miR-27b attenuates apoptosis induced by transmissible gastroenteritis virus (TGEV) infection via targeting runt-related transcription factor 1 (RUNX1).

abstract：Background:Little is known regarding the toxic and therapeutic doses of amygdalin. Treatment regimens and schedules can vary between humans and animal models, and there have been reports of cyanide toxicity due to amygdalin use. Objective:The aim of this study was to evaluate the effect of different doses of amygdalin...

journal_title：PeerJ

authors： Albogami S,Hassan A,Ahmed N,Alnefaie A,Alattas A,Alquthami L,Alharbi A

更新日期：2020-05-21 00:00:00

abstract：Background:Circadian genes have been suggested to play an important role in lung pathology. However, it remains unknown whether polymorphisms of these genes are associated with chronic obstructive pulmonary disease (COPD). Here, we aimed to investigate the association of circadian genes polymorphisms with COPD in a cas...

journal_title：PeerJ

authors： Chen G,Zhang J,Zhang L,Xiong X,Yu D,Zhang Y

更新日期：2020-08-27 00:00:00

abstract：Aims:Periodontitis and psoriatic disease, including psoriasis (PS) and psoriatic arthritis (PsA), share the common risk factors and co-morbidities. However, the risk of periodontitis in patients with psoriatic disease still needs further investigation. This study was a nationwide population-based retrospective cohort s...

journal_title：PeerJ

authors： Su NY,Huang JY,Hu CJ,Yu HC,Chang YC

更新日期：2017-11-16 00:00:00

abstract：:A new species of Scutalus Albers, 1850 (Gastropoda: Bulimulidae), Scutalus chango sp. n., is described from a coastal area of northern Chile. Empty shells of this new species were found buried in sand and under boulders and rocks in the foothills of the Chilean Coastal Range at Paposo, Región de Antofagasta. This new ...

journal_title：PeerJ

authors： Araya JF,Breure ASH

更新日期：2017-07-05 00:00:00

abstract：:At the turn of February and March 2020, COVID-19 pandemic reached Europe. Many countries, including Poland imposed lockdown as a method of securing social distance between potentially infected. Stay-at-home orders and movement control within public space not only affected the touristm industry, but also the everyday l...

journal_title：PeerJ

authors： Szczepanek R

更新日期：2020-10-05 00:00:00

abstract：Background:The Aegean Sea coast of Turkey hosts one of the most important nesting grounds for loggerhead sea turtles (Caretta caretta) in the Mediterranean Sea. Previous studies have revealed that the sea turtle carapace provides favourable conditions for various epibiontic organisms. Epibionts occurring on the carapac...

journal_title：PeerJ

authors： Kaleli A,Car A,Witkowski A,Krzywda M,Riaux-Gobin C,Solak CN,Kaska Y,Zgłobicka I,Płociński T,Wróbel R,Kurzydłowski K

更新日期：2020-07-17 00:00:00

abstract：:Seasonal upwelling at the northern Pacific coast of Costa Rica offers the opportunity to investigate the effects of pronounced changes in key water parameters on fine-scale dynamics of local coral reef communities. This study monitored benthic community composition at Matapalo reef (10.539°N, 85.766°W) by weekly obser...

journal_title：PeerJ

authors： Stuhldreier I,Sánchez-Noguera C,Roth F,Jiménez C,Rixen T,Cortés J,Wild C

更新日期：2015-11-24 00:00:00

abstract：:The currently-accepted dogma when analysing human Alu transposable elements is that 'young' Alu elements are found in low GC regions and 'old' Alus in high GC regions. The correlation between high GC regions and high gene frequency regions make this observation particularly difficult to explain. Although a number of s...

journal_title：PeerJ

authors： Hellen EH,Brookfield JF

更新日期：2013-05-21 00:00:00

abstract：:Background. Although the trot is described as a diagonal gait, contacts of the diagonal pairs of hooves are not usually perfectly synchronized. Although subtle, the timing dissociation between contacts of each diagonal pair could have consequences on gait dynamics and provide insight into the functional strategies emp...

journal_title：PeerJ

authors： Hobbs SJ,Bertram JE,Clayton HM

更新日期：2016-06-30 00:00:00

abstract：Background:Ecosystem engineers are species that transform habitats in ways that influence other species.While the impacts of many engineers have been well described, our understanding of how their impact varies along environmental gradients remains limited. Although disentangling the effects of gradients and engineers ...

journal_title：PeerJ

authors： Costa AN,Bruna EM,Vasconcelos HL

更新日期：2018-10-09 00:00:00

abstract：:Background. Blacklegged ticks (Ixodes scapularis) are important disease vectors in the United States, known to transmit a variety of pathogens to humans, including bacteria, protozoa, and viruses. Their importance as a disease vector necessitates reliable and comparable methods for extracting microbial DNA from ticks....

journal_title：PeerJ

authors： Ammazzalorso AD,Zolnik CP,Daniels TJ,Kolokotronis SO

更新日期：2015-08-13 00:00:00

abstract：Background:The independent effects of hypohydration and hyperthermia on cognition and mood is unclear since the two stresses often confound each other. Further, it is unknown if obese individuals have the same impairments during hyperthermia and hypohydration that is often observed in non-obese individuals. Methods:Th...

journal_title：PeerJ

authors： Caldwell AR,Burchfield J,Moyen NE,Tucker MA,Butts CL,Elbin RJ,Ganio MS

更新日期：2018-08-16 00:00:00

abstract：:Jatropha curcas L. belongs to Euphorbiaceae family, and it synthesizes flavonoid and diterpene compounds that have showed antioxidant, anti-inflammatory, anticancer, antiviral, antimicrobial, antifungal and insecticide activity. Seeds of this plant accumulate phorbol esters, which are tigliane type diterpenes, reporte...

journal_title：PeerJ

authors： Leyva-Padrón G,Vanegas-Espinoza PE,Evangelista-Lozano S,Del Villar-Martínez AA,Bazaldúa C

更新日期：2020-11-11 00:00:00

abstract：:Histopathological images contain rich phenotypic descriptions of the molecular processes underlying disease progression. Convolutional neural networks, state-of-the-art image analysis techniques in computer vision, automatically learn representative features from such images which can be useful for disease diagnosis, ...

journal_title：PeerJ

authors： Lu L,Daigle BJ Jr

更新日期：2020-03-12 00:00:00

abstract：:Mollusc shells are an abundant resource that have been long used to predict the structures of ancient ecological communities, examine evolutionary processes, reconstruct paleoenvironmental conditions, track and predict responses to climatic change, and explore the movement of hominids across the globe. Despite the ubi...

journal_title：PeerJ

authors： Ferreira S,Ashby R,Jeunen GJ,Rutherford K,Collins C,Todd EV,Gemmell NJ

更新日期：2020-07-30 00:00:00

abstract：:This study aimed to investigate the effects of Clostridium butyricum as a dietary probiotic supplement in fishmeal based diet on growth, gut microbiota and immune performance of marron (Cherax cainii). Marron were randomly distributed into two different treatment groups, control and probiotic fed group. After 42 days ...

journal_title：PeerJ

authors： Foysal MJ,Nguyen TTT,Chaklader MR,Siddik MAB,Tay CY,Fotedar R,Gupta SK

更新日期：2019-08-27 00:00:00

abstract：:Potential natural vegetation (PNV) is the vegetation cover in equilibrium with climate, that would exist at a given location if not impacted by human activities. PNV is useful for raising public awareness about land degradation and for estimating land potential. This paper presents results of assessing machine learnin...

journal_title：PeerJ

authors： Hengl T,Walsh MG,Sanderman J,Wheeler I,Harrison SP,Prentice IC

更新日期：2018-08-22 00:00:00

abstract：:Stridulatory signals are involved in conspecific interactions between bark beetles (Coleoptera: Curculionidae, Scolytinae). In this study, we compared the qualitative profiles of acoustic signals in three species from the genus Polygraphus Er. Sympatry can be periodically observed in two of them -P. proximus and P. su...

journal_title：PeerJ

authors： Kerchev IA

更新日期：2020-01-02 00:00:00

abstract：:Lead (Pb) is a ubiquitous pollutant which poses serious threats to plants, animals and humans once entered into the food chain via contaminated industrial effluents on their discharge into the surface of water bodies and/or geological materials. This study aimed to examine and compare the biosorption potential of natu...

journal_title：PeerJ

authors： Shah GM,Nasir M,Imran M,Bakhat HF,Rabbani F,Sajjad M,Umer Farooq AB,Ahmad S,Song L

更新日期：2018-09-28 00:00:00

abstract：Background:As key negative regulators of gene expression, microRNAs (miRNAs) play an important role in the onset and progression of hepatocellular carcinoma (HCC). This study aimed to identify the miRNAs involved in HCC carcinogenesis and their regulated genes. Methods:The Gene Expression Omnibus (GEO) dataset (GSE108...

journal_title：PeerJ

authors： Liu Y,Cao Y,Cai W,Wu L,Zhao P,Liu XG

更新日期：2020-04-29 00:00:00

abstract：:Lupus nephritis (LN) is a severe manifestation of systemic lupus erythematosus (SLE), which often progresses to end-stage renal disease (ESRD) and ultimately leads to death. At present, there are no definitive therapies towards LN, so that illuminating the molecular mechanism behind the disease has become an urgent ta...

journal_title：PeerJ

authors： Yang H,Li H

更新日期：2019-10-01 00:00:00

abstract：Background:In the absence of highly effective antiviral therapies against SARS-CoV-2, it is crucial to counter the known pathophysiological causes of severe COVID-19. Evaluating the efficacy existing drugs may expedite the development of such therapeutics. Severe COVID-19 is largely the result of a dysregulated immune ...

journal_title：PeerJ

authors： Kaye AG,Siegel R

更新日期：2020-11-02 00:00:00

abstract：:The aim of this study was to identify the facets influencing job satisfaction and intention to quit of nurses employed in Turkey. Using a non-probability sampling technique, 417 nurses from six large private hospitals were surveyed from March 2014 to June 2014. The nurses' demographic data, their job-related satisfact...

journal_title：PeerJ

authors： Masum AK,Azad MA,Hoque KE,Beh LS,Wanke P,Arslan Ö

更新日期：2016-04-26 00:00:00

abstract：:Histone deacetylases (HDACs) are key epigenetic factors in regulating chromatin structure and gene expression in multiple aspects of plant growth, development, and response to abiotic or biotic stresses. Many studies on systematic analysis and molecular function of HDACs in Arabidopsis and rice have been conducted. Ho...

journal_title：PeerJ

authors： Zhang K,Yu L,Pang X,Cao H,Si H,Zang J,Xing J,Dong J

更新日期：2020-02-12 00:00:00

abstract：:Diffuse sources of pollution like agricultural or urban runoff are important factors in determining the quality of surface waters, although they are more difficult to monitor than point sources. The objective of our study was to verify assumptions that the inflow from agricultural nutrient sources is higher than from ...

journal_title：PeerJ

authors： Matej-Lukowicz K,Wojciechowska E,Nawrot N,Dzierzbicka-Głowacka LA

更新日期：2020-02-06 00:00:00

abstract：:Loud calls are used by many species as long-distance signals for group defense, mate attraction, and inter- and intragroup spacing. Chimpanzee loud calls, or pant hoots, are used in a variety of contexts including group coordination and during male contests. Here, we observed an alpha male takeover in wild chimpanzees...

journal_title：PeerJ

authors： Kalan AK,Boesch C

更新日期：2018-06-28 00:00:00

abstract：:I used radio-telemetry to track the movements of Mangrove Cuckoos (Coccyzus minor) captured in southwest Florida. Relatively little is known about the natural history of Mangrove Cuckoos, and my goal was to provide an initial description of how individuals use space, with a focus on the size and placement of home rang...

journal_title：PeerJ

authors： Lloyd JD

更新日期：2017-06-30 00:00:00

abstract：:Protection of honey bees is of great economic importance because of their role in pollination. Crucial steps towards this goal are epidemiological surveys of pathogens connected with honey bee losses. In this study deformed wing virus (DWV), chronic bee paralysis virus (CBPV), acute bee paralysis virus (ABPV) and sacb...

journal_title：PeerJ

authors： Cirkovic D,Stevanovic J,Glavinic U,Aleksic N,Djuric S,Aleksic J,Stanimirovic Z

更新日期：2018-11-14 00:00:00

abstract：:Following a radiation incident, preliminary dose estimates made by γ-H2AX foci analysis can supplement the early triage of casualties based on clinical symptoms. Sample processing time is important when many individuals need to be rapidly assessed. A protocol was therefore developed for high sample throughput that req...

journal_title：PeerJ

authors： Moquet J,Barnard S,Rothkamm K

更新日期：2014-03-06 00:00:00

abstract：:N-Acetyl-p-Aminophenol (APAP), also known as acetaminophen, is the most commonly used over-the counter analgesic and antipyretic medication. However, its overdose leads to both liver and kidney damage. APAP-induced toxicity is considered as one of the primary causes of acute liver failure; numerous scientific reports ...

journal_title：PeerJ

authors： Karthivashan G,Kura AU,Arulselvan P,Md Isa N,Fakurazi S

更新日期：2016-07-07 00:00:00