当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES期刊下所有文献 > Synthesis and characterization of antibacterial carboxymethyl Chitosan/ZnO nanocomposite hydrogels.

Synthesis and characterization of antibacterial carboxymethyl Chitosan/ZnO nanocomposite hydrogels.

Abstract：

:The antibacterial carboxymethyl chitosan/ZnO nanocomposite hydrogels were successfully prepared via in situ formation of ZnO nanorods in the crosslinked carboxymethyl chitosan (CMCh) matrix, by treating the CMCh hydrogel matrix with zinc nitrate solution followed by the oxidation of zinc ions with alkaline solution. The resulting CMCh/ZnO hydrogels were characterized by using FTIR spectroscopy, X-ray diffractormetry and scanning electron microscopy (SEM). SEM micrographs revealed the formation of ZnO nanorods in the hydrogel matrix with the size ranging from 190nm to 600nm. The swelling behavior of the prepared nanocomposite hydrogels was also investigated in different pH solutions. The CMCh/ZnO nanocomposite hydrogel showed rather higher swelling behavior in different pH solutions in comparison with neat CMCh hydrogel. Furthermore, the antibacterial activity of CMCh/ZnO hydrogel was studied against Escherichia coli and Staphylococcus aureus by CFU assay. The results demonstrated an excellent antibacterial activity of the nanocomposite hydrogel. Therefore, the developed CMCh/ZnO nanocomposite hydrogel can be used effectively in biomedical field.

journal_name

Int J Biol Macromol

journal_title

International journal of biological macromolecules

authors

Wahid F,Yin JJ,Xue DD,Xue H,Lu YS,Zhong C,Chu LQ

doi

10.1016/j.ijbiomac.2016.03.044

subject

Has Abstract

pub_date

2016-07-01 00:00:00

pages

273-9

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(16)30268-9

journal_volume

88

pub_type

杂志文章

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