Abstract:
BACKGROUND:Older patients, due to polypharmacy, co-morbidities and often multiple prescribing doctors are particularly susceptible to medication history errors, leading to adverse drug events, patient harm and increased costs. Medication reconciliation at the point of admission to hospital can reduce medication discrepancies and adverse events. The Structured HIstory taking of Medication use (SHiM) tool was developed to provide a structure to the medication reconciliation process. There has been very little research with regards to SHiM, it's application to older patients and it's potential to reduce adverse events. OBJECTIVE:To determine whether application of SHiM could optimise older patients' prescriptions on admission to hospital, and in-turn reduce adverse events, compared to standard care. SETTING:A sub-study of a large clinical trial involving hospital inpatients over the age of 65 in five hospitals across Europe. METHOD:A modified version of SHiM was used to obtain accurate drug histories for patients after the attending physician had obtained a medication list via standard methods. Discrepancies between the two lists were recorded and classified, and the clinical relevance of the discrepancies was determined. Whether discrepancies in patients' medication histories, as revealed by SHiM, resulted in actual clinical consequences was then investigated. As this study was carried out during the observation phase of the clinical trial, results were not communicated to the medical teams. MAIN OUTCOME MEASURE:Discrepancies between medication lists and whether these resulted in clinical consequences. RESULTS:SHiM was applied to 123 patients. The mean age of the participants was 78 (±6). 200 discrepancies were identified. 90 patients (73 %) had at least one discrepancy with a median of 1.0 discrepancies per patient (IQR 0.00-2.25). 53 (26.5 %) were classified as 'unlikely to cause patient discomfort or clinical deterioration', 145 (72.5 %) as 'having potential to cause moderate discomfort or clinical deterioration', and 2 (1 %) as 'having potential to cause severe discomfort or clinical deterioration'. Of the 200 discrepancies identified, 2(1 %) resulted in adverse events. CONCLUSION:The results suggest SHiM is an effective medications reconciliation tool and does identify discrepancies with potential for patient harm. However, it's the capacity to prevent actual adverse events is less convincing.
journal_name
Int J Clin Pharmjournal_title
International journal of clinical pharmacyauthors
Cullinan S,O'Mahony D,Byrne Sdoi
10.1007/s11096-016-0254-0subject
Has Abstractpub_date
2016-04-01 00:00:00pages
374-9issue
2eissn
2210-7703issn
2210-7711pii
10.1007/s11096-016-0254-0journal_volume
38pub_type
杂志文章,多中心研究,随机对照试验abstract::Background Medication discrepancies often occur at transition of care such as hospital admission and discharge. Obtaining a complete and accurate medication history on admission is essential as further treatment is based on it. Objective The goal of this study was to reduce the proportion of patients with at least one...
journal_title:International journal of clinical pharmacy
pub_type: 杂志文章
doi:10.1007/s11096-017-0545-0
更新日期:2017-12-01 00:00:00
abstract::The article Knowledge of cardiovascular disease risk factors and practice of primary prevention of cardiovascular disease by Community Pharmacists in Nigeria: a cross-sectional study. ...
journal_title:International journal of clinical pharmacy
pub_type: 已发布勘误
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abstract:BACKGROUND:Patient satisfaction is an important determinant of the feasibility and sustainability of community pharmacy screening services. However, few studies have evaluated this, with no such study performed for a chronic kidney disease risk assessment service. OBJECTIVE:The aim was to determine patient satisfactio...
journal_title:International journal of clinical pharmacy
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abstract::Background Chronic pain is a prevalent and debilitating condition for many people. Globally it is the greatest contributor to years lived with disability. Management often includes pharmacotherapy and pharmacists are therefore well placed to contribute to chronic pain management. Objective To explore chronic pain mana...
journal_title:International journal of clinical pharmacy
pub_type: 杂志文章
doi:10.1007/s11096-020-01198-8
更新日期:2020-11-27 00:00:00
abstract::It is widely acknowledged that patients-particularly those late in life-are frequently exposed to the harms of medication. To minimize these harms, several frameworks have been developed by which prescribing can be optimized. In the context of diminishing life expectancy, these frameworks can be used to reduce medicat...
journal_title:International journal of clinical pharmacy
pub_type: 杂志文章
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更新日期:2015-10-01 00:00:00
abstract::Background Allergic rhinitis represents a public health problem that is significantly prevalent in the global population and has been associated with asthma, a strong desire to sleep and a low quality of life. Objective This study aims to evaluate the prevalence, symptoms, control strategies and treatment, as well as ...
journal_title:International journal of clinical pharmacy
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doi:10.1007/s11096-020-01115-z
更新日期:2020-09-20 00:00:00
abstract::Background The challenges of under-reporting of adverse drug reactions have been identified as a major setback for the pharmacovigilance system worldwide. Direct reporting by health care consumers has been adopted in some developed and developing countries with a positive impact in improving pharmacovigilance activiti...
journal_title:International journal of clinical pharmacy
pub_type: 杂志文章,评审
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abstract::Background The management of multiple long-term medicines of patients with chronic diseases creates a burden for patients. However, limited research is performed on its impact on patients' daily lives. Objective The aim of this study was to explore the impact of cardiovascular medication on different daily life aspect...
journal_title:International journal of clinical pharmacy
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abstract::Background Taking regular medication has been shown to have an impact on the daily lives of patients and their families. Objective To explore the medication-related experiences of patients and their families when a child or young person is prescribed regular medication. Setting A specialist U.K. paediatric hospital. M...
journal_title:International journal of clinical pharmacy
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doi:10.1007/s11096-018-0756-z
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abstract:BACKGROUND:The scope of pharmacist services for patients with pulmonary disease has primarily focused on drug related outcomes; however pharmacists have the ability to broaden the scope of clinical services by performing diagnostic testing including quality spirometry testing. Studies have demonstrated that pharmacists...
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pub_type: 杂志文章,评审
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更新日期:2015-10-01 00:00:00
abstract::Background While dispensing prescribed medicines, pharmacists frequently encounter technical and clinical problems that require a pharmaceutical intervention. Objective To describe the pharmaceutical interventions performed by community pharmacists while dispensing prescribed medicines and to investigate, in-depth, th...
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更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:In end-of-life care, symptoms of discomfort are mainly managed by drug therapy, the guidelines for which are mainly based on expert opinions. A few papers have inventoried drug prescriptions in palliative care settings, but none has reported the frequency of use in combination with doses and route of adminis...
journal_title:International journal of clinical pharmacy
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doi:10.1007/s11096-015-0094-3
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Drug use in pregnancy is often reason of concern for mothers and their physicians. However, only few studies investigated predictors of drug use in pregnancy. OBJECTIVES:To examine maternal characteristics as predictors of medication use in the 6 months before pregnancy and during the first 6 months of preg...
journal_title:International journal of clinical pharmacy
pub_type: 杂志文章
doi:10.1007/s11096-013-9750-7
更新日期:2013-06-01 00:00:00
abstract::Background Patients' potential misconceptions and concerns about using opioids are among the primary causes of patient-related barriers that may lead to failure in pain management. These barriers can be eliminated through educational interventions, thus achieving better pain management. Objective The aim of this study...
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更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Communication between hospital and community pharmacists when a patient is discharged from hospital can improve the accuracy of medication reconciliation, thus preventing unintentional changes and ensuring continuity of supply. It allows problems to be resolved before a patient requires a further supply of m...
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doi:10.1007/s11096-013-9813-9
更新日期:2013-10-01 00:00:00
abstract:UNLABELLED:Background Potentially inappropriate medications (PIMs) are often found in high proportion among the elderly population. The STOPP criteria have been suggested to detect more PIMs in European elderly than the Beers criteria. Objective This study aimed to determine the prevalence of PIMs and potential prescri...
journal_title:International journal of clinical pharmacy
pub_type: 杂志文章,多中心研究
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更新日期:2016-10-01 00:00:00
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journal_title:International journal of clinical pharmacy
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更新日期:2018-02-01 00:00:00
abstract::Background Little is known about the extent of drug-related problems (DRPs) in community-dwelling older adult patients with chronic diseases in mainland China. Setting A medication therapy review service at a community health center in Chongqing, China. Objective To identify and categorize DRPs along with pharmacists'...
journal_title:International journal of clinical pharmacy
pub_type: 杂志文章
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更新日期:2018-04-01 00:00:00
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journal_title:International journal of clinical pharmacy
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更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:The variability in the clinical response to clopidogrel treatment has been attributed to genetic factors, but the specific genes and other risk factors remain unclear. OBJECTIVE:To investigate the incidence of high on-treatment platelet reactivity in coronary heart disease patients following clopidogrel the...
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journal_title:International journal of clinical pharmacy
pub_type: 杂志文章
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更新日期:2014-10-01 00:00:00
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journal_title:International journal of clinical pharmacy
pub_type: 杂志文章
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更新日期:2014-12-01 00:00:00
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更新日期:2021-01-07 00:00:00
abstract::Background Population-based studies investigating indications for antidepressant prescribing mostly rely on diagnoses from general practitioners. However, diagnostic codes might be incomplete and drugs may be prescribed 'off-label' for indications not investigated in clinical trials. Objective We aimed to study indica...
journal_title:International journal of clinical pharmacy
pub_type: 杂志文章
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journal_title:International journal of clinical pharmacy
pub_type: 杂志文章
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更新日期:2018-12-01 00:00:00
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journal_title:International journal of clinical pharmacy
pub_type: 杂志文章
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更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:Medication errors are a potential major threat to patient's health, and allergic reactions occurring in patients with known allergies are an important preventable form of adverse drug event. The use of penicillin antibiotics in patients who are allergic to penicillin, in particular, is a major concern. AIM:...
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pub_type: 杂志文章
doi:10.1007/s11096-012-9708-1
更新日期:2013-02-01 00:00:00
abstract::Background After radical cystectomy, delayed return of bowel function is relatively common. Although studies investigating on the best modality for delivering nutritional support to this patient group are limited, parenteral nutrition was standard of care in those patients at the urological ward of the University Hosp...
journal_title:International journal of clinical pharmacy
pub_type: 杂志文章
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更新日期:2019-04-01 00:00:00
abstract::Background In the Netherlands, a nationwide Medication Record System based on pharmacy dispensing data is used to obtain information about patients' actual medication use. However, it is not clear to what extent the information of the Nationwide Medication Record System corresponds to the medication information obtain...
journal_title:International journal of clinical pharmacy
pub_type: 杂志文章
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更新日期:2019-06-01 00:00:00
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journal_title:International journal of clinical pharmacy
pub_type: 杂志文章
doi:10.1007/s11096-015-0093-4
更新日期:2015-06-01 00:00:00