Abstract:
OBJECTIVES:An internet survey was performed to obtain data on the current use in Belgium of hormone replacement therapy and alternative treatments for the alleviation of menopausal symptoms. A supplementary aim was to assess the use of opt-in internet opinion panels (TalkToChange, http://www.talktochange.com, and GMI, http://www.gmi-mr.com/global-panel) as a potential new way to obtain data on menopausal issues. STUDY DESIGN:Data were collected via an internet platform from 696 postmenopausal women aged 45-60 years. OUTCOME MEASURES:Respondents were asked questions about their socio-demographic profile, their experience of the menopause, the burden of the menopause, its impact on their quality of life and the treatment of menopausal symptoms (if any). RESULTS:The opt-in internet opinion panels proved a quick way (19days) to obtain reliable information with a low error margin (3.7%). The online survey collected detailed socio-demographic data. Almost all of the women (98%) had heard about the menopause before. Sixty-one percent perceived the menopause as a temporary phase (17% thought it lasted for one or two years and 44% thought it lasted for three to five years) and only 39% realized the menopause would last for the rest of their life. Twenty-three percent of the women reported any kind of impact of the menopause on their quality of life. However, for the other 77% the menopause had resulted in complaints. No differences according to the women's age, level of education or professional status were found in this respect. Sixty-nine percent of the women had 'ever' used some type of treatment for menopausal symptoms and 53% were currently using a treatment. Forty percent of those with more than three symptoms were currently untreated. Of those who were not on hormone replacement therapy (HRT), 61% would not consider taking it (54% were 'strongly opposed' and 7% simply 'opposed'), while 8% would consider asking their doctor for HRT. Among those women who were opposed to HRT, 25% indicated that they were afraid of the increased risk of breast cancer, 34% cited cardiovascular risks and 26% were worried about weight gain. In this Belgian sample, HRT was used significantly more often by French-speaking women (32%) than by Dutch-speaking women (9%) (OR 4.4, p<0.0001). The alternatives to HRT had a high satisfaction rate among users. Relaxation techniques, regular physical activity, acupuncture and avoiding stress had satisfaction rates similar to that with HRT. It was not possible to compare the alternatives in the same women. Nor was it possible to assess whether more pronounced symptoms required a specific treatment. CONCLUSION:Opt-in internet opinion panels proved a quick and efficient way to gather data on menopausal issues in Belgium. Despite the high levels of awareness and knowledge, there is some confusion concerning the duration of the menopause, and its common perception as a temporary condition is likely to mean that the menopausal burden is substantially underestimated. Many symptomatic women are untreated.
journal_name
Maturitasjournal_title
Maturitasauthors
Depypere H,Pintiaux A,Desreux J,Hendrickx M,Neven P,Marchowicz E,Albert V,Leclercq V,Van den Branden S,Rozenberg Sdoi
10.1016/j.maturitas.2016.04.018subject
Has Abstractpub_date
2016-08-01 00:00:00pages
24-30eissn
0378-5122issn
1873-4111pii
S0378-5122(16)30097-4journal_volume
90pub_type
杂志文章相关文献
MATURITAS文献大全abstract::Androgen insensitivity syndrome (AIS) is one of the most common sexual developmental disorders. According to the grade of the remaining androgen receptor (AR) function, AIS is classified as complete (CAIS), partial (PAIS) or mild (MAIS). In CAIS, the prevalence of germ cell tumours is increased compared with the gener...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2019.06.004
更新日期:2019-09-01 00:00:00
abstract::Hormone replacement therapy (HRT) in postmenopausal women is associated with a reduction in the risk of developing coronary artery disease (CAD) of about 50%. Women with an elevated risk for CAD appear to benefit most by HRT. The HRT-associated cardiovascular protection may be related to favourable changes in several ...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/s0378-5122(98)00056-5
更新日期:1998-09-20 00:00:00
abstract::The explanations so far proposed for the effects of oestrogens on bone metabolism in post-menopausal women have been based on the changes seen in calciotrophic hormones. However, we demonstrated in a previous study [6] that there is a decrease in the concentration of somatomedin (an insulin-like growth factor) and an ...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/0378-5122(86)90002-2
更新日期:1986-03-01 00:00:00
abstract:INTRODUCTION:The use of menopausal hormone therapy (MHT) has decreased in many countries in the past 10 years. This is a consequence of the initial publication of the results of the Women's Health Initiative (WHI) randomized trial of estrogen plus progestin. In various countries, further studies then analyzed the incid...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2015.11.010
更新日期:2016-02-01 00:00:00
abstract::Gynaecologists have been criticized in recent years because of their attitude towards hysterectomy; it is often stated that they are too ready to consider hysterectomy to be indicated and that hysterectomies are carried out too frequently. In order to obtain insight into the incidence of hysterectomy, 2066 women betwe...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/0378-5122(83)90001-4
更新日期:1983-08-01 00:00:00
abstract::The extension of life expectancy is a global phenomenon. The growth in the ageing population has created a new health scenario in which there is a higher prevalence of frailty and multimorbidity. The attention received by both conditions derives from their strong association with disability, hospitalization, and death...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2016.10.008
更新日期:2017-01-01 00:00:00
abstract::Bone and muscle are required for mobility but they also have endocrine and metabolic functions. In ageing as well as in many chronic diseases, bone loss and muscle atrophy occur simultaneously, leading to concomitant osteoporosis and sarcopenia. This occurs in both genders but compared with postmenopausal women, men a...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2019.01.006
更新日期:2019-04-01 00:00:00
abstract::Stroke represents one of the most important menaces to public health. A number of modifiable and non-modifiable risk factors have been identified and studied in detail; among those, obesity, the new world epidemic, seems to be one of the most important in terms of prevention. The discovery of the secretory role of the...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2011.09.002
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVES:To establish dose proportionality among four doses of a new estradiol transdermal system (ETS), Estradot, in healthy postmenopausal women and to evaluate the wear and irritation properties of the ETS. METHODS:In an open label, single-dose, randomized, four-period crossover study, healthy postmenopausal wome...
journal_title:Maturitas
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0378-5122(03)00189-0
更新日期:2003-11-20 00:00:00
abstract::Heart disease is a major cause of death, disease and disability in the developed world for both men and women. Women appear to be under-diagnosed and treated both because they fail to visit the doctor or hospital with relevant symptoms and because doctors tend to dismiss the seriousness of women's symptoms of heart di...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2009.11.019
更新日期:2010-03-01 00:00:00
abstract::In direct contrast to the observational studies, both primary and secondary prevention trials of female reproductive hormones have found no benefit for coronary heart disease (CHD). Basic science studies have elucidated several mechanisms by which estrogen may improve coronary arterial physiology and prevent pathology...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2005.02.015
更新日期:2005-05-16 00:00:00
abstract:BACKGROUND:Quality of life decreases after the menopause as it has been assessed by several designed tools. Despite this, few studies have reported correlations between quality of life and the metabolic syndrome and its determinants. OBJECTIVE:Evaluate quality of life and determine factors related to its impairment am...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2006.05.008
更新日期:2007-01-20 00:00:00
abstract:OBJECTIVE:Social support interventions for caregivers of persons with dementia (PwD) are important because informal carers often rely on their social networks for support. This systematic review synthesises findings from research on social support interventions, and examines their methodological quality and effectivene...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2015.12.008
更新日期:2016-03-01 00:00:00
abstract::We designed a randomized double-blind randomized trial to examine the short and long-term effects of alternative approaches commonly used to manage menopause symptoms. Women were randomly assigned to: (1) black cohosh 160 mg daily; (2) multibotanical (50 mg black cohosh, alfalfa, chaste tree, dong quai, false unicorn,...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2008.11.014
更新日期:2008-09-01 00:00:00
abstract::The effect of estradiol valerate (Progynova, 2 mg daily) on the renin--aldosterone system was studied in nine women after bilateral oophorectomy. Plasma renin activity (PRA) and the daily urinary excretion of aldosterone (dU-Ald) were determined 4 mth after the operation -- during which no estrogen was given -- and af...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/0378-5122(80)90041-9
更新日期:1980-07-01 00:00:00
abstract::In the present study, we report on an additive evaluation of mental well-being in an established program of preventive medicine including general and gynecologic examination, and screening mammography. An easy-to-use questionnaire including 19 questions was completed by 5247 women. Answers were grouped into mental wel...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/s0378-5122(02)00010-5
更新日期:2002-04-15 00:00:00
abstract:OBJECTIVES:To examine Chinese middle-aged women's health and wellbeing and the associated biosocial correlates. STUDY DESIGN:This study used a cross-sectional design, including selected retrospectively collected information on the final menstrual period, drawn from the 2013 wave of the China Health and Retirement Long...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2020.10.008
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVES:Our pilot study tested the efficacy, acceptability and tolerability of DHA supplementation in addition to calcium and vitamin D in individuals with osteopenia. STUDY DESIGN:40 participants were randomised to either algal oil containing 400mg docosahexanoic acid (DHA) daily or placebo. All participants recei...
journal_title:Maturitas
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.maturitas.2011.10.004
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:To compare the influence on lipid metabolism of two discontinuous, sequentially combined hormone replacement therapy (HRT) regimens. STUDY DESIGN:In an open, randomized study in 60 women, a full lipid profile including Lp(a) and liver function tests were assessed in a fasting state at the end of treatment cy...
journal_title:Maturitas
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0378-5122(95)00920-g
更新日期:1995-09-01 00:00:00
abstract:OBJECTIVES:Over the past decade, dietary choices and nutrition have proven to be major modulators of bone mineral density (BMD) in men and women. We investigated environmental determinants, specifically dietary habits, of BMD by using multiple regression models in a rural Chinese population. METHODS:BMDs were measured...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2006.05.001
更新日期:2007-01-20 00:00:00
abstract:OBJECTIVE:To assess predictors of sexual function in mid-aged women. METHODS:We analyzed data of 262 healthy sexually active women (40-59 years) who filled out the Female Sexual Functioning Index (FSFI), the Menopause Rating Scale (MRS) and a general questionnaire containing female/partner data. Correlations between t...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2010.12.004
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:We investigated, using color Doppler ultrasound, possible detectable blood changes of prolonged treatment with 17-beta-estradiol tablets on uterine artery blood flow, in a cohort of low risk postmenopausal women. METHODS:39 postmenopausal women, who were taking local estrogen therapy for at least 6 months, w...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2004.07.004
更新日期:2005-04-11 00:00:00
abstract::The secretory endometrial protein PP14 was measured in serum from 49 healthy, early post-menopausal women receiving continuous combined oestradiol valerate/cyproterone acetate (2 mg E2V + 1 mg CPA daily) or placebo over a period of 2 years. In the hormone group, serum PP14 increased from 2.1 micrograms/l to a maximum ...
journal_title:Maturitas
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0378-5122(92)90060-h
更新日期:1992-08-01 00:00:00
abstract::While the benefits of progestins in hormonal replacement therapy are well recognized as far as endometrial protection is concerned the data on breast tissue and the cardiovascular system are contentious. Following the Women's Health Initiative study, the Million Women Study and The Women's International Study of Long-...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2008.12.019
更新日期:2009-04-20 00:00:00
abstract::Insomnia, vasomotor symptoms (VMS) and depression often co-occur after the menopause, with consequent health problems and reductions in quality of life. The aim of this position statement is to provide evidence-based advice on the management of postmenopausal sleep disorders derived from a systematic review of the lit...
journal_title:Maturitas
pub_type: 杂志文章,实务指引
doi:10.1016/j.maturitas.2019.08.006
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVES:This study examined factors associated with self-reported physical and mental health, focusing on caregiving status and the availability of social supports and financial resources. METHODS:Two bivariate analyses were performed to examine the sociodemographic characteristics as well as perceived health outco...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2011.10.011
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVES:The present experiment examined the role of age and fall history in upper body accelerations when walking on an even and on an uneven surface. STUDY DESIGN:An observational cross-sectional study. MAIN OUTCOME MEASURES:The magnitude (root mean square [RMS]), symmetry (harmonic ratio) and attenuation (attenu...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2020.05.016
更新日期:2020-09-01 00:00:00
abstract::Estrogen is a well-known mitogen in human breast epithelium but the action of progestogen is complex and incompletely understood. During the last years, accumulating data from animal, clinical and observational studies suggest a proliferative effect in breast tissue when progestogen is added to estrogen. Findings in s...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2004.06.008
更新日期:2004-09-24 00:00:00
abstract::Tibolone appears to be at least as efficacious as other forms of hormonal replacement therapy (HRT) on climacteric symptoms. It does not cause withdrawal bleeding when used in women with at least 1 year of amenorrhea. It is, therefore, not indicated in perimenopause because it may cause irregular bleeding. The androge...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/s0378-5122(98)00059-0
更新日期:1998-11-16 00:00:00
abstract:INTRODUCTION:The complexity of care required by many older people living in long-term care (LTC) facilities poses challenges that can lead to potentially avoidable referrals to a hospital emergency department (ED). The Aged Residential Care Intervention Project (ARCHIP) ran an implementation study to evaluate a multidi...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2018.08.014
更新日期:2018-11-01 00:00:00