Connecting laboratory behavior to field function through stable isotope analysis.

abstract：:Twist1, a basic helix-loop-helix transcription factor that regulates a number of genes involved in epithelial-to-mesenchymal transition (EMT), is upregulated in prostate cancer. Androgen regulation of Twist1 has been reported in a previous study. However, the mechanism of androgen regulation of the Twist1 gene is not ...

journal_title：PeerJ

authors： Khatiwada P,Kannan A,Malla M,Dreier M,Shemshedini L

更新日期：2020-04-09 00:00:00

abstract：Background:Dry eye disease (DED), a chronic ocular disease, is associated with numerous medical issues, including asthma. However, studies on these associations are limited. In this study, we investigated the incidence of DED among patients with asthma and its correlation with other allergic comorbidities. Methods:We ...

journal_title：PeerJ

authors： Huang YC,Chan WC,Wang JD,Fu LS,Tsan YT

更新日期：2018-12-05 00:00:00

abstract：:Background. Eucryptodiran turtles from the Late Jurassic (mainly Kimmeridgian) deposits of the Jura Mountains (Switzerland and France) are among the earliest named species traditionally referred to the Plesiochelyidae, Thalassemydidae, and Eurysternidae. As such, they are a reference for the study of Late Jurassic euc...

journal_title：PeerJ

authors： Anquetin J,Püntener C,Billon-Bruyat JP

更新日期：2014-05-13 00:00:00

abstract：:Following a radiation incident, preliminary dose estimates made by γ-H2AX foci analysis can supplement the early triage of casualties based on clinical symptoms. Sample processing time is important when many individuals need to be rapidly assessed. A protocol was therefore developed for high sample throughput that req...

journal_title：PeerJ

authors： Moquet J,Barnard S,Rothkamm K

更新日期：2014-03-06 00:00:00

abstract：:We present a semi-empirical (PM6-based) computational method for systematically estimating the effect of all possible single mutants, within a certain radius of the active site, on the barrier height of an enzymatic reaction. The intent of this method is not a quantitative prediction of the barrier heights, but rather...

journal_title：PeerJ

authors： Hediger MR,Steinmann C,De Vico L,Jensen JH

更新日期：2013-07-23 00:00:00

abstract：:In humans and apes, yawn contagion echoes emotional contagion, the basal layer of empathy. Hence, yawn contagion is a unique tool to compare empathy across species. If humans are the most empathic animal species, they should show the highest empathic response also at the level of emotional contagion. We gathered data ...

journal_title：PeerJ

authors： Palagi E,Norscia I,Demuru E

更新日期：2014-08-12 00:00:00

abstract：:The maximum likelihood estimation (MLE) method, typically used for polytomous logistic regression, is prone to bias due to both misclassification in outcome and contamination in the design matrix. Hence, robust estimators are needed. In this study, we propose such a method for nominal response data with continuous cov...

journal_title：PeerJ

authors： Wang X

更新日期：2014-07-01 00:00:00

abstract：Background:Nurses are often the first to activate the chain of survival when a cardiorespiratory arrest happens. That is why it is crucial that they keep their knowledge and skills up-to-date and their attitudes to resuscitation are very important. The main aim of this study was to analyse whether the level of theoreti...

journal_title：PeerJ

authors： Tíscar-González V,Blanco-Blanco J,Gea-Sánchez M,Rodriguez Molinuevo A,Moreno-Casbas T

更新日期：2019-02-07 00:00:00

abstract：:Closed cerebral hemorrhage (CCH) is a common symptom in traumatic brain injury (TBI) patients who suffer intracranial hemorrhage with the dura mater remaining intact. The diagnosis of CCH patients prior to hospitalization and in the early stage of the disease can help patients get earlier treatments that improve outco...

journal_title：PeerJ

authors： Yang J,Zhao H,Li G,Ran Q,Chen J,Bai Z,Jin G,Sun J,Xu J,Qin M,Chen M

更新日期：2019-04-12 00:00:00

abstract：:A new species of the genus Mesacanthion Filipjev, 1927 was discovered during a survey of natural beaches of Jeju Island in South Korea. The new species Mesacanthion jejuensissp. nov. shares general morphology of the genus such as the outer labial and cephalic setae being situated at the middle of cephalic capsule, wel...

journal_title：PeerJ

authors： Jeong R,Tchesunov AV,Lee W

更新日期：2019-11-18 00:00:00

abstract：:Abnormal behaviors in captive animals are generally defined as behaviors that are atypical for the species and are often considered to be indicators of poor welfare. Although some abnormal behaviors have been empirically linked to conditions related to elevated stress and compromised welfare in primates, others have l...

journal_title：PeerJ

authors： Jacobson SL,Ross SR,Bloomsmith MA

更新日期：2016-07-13 00:00:00

abstract：:There has been an increase in the mortality rate and morbidity of kidney cancer (KC) with kidney renal clear cell carcinoma (KIRC) being the most common subtype of KC. GRAMD1C (GRAM Domain Containing 1C) has not been reported to relate to prognosis and immunotherapy in any cancers. Using bioinformatics methods, we jud...

journal_title：PeerJ

authors： Hao H,Wang Z,Ren S,Shen H,Xian H,Ge W,Wang W

更新日期：2019-12-20 00:00:00

abstract：Background:Begomoviruses are widely distributed and causing devastating diseases in many crops. According to the number of genomic components, a begomovirus is known as either monopartite or bipartite begomovirus. Both the monopartite and bipartite begomoviruses have the DNA-A component which encodes all essential prot...

journal_title：PeerJ

authors： Pei S,Dong R,Bao Y,He RL,Yau SS

更新日期：2020-08-03 00:00:00

abstract：:China has experienced intensive urbanization over the past decades. However, it is still unclear about the influence of urbanization on urban thermal comfort and how the effect varies with climate condition. Based on long-term daily meteorological data from 1990 to 2015 in four Chinese cities undergoing rapid urbaniza...

journal_title：PeerJ

authors： Fu Y,Ren Z,Yu Q,He X,Xiao L,Wang Q,Liu C

更新日期：2019-11-11 00:00:00

abstract：:Trypophobia is a strong emotion of disgust evoked by clusters of holes or round objects (e.g., lotus seed pod). It has become increasingly popular and been studied since 2010s, mainly in the West and Japan. Considering this, trypophobia might be a modern emotion, and hence urbanization possibly plays key roles in tryp...

journal_title：PeerJ

authors： Zhu S,Sasaki K,Jiang Y,Qian K,Yamada Y

更新日期：2020-03-18 00:00:00

abstract：:The Yazoo Darter, Etheostoma raneyi (Percidae), is an imperiled freshwater fish species endemic to tributaries of the Yocona and Little Tallahatchie rivers of the upper Yazoo River basin, in northern Mississippi, USA. The two populations are allopatric, isolated by unsuitable lowland habitat between the two river drai...

journal_title：PeerJ

authors： Sterling KA,Nielsen SV,Brown AJ,Warren ML Jr,Noonan BP

更新日期：2020-05-04 00:00:00

abstract：:Rao's quadratic diversity index is one of the most widely applied diversity indices in functional and phylogenetic ecology. The standard way of computing Rao's quadratic diversity index for an ecological assemblage with a group of species with varying abundances is to sum the functional or phylogenetic distances betwe...

journal_title：PeerJ

authors： Chen Y,Wu Y,Shen TJ

更新日期：2018-07-06 00:00:00

abstract：Background:Large and complex mounds built by termites of the genus Macrotermes characterize many dry African landscapes, including the savannas, bushlands, and dry forests of the Tsavo Ecosystem in southern Kenya. The termites live in obligate symbiosis with filamentous fungi of the genus Termitomyces. The insects coll...

journal_title：PeerJ

authors： Vesala R,Harjuntausta A,Hakkarainen A,Rönnholm P,Pellikka P,Rikkinen J

更新日期：2019-01-16 00:00:00

abstract：:Background. The relative efficacy and safety of lacosamide as adjunctive therapy compared to other antiepileptic drugs has not been well established. Objective. To determine if lacosamide provides improved efficacy and safety, reduced length of hospital stay and improved quality of life compared with other anti-epilep...

journal_title：PeerJ

authors： Sawh SC,Newman JJ,Deshpande S,Jones PM

更新日期：2013-08-06 00:00:00

abstract：Background:The highest rate of cancer-related deaths worldwide is from lung adenocarcinoma (LUAD) annually. Metabolism was associated with tumorigenesis and cancer development. Metabolic-related genes may be important biomarkers and metabolic therapeutic targets for LUAD. Materials and Methods:In this study, the glean...

journal_title：PeerJ

authors： Zhao Z,He B,Cai Q,Zhang P,Peng X,Zhang Y,Xie H,Wang X

更新日期：2020-09-24 00:00:00

abstract：Background:Extensive genome rearrangements, known as chromothripsis, have been recently identified in several cancer types. Chromothripsis leads to complex structural variants (cSVs) causing aberrant gene expression and the formation of de novo fusion genes, which can trigger cancer development, or worsen its clinical ...

journal_title：PeerJ

authors： Hynst J,Plevova K,Radova L,Bystry V,Pal K,Pospisilova S

更新日期：2019-06-12 00:00:00

abstract：:Type I restriction-modification enzymes are multisubunit, multifunctional molecular machines that recognize specific DNA target sequences, and their multisubunit organization underlies their multifunctionality. EcoR124I is the archetype of Type I restriction-modification family IC and is composed of three subunit type...

journal_title：PeerJ

authors： Bialevich V,Sinha D,Shamayeva K,Guzanova A,Řeha D,Csefalvay E,Carey J,Weiserova M,Ettrich RH

更新日期：2017-01-18 00:00:00

abstract：:Seabed mapping can quantify the extent of benthic habitats that comprise marine ecosystems, and assess the impact of fisheries on an ecosystem. In this study, the distribution of seabed habitats in a proposed no-take Marine Reserve along the northeast coast of Great Barrier Island, New Zealand, was mapped using underw...

journal_title：PeerJ

authors： Lee ST,Kelly M,Langlois TJ,Costello MJ

更新日期：2015-12-10 00:00:00

abstract：Background:Reward seeking and avoidance of punishment are key motivational processes. Brain-imaging studies often use the Monetary Incentive Delay Task (MIDT) to evaluate motivational processes involved in maladaptive behavior. Although the bulk of research has been done on the MIDT reward events, little is known about...

journal_title：PeerJ

authors： Dugré JR,Dumais A,Bitar N,Potvin S

更新日期：2018-05-10 00:00:00

abstract：BACKGROUND:Preterm birth is a main determinant of neonatal mortality and morbidity and a major contributor to the overall mortality and burden of disease. However, research of the preterm birth is hindered by the imprecise definition of the clinical phenotype and complexity of the molecular phenotype due to multiple pr...

journal_title：PeerJ

authors： Bukowski R,Sadovsky Y,Goodarzi H,Zhang H,Biggio JR,Varner M,Parry S,Xiao F,Esplin SM,Andrews W,Saade GR,Ilekis JV,Reddy UM,Baldwin DA

更新日期：2017-09-01 00:00:00

abstract：:Weaning is an important event for all mammals, including young forest musk deer. However, weaning stress may cause intestinal microbiota-related disorders. Therefore, high-throughput 16S rRNA gene sequencing was applied to study the dynamic changes in intestinal microbiota during pre-weaning (10 days before weaning) a...

journal_title：PeerJ

authors： Li Y,Shi M,Zhang T,Hu X,Zhang B,Xu S,Ding J,Hu D,Liu S

更新日期：2020-04-13 00:00:00

abstract：Background:Experiencing an adequate amount of cold temperatures over winter is necessary for many temperate tree species to break dormancy and flower in spring. Thus, changes in winter and spring temperatures associated with climate change may influence when trees break dormancy and flower in the future. There have bee...

journal_title：PeerJ

authors： Prevéy JS,Harrington CA

更新日期：2018-09-25 00:00:00

abstract：BACKGROUND:The human microbiota plays a key role in health and disease, and bacteriocins, which are small, bacterially produced, antimicrobial peptides, are likely to have an important function in the stability and dynamics of this community. Here we examined the density and distribution of the subclass I lantibiotic m...

journal_title：PeerJ

authors： Walsh CJ,Guinane CM,O' Toole PW,Cotter PD

更新日期：2017-04-27 00:00:00

abstract：:The spatial learning skills of high and low stress juvenile mulloway (Argyrosomus japonicus) were tested in a dichotomous choice apparatus. Groups of fish were formed based on background blood cortisol levels and required to learn the location of a food reward hidden in one of two compartments. Low stress fish charact...

journal_title：PeerJ

authors： Raoult V,Trompf L,Williamson JE,Brown C

更新日期：2017-06-08 00:00:00

abstract：:The fight against the emergence of mutant influenza strains has led to the screening of an increasing number of compounds for inhibitory activity against influenza neuraminidase. This study explores the chemical space of neuraminidase inhibitors (NAIs), which provides an opportunity to obtain further molecular insight...

journal_title：PeerJ

authors： Anuwongcharoen N,Shoombuatong W,Tantimongcolwat T,Prachayasittikul V,Nantasenamat C

更新日期：2016-04-19 00:00:00