Abstract:
BACKGROUND:Physical activity has been hypothesized to reduce the risk of gallbladder disease (gallstones, cholecystitis, cholecystectomy); however, results from epidemiological studies have not always shown statistically significant associations. We conducted a systematic review and meta-analysis to clarify the presence and strength of an association between physical activity and gallbladder disease risk. METHODS:PubMed and Embase databases were searched for studies of physical activity and gallbladder disease up to 9th of January 2015. Prospective studies reporting relative risk (RR) estimates and 95% confidence intervals (CIs) of gallbladder disease associated with physical activity were included. Summary RRs were estimated using a random effects model. RESULTS:Eight studies including 6958 cases and 218,204 participants were included. The summary RR for the highest versus the lowest level of physical activity was 0.75 (95% CI: 0.69-0.81, n = 8) and there was no evidence of heterogeneity, I2 = 0%). In the dose-response analysis the summary relative risk per 20 MET-hours of activity was 0.85 (95% CI: 0.80-0.90, I2 = 0%, n = 2) for leisure-time physical activity, 0.83 (95% CI: 0.76-0.90, I2 = 0%, n = 2) for vigorous physical activity, and 0.86 (95% CI: 0.76-0.98, I2 = 0%, n = 2) for nonvigorous physical activity. CONCLUSION:Our analysis confirms a protective effect of physical activity on risk of gallbladder disease.
journal_name
J Phys Act Healthjournal_title
Journal of physical activity & healthauthors
Aune D,Leitzmann M,Vatten LJdoi
10.1123/jpah.2015-0456subject
Has Abstractpub_date
2016-07-01 00:00:00pages
788-95issue
7eissn
1543-3080issn
1543-5474pii
2015-0456journal_volume
13pub_type
杂志文章,meta分析,评审abstract:BACKGROUND:Self-efficacy can be affected by mastery experiences and somatic sensations. A novel exercise experience and associated sensations may impact self-efficacy and subsequent behaviors. We investigated the effect of a single exercise session on self-efficacy for sedentary endometrial cancer survivors compared wi...
journal_title:Journal of physical activity & health
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journal_title:Journal of physical activity & health
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journal_title:Journal of physical activity & health
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journal_title:Journal of physical activity & health
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pub_type: 杂志文章
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journal_title:Journal of physical activity & health
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journal_title:Journal of physical activity & health
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journal_title:Journal of physical activity & health
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doi:10.1123/jpah.6.2.137
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journal_title:Journal of physical activity & health
pub_type: 杂志文章
doi:10.1123/jpah.5.3.430
更新日期:2008-05-01 00:00:00
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journal_title:Journal of physical activity & health
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journal_title:Journal of physical activity & health
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journal_title:Journal of physical activity & health
pub_type: 杂志文章
doi:10.1123/jpah.2013-0125
更新日期:2014-11-01 00:00:00
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journal_title:Journal of physical activity & health
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journal_title:Journal of physical activity & health
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journal_title:Journal of physical activity & health
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journal_title:Journal of physical activity & health
pub_type: 杂志文章
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更新日期:2015-02-01 00:00:00
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journal_title:Journal of physical activity & health
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journal_title:Journal of physical activity & health
pub_type: 杂志文章
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journal_title:Journal of physical activity & health
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更新日期:2020-04-01 00:00:00
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journal_title:Journal of physical activity & health
pub_type: 杂志文章,评审
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journal_title:Journal of physical activity & health
pub_type: 杂志文章
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journal_title:Journal of physical activity & health
pub_type: 杂志文章
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