Abstract：
:Quercetin-3-O-rutinoside (rutin), quercetin-3-O-glucoside (isoquercetin) and quercetin have shown antioxidant, cytoprotective, vasoprotective, antiproliferative and antiinflammatory properties. The aim of this work was to determine the conversion of rutin to isoquercetin and quercetin during the production of poly(l-lactic acid) films with potential to deliver these flavonoids toward tissues, pharmaceuticals or food matrices. Three poly(l-lactic acid) formulations with 17.7, 39.6 and 39.1mg/g of rutin were prepared by the extrusion process. Processing temperatures (130-165°C) promoted the deglycosylation of rutin to produce isoquercetin and subsequently quercetin, identified by high performance liquid chromatography coupled to mass spectrometry. The effect of the process on the antioxidant activity of the films was determined by measuring the capacity to scavenge 2,2 diphenyl-1-picrylhydrazyl radicals. The material with the highest proportion of quercetin showed the highest antioxidant activity which could be used to produce delivering devices of the flavonoids to tissues, pharmaceuticals or food matrices.
journal_name
Food Chemjournal_title
Food chemistryauthors
Cruz-Zúñiga JM,Soto-Valdez H,Peralta E,Mendoza-Wilson AM,Robles-Burgueño MR,Auras R,Gámez-Meza Ndoi
10.1016/j.foodchem.2016.02.130subject
Has Abstractpub_date
2016-08-01 00:00:00pages
420-426eissn
0308-8146issn
1873-7072pii
S0308-8146(16)30299-0journal_volume
204pub_type
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