meta-analysis of hemodynamic-directed feedback during cardiopulmonary resuscitation in cardiac arrest.

    abstract:BACKGROUND/OBJECTIVE:Physiologic monitoring of resuscitative efforts during cardiac arrest is gaining in importance, as it provides a real-time window into the cellular physiology of patients. The aim of this review is to assess the quality of evidence surrounding the use of physiologic monitoring to guide cardiopulmon...


    pub_type: 杂志文章,meta分析,评审


    authors: Chopra AS,Wong N,Ziegler CP,Morrison LJ

    更新日期:2016-04-01 00:00:00

  • EEG reactivity to pain in comatose patients: Importance of the stimulus type.

    abstract:INTRODUCTION:Electroencephalogram (EEG) background reactivity is a potentially interesting outcome predictor in comatose patients, especially after cardiac arrest, but recent studies report only fair interrater reliability. Furthermore, there are no definite guidelines for its testing. We therefore investigated the EEG...


    pub_type: 杂志文章


    authors: Tsetsou S,Novy J,Oddo M,Rossetti AO

    更新日期:2015-12-01 00:00:00

  • Efficacy of therapeutic hypothermia after out-of-hospital cardiac arrest due to ventricular fibrillation.

    abstract:AIM OF THE STUDY:We investigated implementation and efficacy of mild therapeutic hypothermia in the treatment of out-of-hospital cardiac arrest due to ventricular fibrillation. MATERIALS AND METHODS:Two periods were compared, an historical one (36 patients) between 2000 and 2002 where therapeutic hypothermia was never...


    pub_type: 杂志文章


    authors: Belliard G,Catez E,Charron C,Caille V,Aegerter P,Dubourg O,Jardin F,Vieillard-Baron A

    更新日期:2007-11-01 00:00:00

  • Five years experience of cardiopulmonary resuscitation in a children's hospital.

    abstract::The emergency call for resuscitation in a children's hospital is reported. Forty-seven resuscitation attempts via the emergency call were made in 43 patients over the past 5 years; 24 out of 43 patients had heart diseases. Cardiac patients were more likely to die within a few days after their resuscitation. The patien...


    pub_type: 杂志文章


    authors: Horimoto Y,Yoshizawa M,Okazaki A,Hasumi K

    更新日期:1985-06-01 00:00:00

  • History of diabetes mellitus as a neurologic predictor in comatose survivors of cardiac arrest of cardiac origin treated with mild hypothermia.

    abstract:AIM:To investigate the impact of a history of diabetes mellitus on the neurologic outcome in comatose survivors of cardiac arrest of cardiac origin treated with mild hypothermia. METHODS:A prospective observational study was performed between September 2003 and July 2008. Eighty comatose survivors of cardiac arrest of...


    pub_type: 杂志文章


    authors: Kagawa E,Inoue I,Kawagoe T,Ishihara M,Shimatani Y,Kurisu S,Nakama Y,Maruhashi T,Dai K,Matsushita J,Ikenaga H

    更新日期:2009-08-01 00:00:00

  • Team performance in the emergency room: assessment of inter-disciplinary attitudes.

    abstract::In-hospital emergency medicine in central Europe relies on inter-disciplinary co-operation. To improve team performance in the emergency room (ER), a questionnaire for assessment of attitudes and judgements in resuscitation procedures was developed. A total of 43 items were evaluated according to a five-point Likert s...


    pub_type: 杂志文章


    authors: Ummenhofer W,Amsler F,Sutter PM,Martina B,Martin J,Scheidegger D

    更新日期:2001-04-01 00:00:00

  • Low rates of immediate coronary angiography among young adults resuscitated from sudden cardiac arrest.

    abstract:AIM:Coronary artery disease (CAD) has recently been emphasized as a major cause of sudden cardiac arrest (SCA) in young adults. We aim to assess the rate of immediate coronary angiography performance in young patients resuscitated from SCA. METHODS:From May 2011 to May 2017, all cases of out-of-hospital SCA aged 18-40...


    pub_type: 杂志文章


    authors: Waldmann V,Karam N,Rischard J,Bougouin W,Sharifzadehgan A,Dumas F,Narayanan K,Sideris G,Voicu S,Gandjbakhch E,Jost D,Lamhaut L,Ludes B,Plu I,Beganton F,Wahbi K,Varenne O,Megarbane B,Algalarrondo V,Extramiana F,Lel

    更新日期:2020-02-01 00:00:00

  • Feasibility of bispectral index monitoring to guide early post-resuscitation cardiac arrest triage.

    abstract:INTRODUCTION:Triage after resuscitation from cardiac arrest is hindered by reliable early estimation of brain injury. We evaluated the performance of a triage model based on early bispectral index (BIS) findings and cardiac risk classes. METHODS:Retrospective evaluation of serial patients resuscitated from cardiac arr...


    pub_type: 杂志文章


    authors: Seder DB,Dziodzio J,Smith KA,Hickey P,Bolduc B,Stone P,May T,McCrum B,Fraser GL,Riker RR

    更新日期:2014-08-01 00:00:00

  • iCPR: a new application of high-quality cardiopulmonary resuscitation training.

    abstract:OBJECTIVES:The present study evaluates a new CPR feedback application for the iPhone (iCPR) designed to improve chest compression performance tested in a cardiac arrest simulation to evaluate performance and acceptance by healthcare professionals and lay people. METHODS:We built an application specifically dedicated t...


    pub_type: 杂志文章


    authors: Semeraro F,Taggi F,Tammaro G,Imbriaco G,Marchetti L,Cerchiari EL

    更新日期:2011-04-01 00:00:00

  • The relationship between time to arrival of emergency medical services (EMS) and survival from out-of-hospital ventricular fibrillation cardiac arrest.

    abstract:AIM:We examined the relationship between time from collapse to arrival of emergency medical services (EMS) and survival to hospital discharge for out-of-hospital ventricular fibrillation cardiac arrests in order to determine meaningful interpretations of this association. METHODS:We calculated survival rates in 1-min ...


    pub_type: 杂志文章


    authors: Gold LS,Fahrenbruch CE,Rea TD,Eisenberg MS

    更新日期:2010-05-01 00:00:00

  • Comparison of brain computed tomography and diffusion-weighted magnetic resonance imaging to predict early neurologic outcome before target temperature management comatose cardiac arrest survivors.

    abstract:AIM:We previously reported that diffusion-weighted magnetic resonance imaging (DW-MRI) could be used to predict neurologic outcomes before targeted temperature management (TTM) after return of spontaneous circulation (ROSC) from cardiac arrest (CA). We compared the efficacy of brain computed tomography (CT) and DW-MRI ...


    pub_type: 杂志文章


    authors: Jeon CH,Park JS,Lee JH,Kim H,Kim SC,Park KH,Yi KS,Kim SM,Youn CS,Kim YM,Lee BK

    更新日期:2017-09-01 00:00:00

  • The effects of an automatic, low pressure and constant flow ventilation device versus manual ventilation during cardiovascular resuscitation in a porcine model of cardiac arrest.

    abstract:BACKGROUND:Cardiac arrest is an important cause of mortality. Cardiopulmonary resuscitation (CPR) improves survival, however, delivery of effective CPR can be challenging and combining effective chest compressions with ventilation, while avoiding over-ventilation is difficult. We hypothesized that ventilation with a pn...


    pub_type: 杂志文章


    authors: Hu X,Ramadeen A,Laurent G,So PP,Baig E,Hare GM,Dorian P

    更新日期:2013-08-01 00:00:00

  • Comparison of sodium bicarbonate with dichloroacetate treatment of hyperlactatemia and lactic acidosis in the ischemic rat.

    abstract::Serum lactic acidosis is characterized by a pH less than 7.25 and lactate greater than 5 mEq. Although sodium bicarbonate (NaHCO3) is standard treatment for this condition, clinical and experimental studies suggest that high doses of NaHCO3 may be ineffectual or even detrimental to brain, cardiovascular, and respirato...


    pub_type: 杂志文章


    authors: Dimlich RV,Biros MH,Widman DW,Kaplan J

    更新日期:1988-01-01 00:00:00

  • Low serum Kallistatin level was associated with poor neurological outcome of out-of-hospital cardiac arrest survivors: Proteomics study.

    abstract:AIM OF THE STUDY:To identify proteins of which depletion are associated with the poor 6-month neurological outcome of out-of-hospital cardiac arrest survivors. METHODS:Seven healthy volunteers and 34 out-of-hospital cardiac arrest survivors admitted to the intensive care unit (ICU) and underwent targeted-temperature m...


    pub_type: 杂志文章


    authors: Jung YS,Kwon WY,Suh GJ,Moon S,Han MH,Youn JI,Seo SU,Kim KS,Seong SY

    更新日期:2018-07-01 00:00:00

  • A pilot study of mechanical chest compressions with the LUCAS™ device in cardiopulmonary resuscitation.

    abstract:AIM:The LUCAS™ device has been shown to improve organ perfusion during cardiac arrest in experimental studies. In this pilot study the aim was to compare short-term survival between cardiopulmonary resuscitation (CPR) performed with mechanical chest compressions using the LUCAS™ device and CPR performed with manual che...


    pub_type: 杂志文章,随机对照试验


    authors: Smekal D,Johansson J,Huzevka T,Rubertsson S

    更新日期:2011-06-01 00:00:00

  • From agonal to output: An ECG history of a successful pre-hospital thoracotomy.

    abstract::This case report describes the first reported successful UK pre-hospital thoracotomy performed outside the London HEMS system. Continuous ECG monitoring during the procedure has allowed presentation of sequential ECGs recorded during the procedure. ...


    pub_type: 杂志文章


    authors: Deakin CD

    更新日期:2007-12-01 00:00:00

  • Early- versus late-initiation of therapeutic hypothermia after cardiac arrest: preliminary observations from the experience of 17 Italian intensive care units.

    abstract:OBJECTIVES:Mild therapeutic hypothermia (TH) has been shown to improve neurologic outcome in patients experiencing cardiac arrest after return of spontaneous circulation (ROSC). The best timing to initiate TH is currently not known. The aim of this study by the ICE (Italian Cooling Experience) group was to investigate ...


    pub_type: 杂志文章


    authors: Italian Cooling Experience (ICE) Study Group.

    更新日期:2012-07-01 00:00:00

  • Lidocaine in out-of-hospital ventricular fibrillation. Does it improve survival?

    abstract:BACKGROUND:A large proportion of cardiac arrests outside hospital are caused by ventricular fibrillation. Although it is frequently used, the exact role for treatment with lidocaine in these patients remains to be determined. AIM:To describe the proportion of patients with witnessed out-of-hospital cardiac arrest foun...


    pub_type: 杂志文章


    authors: Herlitz J,Ekström L,Wennerblom B,Axelsson A,Bång A,Lindkvist J,Persson NG,Holmberg S

    更新日期:1997-01-01 00:00:00

  • Macrophage-specific protein perforin-2 is associated with poor neurological recovery and reduced survival after sudden cardiac arrest.

    abstract:BACKGROUND:Biomarkers involved in inflammation and stress response were implicated in patients who were successfully resuscitated from out of hospital cardiac arrest (sR-OHCA). Here we report that macrophage-expressed gene, perforin-2, an evolutionarily conserved protein with membrane attack domain, is associated with ...


    pub_type: 杂志文章


    authors: Kattel S,Bhatt H,Xu S,Gurung S,Pokharel S,Sharma UC

    更新日期:2020-10-01 00:00:00

  • Epinephrine in children receiving cardiopulmonary resuscitation for bradycardia with poor perfusion.

    abstract:AIM:To determine whether the use of epinephrine in pediatric patients receiving cardiopulmonary resuscitation for bradycardia and poor perfusion was associated with improved clinical outcomes. METHODS:Using the Get With The Guidelines-Resuscitation registry, we included pediatric patients (≤18 years) who received in-h...


    pub_type: 杂志文章


    authors: Holmberg MJ,Ross CE,Yankama T,Roberts JS,Andersen LW,American Heart Association’s Get With The Guidelines®-Resuscitation Investigators.

    更新日期:2020-04-01 00:00:00

  • Continuous cardiac index monitoring: A prospective observational study of agreement between a pulmonary artery catheter and a calibrated minimally invasive technique.

    abstract:INTRODUCTION:Continuous cardiac index (CCI) monitoring can provide information to assist in hemodynamic support. However, pulmonary artery catheters (PAC) pose logistic challenges in acute care settings. We hypothesized that CCI measured with a calibrated minimally invasive technique (LiDCO/PulseCO, UK) would have good...


    pub_type: 杂志文章


    authors: McCoy JV,Hollenberg SM,Dellinger RP,Arnold RC,Ruoss L,Lotano V,Peters P,Parrillo JE,Trzeciak S

    更新日期:2009-08-01 00:00:00

  • cDNA array analysis of gene expression following hemorrhagic shock and resuscitation in rats.

    abstract:UNLABELLED:The aim of this study was to characterize gene expression following hemorrhagic shock and resuscitation with emphasis on the differences between various resuscitation strategies. METHODS:Male Sprague Dawley rats (n = 25; 5/group) were subjected to a three stage hemorrhage and resuscitated as follows: (1) sh...


    pub_type: 杂志文章


    authors: Alam HB,Stegalkina S,Rhee P,Koustova E

    更新日期:2002-08-01 00:00:00

  • Pulseless electrical activity with witnessed arrest as a predictor of sudden death from massive pulmonary embolism in outpatients.

    abstract:BACKGROUND:the objective was to determine clinical characteristics that can quickly distinguish sudden death from massive pulmonary embolism (MPE) from other causes of sudden death. METHODS AND RESULTS:all medical examiner reports from Charlotte, NC from 1992 to 1999 (n=4926) were hand-searched for cases of sudden dea...


    pub_type: 杂志文章


    authors: Courtney DM,Sasser HC,Pincus CL,Kline JA

    更新日期:2001-06-01 00:00:00

  • Impact of the direct transfer to percutaneous coronary intervention-capable hospitals on survival to hospital discharge for patients with out-of-hospital cardiac arrest.

    abstract:AIMS:Patients suffering from out-of-hospital cardiac arrest (OHCA) are frequently transported to the closest hospital. Percutaneous coronary intervention (PCI) is often indicated following OHCA. This study's primary objective was to determine the association between being transported to a PCI-capable hospital and survi...


    pub_type: 杂志文章


    authors: Cournoyer A,Notebaert É,de Montigny L,Ross D,Cossette S,Londei-Leduc L,Iseppon M,Lamarche Y,Sokoloff C,Potter BJ,Vadeboncoeur A,Larose D,Morris J,Daoust R,Chauny JM,Piette É,Paquet J,Cavayas YA,de Champlain F,Segal

    更新日期:2018-04-01 00:00:00

  • Post resuscitation care: what are the therapeutic alternatives and what do we know?

    abstract::A large proportion of deaths in the Western World are caused by ischaemic heart disease. Among these patients a majority die outside hospital due to sudden cardiac death. The prognosis among these patients is in general, poor. However, a significant proportion are admitted to a hospital ward alive. The proportion of p...


    pub_type: 杂志文章,评审


    authors: Herlitz J,Castren M,Friberg H,Nolan J,Skrifvars M,Sunde K,Steen PA

    更新日期:2006-04-01 00:00:00

  • The effect of severe acute respiratory syndrome (SARS) on emergency airway management.

    abstract::From early March 2003 to late May 2003, severe acute respiratory syndrome (SARS) was detected in Singapore. The increase in workload and new infection control procedures were thought to affect resuscitation and airway management. Our aim was to study the effects of wearing of personal protective equipment (PPE) and po...


    pub_type: 杂志文章


    authors: Wong E,Ho KK

    更新日期:2006-07-01 00:00:00

  • Prediction of cognitive outcome based on the progression of auditory discrimination during coma.

    abstract:AIM:To date, no clinical test is able to predict cognitive and functional outcome of cardiac arrest survivors. Improvement of auditory discrimination in acute coma indicates survival with high specificity. Whether the degree of this improvement is indicative of recovery remains unknown. Here we investigated if progress...


    pub_type: 杂志文章


    authors: Juan E,De Lucia M,Tzovara A,Beaud V,Oddo M,Clarke S,Rossetti AO

    更新日期:2016-09-01 00:00:00

  • Cangrelor in cardiogenic shock and after cardiopulmonary resuscitation: A global, multicenter, matched pair analysis with oral P2Y12 inhibition from the IABP-SHOCK II trial.

    abstract:AIMS:Cangrelor has a potentially favorable pharmacodynamic profile in cardiogenic shock (CS). We aimed to evaluate the clinical course of CS patients undergoing percutaneous coronary intervention (PCI) treated with cangrelor. METHODS AND RESULTS:We retrospectively identified 136 CS patients treated with cangrelor. Pat...


    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Droppa M,Vaduganathan M,Venkateswaran RV,Singh A,Szumita PM,Roberts RJ,Qamar A,Hack L,Rath D,Gawaz M,Fuernau G,de Waha-Thiele S,Desch S,Schneider S,Ouarrak T,Jaffer FA,Zeymer U,Thiele H,Bhatt DL,Geisler T

    更新日期:2019-04-01 00:00:00